专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明专利

JP2015057964A 組織工学用支持体有权
标题翻译：支持组织工程
公开(公告)号：JP2015057964A
公开(公告)日：2015-03-30
申请号：JP2013192604
申请日：2013-09-18
申请人：株式会社ジーシー , Gc Corp
发明人： YAMANAKA KATSUYUKI , YAMAMOTO KATSUSHI , SAKAI YUUDAI , SHIGEMITSU YUSUKE , KANEKO TADASHI
IPC分类号： C12M3/00 , A61L27/00 , C12M1/00
摘要：【課題】多孔質構造を有するブロック状組織工学用支持体から構成され、分割せず用いることも、必要に応じて適当な大きさに容易に分割して用いることも可能な組織工学用支持体を提供することを課題とする。【解決手段】生体吸収性高分子材料から成り多孔質構造を有する複数のブロック状組織工学用支持体同士が部分的に接着されて一体化されたことを特徴とする組織工学用支持体1とする。前記複数のブロック状組織工学支持体1a同士は、それぞれの面1bで接触し、その接触面の外周及び/または内部の複数箇所が接着されて一体化されることが好ましい。【選択図】図1
摘要翻译：要解决的问题：提供组织工程的支撑，其由用于具有多孔结构的组织工程的块状支撑件组成，并且可以在不分开或任选地分成适当尺寸的情况下被使用。解决方案：用于组织工程的支撑件1 通过部分地彼此粘合两个或更多个用于由生物可吸收的聚合物材料组成的组织工程的块状支撑体并具有多孔结构。优选地，用于组织工程的两个或更多个块状形状的支撑件1a在每个表面1b上彼此接触，并且外围和/或内部接触表面上的两个或更多点被结合。

12. 发明专利

JP2015000208A 骨折部治療用部材审中-公开
标题翻译：骨折部分治疗成员
公开(公告)号：JP2015000208A
公开(公告)日：2015-01-05
申请号：JP2013126450
申请日：2013-06-17
申请人：株式会社ジーシー , Gc Corp
发明人： YAMANAKA KATSUYUKI , SAKAI YUUDAI , YAMAMOTO KATSUSHI , SHIGEMITSU YUSUKE , KANEKO TADASHI
IPC分类号： A61B17/72
CPC分类号： A61B17/863 , A61B17/686 , A61B17/742 , A61B2017/00004 , A61B2017/00933 , A61B2017/561
摘要：【課題】効率よく骨再生を可能とする骨折部治療用部材を提供する。【解決手段】骨折部を挟んで一方側の骨と他方側の骨とを連結する骨折部治療用部材(10)であって、棒状の固定部材(11)と、固定部材の外周の少なくとも一部を覆うように配置される組織再生構造体(15)と、を備え、組織再生構造体は、生体吸収性材料から構成された支持体、及び、支持体により保持された骨を再生する細胞を有する。【選択図】図1
摘要翻译：要解决的问题：提供能够有效地进行骨再生的骨折部处理构件。解决方案：将一侧的骨与另一侧的骨骼连接的骨折部处理构件（10）夹着断裂部，固定部件（11），以及组织再生结构（15），其设置成覆盖固定部件的外周的至少一部分。组织再生结构包括由生物可吸收材料构成的支撑体和用于再生由支撑体保持的骨的细胞。

13. 发明专利

JP2009240766A Bone tissue regeneration sheet and production method thereof 有权
标题翻译：骨组织再生片及其生产方法
公开(公告)号：JP2009240766A
公开(公告)日：2009-10-22
申请号：JP2009048890
申请日：2009-03-03
申请人： Gc Corp , 株式会社ジーシー
发明人： YAMANAKA KATSUYUKI , YAMAMOTO KATSUSHI , SUDA YOKO , SAKAI YUUDAI , KANEKO TADASHI
IPC分类号： A61L27/00
CPC分类号： C12N5/0655 , A61L27/18 , A61L27/3817 , A61L27/3821 , A61L27/3834 , A61L27/3847 , A61L27/3895 , A61L27/58 , A61L2430/02 , C12N2500/84 , C12N2506/1353 , C12N2533/40
摘要： PROBLEM TO BE SOLVED: To provide a bone tissue regeneration sheet having a cortical bone tissue layer of 200 μm or more in thickness.
SOLUTION: This bone tissue regeneration sheet is produced by seeding chondroblast or stem cells for differentiating to chondrocyte on one side of a sheet-like porous body composed of bioabsorbable synthetic polymer, taking the seeded porous body into a culture medium, applying acceleration of 100 to 1000 G to the culture medium for a predetermined time so as to aggregate the chondroblast or the stem cells for differentiating to chondrocyte, culturing the aggregated cells in a culture medium not containing serum but containing one or two or more kinds selected from ascorbic acid, an ascorbic acid derivative, and dexamethasone without applying acceleration to form a chondrocyte layer having a thickness of 200 μm or more, and culturing the chondrocyte layer in a culture medium containing serum and endochondrally ossifying it to form the cortical bone tissue layer of 200 μm in thickness.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：待解决的问题：提供具有厚度为200μm以上的皮质骨组织层的骨组织再生片。解决方案：通过将成软骨细胞或干细胞接种到由生物可吸收的合成聚合物组成的片状多孔体的一侧上，将软骨细胞或干细胞分化成软骨细胞，将接种的多孔体置于培养基中，施加加速度将100〜1000G的培养基保持在规定时间，使成软骨细胞或干细胞聚集成软骨细胞，将培养的细胞培养在不含血清但含有选自抗坏血酸中的一种或两种以上的血清酸，抗坏血酸衍生物和地塞米松，而不加速地形成厚度为200μm以上的软骨细胞层，并且在含有血清的培养基中培养软骨细胞层并进行骨内骨化以形成200皮质骨组织层厚度。版权所有（C）2010，JPO＆INPIT

