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11. 发明申请

US20090022264A1 STATIONARY X-RAY DIGITAL BREAST TOMOSYNTHESIS SYSTEMS AND RELATED METHODS 有权
标题翻译： STATIONARY X射线数字乳腺蛋白酶体系及相关方法
公开(公告)号：US20090022264A1
公开(公告)日：2009-01-22
申请号：US12176056
申请日：2008-07-18
申请人： Otto Z. Zhou , Guang Yang , Jianping Lu , David Lalush
发明人： Otto Z. Zhou , Guang Yang , Jianping Lu , David Lalush
IPC分类号： A61B6/04 , A61B6/02
CPC分类号： G06T11/006 , A61B6/025 , A61B6/4007 , A61B6/405 , A61B6/4291 , A61B6/482 , A61B6/502 , A61B6/584 , G06T2211/436
摘要： Stationary x-ray digital breast tomosynthesis systems and related methods are disclosed. According to one aspect, the subject matter described herein can include an x-ray tomosynthesis system having a plurality of stationary field emission x-ray sources configured to irradiate a location for positioning an object to be imaged with x-ray beams to generate projection images of the object. An x-ray detector can be configured to detect the projection images of the object. A projection image reconstruction function can be configured to reconstruct tomography images of the object based on the projection images of the object.
摘要翻译：公开了固定x射线数字乳房断层合成系统及相关方法。根据一个方面，本文所述的主题可以包括具有多个静止场发射x射线源的x射线断层合成系统，其被配置为照射用于利用x射线束来定位待成像对象的位置以产生投影图像的对象。 X射线检测器可被配置为检测对象的投影图像。投影图像重建功能可以被配置为基于对象的投影图像重建对象的断层摄影图像。

12. 发明授权

US07129513B2 Field emission ion source based on nanostructure-containing material 失效
标题翻译：基于纳米结构材料的场发射离子源
公开(公告)号：US07129513B2
公开(公告)日：2006-10-31
申请号：US10858436
申请日：2004-06-02
申请人： Otto Z. Zhou , Jianping Lu , Changkun Dong , Bo Gao
发明人： Otto Z. Zhou , Jianping Lu , Changkun Dong , Bo Gao
IPC分类号： H01L29/06
CPC分类号： H01J27/26 , B82Y10/00
摘要： A field emission ion source has nanostructure materials on at least an emitting edge of the anode electrode. Metal is transferred from a metal reservoir to the emitting edge of the anode, where the metal is transferred to an emitting end of the nanostructure materials and is ionized under an applied electric field. Plural ion sources can be combined to form a field emission ion source device. The numbers of emitting sources are selectable through electric or mechanical switches and different ion extraction potentials can be applied. Various nanostructure materials include: single wall carbon nanotubes and bundles, few-walled carbon nanotubes and bundles, multi-walled carbon nanotubes and bundles, and carbon fiber. Nanostructure-containing material is integrated into the anode by electrophoresis, dielectrophoresis, CVD, screen printing, and mechanical methods. Metal, preferably alkali metal, is transferred into the nanostructure-containing material by one or a combination of following intercalation methods: vapor transport, solution, electrochemical, and solid state reaction.
摘要翻译：场发射离子源在阳极电极的至少一个发射边缘上具有纳米结构材料。金属从金属储存器转移到阳极的发射边缘，其中金属被转移到纳米结构材料的发射端，并在施加的电场下被电离。多个离子源可以组合形成场发射离子源装置。发射源的数量可以通过电动或机械开关进行选择，并且可以应用不同的离子提取电位。各种纳米结构材料包括：单壁碳纳米管和束，几壁碳纳米管和束，多壁碳纳米管和束以及碳纤维。含纳米结构的材料通过电泳，介电电泳，CVD，丝网印刷和机械方法集成到阳极中。通过以下插入方法之一或组合将金属（优选碱金属）转移到含纳米结构的材料中：蒸气转移，溶液，电化学和固态反应。

