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11. 发明授权

US06594652B1 Electronic discussion system for exchanging information among users creating opinion indexes in accordance with content of each options 失效
标题翻译：电子讨论系统，用于根据每个选项的内容创建意见索引的用户之间交换信息
公开(公告)号：US06594652B1
公开(公告)日：2003-07-15
申请号：US09487475
申请日：2000-01-19
申请人： Yoshiaki Sunaga , Atsushi Komatsuzawa , Tetsuji Ohno , Noriyuki Takahashi
发明人： Yoshiaki Sunaga , Atsushi Komatsuzawa , Tetsuji Ohno , Noriyuki Takahashi
IPC分类号： G06F1730
CPC分类号： G06Q10/107 , Y10S707/99932 , Y10S707/99933 , Y10S707/99934 , Y10S707/99937 , Y10S707/99939 , Y10S707/99943 , Y10S707/99945
摘要： An electronic discussion system including discussion terminals for writing and managing opinion information and clients for accessing the discussion terminals through a network. The electronic discussion system comprises a discussion apparatus for storing contents of input opinions so as to have correspondence relationships with discussion topics to which the contents pertain, contents of opinions having correspondence relationships with discussion topics in which registered users participate further having correspondence relationships with user divisions corresponding to the registered users; a participated discussion reading (client) terminal responsive to an operation instruction from a registered user, for referring to and displaying contents of opinions stored in the discussion server and having a corresponding relationship with a user division corresponding to the registered user; and a non-participated discussion reading (client) terminal responsive to an operation instruction from a user other than the registered users, for inputting an instruction for selecting a discussion topic, and obtaining and displaying contents of opinions stored in the discussion apparatus and having a correspondence relationship with the selected discussion topic.
摘要翻译：一种电子讨论系统，包括用于写入和管理意见信息的讨论终端和通过网络访问讨论终端的客户端。该电子讨论系统包括一个讨论装置，用于存储输入意见的内容，以便与内容所涉及的讨论话题具有对应关系，具有与注册用户参与的讨论主题具有对应关系的意见内容与进一步具有用户分区的对应关系对应注册用户; 响应于来自注册用户的操作指令的参与讨论阅读（客户端）终端，用于参考并显示存储在讨论服务器中并且与对应于注册用户的用户分区具有对应关系的内容; 以及响应于来自注册用户以外的用户的操作指令的未参与讨论阅读（客户端）终端，用于输入选择讨论主题的指令，以及获取和显示存储在讨论装置中的意见内容，并具有与所选讨论话题的对应关系。

12. 发明授权

US06094675A Electronic discussion system for exchanging information among users 失效
标题翻译：用户交换信息的电子讨论系统
公开(公告)号：US06094675A
公开(公告)日：2000-07-25
申请号：US904552
申请日：1997-08-04
申请人： Yoshiaki Sunaga , Atsushi Komatsuzawa , Tetsuji Ohno , Noriyuki Takahashi
发明人： Yoshiaki Sunaga , Atsushi Komatsuzawa , Tetsuji Ohno , Noriyuki Takahashi
IPC分类号： G06F15/00 , G06F13/00 , G06Q10/10 , G06Q30/06 , G06Q50/00 , G06Q50/30 , G06Q50/32 , H04M3/56 , H04N7/15 , G06F17/30
CPC分类号： G06Q10/107 , Y10S707/99932 , Y10S707/99933 , Y10S707/99934 , Y10S707/99937 , Y10S707/99939 , Y10S707/99943 , Y10S707/99945
摘要： An electronic discussion system of the client/server structure for an electronic exchange of messages which are presented by a plurality of users and shown on a display of a client computer, wherein the servers comprise at least one storage server for holding detailed contents of respective pieces of opinion information, and at least one discussion server for holding opinion indexes showing the storage locations of opinion contents of respective pieces of opinion information, wherein the clients comprise an opinion writing client for transferring and writing the opinion index created from a newly presented piece of opinion information and the opinion content into the discussion server and the storage server, and a reading client for referring to opinion indexes and opinion contents recorded and managed in the discussion server and the storage server.
摘要翻译：一种用于电子交换消息的客户端/服务器结构的电子讨论系统，其由多个用户呈现并显示在客户端计算机的显示器上，其中，所述服务器包括用于保存各个部分的详细内容的至少一个存储服务器以及至少一个讨论服务器，用于举行表示各个意见信息的意见内容的存储位置的意见索引，其中，客户包括用于传送和写入由新提出的意见信息创建的意见索引的意见书写客户端意见信息和意见内容进入讨论服务器和存储服务器，以及阅读客户端，用于参考在讨论服务器和存储服务器中记录和管理的意见指标和意见内容。

