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11. 发明申请

US20080247503A1 MEASURING BLOOD VOLUME WITH C-ARM COMPUTED TOMOGRAPHY 有权
标题翻译：用C-ARM计算机血压测量血液量
公开(公告)号：US20080247503A1
公开(公告)日：2008-10-09
申请号：US12061357
申请日：2008-04-02
申请人： Guenter Lauritsch , Thomas Redel , Michael Zellerhoff
发明人： Guenter Lauritsch , Thomas Redel , Michael Zellerhoff
IPC分类号： A61B6/03
CPC分类号： A61B6/504 , A61B6/032 , A61B6/4441 , A61B6/481 , A61B6/507
摘要： A system and method of obtaining perfusion data for cerebral tissue is described. The system includes a C-arm X-ray device and a computing system configured to obtain sets of rotational projection X-ray data suitable for reconstructing 3D voxel data sets. A first data set is obtained of the patient, and then contrast material is injected into the vascular system to obtain a second 1 data set. A first voxel data set is subtracted from the second voxel data set, and the resultant data set is processed so as to segment the contrast-enhanced vasculature from the remaining data. The segmented voxels are subtracted from the resultant voxel data set, so as to yield a functional data set representing the difference between the attenuation of the tissues after administering contrast agent and the tissues prior to administering the contrast agent, without the contrast enhanced vasculature. The attenuation of the functional data set represents the perfusion or cerebral blood volume (CBV).
摘要翻译：描述了获得脑组织灌注数据的系统和方法。该系统包括C臂X射线装置和被配置为获得适于重建3D体元数据集的旋转投影X射线数据的组的计算系统。获得患者的第一数据集，然后将造影材料注入血管系统以获得第二个1数据集。从第二体素数据集中减去第一体素数据集，并且处理结果数据集，以便从剩余数据中分割对比度增强的脉管系统。从所得到的体元数据集中减去分割体素，从而产生表示施用造影剂之前的组织的衰减与施用造影剂之前的组织之间的差异的功能数据集，而没有对比度增强的脉管系统。功能数据集的衰减表示灌注或脑血容量（CBV）。

12. 发明申请

US20080123805A1 Method for x-ray image recording of a non-centric imaging area using an x-ray imaging system, and x-ray imaging system 有权
标题翻译：使用X射线成像系统的非中心成像区域的x射线图像记录方法和x射线成像系统
公开(公告)号：US20080123805A1
公开(公告)日：2008-05-29
申请号：US11901616
申请日：2007-09-18
申请人： Michael Zellerhoff
发明人： Michael Zellerhoff
IPC分类号： A61B6/03
CPC分类号： G01N23/046 , A61B6/4441 , A61B6/4458 , A61B6/466 , B25J15/0019 , G01N2223/419 , G03B42/02
摘要： There is described a method using an X-ray imaging unit, which has an arched support for the X-ray source and the X-ray detector. In the method, in a scan carried out by moving the support around an examination object a plurality of X-ray images of an area of interest are recorded using different projection angles, from which a three-dimensional image of the area of interest can be reconstructed. In this case the X-ray focus of the X-ray source is guided on a segment of a circular path of at least 180° around the examination object. In the case of a non-centric location of the area of interest, the support is rotated in such a manner prior to each of the X-ray imaging processes around an axis of rotation passing through the X-ray focus that the central ray of the X-ray beam for the X-ray imaging processes passes through the center of the area of interest.
摘要翻译：描述了使用具有用于X射线源和X射线检测器的弓形支撑的X射线成像单元的方法。在该方法中，在通过使支架围绕检查对象移动进行的扫描中，使用不同的投影角度记录感兴趣区域的多个X射线图像，感兴趣区域的三维图像可以从该投影角度重建。在这种情况下，X射线源的X射线焦点被引导到围绕检查对象的至少180°的圆形路径的段上。在感兴趣区域的非中心位置的情况下，在穿过X射线焦点的旋转轴线周围的每个X射线成像处理之前，支撑件以这样的方式旋转，即：用于X射线成像处理的X射线束通过感兴趣区域的中心。