13. 发明授权

US06553096B1 X-ray generating mechanism using electron field emission cathode 有权
公开(公告)号：US06553096B1
公开(公告)日：2003-04-22
申请号：US09679303
申请日：2000-10-06
申请人： Otto Z. Zhou , Jianping Lu
发明人： Otto Z. Zhou , Jianping Lu
IPC分类号： H01J37073
CPC分类号： H01J35/14 , A61B6/032 , A61B6/4021 , A61B6/4028 , A61B6/405 , A61B6/4488 , A61B6/482 , B82Y10/00 , H01J35/065 , H01J35/22 , H01J2201/30469 , H01J2235/064 , H01J2235/068 , H05G1/34 , Y10S977/939
摘要： An x-ray generating device includes a field emission cathode formed at least partially from a nanostructure-containing material having an emitted electron current density of at least 4 A/cm2. High energy conversion efficiency and compact design are achieved due to easy focusing of cold cathode emitted electrons and dramatic reduction of heating at the anode. In addition, by pulsing the field between the cathode and the gate or anode and focusing the electron beams at different anode materials, pulsed x-ray radiation with varying energy can be generated from a single device.

14. 发明授权

US07618300B2 Method of synthesizing small-diameter carbon nanotubes with electron field emission properties 有权
标题翻译：合成具有电子场发射特性的小直径碳纳米管的方法
公开(公告)号：US07618300B2
公开(公告)日：2009-11-17
申请号：US11012341
申请日：2004-12-16
申请人： Jie Liu , Chunsheng Du , Cheng Qian , Bo Gao , Qi Qiu , Otto Z. Zhou
发明人： Jie Liu , Chunsheng Du , Cheng Qian , Bo Gao , Qi Qiu , Otto Z. Zhou
IPC分类号： H01J1/304
CPC分类号： H01J9/025 , B82Y10/00 , B82Y30/00 , B82Y40/00 , C01B32/162 , C01B2202/04 , C01B2202/36 , H01J1/304 , H01J2201/30469
摘要： Carbon nanotube material having an outer diameter less than 10 nm and a number of walls less than ten are disclosed. Also disclosed are an electron field emission device including a substrate, an optionally layer of adhesion-promoting layer, and a layer of electron field emission material. The electron field emission material includes a carbon nanotube having a number of concentric graphene shells per tube of from two to ten, an outer diameter from 2 to 8 nm, and a nanotube length greater than 0.1 microns. One method to fabricate carbon nanotubes includes the steps of (a) producing a catalyst containing Fe and Mo supported on MgO powder, (b) using a mixture of hydrogen and carbon containing gas as precursors, and (c) heating the catalyst to a temperature above 950° C. to produce a carbon nanotube. Another method of fabricating an electron field emission cathode includes the steps of (a) synthesizing electron field emission materials containing carbon nanotubes with a number of concentric graphene shells per tube from two to ten, an outer diameter of from 2 to 8 nm, and a length greater than 0.1 microns, (b) dispersing the electron field emission material in a suitable solvent, (c) depositing the electron field emission materials onto a substrate, and (d) annealing the substrate.
摘要翻译：公开了外径小于10nm，壁数小于10的碳纳米管材料。还公开了一种电子场发射器件，其包括衬底，任选层的粘附促进层和电子场发射材料层。电子场发射材料包括碳纳米管，每个管具有多至2个至10个，外径为2至8nm的多个同心石墨烯壳，纳米管长度大于0.1微米。一种制造碳纳米管的方法包括以下步骤：（a）制备负载在MgO粉末上的含有Fe和Mo的催化剂，（b）使用氢气和含碳气体的混合物作为前体，和（c）将催化剂加热至高于950℃以产生碳纳米管。制造电子场发射阴极的另一种方法包括以下步骤：（a）合成含有碳纳米管的电子场发射材料，每个管具有多个同心石墨烯，每个管数为2至10个，外径为2至8nm，长度大于0.1微米，（b）将电子场发射材料分散在合适的溶剂中，（c）将电子场发射材料沉积到衬底上，和（d）使衬底退火。