14. 发明专利

JP2011062417A Bioabsorbable member 审中-公开
标题翻译：可生物成员
公开(公告)号：JP2011062417A
公开(公告)日：2011-03-31
申请号：JP2009217122
申请日：2009-09-18
申请人： Gc Corp , 株式会社ジーシー
发明人： KANEKO TADASHI , TAKAGI TAKAMITSU , FUJII NAOTO
IPC分类号： A61L27/00 , A61B17/58 , A61C8/00 , A61L31/00
摘要： PROBLEM TO BE SOLVED: To provide a bioabsorbable member which needs no re-operation after treatment and secures enough strength to be used at a part which is relatively hard and tough. SOLUTION: The bioabsorbable member is obtained by mixing a fibrous bioabsorbable magnesium alloy with bioabsorbable polymers. The fibrous biological absorptive magnesium alloy is a magnesium alloy of Mg-Cg type, Mg-Zn type, or Mg-Al type, and preferably is 10 μm to 5 mm in length and 1 μm to 1 mm in thickness. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供一种生物吸收性构件，其在处理后不需要再次操作，并且确保足够的强度用于相对硬和坚韧的部分。解决方案：通过将纤维状生物吸收性镁合金与生物可吸收聚合物混合而获得生物可吸收构件。纤维状生物吸收性镁合金是Mg-Cg型，Mg-Zn型或Mg-Al型的镁合金，优选长度为10μm〜5mm，厚度为1μm〜1mm。版权所有（C）2011，JPO＆INPIT

15. 发明专利

JP2011062356A Bioabsorbable membrane for guided tissue regeneration and manufacturing method of the same 审中-公开
标题翻译：用于指导组织再生的生物可溶性膜及其制造方法
公开(公告)号：JP2011062356A
公开(公告)日：2011-03-31
申请号：JP2009215934
申请日：2009-09-17
申请人： Gc Corp , 株式会社ジーシー
发明人： YAMANAKA KATSUYUKI , YAMAMOTO KATSUSHI , SAKAI YUUDAI , KANEKO TADASHI
IPC分类号： A61L27/00
摘要： PROBLEM TO BE SOLVED: To provide a bioabsorbable membrane for guided tissue regeneration which is bioabsorbable like a conventional bioabsorbable membrane for guided tissue regeneration but is not torn at a part where a thread is sewn even when a thread is used, and is used for securing a space where tissues, such as periodontal tissues or bone tissues, start regenerating in a dental medical field or the like.
SOLUTION: In the bioabsorbable membrane for guided tissue regeneration 1 for giving a space for regenerating a tissue to guide the tissue to the space, a reinforcement portion 3 which does not have a hole at a prescribed part of one or both side of the membrane including porous portions 2 is formed. In order to manufacture the bioabsorbable membrane for guided tissue regeneration 1, solution solving bioabsorbable high polymers is poured into a mold, the solution is freeze-dried, and evaporated to manufacture a membrane including the porous portions 2, prescribed parts of the membrane including the porous portions 2 is heat-melted from one or both side to form the reinforcement portion 3 which does not have a hole at a prescribed part on the membrane surface including the porous portions 2.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供用于引导组织再生的生物可吸收膜，其是生物可吸收的，如常规生物可吸收膜，用于引导组织再生，但即使在使用线时也不会在缝合线的部分处被撕裂，并且是用于确保诸如牙周组织或骨组织的组织在牙科医疗领域等中开始再生的空间。解决方案：在用于引导组织再生的生物可吸收膜1中，用于给予组织再生以将组织引导到空间的空间，在第一或第二侧的一侧或两侧的规定部分不具有孔的加强部3 形成包括多孔部分2的膜。为了制造用于引导组织再生的生物可吸收膜1，将解决生物可吸收性高聚物的溶液倒入模具中，将溶液冷冻干燥并蒸发以制造包括多孔部分2的膜，包括多孔部分2从一侧或两侧加热熔化，以形成在包括多孔部分2的膜表面上的规定部分处不具有孔的加强部3。（C）2011，JPO＆INPIT