13. 发明申请

US20080089468A1 Method for reconstructing a three-dimensional image volume and x-ray devices 有权
标题翻译：重建三维图像体积和x射线装置的方法
公开(公告)号：US20080089468A1
公开(公告)日：2008-04-17
申请号：US11897348
申请日：2007-08-30
申请人： Benno Heigl , Stefan Hoppe , Joachim Hornegger , Ernst-Peter Ruhrnschopf , Holger Scherl , Bernhard Scholz , Michael Zellerhoff
发明人： Benno Heigl , Stefan Hoppe , Joachim Hornegger , Ernst-Peter Ruhrnschopf , Holger Scherl , Bernhard Scholz , Michael Zellerhoff
IPC分类号： A61B6/03
CPC分类号： G01N23/046 , A61B6/027 , A61B6/032 , A61B6/4458 , G01N2223/419 , G01N2223/612
摘要： To enable an artifact free reconstruction even in the case of large regions of interest and with scanning paths of below 360°, provision is made for a method, with which a three-dimensional image volume is reconstructed from a number of two-dimensional projection images of a region of interest, which were recorded about the region of interest during a rotation of a recording system, comprising an x-ray source with a focal point and a detector, by calculating the gray scale values of the voxels of the image volume by back projection of the projection images, with which each two-dimensional projection images is composed in each instance from at least two individual projection images to form an extended two-dimensional projection image, with the respectively at least two individual projection images being recorded with a constant relative position between the focal point and the region of interest.
摘要翻译：为了即使在感兴趣的大区域和360度以下的扫描路径的情况下也能够实现无伪影重建，提供一种方法，利用该方法从多个二维投影图像重建三维图像体积通过计算图像体积的体素的灰度值，通过计算图像体积的体素的灰度值，记录关于记录系统旋转期间的感兴趣区域的感兴趣区域，其包括具有焦点和检测器的x射线源投影图像的背投影，每个二维投影图像在每个实例中由至少两个单独的投影图像组成，以形成扩展的二维投影图像，分别具有至少两个单独的投影图像被记录有焦点和感兴趣区域之间的常数相对位置。

14. 发明申请

US20080056438A1 Method and device for the separate three-dimensional representation of the arterial and venous vascular system using C-arm angiography systems 有权
标题翻译：使用C臂血管造影系统的动脉和静脉血管系统的单独三维表示的方法和装置
公开(公告)号：US20080056438A1
公开(公告)日：2008-03-06
申请号：US11897373
申请日：2007-08-30
申请人： Michael Zellerhoff
发明人： Michael Zellerhoff
IPC分类号： A61B6/03
CPC分类号： A61B6/504 , A61B6/4441 , A61B6/481
摘要： The invention relates to a method and a device for the separate three-dimensional representation of arteries and/or veins in a vascular system of the body by means of a C-arm biplanar system having two C-arms, which can each record a sequence of x-ray images from different projection angles during a mask or filler pass. With the filler pass, both C-arms record x-ray images, so that the x-ray images of the filler pass can be combined to form a first data record, which contains x-ray images from the arterial phase of the vascular contrasting and/or to form a second data record, which contains x-ray images from the venous phase of the vascular contrasting. This enables the arterial and venous phases to be reconstructed separately.
摘要翻译：本发明涉及一种用于通过具有两个C形臂的C臂双平面系统在身体的血管系统中分离地三维表示动脉和/或静脉的方法和装置，其可以记录一个序列在掩模或填充物通过期间，来自不同投影角度的X射线图像。利用填充通道，两个C臂记录X射线图像，使得填充通路的x射线图像可以组合以形成第一数据记录，其包含来自血管对比的动脉期的X射线图像和/或形成第二数据记录，其包含来自血管造影的静脉期的X射线图像。这使得能够分开重建动脉和静脉期。

15. 发明授权

US08755583B2 Method and apparatus for generating a functional data set of a perfused region of the human or animal body 有权
标题翻译：用于产生人或动物体的灌注区域的功能数据集的方法和装置
公开(公告)号：US08755583B2
公开(公告)日：2014-06-17
申请号：US12729269
申请日：2010-03-23
申请人： Yu Deuerling-Zheng , Thomas Redel , Michael Zellerhoff
发明人： Yu Deuerling-Zheng , Thomas Redel , Michael Zellerhoff
IPC分类号： G01N23/04 , G06K9/00 , H05G1/08
CPC分类号： A61B6/504 , A61B6/481 , A61B6/507 , A61B6/5235 , A61B2090/364
摘要： A method and apparatus for generating at least one functional data set of a perfused region of the human or animal body are proposed. A first image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a first artery supplying the region. A second image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a second artery supplying the region. A first functional data set is generated by pixel-based calculation of at least one perfusion parameter from the first image data set. A second functional data set is generated by pixel-based calculation of at least one perfusion parameter from the second image data set.
摘要翻译：提出了一种用于产生人体或动物身体的灌注区域的至少一个功能数据集的方法和装置。提供第一图像数据组，其包括在将造影剂注射到供应该区域的第一动脉之前和之后的不同时间记录的灌注区域的至少两个图像。提供第二图像数据集，其包括在将造影剂注射到供应该区域的第二动脉之前和之后的不同时间记录的灌注区域的至少两个图像。通过基于来自第一图像数据集的至少一个灌注参数的基于像素的计算来生成第一功能数据集。通过基于来自第二图像数据集的至少一个灌注参数的基于像素的计算来生成第二功能数据集。