15. 发明授权

US07826595B2 Micro-focus field emission x-ray sources and related methods 有权
标题翻译：微焦场发射X射线源及相关方法
公开(公告)号：US07826595B2
公开(公告)日：2010-11-02
申请号：US11717590
申请日：2007-03-13
申请人： Zejian Liu , Otto Z. Zhou , Jianping Lu
发明人： Zejian Liu , Otto Z. Zhou , Jianping Lu
IPC分类号： H01J23/04
CPC分类号： H01J35/065 , H01J35/14 , H01J2235/062
摘要： Micro-focus field emission x-ray sources and related methods are provided. A micro-focus field emission x-ray source can include a field emission cathode including a film with a layer of electron field emitting materials patterned on a conducting surface. Further, the x-ray source can include a gate electrode for extracting field emitted electrons from the cathode when a bias electrical field is applied between the gate electrode and the cathode. The x-ray source can also include an anode. Further, the x-ray source can include an electrostatic focusing unit between the gate electrode and anode. The electrostatic focusing unit can include multiple focusing electrodes that are electrically separated from each other. Each of the electrodes can have an independently adjustable electrical potential. A controller can be configured to adjust at least one of the electrical potentials of the focusing electrodes and to adjust a size of the cathode.
摘要翻译：提供微焦场发射x射线源及相关方法。微焦点场发射x射线源可以包括场致发射阴极，其包括具有在导电表面上图案化的电子场发射材料层的膜。此外，当在栅电极和阴极之间施加偏置电场时，x射线源可以包括用于从阴极提取场发射的电子的栅电极。 x射线源还可以包括阳极。此外，x射线源可以包括在栅电极和阳极之间的静电聚焦单元。静电聚焦单元可以包括彼此电分离的多个聚焦电极。每个电极可以具有独立可调的电位。控制器可以被配置为调节聚焦电极的至少一个电位并调整阴极的尺寸。

16. 发明授权

US07245692B2 X-ray imaging systems and methods using temporal digital signal processing for reducing noise and for obtaining multiple images simultaneously 有权
标题翻译： X射线成像系统和使用时间数字信号处理以减少噪声并同时获得多个图像的方法
公开(公告)号：US07245692B2
公开(公告)日：2007-07-17
申请号：US11410997
申请日：2006-04-25
申请人： Jianping Lu , Otto Z. Zhou , Jian Zhang
发明人： Jianping Lu , Otto Z. Zhou , Jian Zhang
IPC分类号： A61B6/03
CPC分类号： G01N23/04 , G01N2223/204 , G01N2223/419
摘要： X-ray imaging systems and methods are provided that use temporal digital signal processing for reducing noise and for obtaining multiple images simultaneously. An x-ray imaging system can include an x-ray source adapted to generate a pulsed x-ray beam having a predetermined frequency and apply the pulsed x-ray beam to an object to be imaged. An x-ray detector can be adapted to detect x-ray radiation from the object and generate temporal data based on the x-ray radiation. A temporal data analyzer can be adapted to apply a temporal signal process to the temporal data to remove at least a portion of the temporal data having a different frequency than the predetermined frequency.
摘要翻译：提供了使用时间数字信号处理来降低噪声并同时获得多个图像的X射线成像系统和方法。 x射线成像系统可以包括适于产生具有预定频率的脉冲X射线束的x射线源，并将脉冲X射线束施加到待成像对象。 X射线检测器可以适于检测来自物体的X射线辐射，并且基于x射线辐射产生时间数据。时间数据分析器可以适于对时间数据应用时间信号处理以去除具有与预定频率不同的频率的时间数据的至少一部分。