13. 发明授权

US07276532B2 Remedies for vesical hyperactivity 失效
标题翻译：用于膀胱活动过度的补救措施
公开(公告)号：US07276532B2
公开(公告)日：2007-10-02
申请号：US10472143
申请日：2002-03-29
申请人： Tsuyoshi Yamagata , Kaoru Atsuki , Tetsuji Ohno , Shiro Shirakura , Akira Karasawa
发明人： Tsuyoshi Yamagata , Kaoru Atsuki , Tetsuji Ohno , Shiro Shirakura , Akira Karasawa
IPC分类号： A61K31/38
CPC分类号： C07D495/04 , A61K31/55 , C07D337/12
摘要： The present invention provides a therapeutic agent for overactive bladder comprising, as an active ingredient, a tricyclic compound represented by formula (I): [wherein R1 represents a hydrogen atom, substituted or unsubstituted lower alkyl, and the like; X1—X2—X3 represents CR5═CR6—CR7═CR8, CR5═CR6—S, and the like; Y represents —CH2S—, —SOCH2—, and the like; and R2 represents a hydrogen atom, and the like] or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明提供一种活性过氧化物的治疗剂，其包含作为活性成分的由式（I）表示的三环化合物：其中R 1表示氢原子，取代或未取代的低级烷基，和类似; X 1 - 2 - - - - - - - - - - - - - - - - - - （3） CR 7 -CR 8，CR 5 -CR 6 -S等; Y表示-CH 2 -S-，-SOCH 2 - 等; 和R 2表示氢原子等]或其药学上可接受的盐。

14. 发明申请

US20070137359A1 Speed changing operation apparatus for vehicle 审中-公开
标题翻译：车辆变速操作装置
公开(公告)号：US20070137359A1
公开(公告)日：2007-06-21
申请号：US11529093
申请日：2006-09-28
申请人： Tetsuji Ohno , Masayuki Shinmura
发明人： Tetsuji Ohno , Masayuki Shinmura
IPC分类号： F16H59/04 , G05G1/10
CPC分类号： F16H59/0278 , Y10T74/2014 , Y10T74/20732
摘要： A lever assembly, which can be used as a speed changing apparatus for vehicle, can include an operating lever shaft. The operating lever shaft can be pivotally supported on a speed changing operation unit. An operating knob can be formed with a mounting bore for receiving a top end of the operating lever shaft and can also be adapted to be mounted on the top end of the operating lever shaft for carrying out a speed changing operation of a transmission of vehicle by pivoting the operating lever shaft. An engagement member can have a cylindrical configuration of substantially same inner circumferential configuration as an outer circumferential configuration of the operating lever shaft. The engagement member can be adapted to be received and secured within the mounting bore of the operating knob and can have nails that are elastically deformable by the operating lever shaft and engaged therewith when the operating lever shaft is inserted through the engagement member.
摘要翻译：可用作车辆变速装置的杠杆组件可包括操作杆轴。操作杆轴可以枢转地支撑在变速操作单元上。操作旋钮可以形成有用于接收操作杆轴的顶端的安装孔，并且还可以适于安装在操作杆轴的顶端上，用于通过以下方式执行车辆变速器的变速操作枢转操作杆轴。接合构件可以具有与操作杆轴的外周构造基本相同的内周构造的圆柱形构造。接合构件可以适于被接收并固定在操作旋钮的安装孔内，并且可以具有当操作杆轴插入通过接合构件时由操作杆轴可弹性变形并与其接合的钉子。

15. 发明申请

US20060276531A1 Agent for the treatment of bladder irritative symptoms accompanied by benign prostatic hyperplasia 审中-公开
标题翻译：代理治疗膀胱刺激症状伴有良性前列腺增生
公开(公告)号：US20060276531A1
公开(公告)日：2006-12-07
申请号：US11503067
申请日：2006-08-14
申请人： Tsuyoshi Yamagata , Kaoru Atsuki , Tetsuji Ohno , Shiro Shirakura , Akira Karasawa , William de Groat , Naoki Yoshimura , Adrian Sculptoreanu
发明人： Tsuyoshi Yamagata , Kaoru Atsuki , Tetsuji Ohno , Shiro Shirakura , Akira Karasawa , William de Groat , Naoki Yoshimura , Adrian Sculptoreanu
IPC分类号： A61K31/381
CPC分类号： A61K31/55 , A61K31/38 , A61K31/44
摘要： The present invention provides an agent for the treatment of bladder irritative symptoms accompanied by benign prostatic hyperplasia, comprising, as an active ingredient, a compound having a slowly-inactivating A-type K+ channel opening activity or a pharmaceutically acceptable salt thereof, and a method for screening agents for the treatment of bladder irritative symptoms accompanied by benign prostatic hyperplasia, comprising measuring a slowly-inactivating A-type K+ channel opening activity as an index.
摘要翻译：本发明提供了一种用于治疗伴有良性前列腺增生的膀胱刺激症状的药剂，其包含作为活性成分的具有缓慢失活的A型K + / O通道开放活性的化合物或以及用于治疗伴有良性前列腺增生的膀胱刺激症状的筛选剂的方法，包括测量缓慢失活的A型K +通道开放活性作为指标。