16. 发明专利

JP2009291304A Bone graft substitute 审中-公开
标题翻译：骨髓替代品
公开(公告)号：JP2009291304A
公开(公告)日：2009-12-17
申请号：JP2008145820
申请日：2008-06-03
申请人： Gc Corp , 株式会社ジーシー
发明人： YAMAMOTO KATSUSHI , YAMANAKA KATSUYUKI , SAKAI YUUDAI , SUDA YOKO , KANEKO TADASHI
IPC分类号： A61L27/00 , A61C8/00 , A61F2/28
CPC分类号： A61L27/12 , A61L27/227 , A61L27/54 , A61L2300/414 , A61L2430/02
摘要： PROBLEM TO BE SOLVED: To provide a bone graft substitute having an appropriate absorption period in a living body and high osteoconductivity. SOLUTION: This bone graft substitute contains a carbonate apatite and an osteoinductive factor. The osteoinductive factor is preferably at least one selected from a group including BMP (a bone morphogenetic factor), GDF (a growth differentiation factor), TGF-β (a transformation growth factor), FGF (a fibroblast growth factor), IGF (an insulin-like growth factor), PDGF (a platelet-derived growth factor), BDNF (a brain-derived nerve growth factor), and NGF (a nerve growth factor), and the bone graft substitute has open pores, preferably having a diameter of 50 to 1,000 μm and/or a diameter of 5 μm or less, with porosity of 20 to 80%. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供在生物体中具有适当吸收期的骨移植物替代物和高的骨传导性。解决方案：这种骨移植物替代物含有碳酸盐磷灰石和骨诱导因子。骨诱导因子优选为选自BMP（骨形态发生因子），GDF（生长分化因子），TGF-β（转化生长因子），FGF（成纤维细胞生长因子），IGF（an 胰岛素样生长因子），PDGF（血小板衍生生长因子），BDNF（脑源性神经生长因子）和NGF（神经生长因子），骨移植物替代物具有开放孔，优选具有直径为50〜1000μm，和/或直径为5μm以下，孔隙率为20〜80％。版权所有（C）2010，JPO＆INPIT

17. 发明专利

JP2007289634A Bioabsorbable tube and its manufacturing method 审中-公开
标题翻译：可生物管及其制造方法
公开(公告)号：JP2007289634A
公开(公告)日：2007-11-08
申请号：JP2006244528
申请日：2006-09-08
申请人： Gc Corp , 株式会社ジーシー
发明人： YAMAMOTO KATSUSHI , YAMANAKA KATSUYUKI , SUDA YOKO , KANEKO TADASHI
IPC分类号： A61L27/00
CPC分类号： A61B17/1128 , A61B2017/00004 , A61L27/18 , A61L27/50 , A61L27/58 , C08L67/04
摘要： PROBLEM TO BE SOLVED: To provide a bioabsorbable tube and its manufacturing method low in costs and ready to complete a set of multiple tubes differing in thickness, inner diameter and outer configuration, in comparison with conventional bioabsorbable tubes. SOLUTION: The manufacturing method for the bioabsorbable tube is that a bioabsorbable polymer material sheet produced by drying up a solvent of a solution of a bioabsorbable polymer is wound into a tubular shape, and then at lease doubled areas near the tubular sheet's outer peripheral side end edges are fused or welded together into a tube, or otherwise that the bioabsorbable polymer material sheet produced by freeze-drying up the solvent of the solution of the bioabsorbable polymer is wound into a tubular shape, and then it is further wound by another bioabsorbable polymer material sheet produced by non-freeze-drying up the solvent of the solution of the bioabsorbable polymer into a tubular shape, followed by fusing or welding together at least doubled areas near the outer peripheral side end edges of the outside bioabsorbable polymer material sheet, thus forming a double-layer bioabsorbable tube. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：与传统的生物可吸收管相比，提供低成本的生物可吸收管及其制造方法，并准备完成一组不同厚度，内径和外部构型的多个管。生物可吸收管的制造方法是通过将生物可吸收性聚合物的溶液的溶剂干燥而生成的生物体吸收性聚合物材料片卷绕成管状，然后在管状片材的外部附近的至少两倍的区域外周侧端缘熔接或焊接在一起成管，否则通过将生物可吸收性聚合物溶液的溶剂冷冻干燥而制造的生物可吸收聚合物材料片被卷绕成管状，然后进一步被另一种生物可吸收聚合物材料片，其通过将生物可吸收聚合物溶液的溶剂冷冻干燥成管状形状，然后将外部生物可吸收性聚合物材料的外周侧端缘附近的至少两倍的区域熔合或焊接在一起从而形成双层生物可吸收管。版权所有（C）2008，JPO＆INPIT