17. 发明授权

US06850595B2 X-ray generating mechanism using electron field emission cathode 有权
标题翻译：使用电子场发射阴极的X射线发生机构
公开(公告)号：US06850595B2
公开(公告)日：2005-02-01
申请号：US10309126
申请日：2002-12-04
申请人： Otto Z. Zhou , Jianping Lu
发明人： Otto Z. Zhou , Jianping Lu
IPC分类号： G21K5/02 , A61B6/00 , A61B6/03 , G21K5/08 , H01J35/06 , H01J35/08 , H05G1/00 , H05G1/34 , H01J9/12
CPC分类号： H01J35/14 , A61B6/032 , A61B6/4021 , A61B6/4028 , A61B6/405 , A61B6/4488 , A61B6/482 , B82Y10/00 , H01J35/065 , H01J35/22 , H01J2201/30469 , H01J2235/064 , H01J2235/068 , H05G1/34 , Y10S977/939
摘要： An x-ray generating device includes a field emission cathode formed at least partially from a nanostructure-containing material having an emitted electron current density of at least 4 A/cm2. High energy conversion efficiency and compact design are achieved due to easy focusing of cold cathode emitted electrons and dramatic reduction of heating at the anode. In addition, by pulsing the field between the cathode and the gate or anode and focusing the electron beams at different anode materials, pulsed x-ray radiation with varying energy can be generated from a single device.
摘要翻译： x射线产生装置包括至少部分地由具有至少4A / cm 2的发射电子密度的纳米结构材料形成的场致发射阴极。由于容易聚焦冷阴极发射电子并显着降低阳极的加热，因此实现了高能量转换效率和紧凑设计。此外，通过在阴极和栅极或阳极之间脉冲电场并将电子束聚焦在不同的阳极材料处，可以从单个器件产生具有变化能量的脉冲X射线辐射。

18. 发明授权

US06969690B2 Methods and apparatus for patterned deposition of nanostructure-containing materials by self-assembly and related articles 有权
标题翻译：通过自组装和相关制品图案化沉积纳米结构材料的方法和装置
公开(公告)号：US06969690B2
公开(公告)日：2005-11-29
申请号：US10803639
申请日：2004-03-18
申请人： Otto Z. Zhou , Soojin Oh , Jian Zhang , Yuan Cheng , Hideo Shimoda
发明人： Otto Z. Zhou , Soojin Oh , Jian Zhang , Yuan Cheng , Hideo Shimoda
IPC分类号： B05D1/00 , B05D1/02 , B05D1/18 , B05D3/06 , B05D5/08 , C25D20060101 , G03F7/40 , H01J9/02 , H01L21/26 , H01L21/469 , H01L21/76
CPC分类号： H01J9/025 , B05D1/002 , B05D1/02 , B05D1/18 , B05D1/185 , B05D3/065 , B05D3/068 , B05D5/08 , B05D2203/35 , B82Y10/00 , B82Y30/00 , B82Y40/00 , G03F7/40 , G03F7/405 , H01J2201/30469 , Y10S977/883
摘要： Methods and apparatus are described for patterned deposition of nanostructure-containing materials by self-assembly and related articles. According to an exemplary embodiment self-assembly method for depositing nanostructure-containing materials includes forming a nanostructure-containing material. The nanostructure-containing material is chemically functionalized and dispersed in a liquid medium to form a suspension. At least a portion of a substrate having a surface that can attract the functionalized nanostructure-containing material is brought into contact with the suspension. The substrate is separated from the suspension. The nanostructure-containing material adheres to the portion of the substrate when separated from the suspension. According to another exemplary embodiment, hydrophilic and hydrophobic regions are formed on the surface of the substrate before bringing the substrate into contact with the suspension. The functionalized nanostructure-containing material is hydrophilic and adheres to the hydrophilic region of the substrate when separated from the suspension.
摘要翻译：描述了通过自组装和相关制品图案化沉积纳米结构材料的方法和装置。根据示例性实施例，用于沉积含纳米结构的材料的自组装方法包括形成含纳米结构的材料。将含纳米结构的材料化学功能化并分散在液体介质中以形成悬浮液。具有能够吸引官能化的纳米结构材料的表面的基材的至少一部分与悬浮液接触。将底物与悬浮液分离。当与悬浮液分离时，含纳米结构的材料粘附到基底的一部分。根据另一示例性实施方案，在使基材与悬浮液接触之前，在基材的表面上形成亲水和疏水区域。当与悬浮液分离时，含官能化纳米结构的材料是亲水性的并且粘附到基底的亲水区域。

