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11. 发明申请

US20060102856A1 Particle beam irradiation system 有权
标题翻译：粒子束照射系统
公开(公告)号：US20060102856A1
公开(公告)日：2006-05-18
申请号：US11273392
申请日：2005-11-15
申请人： Koji Matsuda , Takahide Nakayama
发明人： Koji Matsuda , Takahide Nakayama
IPC分类号： G21K5/10
CPC分类号： A61N5/1043 , A61N5/1048 , A61N2005/1087
摘要： A particle beam irradiation system capable of ensuring a more uniform dose distribution at an irradiation object even when a certain time is required from output of a beam extraction stop signal to the time when extraction of a charged particle beam from an accelerator is actually stopped. The particle beam irradiation system comprises a synchrotron, an irradiation device including scanning magnets and outputting an ion beam extracted from the synchrotron, and a control unit. The control unit stops the output of the ion beam from the irradiation device in accordance with the beam extraction stop signal, controls the scanning magnets to change an exposure position in a state in which the output of the ion beam is stopped, and after the change of the exposure position, starts the output of the ion beam from the irradiation device again. The control unit further outputs a next beam extraction stop signal when an increment of dose integrated from the time of a preceding beam extraction stop signal as a start point reaches a setting dose stored in advance.
摘要翻译：即使从射束提取停止信号的输出到从加速器的带电粒子束的提取实际停止的时刻，即使在需要一定时间的情况下，能够确保照射对象的剂量分布更均匀的粒子束照射系统。粒子束照射系统包括同步加速器，包括扫描磁体并输出从同步加速器提取的离子束的照射装置和控制单元。控制单元根据光束提取停止信号停止来自照射装置的离子束的输出，控制扫描磁体在离子束的输出停止的状态下改变曝光位置，并且在改变之后的曝光位置，再次从照射装置开始离子束的输出。当从作为起始点的先前光束提取停止信号的时间积分的剂量的增量达到预先存储的设定剂量时，控制单元还输出下一个光束提取停止信号。

12. 发明申请

US20050145804A1 Particle beam irradiation system and method of adjusting irradiation apparatus 有权
标题翻译：粒子束照射系统及照射装置调整方法
公开(公告)号：US20050145804A1
公开(公告)日：2005-07-07
申请号：US11052195
申请日：2005-02-08
申请人： Masaki Yanagisawa , Hiroshi Akiyama , Koji Matsuda , Hisataka Fujimaki
发明人： Masaki Yanagisawa , Hiroshi Akiyama , Koji Matsuda , Hisataka Fujimaki
IPC分类号： G21K1/093 , G21K5/04 , A61N5/10 , G21K1/10 , G21K3/00 , G21K5/00 , H05H13/04 , H01J37/08 , A61N5/00
CPC分类号： A61N5/1042 , A61N2005/1087 , A61N2005/1095 , G21K1/10 , G21K5/04
摘要： The present invention provides an increased degree of uniformity of radiation dose distribution for the interior of a diseased part. A particle beam therapy system includes a charged particle beam generation apparatus and an irradiation apparatus. An ion beam is generated by the charged particle beam generation apparatus. The irradiation apparatus exposes a diseased part to the generated ion beam. A scattering device, a range adjustment device, and a Bragg peak spreading device are installed upstream of a first scanning magnet and a second scanning magnet. The scattering device and the range adjustment device are combined together and moved along a beam axis, whereas the Bragg peak spreading device is moved independently along the beam axis. The scattering device moves to adjust the degree of ion beam scattering. The range adjustment device moves to adjust ion beam scatter changes caused by an absorber thickness adjustment. The Bragg peak spreading device moves to adjust ion beam scatter changes arising out of an SOBP device. These adjustments provide uniformity of radiation dose distribution for the diseased part.
摘要翻译：本发明提供了患病部位的内部的辐射剂量分布的增加的均匀度。粒子束治疗系统包括带电粒子束产生装置和照射装置。由带电粒子束产生装置产生离子束。照射装置将患病部分暴露于产生的离子束。散射装置，量程调节装置和布拉格峰扩展装置安装在第一扫描磁体和第二扫描磁体的上游。散射装置和范围调节装置组合在一起并沿着光束轴线移动，而布拉格峰扩展装置沿着光束轴线独立地移动。散射装置移动以调节离子束散射的程度。范围调整装置移动以调节由吸收体厚度调整引起的离子束散射变化。布拉格峰扩展装置移动以调整由SOBP装置引起的离子束散射变化。这些调整提供了患病部位的辐射剂量分布的均匀性。