16. 发明授权

US5063227A Quinazoline-substituted pyridazinone derivatives having cardiotonic activity 失效
标题翻译：具有心脏活性的喹唑啉取代的吡啶酮衍生物
公开(公告)号：US5063227A
公开(公告)日：1991-11-05
申请号：US462914
申请日：1990-01-11
申请人： Yuji Nomoto , Haruki Takai , Tetsuji Ohno , Kazuhiro Kubo
发明人： Yuji Nomoto , Haruki Takai , Tetsuji Ohno , Kazuhiro Kubo
IPC分类号： C07D401/14 , C07D403/04 , C07D487/04
CPC分类号： C07D401/14 , C07D403/04 , C07D487/04
摘要： Compounds of the formula ##STR1## wherein R.sub.3 is H or alkyl, Q.sub.1 and Q.sub.2 are independently hydrogen, alkyl, hydroxyl, alkoxyl, amino, mono or di alkylamino, nitro or halo or pharmaceutically acceptable salts are useful as cardiotonics.

17. 发明申请

US20110105486A1 THIAZOLE DERIVATIVES 有权
标题翻译：噻唑衍生物
公开(公告)号：US20110105486A1
公开(公告)日：2011-05-05
申请号：US12960937
申请日：2010-12-06
申请人： Takao Nakajima , Masamori Sugawara , Shin-ichi Uchida , Tetsuji Ohno , Yuji Nomoto , Noriaki Uesaka , Yoshisuke Nakasato
发明人： Takao Nakajima , Masamori Sugawara , Shin-ichi Uchida , Tetsuji Ohno , Yuji Nomoto , Noriaki Uesaka , Yoshisuke Nakasato
IPC分类号： A61K31/541 , C07D277/38 , C07D417/14 , C07D401/14 , C07D213/89 , C07D413/14 , C07D279/12 , A61K31/426 , A61K31/4439 , A61K31/454 , A61K31/5377 , A61P25/28 , A61P25/00 , A61P3/10 , A61P25/12 , A61P25/24
CPC分类号： C07D417/06 , A61K31/427 , A61K31/438 , A61K31/4439 , A61K31/444 , A61K31/454 , A61K31/4725 , A61K31/496 , A61K31/497 , A61K31/4985 , A61K31/501 , A61K31/506 , A61K31/5383 , A61K31/541 , A61K31/542 , A61K31/551 , A61K31/553 , A61K31/695 , C07D417/04 , C07D417/14 , C07D491/048 , C07D491/10 , C07D498/04 , C07D513/04
摘要： Wherein n is an integer of from 0 to 3; R1A is a 5-membered aromatic heterocyclic group containing at least one oxygen atom; R2A is —COR8 (wherein R8 is aryl); R3A is hydrogen or lower alkyl; and R12 represents cycloalkyl, aryl, aralkyl, alicyclic heterocyclic group, aromatic heterocyclic group, alicyclic hetocyclic-alkyl, or aromatic heterocyclic-alkyl, and R1A, R2A, R3A and R12 are individually optionally substituted.
摘要翻译：其中n为0至3的整数; R1A是含有至少一个氧原子的5元芳族杂环基; R2A是-COR8（其中R8是芳基）; R3A是氢或低级烷基; R 12表示环烷基，芳基，芳烷基，脂环族杂环基，芳香族杂环基，脂环族环状烷基或芳香族杂环烷基，R1A，R2A，R3A，R12分别任意取代。