16. 发明授权

US07899152B2 Method for the three-dimensional representation of a moving structure by a tomographic method 有权
标题翻译：通过断层摄影法对移动结构进行三维表示的方法
公开(公告)号：US07899152B2
公开(公告)日：2011-03-01
申请号：US12221938
申请日：2008-08-07
申请人： Jan Boese , Wolfgang Härer , Michael Zellerhoff
发明人： Jan Boese , Wolfgang Härer , Michael Zellerhoff
IPC分类号： A61B6/00
CPC分类号： A61B6/025 , A61B6/027 , A61B6/4441 , A61B6/466 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/507 , G06T11/006 , G06T2211/404 , G06T2211/412 , G06T2211/436
摘要： The invention relates to a method for a three-dimensional representation of a moving structure by a tomographic method, in which during one recording pass a series of projection recordings is registered by an imaging unit at different recording angles between a start position and an end position, it being possible to reconstruct three-dimensional image data from the projection recordings with the following steps: a) generation of tomosynthesis projection recordings along a tomosynthesis scanning path; b) interpolation of the data of the tomosynthesis projection recordings in accordance with an interpolation algorithm in order to generate a projection data set; c) use of a tomosynthesis reconstruction method on the projection data set in order to generate a tomosynthesis volume image; d) repetition of steps b) and c) for all times of interest, and e) display of tomosynthesis representations from the tomosynthesis volume images.
摘要翻译：本发明涉及一种用于通过断层摄影方法对运动结构进行三维表示的方法，其中在一次记录通过期间，成像单元以起始位置和结束位置之间的不同记录角度登记一系列投影记录可以通过以下步骤从投影记录重建三维图像数据：a）沿着断层合成扫描路径生成断层合成投影记录; b）根据插值算法对所述断层合成投影记录的数据进行插值，以生成投影数据集; c）在投影数据集上使用断层合成重建方法，以便产生断层合成体积图像; d）对所有感兴趣的时间重复步骤b）和c），以及e）从断层合成体积图像显示断层合成表示。

17. 发明授权

US07711083B2 Method for reconstructing a three-dimensional image volume and x-ray devices 有权
标题翻译：重建三维图像体积和x射线装置的方法
公开(公告)号：US07711083B2
公开(公告)日：2010-05-04
申请号：US11897348
申请日：2007-08-30
申请人： Benno Heigl , Stefan Hoppe , Joachim Hornegger , Ernst-Peter Rührnschopf , Holger Scherl , Bernhard Scholz , Michael Zellerhoff
发明人： Benno Heigl , Stefan Hoppe , Joachim Hornegger , Ernst-Peter Rührnschopf , Holger Scherl , Bernhard Scholz , Michael Zellerhoff
IPC分类号： A61B6/00
CPC分类号： G01N23/046 , A61B6/027 , A61B6/032 , A61B6/4458 , G01N2223/419 , G01N2223/612
摘要： To enable an artifact free reconstruction even in the case of large regions of interest and with scanning paths of below 360°, provision is made for a method, with which a three-dimensional image volume is reconstructed from a number of two-dimensional projection images of a region of interest, which were recorded about the region of interest during a rotation of a recording system, comprising an x-ray source with a focal point and a detector, by calculating the gray scale values of the voxels of the image volume by back projection of the projection images, with which each two-dimensional projection images is composed in each instance from at least two individual projection images to form an extended two-dimensional projection image, with the respectively at least two individual projection images being recorded with a constant relative position between the focal point and the region of interest.
摘要翻译：为了即使在感兴趣的大区域和360度以下的扫描路径的情况下也能够实现无伪影重建，提供一种方法，利用该方法从多个二维投影图像重建三维图像体积通过计算图像体积的体素的灰度值，通过计算图像体积的体素的灰度值，记录关于记录系统旋转期间的感兴趣区域的感兴趣区域，其包括具有焦点和检测器的x射线源投影图像的背投影，每个二维投影图像在每个实例中由至少两个单独的投影图像组成，以形成扩展的二维投影图像，分别具有至少两个单独的投影图像被记录有焦点和感兴趣区域之间的常数相对位置。

