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1. 发明授权

US07826595B2 Micro-focus field emission x-ray sources and related methods 有权
标题翻译：微焦场发射X射线源及相关方法
公开(公告)号：US07826595B2
公开(公告)日：2010-11-02
申请号：US11717590
申请日：2007-03-13
申请人： Zejian Liu , Otto Z. Zhou , Jianping Lu
发明人： Zejian Liu , Otto Z. Zhou , Jianping Lu
IPC分类号： H01J23/04
CPC分类号： H01J35/065 , H01J35/14 , H01J2235/062
摘要： Micro-focus field emission x-ray sources and related methods are provided. A micro-focus field emission x-ray source can include a field emission cathode including a film with a layer of electron field emitting materials patterned on a conducting surface. Further, the x-ray source can include a gate electrode for extracting field emitted electrons from the cathode when a bias electrical field is applied between the gate electrode and the cathode. The x-ray source can also include an anode. Further, the x-ray source can include an electrostatic focusing unit between the gate electrode and anode. The electrostatic focusing unit can include multiple focusing electrodes that are electrically separated from each other. Each of the electrodes can have an independently adjustable electrical potential. A controller can be configured to adjust at least one of the electrical potentials of the focusing electrodes and to adjust a size of the cathode.
摘要翻译：提供微焦场发射x射线源及相关方法。微焦点场发射x射线源可以包括场致发射阴极，其包括具有在导电表面上图案化的电子场发射材料层的膜。此外，当在栅电极和阴极之间施加偏置电场时，x射线源可以包括用于从阴极提取场发射的电子的栅电极。 x射线源还可以包括阳极。此外，x射线源可以包括在栅电极和阳极之间的静电聚焦单元。静电聚焦单元可以包括彼此电分离的多个聚焦电极。每个电极可以具有独立可调的电位。控制器可以被配置为调节聚焦电极的至少一个电位并调整阴极的尺寸。

2. 发明授权

US08155262B2 Methods, systems, and computer program products for multiplexing computed tomography 有权
标题翻译：用于复用计算机断层扫描的方法，系统和计算机程序产品
公开(公告)号：US08155262B2
公开(公告)日：2012-04-10
申请号：US11526217
申请日：2006-09-22
申请人： Otto Z. Zhou , Jianping Lu , Jian Zhang , Guang Yang , Yueh Lee , Qi Qiu , Yuan Cheng
发明人： Otto Z. Zhou , Jianping Lu , Jian Zhang , Guang Yang , Yueh Lee , Qi Qiu , Yuan Cheng
IPC分类号： A61B6/03
CPC分类号： G01N23/04 , G01N2223/204 , G01N2223/419
摘要： Methods, systems, and computer program products for multiplexing computed tomography are disclosed. According to one aspect, the subject matter described herein can include illuminating an object with a plurality of x-ray beams from a plurality of viewing angles, wherein each x-ray beam has a distinct waveform; detecting the x-ray intensities of the plurality of pulsed x-ray beams as a function of time, and extracting individual projection image data from the detected x-ray intensities based on the distinct waveforms of the x-ray beams for combining the projection image data to generate three-dimensional tomographic image data of the object.
摘要翻译：公开了用于复用计算机断层摄影的方法，系统和计算机程序产品。根据一个方面，本文描述的主题可以包括用多个视角对多个X射线束照射物体，其中每个X射线束具有不同的波形; 检测作为时间的函数的多个脉冲X射线束的x射线强度，并且基于用于组合投影图像的x射线束的不同波形从检测到的x射线强度中提取各个投影图像数据数据以产生对象的三维断层图像数据。