13. 发明授权

US6087670A Synchrotron type accelerator and medical treatment system employing the same 有权
标题翻译：同步加速器和采用该加速器的医疗系统
公开(公告)号：US6087670A
公开(公告)日：2000-07-11
申请号：US365835
申请日：1999-08-03
申请人： Kazuo Hiramoto , Masumi Umezawa , Koji Matsuda
发明人： Kazuo Hiramoto , Masumi Umezawa , Koji Matsuda
IPC分类号： H05H7/04 , A61N5/10 , H05H7/10 , H05H13/04
CPC分类号： H05H13/04 , H05H7/10 , A61N2005/1087
摘要： A synchrotron type accelerator including a deflecting electromagnet arranged on a circulating orbit of a charged particle beam, four-pole divergence electromagnets and four-pole convergence electromagnets arranged on said circulating orbit. A high frequency applying unit arranged on the circulating orbit for applying a high frequency electromagnetic field to the charged particle beam circulating and for increasing an amplitude of betatron oscillation of the particle beam to a level above a stability limit of resonance. A first deflector for beam ejection arranged on the circulating orbit for deflecting the charged particle beam excited above the stability limit of the resonance by the high frequency applying unit and a second deflector for beam ejection arranged on the circulating orbit used in pairs with the first deflector for beam ejection for introducing the charged particle beam deflected by the first deflector for beam ejection into an ejected beam transporting system. The deflecting electromagnet and the second deflector for beam ejection are arranged in this order at downstream with respect to the first deflector for beam ejection, and the four-pole divergence electromagnets are arranged at downstream with respect to the first deflector for beam ejection and upstream with respect to the deflecting electromagnet and at downstream with respect to the deflecting electromagnet and upstream with respect to the second deflector for beam ejection.
摘要翻译：包括设置在带电粒子束的循环轨道上的偏转电磁体的同步加速器型加速器，设置在所述循环轨道上的四极发散电磁体和四极收敛电磁体。布置在循环轨道上的高频施加单元，用于将高频电磁场施加到带电粒子束循环，并将粒子束的贝塔振荡幅度提高到高于谐振稳定极限的水平。用于射流喷射的第一偏转器，布置在循环轨道上，用于偏转由高频施加单元激发的高于谐振稳定极限的带电粒子束，以及布置在与第一偏转器成对使用的循环轨道上的用于射束的第二偏转器用于射出用于引入由第一偏转器偏转的带电粒子束，用于射束射出到射出的束传输系统中。用于射束的偏转电磁体和第二偏转器相对于第一偏转器在下游依次布置以用于射束，并且四极分支电磁体相对于第一偏转器布置在下游，用于射出射流，并且在上游具有相对于偏转电磁体并且在相对于偏转电磁体的下游以及相对于第二偏转器的上游，用于射束。

14. 发明授权

US5198825A Reception system for a motor vehicle 失效
标题翻译：汽车接收系统
公开(公告)号：US5198825A
公开(公告)日：1993-03-30
申请号：US657629
申请日：1991-02-21
申请人： Kaoru Sakurai , Harunori Murakami , Hiroshi Iijima , Masaru Maeda , Koji Matsuda
发明人： Kaoru Sakurai , Harunori Murakami , Hiroshi Iijima , Masaru Maeda , Koji Matsuda
IPC分类号： H01Q1/12
CPC分类号： H01Q1/1278
摘要： An inductance element is arranged to parallel resonate with a ground stray capacitance component of an antenna element on a motor vehicle and a feeder cable to a receiver. Matching means is provided to compensate for a Q-factor of the parallel resonance for improving a reception gain over a wide range in a reception band.
摘要翻译：电感元件布置成与机动车辆上的天线元件的接地杂散电容分量并行耦合到接收器。提供匹配装置以补偿并联谐振的Q因子，以改善在接收频带中的宽范围内的接收增益。