18. 发明专利

JP2006263184A Bone cement injection and filling method and leakage prevention bag for injecting and filling bone cement 审中-公开
标题翻译：骨水泥注射和填充方法和用于注射和填充骨水泥的防漏包
公开(公告)号：JP2006263184A
公开(公告)日：2006-10-05
申请号：JP2005086225
申请日：2005-03-24
申请人： Gc Corp , Nippon Sigmax Kk , 日本シグマックス株式会社 , 株式会社ジーシー
发明人： KANEKO TADASHI , YAMAMOTO KATSUSHI , TAKAHASHI MASARU
IPC分类号： A61B17/56 , A61F2/28 , A61L27/00
CPC分类号： A61B17/7097 , A61B2017/00004 , A61F2/44 , A61F2/441 , A61F2002/30062 , A61F2002/30583 , A61F2210/0004 , A61F2210/0085
摘要： PROBLEM TO BE SOLVED: To provide a novel bone cement injection and filling method and a leakage prevention bag for injecting and filling bone cement used therefor without any danger of causing complications such as neuropathy and pulmonary emboli caused by leakage of the bone cement from a crack and fracture part of vertebral body to the outside of the vertebral body when filling the bone cement for the percutaneous correction of the vertebral body, even if developing no leakage when the bone cement is acrylic-based bone cement, eliminating harmfulness to the living body caused by leakage of monomer and unhardened components, or when it is calcium phosphate bone cement, eliminating imcompletion of the hardening and lowering of the strength of the hardening body caused by contact between the blood and body fluid. SOLUTION: This leakage prevention bag 1 for injecting and filling bone cement which is constituted of bioabsorbable material with a molecular weight of 5,000-500,000 and formed of a bag body with a thickness of 10-800 μm, and whose inlet 1a for injecting the bone cement is attached to an injection tube 2, is inserted into a cavity formed in the vertebral body to be treated, and the bone cement is injected into the leakage prevention bag for injecting and filling the bone cement through the tube. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种新颖的骨水泥注射和填充方法以及用于注射和填充所使用的骨水泥的防漏袋，而不会引起由骨水泥渗漏引起的神经病变和肺栓塞等并发症的危险即使在骨水泥是丙烯酸类骨水泥的情况下，即使不发生渗漏，填充骨水泥用于椎体经皮矫正时，从椎体的裂缝和骨折部分到椎体的外侧，消除对骨质疏松的危害由于单体和未硬化组分的渗漏引起的活体，或者当它是磷酸钙骨水泥时，消除了由血液和体液之间的接触引起的硬化体硬化和降低的强度。解决方案：用于注射和填充骨水泥的防漏袋1，其由分子量为5,000-500,000的生物可吸收材料构成，并且由厚度为10-800μm的袋体形成，并且其入口1a用于将注射骨粘固剂注射到注射管2上，插入形成在待治疗的椎体中的腔中，并将骨粘固剂注射到防渗漏袋中，以通过管注射和填充骨水泥。版权所有（C）2007，JPO＆INPIT