3. 发明授权

US07751528B2 Stationary x-ray digital breast tomosynthesis systems and related methods 有权
标题翻译：固定x射线数字乳房断层合成系统及相关方法
公开(公告)号：US07751528B2
公开(公告)日：2010-07-06
申请号：US12176056
申请日：2008-07-18
申请人： Otto Z. Zhou , Guang Yang , Jianping Lu , David Lalush
发明人： Otto Z. Zhou , Guang Yang , Jianping Lu , David Lalush
IPC分类号： A61B6/04
CPC分类号： G06T11/006 , A61B6/025 , A61B6/4007 , A61B6/405 , A61B6/4291 , A61B6/482 , A61B6/502 , A61B6/584 , G06T2211/436
摘要： Stationary x-ray digital breast tomosynthesis systems and related methods are disclosed. According to one aspect, the subject matter described herein can include an x-ray tomosynthesis system having a plurality of stationary field emission x-ray sources configured to irradiate a location for positioning an object to be imaged with x-ray beams to generate projection images of the object. An x-ray detector can be configured to detect the projection images of the object. A projection image reconstruction function can be configured to reconstruct tomography images of the object based on the projection images of the object.
摘要翻译：公开了固定x射线数字乳房断层合成系统及相关方法。根据一个方面，本文所述的主题可以包括具有多个固定场发射x射线源的x射线断层合成系统，其被配置为照射用于利用X射线束定影要成像的物体的位置以产生投影图像的对象。 X射线检测器可被配置为检测对象的投影图像。投影图像重建功能可以被配置为基于对象的投影图像重建对象的断层摄影图像。

4. 发明授权

US07082182B2 Computed tomography system for imaging of human and small animal 有权
公开(公告)号：US07082182B2
公开(公告)日：2006-07-25
申请号：US10923385
申请日：2004-08-20
申请人： Otto Z. Zhou , Jianping Lu , Yueh Lee , Weili Lin , Yuan Cheng , Jian Zhang
发明人： Otto Z. Zhou , Jianping Lu , Yueh Lee , Weili Lin , Yuan Cheng , Jian Zhang
IPC分类号： G01N23/00
CPC分类号： B82Y10/00 , A61B6/032 , A61B6/4028 , A61B6/508 , A61B6/541 , G01N23/046 , G01N2223/316 , G01N2223/419 , G01N2223/612 , H01J35/065 , H01J2201/30469 , H01J2235/068
摘要： Computed tomography device comprising an x-ray source and an x-ray detecting unit. The x-ray source comprises a cathode with a plurality of individually programmable electron emitting units that each emit an electron upon an application of an electric field, an anode target that emits an x-ray upon impact by the emitted electron, and a collimator. Each electron emitting unit includes an electron field emitting material. The electron field emitting material includes a nanostructured material or a plurality of nanotubes or a plurality of nanowires. Computed tomography methods are also provided.

5. 发明授权

US08189893B2 Methods, systems, and computer program products for binary multiplexing x-ray radiography 有权
标题翻译：用于二进制复用x射线摄影的方法，系统和计算机程序产品
公开(公告)号：US08189893B2
公开(公告)日：2012-05-29
申请号：US11804897
申请日：2007-05-21
申请人： Jian Zhang , Jianping Lu , Otto Z. Zhou , David Lalush
发明人： Jian Zhang , Jianping Lu , Otto Z. Zhou , David Lalush
IPC分类号： G06K9/00 , H05G1/60
CPC分类号： H01J35/14 , A61B6/00 , A61B6/032 , A61B6/4021 , A61B6/405 , A61B6/482 , G06T11/005 , G06T2211/408 , H01J35/065 , H01J2235/062 , H01J2235/068 , H05G1/52
摘要： Methods, systems, and computer program products for binary multiplexing x-ray radiography are disclosed. According to one aspect, the subject matter described herein can include irradiating an object with composite x-ray beams including signals based on a predetermined binary transform. Further, the subject matter described herein can include detecting x-ray intensities associated with the signals of the composite x-ray beams. An inverse binary transform can be applied to the detected x-ray intensities associated with the signals of the composite x-ray beams to recover the signals of the composite x-ray beams.
摘要翻译：公开了用于二进制复用x射线照相术的方法，系统和计算机程序产品。根据一个方面，本文描述的主题可以包括用包含基于预定二进制变换的信号的复合X射线束照射物体。此外，本文描述的主题可以包括检测与复合x射线束的信号相关联的x射线强度。可以对与复合x射线束的信号相关联的检测到的x射线强度应用逆二值变换以恢复复合x射线束的信号。

