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    • 2. 发明申请
    • MEASURING BLOOD VOLUME WITH C-ARM COMPUTED TOMOGRAPHY
    • 用C-ARM计算机血压测量血液量
    • US20080247503A1
    • 2008-10-09
    • US12061357
    • 2008-04-02
    • Guenter LauritschThomas RedelMichael Zellerhoff
    • Guenter LauritschThomas RedelMichael Zellerhoff
    • A61B6/03
    • A61B6/504A61B6/032A61B6/4441A61B6/481A61B6/507
    • A system and method of obtaining perfusion data for cerebral tissue is described. The system includes a C-arm X-ray device and a computing system configured to obtain sets of rotational projection X-ray data suitable for reconstructing 3D voxel data sets. A first data set is obtained of the patient, and then contrast material is injected into the vascular system to obtain a second 1 data set. A first voxel data set is subtracted from the second voxel data set, and the resultant data set is processed so as to segment the contrast-enhanced vasculature from the remaining data. The segmented voxels are subtracted from the resultant voxel data set, so as to yield a functional data set representing the difference between the attenuation of the tissues after administering contrast agent and the tissues prior to administering the contrast agent, without the contrast enhanced vasculature. The attenuation of the functional data set represents the perfusion or cerebral blood volume (CBV).
    • 描述了获得脑组织灌注数据的系统和方法。 该系统包括C臂X射线装置和被配置为获得适于重建3D体元数据集的旋转投影X射线数据的组的计算系统。 获得患者的第一数据集,然后将造影材料注入血管系统以获得第二个1数据集。 从第二体素数据集中减去第一体素数据集,并且处理结果数据集,以便从剩余数据中分割对比度增强的脉管系统。 从所得到的体元数据集中减去分割体素,从而产生表示施用造影剂之前的组织的衰减与施用造影剂之前的组织之间的差异的功能数据集,而没有对比度增强的脉管系统。 功能数据集的衰减表示灌注或脑血容量(CBV)。
    • 4. 发明授权
    • Method for reconstructing a three-dimensional image of an object scanned in the context of a tomosynthesis, and apparatus for tomosynthesis
    • US06442288B1
    • 2002-08-27
    • US09207125
    • 1998-12-07
    • Wolfgang HaererGuenter LauritschMichael Zellerhoff
    • Wolfgang HaererGuenter LauritschMichael Zellerhoff
    • G06K900
    • G06T11/006G01N23/044G01N2223/419G06T2211/421G06T2211/436
    • In a method for reconstruction of a three-dimensional image of an object scanned in linear or circular fashion in the context of a tomosynthesis. The object is transirradiated with X-rays from various projection angles &phgr; for the recording of the projection images, and the radiation exiting from the object is recorded by a detector that supplies digital output image signals. The output image signals representing the projection image data are supplied to a computer for image reconstruction. In the context of the reconstruction a filter is first produced, on the basis of the following steps: A 3D transmission function Hproj(&ohgr;x,&ohgr;y,&ohgr;z) is calculated from the recording geometry for the individual projection image recording and the back-projection of the individual projection images into the 3D reconstruction image volume. By approximation, the 3D transmission function Hproj(&ohgr;x,&ohgr;y,&ohgr;z) is inverted for the determination of an inversion function Hinv(&ohgr;x,&ohgr;y,&ohgr;z). A 3D filtering function Hopt(&ohgr;x,&ohgr;y,&ohgr;z) is produced dependent on one or more desired image characteristics of the reconstruction image. A resulting 3D filtering function Hfilter(&ohgr;x,&ohgr;y,&ohgr;z) is determined by multiplication of the 3D filtering function Hopt(&ohgr;x,&ohgr;y,&ohgr;z) and the inversion function Hinv(&ohgr;x,&ohgr;y,&ohgr;z). A 2D filtering function H2Dfilter,&phgr;(&ohgr;u,&ohgr;v) is determined from the resulting 3D filtering function Hfilter(&ohgr;u,&ohgr;v &ohgr;z) by coordinate transformation of the 3D object space into the 2D projection image space of the respective individual projection images at the projection angle &phgr;. After calculating the filter, the reconstruction of the image takes place in the computer by application of the 2D filtering function H2Dfilter,&phgr;(&ohgr;u,&ohgr;v) to the associated individual projection image data, and production of the reconstruction image by back-projection of the filtered individual projection image data, into the 3D reconstruction image volume.
    • 5. 发明授权
    • Measuring blood volume with C-arm computed tomography
    • 用C臂计算机断层扫描测量血容量
    • US08285014B2
    • 2012-10-09
    • US12061357
    • 2008-04-02
    • Guenter LauritschThomas RedelMichael Zellerhoff
    • Guenter LauritschThomas RedelMichael Zellerhoff
    • G06K9/00H05G1/64
    • A61B6/504A61B6/032A61B6/4441A61B6/481A61B6/507
    • A system and method of obtaining perfusion data for cerebral tissue is described. The system includes a C-arm X-ray device and a computing system configured to obtain sets of rotational projection X-ray data suitable for reconstructing 3D voxel data sets. A first data set is obtained of the patient, and then contrast material is injected into the vascular system to obtain a second 1 data set. A first voxel data set is subtracted from the second voxel data set, and the resultant data set is processed so as to segment the contrast-enhanced vasculature from the remaining data. The segmented voxels are subtracted from the resultant voxel data set, so as to yield a functional data set representing the difference between the attenuation of the tissues after administering contrast agent and the tissues prior to administering the contrast agent, without the contrast enhanced vasculature. The attenuation of the functional data set represents the perfusion or cerebral blood volume (CBV).
    • 描述了获得脑组织灌注数据的系统和方法。 该系统包括C臂X射线装置和被配置为获得适于重建3D体元数据集的旋转投影X射线数据的组的计算系统。 获得患者的第一数据集,然后将造影材料注入血管系统以获得第二个1数据集。 从第二体素数据集中减去第一体素数据集,并且处理结果数据集,以便从剩余数据中分割对比度增强的脉管系统。 从所得到的体元数据集中减去分割体素,从而产生表示施用造影剂之前的组织的衰减与施用造影剂之前的组织之间的差异的功能数据集,而没有对比度增强的脉管系统。 功能数据集的衰减表示灌注或脑血容量(CBV)。