15. 发明授权

US08981103B2 Stable crystal of 4-oxoquinoline compound 有权
标题翻译：稳定的4-氧代喹啉化合物
公开(公告)号：US08981103B2
公开(公告)日：2015-03-17
申请号：US12538694
申请日：2009-08-10
申请人： Koji Ando , Koji Matsuda , Shuji Miyake , Hideto Uehara
发明人： Koji Ando , Koji Matsuda , Shuji Miyake , Hideto Uehara
IPC分类号： C07D215/00 , C07D215/56
CPC分类号： C07D215/56
摘要： Provision of a stabilized crystal of 6-(3-chloro-2-fluorobenzyl)-1-[(S)-1-hydroxymethyl-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (compound A). A crystal of compound A, which shows a particular X-ray powder diffraction pattern of a characteristic diffraction peaks at diffraction angles 2θ(°) as measured by X-ray powder diffractometry.
摘要翻译：提供6-（3-氯-2-氟苄基）-1 - [（S）-1-羟甲基-2-甲基丙基] -7-甲氧基-4-氧代-1,4-二氢喹啉-3-酮的稳定结晶，羧酸（化合物A）。化合物A的晶体，其显示了通过X射线粉末衍射测量的衍射角2θ时的特征衍射峰的特定X射线粉末衍射图案（°）。

16. 发明授权

US08651848B2 Sizing device 有权
标题翻译：尺寸设备
公开(公告)号：US08651848B2
公开(公告)日：2014-02-18
申请号：US13075365
申请日：2011-03-30
申请人： Koji Matsuda
发明人： Koji Matsuda
IPC分类号： B29C47/90 , B29C47/88
CPC分类号： B29C47/903 , B29C47/0023 , B29C47/0028 , B29C47/0818 , B29C47/0864 , B29C47/0867 , B29C47/34 , B29C47/8835 , B29C47/884 , B29C47/8895 , B29C47/90 , B29C47/907
摘要： A sizing device is installed on a downstream side in an extrusion direction of a die. A table having two sizing unit attachment portions which are adjacent to each other in a lateral direction orthogonal to the extrusion direction. The table is provided at a device body so as to be laterally movable between a first position where one of the two sizing unit attachment portions is at a production position and the other of the two sizing unit attachment portions is at a standby position, and a second position where the other of the two sizing unit attachment portions is at the production position and the one of the two sizing unit attachment portions is at the standby position. A sizing unit for production configured to perform cooling and sizing in practice is detachably attached to one of the two sizing unit attachment portions at the production position to coincide with an extrusion line. A sizing unit for replacement is detachably attachable to the other of the two sizing unit attachment portions at the standby position.
摘要翻译：定型装置安装在模具挤出方向的下游侧。具有在与挤压方向正交的横向方向上彼此相邻的两个施胶单元附接部的台。桌子设置在装置主体处，以便在两个施胶单元附接部分中的一个处于生产位置并且两个施胶单元附接部分中的另一个处于待机位置的第一位置之间可横向移动;以及第二位置，其中两个施胶单元附接部分中的另一个处于生产位置，并且两个施胶单元安装部分中的一个处于待机位置。在实际中，构造成进行冷却和施胶的生产用尺寸单元可以在生产位置上与两个施胶单元安装部分中的一个可拆卸地连接，以与挤出生产线重合。用于更换的尺寸单元可拆卸地附接到待机位置处的两个施胶单元附接部分中的另一个。