6. 发明申请

US20090022264A1 STATIONARY X-RAY DIGITAL BREAST TOMOSYNTHESIS SYSTEMS AND RELATED METHODS 有权
标题翻译： STATIONARY X射线数字乳腺蛋白酶体系及相关方法
公开(公告)号：US20090022264A1
公开(公告)日：2009-01-22
申请号：US12176056
申请日：2008-07-18
申请人： Otto Z. Zhou , Guang Yang , Jianping Lu , David Lalush
发明人： Otto Z. Zhou , Guang Yang , Jianping Lu , David Lalush
IPC分类号： A61B6/04 , A61B6/02
CPC分类号： G06T11/006 , A61B6/025 , A61B6/4007 , A61B6/405 , A61B6/4291 , A61B6/482 , A61B6/502 , A61B6/584 , G06T2211/436
摘要： Stationary x-ray digital breast tomosynthesis systems and related methods are disclosed. According to one aspect, the subject matter described herein can include an x-ray tomosynthesis system having a plurality of stationary field emission x-ray sources configured to irradiate a location for positioning an object to be imaged with x-ray beams to generate projection images of the object. An x-ray detector can be configured to detect the projection images of the object. A projection image reconstruction function can be configured to reconstruct tomography images of the object based on the projection images of the object.
摘要翻译：公开了固定x射线数字乳房断层合成系统及相关方法。根据一个方面，本文所述的主题可以包括具有多个静止场发射x射线源的x射线断层合成系统，其被配置为照射用于利用x射线束来定位待成像对象的位置以产生投影图像的对象。 X射线检测器可被配置为检测对象的投影图像。投影图像重建功能可以被配置为基于对象的投影图像重建对象的断层摄影图像。

7. 发明授权

US07129513B2 Field emission ion source based on nanostructure-containing material 失效
标题翻译：基于纳米结构材料的场发射离子源
公开(公告)号：US07129513B2
公开(公告)日：2006-10-31
申请号：US10858436
申请日：2004-06-02
申请人： Otto Z. Zhou , Jianping Lu , Changkun Dong , Bo Gao
发明人： Otto Z. Zhou , Jianping Lu , Changkun Dong , Bo Gao
IPC分类号： H01L29/06
CPC分类号： H01J27/26 , B82Y10/00
摘要： A field emission ion source has nanostructure materials on at least an emitting edge of the anode electrode. Metal is transferred from a metal reservoir to the emitting edge of the anode, where the metal is transferred to an emitting end of the nanostructure materials and is ionized under an applied electric field. Plural ion sources can be combined to form a field emission ion source device. The numbers of emitting sources are selectable through electric or mechanical switches and different ion extraction potentials can be applied. Various nanostructure materials include: single wall carbon nanotubes and bundles, few-walled carbon nanotubes and bundles, multi-walled carbon nanotubes and bundles, and carbon fiber. Nanostructure-containing material is integrated into the anode by electrophoresis, dielectrophoresis, CVD, screen printing, and mechanical methods. Metal, preferably alkali metal, is transferred into the nanostructure-containing material by one or a combination of following intercalation methods: vapor transport, solution, electrochemical, and solid state reaction.
摘要翻译：场发射离子源在阳极电极的至少一个发射边缘上具有纳米结构材料。金属从金属储存器转移到阳极的发射边缘，其中金属被转移到纳米结构材料的发射端，并在施加的电场下被电离。多个离子源可以组合形成场发射离子源装置。发射源的数量可以通过电动或机械开关进行选择，并且可以应用不同的离子提取电位。各种纳米结构材料包括：单壁碳纳米管和束，几壁碳纳米管和束，多壁碳纳米管和束以及碳纤维。含纳米结构的材料通过电泳，介电电泳，CVD，丝网印刷和机械方法集成到阳极中。通过以下插入方法之一或组合将金属（优选碱金属）转移到含纳米结构的材料中：蒸气转移，溶液，电化学和固态反应。