19. 发明申请

US20100329413A1 COMPACT MICROBEAM RADIATION THERAPY SYSTEMS AND METHODS FOR CANCER TREATMENT AND RESEARCH 有权
标题翻译：紧凑型微波辐射治疗系统和癌症治疗与研究方法
公开(公告)号：US20100329413A1
公开(公告)日：2010-12-30
申请号：US12688425
申请日：2010-01-15
申请人： Otto Z. Zhou , Sha X. Chang
发明人： Otto Z. Zhou , Sha X. Chang
IPC分类号： A61N5/10 , A61B6/03 , A61B6/00
CPC分类号： A61N5/1069 , A61B6/508 , A61N5/10 , A61N5/1042
摘要： The present subject matter relates to compact, non-synchrotron microbeam radiation therapy (MRT) systems and methods for cancer research and treatment based on a carbon nanotube distributed x-ray source array technology. The systems and methods can deliver microscopically discrete x-ray radiation at peak dose rate of 10 Gy per second or higher. The x-ray radiation can be provided by a spatially distributed x-ray source array. The technology can be used, for example and without limitation, for human cancer treatment, for intra-operative radiation therapy, and for pre-clinical cancer research on animal cancer models.
摘要翻译：本发明涉及基于碳纳米管分布式x射线源阵列技术的紧凑的非同步加速器微束放射治疗（MRT）系统和用于癌症研究和治疗的方法。系统和方法可以以10Gy /秒或更高的峰值剂量率递送显微分立的X射线辐射。 X射线辐射可由空间分布的x射线源阵列提供。该技术可用于例如但不限于人类癌症治疗，术中放射治疗和用于动物癌症模型的临床前癌症研究。

20. 发明授权

US07252749B2 Deposition method for nanostructure materials 有权
标题翻译：纳米结构材料的沉积方法
公开(公告)号：US07252749B2
公开(公告)日：2007-08-07
申请号：US09996695
申请日：2001-11-30
申请人： Otto Z. Zhou , Bo Gao , Guozhen Yue , Soojin Oh
发明人： Otto Z. Zhou , Bo Gao , Guozhen Yue , Soojin Oh
IPC分类号： C25D13/02
CPC分类号： C25D13/00 , B82Y30/00 , C25D15/00
摘要： A method for depositing a coating of a nanostructure material onto a substrate includes: (1) forming a solution or suspension of containing the nanostructure material; (2) selectively adding “chargers” to the solution; (3) immersing electrodes in the solution, the substrate upon which the nanostructure material is to be deposited acting as one of the electrodes; (4) applying a direct and/or alternating current electrical field between the two electrodes for a certain period of time thereby causing the nanostructure materials in the solution to migrate toward and attach themselves to the substrate electrode; and (5) subsequent optional processing of the coated substrate.
摘要翻译：将纳米结构材料的涂层沉积在基材上的方法包括：（1）形成含有纳米结构材料的溶液或悬浮液; （2）选择性地将“充电器”添加到解决方案中; （3）将电极浸渍在溶液中，沉积纳米结构材料的基板作为其中一个电极; （4）在两个电极之间施加直接和/或交流的电场一段时间，从而导致溶液中的纳米结构材料迁移并附着到衬底电极上; 和（5）随后可选地处理涂覆的基底。

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