17. 发明授权

US08634587B2 Acoustic conversion device 有权
标题翻译：声转换装置
公开(公告)号：US08634587B2
公开(公告)日：2014-01-21
申请号：US13110084
申请日：2011-05-18
申请人： Tsutomu Nagumo , Koji Matsuda , Koji Nageno , Takeshi Hara , Takahiro Suzuki , Takayuki Ishii , Kenji Hiraiwa
发明人： Tsutomu Nagumo , Koji Matsuda , Koji Nageno , Takeshi Hara , Takahiro Suzuki , Takayuki Ishii , Kenji Hiraiwa
IPC分类号： H04R1/00 , H04R9/06 , H04R11/02
CPC分类号： H04R11/02
摘要： An acoustic conversion device includes: a driving unit including a pair of magnets, a yoke, a coil, a vibrating portion which vibrates when driving current is supplied to the coil, and an armature disposed between the pair of magnets with the vibrating portion being passed through the coil; and a diaphragm unit including a holding frame having an opening, a resin film adhered to the holding frame, a diaphragm held within the holding frame, and a beam portion for propagating the vibration of the vibrating portion to the diaphragm; with the beam portion being combined with one edge side of the diaphragm, a predetermined gap being formed between the other edge of the diaphragm, and the inner face of the holding frame, a reinforcing member being provided to the predetermined gap, and the diaphragm being combined with the holding frame by the resin film and the reinforcing member.
摘要翻译：声转换装置包括：驱动单元，包括一对磁体，磁轭，线圈，当驱动电流被提供给线圈时振动的振动部分;以及设置在所述一对磁体之间的电枢，其中所述振动部分通过通过线圈; 以及膜片单元，包括具有开口的保持框架，粘附到保持框架的树脂膜，保持在保持框架内的隔膜，以及用于将振动部分的振动传播到隔膜的梁部分; 其中梁部分与隔膜的一个边缘侧结合，在隔膜的另一边缘与保持框架的内表面之间形成预定间隙，加强构件设置在预定间隙上，隔膜为通过树脂膜和加强构件与保持框架结合。

18. 发明授权

US08630439B2 Acoustic conversion device and acoustic conversion device assembly method 有权
标题翻译：声转换装置和声转换装置组装方法
公开(公告)号：US08630439B2
公开(公告)日：2014-01-14
申请号：US13104674
申请日：2011-05-10
申请人： Tsutomu Nagumo , Koji Matsuda , Koji Nageno , Takeshi Hara , Takahiro Suzuki , Takayuki Ishii , Kenji Hiraiwa
发明人： Tsutomu Nagumo , Koji Matsuda , Koji Nageno , Takeshi Hara , Takahiro Suzuki , Takayuki Ishii , Kenji Hiraiwa
IPC分类号： H04R1/02
CPC分类号： H04R11/02 , H04R31/006
摘要： An acoustic conversion device includes: a driving unit including magnets, a yoke, a coil, a vibrating portion, and an armature fixed to the yoke; a diaphragm unit including a holding frame fixed to the driving unit, with one face as a first-joint face jointed to the driving unit, and the other face as a second-joint face, a resin film adhered to the holding frame, a diaphragm held on the holding frame, and a beam portion propagating vibration from the vibrating portion to the diaphragm; and a storage unit including a case body for storing the driving unit and diaphragm unit; with the driving unit and diaphragm unit being stored in the case body, the case body being pressed against and deforming a sealing agent loaded in the second-joint face, from a side facing the second-joint face, thereby sealing each gap between the case body, cover body, and holding frame.
摘要翻译：声转换装置包括：驱动单元，包括磁体，磁轭，线圈，振动部分和固定到磁轭的电枢; 隔膜单元，其包括固定到所述驱动单元的保持框架，一个面作为连接到所述驱动单元的第一接合面，所述另一个面作为第二关节面，粘附到所述保持框架的树脂膜，隔膜保持在保持框架上的梁部分和从振动部分传播到隔膜的振动部分; 以及存储单元，包括用于存储驱动单元和隔膜单元的壳体; 驱动单元和隔膜单元被存储在壳体中时，壳体从面向第二接合面的一侧按压并使装载在第二接合面中的密封剂变形，从而将壳体身体，盖体和护框架。