8. 发明授权

US06553096B1 X-ray generating mechanism using electron field emission cathode 有权
公开(公告)号：US06553096B1
公开(公告)日：2003-04-22
申请号：US09679303
申请日：2000-10-06
申请人： Otto Z. Zhou , Jianping Lu
发明人： Otto Z. Zhou , Jianping Lu
IPC分类号： H01J37073
CPC分类号： H01J35/14 , A61B6/032 , A61B6/4021 , A61B6/4028 , A61B6/405 , A61B6/4488 , A61B6/482 , B82Y10/00 , H01J35/065 , H01J35/22 , H01J2201/30469 , H01J2235/064 , H01J2235/068 , H05G1/34 , Y10S977/939
摘要： An x-ray generating device includes a field emission cathode formed at least partially from a nanostructure-containing material having an emitted electron current density of at least 4 A/cm2. High energy conversion efficiency and compact design are achieved due to easy focusing of cold cathode emitted electrons and dramatic reduction of heating at the anode. In addition, by pulsing the field between the cathode and the gate or anode and focusing the electron beams at different anode materials, pulsed x-ray radiation with varying energy can be generated from a single device.

9. 发明申请

US20100239064A1 Methods, systems, and computer program products for multiplexing computed tomography 有权
标题翻译：用于复用计算机断层扫描的方法，系统和计算机程序产品
公开(公告)号：US20100239064A1
公开(公告)日：2010-09-23
申请号：US11526217
申请日：2006-09-22
申请人： Otto Z. Zhou , Jianping Lu , Jian Zhang , Guang Yang , Yueh Lee , Qi Qiu , Yuan Cheng
发明人： Otto Z. Zhou , Jianping Lu , Jian Zhang , Guang Yang , Yueh Lee , Qi Qiu , Yuan Cheng
IPC分类号： A61B6/03 , G06K9/00
CPC分类号： G01N23/04 , G01N2223/204 , G01N2223/419
摘要： Methods, systems, and computer program products for multiplexing computed tomography are disclosed. According to one aspect, the subject matter described herein can include illuminating an object with a plurality of x-ray beams from a plurality of viewing angles, wherein each x-ray beam has a distinct waveform; detecting the x-ray intensities of the plurality of pulsed x-ray beams as a function of time, and extracting individual projection image data from the detected x-ray intensities based on the distinct waveforms of the x-ray beams for combining the projection image data to generate three-dimensional tomographic image data of the object.
摘要翻译：公开了用于复用计算机断层摄影的方法，系统和计算机程序产品。根据一个方面，本文描述的主题可以包括用多个视角对多个X射线束照射物体，其中每个X射线束具有不同的波形; 检测作为时间的函数的多个脉冲X射线束的x射线强度，并且基于用于组合投影图像的x射线束的不同波形从检测到的x射线强度中提取各个投影图像数据数据以产生对象的三维断层图像数据。

10. 发明授权

US07486772B2 Systems and methods for x-ray imaging and scanning of objects 有权
标题翻译：用于x射线成像和物体扫描的系统和方法
公开(公告)号：US07486772B2
公开(公告)日：2009-02-03
申请号：US11601577
申请日：2006-11-17
申请人： Jianping Lu , Otto Z. Zhou , Qi Qiu
发明人： Jianping Lu , Otto Z. Zhou , Qi Qiu
IPC分类号： G01N23/201
CPC分类号： H01J35/065 , G01N23/203 , H01J35/24 , H01J2235/062 , H01J2235/068
摘要： Systems and methods for x-ray imaging and scanning of objects are disclosed. According to one aspect, the subject matter described herein can include providing an x-ray source configured to generate a plurality of individually-controllable x-ray beams, positioning an object to be imaged in a path for intercepting at least one of the x-ray beams, activating the x-ray source, detecting intensities of the emitted x-ray beams, and generating imaging data based on the intensities for constructing an image of the object.
摘要翻译：公开了用于x射线成像和物体扫描的系统和方法。根据一个方面，本文描述的主题可以包括提供被配置为产生多个可单独控制的X射线束的X射线源，将要成像的对象定位在用于截取x射线束中的至少一个的路径中，激活X射线源，检测发射的X射线束的强度，以及基于用于构建物体的图像的强度来生成成像数据。

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