18. 发明申请

US20100256361A1 THIAZOLE DERIVATIVES 有权
标题翻译：噻唑衍生物
公开(公告)号：US20100256361A1
公开(公告)日：2010-10-07
申请号：US12766986
申请日：2010-04-26
申请人： Takao Nakajima , Masamori Sugawara , Shin-ichi Uchida , Tetsuji Ohno , Yuji Nomoto , Noriaki Uesaka , Yoshisuke Nakasato
发明人： Takao Nakajima , Masamori Sugawara , Shin-ichi Uchida , Tetsuji Ohno , Yuji Nomoto , Noriaki Uesaka , Yoshisuke Nakasato
IPC分类号： C07D417/14 , C07D413/14 , C07D498/04
CPC分类号： C07D417/06 , A61K31/427 , A61K31/438 , A61K31/4439 , A61K31/444 , A61K31/454 , A61K31/4725 , A61K31/496 , A61K31/497 , A61K31/4985 , A61K31/501 , A61K31/506 , A61K31/5383 , A61K31/541 , A61K31/542 , A61K31/551 , A61K31/553 , A61K31/695 , C07D417/04 , C07D417/14 , C07D491/048 , C07D491/10 , C07D498/04 , C07D513/04
摘要： (Wherein n is an integer of from 0 to 3; R1 is substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, a substituted or unsubstituted alicyclic heterocyclic group, or a substituted or unsubstituted aromatic heterocyclic group; R2 is halogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl, a substituted or unsubstituted alicyclic heterocyclic group, a substituted or unsubstituted aromatic heterocyclic group, —COR8, or the like; R3 and R4 may be the same or different, and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted aralkyl, —COR12, or the like)For example, provided are adenosine A2A receptor antagonists comprising, as the active ingredient, a thiazole derivative represented by a general formula (I), or a pharmaceutically acceptable salt thereof, and the like.
摘要翻译：（其中n为0〜3的整数; R 1为取代或未取代的环烷基，取代或未取代的芳基，取代或未取代的脂环族杂环基或取代或未取代的芳香族杂环基; R2为卤素，取代或未取代的低级烷基取代或未取代的芳基，取代或未取代的脂环族杂环基，取代或未取代的芳族杂环基，-COR 8等; R 3和R 4可以相同或不同，表示氢原子，取代或未取代的低级烷基，取代或未取代的芳烷基，-COR 12等）例如，提供的是腺苷A 2A受体拮抗剂，其包含作为活性成分的由通式（I）表示的噻唑衍生物或其药学上可接受的盐，以及类似。

19. 发明授权

US07122173B2 Agent for the treatment of bladder irritative symptoms accompanied by benign prostatic hyperplasia 失效
公开(公告)号：US07122173B2
公开(公告)日：2006-10-17
申请号：US10473348
申请日：2002-03-29
申请人： Tsuyoshi Yamagata , Kaoru Atsuki , Tetsuji Ohno , Shiro Shirakura , Akira Karasawa , William C. de Groat , Naoki Yoshimura , Adrian Sculptoreanu
发明人： Tsuyoshi Yamagata , Kaoru Atsuki , Tetsuji Ohno , Shiro Shirakura , Akira Karasawa , William C. de Groat , Naoki Yoshimura , Adrian Sculptoreanu
IPC分类号： A61K10/00 , A61K49/00
CPC分类号： A61K31/55 , A61K31/38 , A61K31/44
摘要： The present invention provides an agent for the treatment of bladder irritative symptoms accompanied by benign prostatic hyperplasia, comprising, as an active ingredient, a compound having a slowly-inactivating A-type K+ channel opening activity or a pharmaceutically acceptable salt thereof, and a method for screening agents for the treatment of bladder irritative symptoms accompanied by benign prostatic hyperplasia, comprising measuring a slowly-inactivating A-type K+ channel opening activity as an index.

20. 发明授权

US5173492A s-Triazolo(3,4-I)purine derivatives 失效
标题翻译：三唑并（3,4-I）嘌呤衍生物
公开(公告)号：US5173492A
公开(公告)日：1992-12-22
申请号：US752180
申请日：1991-08-23
申请人： Fumio Suzuki , Junichi Shimada , Kenji Ohmori , Haruhiko Manabe , Kazuihiro Kubo , Akira Karasawa , Tetsuji Ohno , Shizuo Shiozaki , Akio Ishii , Katsuichi Shuto
发明人： Fumio Suzuki , Junichi Shimada , Kenji Ohmori , Haruhiko Manabe , Kazuihiro Kubo , Akira Karasawa , Tetsuji Ohno , Shizuo Shiozaki , Akio Ishii , Katsuichi Shuto
IPC分类号： C07D471/14
CPC分类号： C07D471/14
摘要： There are disclosed s-triazolo[3,4-i]purine derivatives represented by formula: ##STR1## wherein Y-Z represents ##STR2## R.sub.4 represents hydrogen, alkyl, substituted or unsubstituted aromatic heterocyclic group or substituted or unsubstituted aryl; and X.sup.2 represents oxygen, sulfur or NH; each of R.sup.1 and R.sup.2 independently represents hydrogen, alkyl, cycloalkyl, aralkyl or substituted or unsubstituted aryl; R.sup.3 represents alkyl, cycloalkyl, aralkyl or substituted or unsubstituted aryl; X.sup.1 represents oxygen or sulfur; and represents a single bond or a double bond or pharmaceutically acceptable salts thereof.
摘要翻译：公开了由下式表示的三唑并[3,4-i]嘌呤衍生物：其中Y-Z表示R 4表示氢，烷基，取代或未取代的芳族杂环基或取代或未取代的芳基; X2表示氧，硫或NH; R 1和R 2各自独立地表示氢，烷基，环烷基，芳烷基或取代或未取代的芳基; R3表示烷基，环烷基，芳烷基或取代或未取代的芳基; X1表示氧或硫; 并且表示单键或双键或其药学上可接受的盐。

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