19. 发明授权

US07755305B2 Charged particle beam extraction system and method 失效
标题翻译：带电粒子束提取系统及方法
公开(公告)号：US07755305B2
公开(公告)日：2010-07-13
申请号：US12129145
申请日：2008-05-29
申请人： Masumi Umezawa , Kazuo Hiramoto , Koji Matsuda
发明人： Masumi Umezawa , Kazuo Hiramoto , Koji Matsuda
IPC分类号： H05H13/04 , H05H7/10 , A61N5/10
CPC分类号： A61N5/10 , A61N2005/1074 , A61N2005/1087 , G21K1/043 , H05H7/10
摘要： A charged particle beam extraction system and method capable of shortening the irradiation time and increasing the number of patients treatable per unit time. The charged particle beam extraction system comprises a synchrotron for cyclically performing patterned operation including four steps of introducing, accelerating, extracting and decelerating an ion beam, an on/off switch for opening or closing connection between an RF knockout electrode and an RF power supply for applying RF power to the RF knockout electrode, and a timing controller for controlling on/off-timing of the on/off switch such that when extraction of the ion beam is stopped at least once during the extraction step of the synchrotron, an amount of the ion beam extracted from the synchrotron in one cycle is held substantially at a setting value.
摘要翻译：一种带电粒子束提取系统和方法，其能够缩短照射时间并增加每单位时间可治疗的患者数量。带电粒子束提取系统包括用于循环执行图案化操作的同步加速器，其包括引入，加速，提取和减速离子束的四个步骤，用于打开或关闭RF击穿电极和RF电源之间的连接的开/关开关，将RF功率施加到RF击穿电极，以及定时控制器，用于控制开/关开关的接通/断开定时，使得当在同步加速器的提取步骤期间离子束的提取停止至少一次时，在一个周期内从同步加速器提取的离子束基本保持在设定值。

20. 发明授权

US07560717B2 Particle beam irradiation apparatus, treatment planning unit, and particle beam irradiation method 有权
标题翻译：粒子束照射装置，处理计划单元和粒子束照射方法
公开(公告)号：US07560717B2
公开(公告)日：2009-07-14
申请号：US11646369
申请日：2006-12-28
申请人： Koji Matsuda , Takahide Nakayama
发明人： Koji Matsuda , Takahide Nakayama
IPC分类号： G21G4/00 , G21G5/00 , H01J5/18
CPC分类号： H05H7/10 , A61N5/1043 , A61N5/1044 , A61N2005/1087 , G21K1/08 , G21K5/04 , H05H7/04
摘要： A particle beam irradiation apparatus includes a synchrotron, two scanning electromagnets, a beam delivery apparatus for outputting an ion beam extracted from the synchrotron, and an accelerator and transport system controller, and a scanning controller. These controllers stop the output of the ion beam from the beam delivery apparatus; in a state where the output of the ion beam is stopped, change the irradiation position of the ion beam by controlling the scanning electromagnets; and after this change, control the scanning electromagnets to start the output of the ion beam from the beam delivery apparatus and to perform irradiations of the ion beam to at least one irradiation position a plurality of times based on treatment planning information.
摘要翻译：粒子束照射装置包括同步加速器，两个扫描电磁体，用于输出从同步加速器提取的离子束的射束输送装置，以及加速器和输送系统控制器以及扫描控制器。这些控制器停止来自束输送装置的离子束的输出; 在离子束的输出停止的状态下，通过控制扫描电磁体来改变离子束的照射位置; 并且在该变化之后，控制扫描电磁铁开始来自光束输送装置的离子束的输出，并且基于处理计划信息，多次对离子束进行至少一个照射位置的照射。

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