19. 发明专利

JP2006034485A Bioabsorptive granular porous bone filling material and manufacturing method therefor 有权
标题翻译：生物颗粒多孔骨填充材料及其制造方法
公开(公告)号：JP2006034485A
公开(公告)日：2006-02-09
申请号：JP2004216887
申请日：2004-07-26
申请人： Gc Corp , 株式会社ジーシー
发明人： YAMAMOTO KATSUSHI , YAMANAKA KATSUYUKI , SUDA YOKO , KANEKO TADASHI
IPC分类号： A61L27/00 , A61B17/56 , A61K6/00
CPC分类号： A61L27/58 , A61L27/18 , A61L27/56 , A61L2430/02 , C08L67/04
摘要： PROBLEM TO BE SOLVED: To provide a granular porous bone filling material made of a bioabsorptive polymer body having a particle diameter of 100-3000 μm which has a small hole structure having a hole diameter of 5-50 μm used for filling a defective section after removing a lesion due to bone tumor, osteomyelitis, or the like, or a defective section after autologous bone transplanting, reinforcement, filling or the like of the jaw bone at the time of embedding a dental implant, and a manufacturing method therefor.
SOLUTION: The polymer body having the small hole structure with the hole diameter of 5-50 μm containing a particulate material is produced by mixing the particulate material with the particle diameter of 100-2000 μm which does not dissolve in an organic solvent and dissolves in a liquid which does not dissolve the bioabsorptive polymer into a solution in which the bioabsorptive polymer is dissolved in the organic solvent, and removing the organic solvent by drying after freezing. The bioabsorptive granular porous bone filling material with the particle diameter of 100-3000 μm is manufactured by sifting through a sieve after pulverizing the polymer body and removing the particulate material by dissolving it in the liquid which does not dissolve the bioabsorptive polymer.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：待解决的问题：提供一种由具有100-3000μm的生物吸收性聚合物体制成的颗粒状多孔骨填充材料，其具有孔径为5-50μm的小孔结构，用于填充在植入牙植入物时，由于骨肿瘤，骨髓炎等引起的病变，或自体骨移植，加固，填充等后的瑕疵骨缺损部分及其制造方法，。解决方案：通过将不溶于有机溶剂的粒径为100-2000μm的颗粒材料混合制成具有含有颗粒材料的孔直径为5-50μm的小孔结构的聚合物体并且将不溶解生物吸收性聚合物的液体溶解在生物吸收性聚合物溶解于有机溶剂中的溶液中，冷冻后通过干燥除去有机溶剂。粒径为100-3000μm的生物吸收性粒状多孔骨填充材料是在粉碎聚合物体之后筛选筛子，并通过将其溶解在不溶解生物吸收性聚合物的液体中除去颗粒物质而制造的。版权所有（C）2006，JPO＆NCIPI

20. 发明专利

JP2005270371A Implant made of titanium or titanium alloy and its surface treating method 审中-公开
标题翻译：钛或钛合金的植入物及其表面处理方法
公开(公告)号：JP2005270371A
公开(公告)日：2005-10-06
申请号：JP2004088551
申请日：2004-03-25
申请人： Gc Corp , 株式会社ジーシー
发明人： KUBOKI TAKUO , MAEKAWA KENJI , YOSHIDA YASUHIRO , MINE ATSUSHI , FUJISAWA TAKUO , SUZUKI KAZUTOMI , VAN MIIRUBEEKU BARTH , KANEKO TADASHI
IPC分类号： A61C8/00 , A61F2/00 , A61F2/30 , A61L27/06 , A61L27/36
CPC分类号： A61L27/227 , A61L27/06 , A61L27/54
摘要： PROBLEM TO BE SOLVED: To provide an implant made of titanium or a titanium alloy whose surface is modified such that synostosis is obtained easily and surely compared to the conventional surface modification of the implant made of the titanium or the titanium alloy for which treatment is complicated and instable, and its surface treating method. SOLUTION: The implant surface made of the titanium or the titanium alloy is treated with a basic fibroblast growth factor (bFGF) solution whose concentration is 1-500ng/ml after treating the implant surface made of the titanium or the titanium alloy with a polyphosphoric acid solution whose concentration is 0.05-70 wt.%, or the implant surface made of the titanium or the titanium alloy is treated with the solution in which the concentration of the polyphosphoric acid is 0.05-70 wt.% and the concentration of the basic fibroblast growth factor (bFGF) is 1-500ng/ml, thereby the implant made of the titanium or the titanium alloy whose surface is treated by the polyphosphoric acid and the basic fibroblast growth factor (bFGF) is attained. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：为了提供由钛或钛合金制成的植入物，其表面被改性，使得与由钛或钛合金制成的植入物的常规表面改性相比，容易且可靠地获得了合并症，治疗复杂而不稳定，其表面处理方法。解决方案：用钛或钛合金制成的植入物表面用碱性成纤维细胞生长因子（bFGF）溶液处理，其浓度为1-500ng / ml，在用钛或钛合金制成的植入物表面处理后，浓度为0.05-70重量％的多磷酸溶液，或由钛或钛合金制成的植入物表面，其中多磷酸的浓度为0.05-70重量％，浓度为碱性成纤维细胞生长因子（bFGF）为1-500ng / ml，从而获得由表面经多磷酸和碱性成纤维细胞生长因子（bFGF）处理的钛或钛合金制成的植入物。版权所有（C）2006，JPO＆NCIPI

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式