18. 发明申请

US20080031403A1 Method for providing 3D image data and system for taking x-ray images 有权
标题翻译：提供3D图像数据的方法和用于摄取X射线图像的系统
公开(公告)号：US20080031403A1
公开(公告)日：2008-02-07
申请号：US11888882
申请日：2007-08-02
申请人： Wolfgang Harer , Michael Zellerhoff
发明人： Wolfgang Harer , Michael Zellerhoff
IPC分类号： A61B6/02 , A61B6/03
CPC分类号： A61B6/02 , A61B6/4458
摘要： In a known type of tomosynthesis x-ray source and x-ray detector are linearly moved and x-rays images are taken for a large number of positions, the images being reconstructed to give a 3D image record. According to the invention x-ray source and x-ray detector are swiveled and a sequence of x-rays is subsequently taken again, x-ray source and x-ray detector again being moved in a straight line. One drawback of simple tomosynthesis with movement in a straight line is suppressed thereby, the drawback being that the quality of reconstruction is particularly poor in a certain direction.
摘要翻译：在已知类型的断层合成中，X射线源和X射线检测器被线性移动，并且对于大量的位置拍摄X射线图像，重建图像以给出3D图像记录。根据本发明，X射线源和X射线检测器被旋转，并且随后再次取得一系列X射线，x射线源和X射线检测器再次以直线移动。抑制了直线运动的简单断层合成的一个缺点在于其重要性在一定方向上特别差。

19. 发明授权

US08285014B2 Measuring blood volume with C-arm computed tomography 有权
标题翻译：用C臂计算机断层扫描测量血容量
公开(公告)号：US08285014B2
公开(公告)日：2012-10-09
申请号：US12061357
申请日：2008-04-02
申请人： Guenter Lauritsch , Thomas Redel , Michael Zellerhoff
发明人： Guenter Lauritsch , Thomas Redel , Michael Zellerhoff
IPC分类号： G06K9/00 , H05G1/64
CPC分类号： A61B6/504 , A61B6/032 , A61B6/4441 , A61B6/481 , A61B6/507
摘要： A system and method of obtaining perfusion data for cerebral tissue is described. The system includes a C-arm X-ray device and a computing system configured to obtain sets of rotational projection X-ray data suitable for reconstructing 3D voxel data sets. A first data set is obtained of the patient, and then contrast material is injected into the vascular system to obtain a second 1 data set. A first voxel data set is subtracted from the second voxel data set, and the resultant data set is processed so as to segment the contrast-enhanced vasculature from the remaining data. The segmented voxels are subtracted from the resultant voxel data set, so as to yield a functional data set representing the difference between the attenuation of the tissues after administering contrast agent and the tissues prior to administering the contrast agent, without the contrast enhanced vasculature. The attenuation of the functional data set represents the perfusion or cerebral blood volume (CBV).
摘要翻译：描述了获得脑组织灌注数据的系统和方法。该系统包括C臂X射线装置和被配置为获得适于重建3D体元数据集的旋转投影X射线数据的组的计算系统。获得患者的第一数据集，然后将造影材料注入血管系统以获得第二个1数据集。从第二体素数据集中减去第一体素数据集，并且处理结果数据集，以便从剩余数据中分割对比度增强的脉管系统。从所得到的体元数据集中减去分割体素，从而产生表示施用造影剂之前的组织的衰减与施用造影剂之前的组织之间的差异的功能数据集，而没有对比度增强的脉管系统。功能数据集的衰减表示灌注或脑血容量（CBV）。

20. 发明授权

US08126236B2 Method and device for the separate three-dimensional representation of arteries and veins in an examination object and device 有权
标题翻译：用于检查对象和装置中动脉和静脉的单独三维表示的方法和装置
公开(公告)号：US08126236B2
公开(公告)日：2012-02-28
申请号：US12283419
申请日：2008-09-11
申请人： Wolfgang Härer , Michael Zellerhoff
发明人： Wolfgang Härer , Michael Zellerhoff
IPC分类号： A61B6/03
CPC分类号： A61B6/504 , A61B6/466 , A61B6/481 , Y10S378/901
摘要： Method for three-dimensional representation of arteries and/or veins in an object by a tomography x-ray device is proposed. A mask pass with N projections at N angular positions without contrast agent is implemented. A first filler pass with M projections at M angular positions after injecting a contrast agent, where M
摘要翻译：提出了一种通过层析X射线装置对物体中动脉和/或静脉进行三维表示的方法。实现具有N个投影在N个角位置的无造影剂的掩模通过。在注射造影剂之后的M个角位置的M个投影的第一填充物通过，其中实施M

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