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11. 发明授权

US08087834B2 Optical transmission module, connecting part, and electronic device having optical transmission module 失效
标题翻译：光传输模块，连接部件和具有光传输模块的电子设备
公开(公告)号：US08087834B2
公开(公告)日：2012-01-03
申请号：US12568146
申请日：2009-09-28
申请人： Junichi Tanaka , Akihiko Sano , Toshiaki Okuno , Yoshihisa Ishida , Akira Enami , Hiroshi Sameshima , Naru Yasuda , Hayami Hosokawa
发明人： Junichi Tanaka , Akihiko Sano , Toshiaki Okuno , Yoshihisa Ishida , Akira Enami , Hiroshi Sameshima , Naru Yasuda , Hayami Hosokawa
IPC分类号： G02B6/36 , G02B6/26 , G02B6/24
CPC分类号： G02B6/43 , G02B6/4201 , G02B6/4214
摘要： A connection member (21), which electrically connects a package (14) on which an optical element that converts an electric signal to an optical signal or converts an optical signal to an electric signal and at least one end portion including an incident/releasing port for an optical signal of an optical waveguide (11) that is optically coupled with the optical element to transmit the optical signal are mounted, and a second substrate (2) to each other, is provided with a holding unit having elasticity, which holds the package (14), and a connection unit that is connected to the substrate (2).
摘要翻译：一种连接构件（21），其将将电信号转换为光信号的光学元件或将光信号转换为电信号的封装（14）电连接，并且至少包括入射/释放端口安装与光学元件光学耦合以传输光信号的光波导（11）的光信号，并且第二基板（2）彼此配置有具有弹性的保持单元，其保持封装（14），以及连接到所述基板（2）的连接单元。

12. 发明申请

US20110220406A1 ELECTRODE PORTION STRUCTURE 审中-公开
标题翻译：电极部分结构
公开(公告)号：US20110220406A1
公开(公告)日：2011-09-15
申请号：US12977888
申请日：2010-12-23
申请人： Sayaka Doi , Toshiaki Okuno , Akihiko Sano , Takaaki Miyaji , Yoshiki Hada
发明人： Sayaka Doi , Toshiaki Okuno , Akihiko Sano , Takaaki Miyaji , Yoshiki Hada
IPC分类号： H05K1/11
CPC分类号： H05K3/4038 , H01L21/76898 , H01L24/05 , H01L24/06 , H01L24/13 , H01L24/16 , H01L2224/0401 , H01L2224/05554 , H01L2224/05557 , H01L2224/05558 , H01L2224/05568 , H01L2224/0557 , H01L2224/05572 , H01L2224/05644 , H01L2224/05669 , H01L2224/06181 , H01L2224/131 , H01L2224/16145 , H01L2224/16146 , H01L2224/16238 , H01L2924/0002 , H01L2924/00014 , H01L2924/014 , H01L2224/05552
摘要： In an electrode portion structure in which an electrode is formed in an end portion of a through-wiring, disconnection is prevented in an electrode portion. A through-hole that vertically pierces a substrate is made in the substrate, and a through-electrode is provided in the through-hole. The through-electrode is projected in s curved-surface manner from an upper surface of the substrate. The upper surface of the substrate 12 is coated with an insulating film, and a contact hole is made in the insulating film while aligned with the through-electrode. An opening diameter of the contact hole is lower than a sectional diameter of the through-electrode, and surroundings of an upper surface of the through-electrode are coated with the contact hole. A thickness Ddiel of the insulating film is equal to or lower than a projection length Dp of the through-electrode from the upper surface of the substrate at an opening edge of the contact hole. Additionally, assuming that Dtsv is a projection length (maximum projection length) of an apex of the through-electrode from the upper surface of the substrate, the projection length Dtsv is adjusted so as to become 0≦Dtsv≦Ddiel+Dp (Dp>0).
摘要翻译：在电极形成在贯通布线的端部的电极部结构中，在电极部中防止断线。在衬底中制造垂直穿孔衬底的通孔，并且在通孔中设置通孔。贯通电极从基板的上表面以弯曲表面的方式突出。基板12的上表面涂覆有绝缘膜，并且在绝缘膜中形成与通孔对准的接触孔。接触孔的开口直径低于通孔的截面直径，并且通孔的上表面的周围涂覆有接触孔。绝缘膜的厚度Ddiel等于或低于在接触孔的开口边缘处的基板的上表面的通孔的突出长度Dp。另外，假设Dtsv是从基板的上表面的贯通电极的顶点的突出长度（最大突出长度），将投影长度Dtsv调整为0＆lt; nlE; Dtsv＆nlE; Ddiel + Dp（Dp> 0）。

13. 发明授权

US07341430B2 Vane wheel for torque converter and manufacturing method 失效
标题翻译：叶轮用于变矩器和制造方法
公开(公告)号：US07341430B2
公开(公告)日：2008-03-11
申请号：US11022797
申请日：2004-12-28
申请人： Akihiko Sano , Yoshitaka Miura , Tsutomu Kamitani
发明人： Akihiko Sano , Yoshitaka Miura , Tsutomu Kamitani
IPC分类号： F04D29/38
CPC分类号： F16H41/26
摘要： A vane wheel for torque converter with a plurality of blades formed integrally with a shell in a casting process is disclosed. The blade tilts relative to an axial direction of the vane wheel and has an inner surface located on a positive pressure side thereof and an outer surface located on a negative pressure side thereof. A root thickness in a middle section between an outer periphery side and an inner periphery side of the shell is thicker than a root thickness on the inner periphery side relative to a blade cross section along a circumferential direction from an axis center of the vane wheel.
摘要翻译：公开了一种用于变矩器的叶轮，其具有在铸造过程中与壳体一体形成的多个叶片。叶片相对于叶轮的轴向倾斜，并且具有位于其正压侧的内表面和位于其负压侧的外表面。壳体的外周侧和内周侧之间的中间部分的根部厚度比沿叶轮的轴心的圆周方向相对于叶片截面的内周侧的根部厚度厚。

14. 发明授权

US06756048B1 Long time drug-sustained release preparation 有权
标题翻译：长时间药物缓释制剂
公开(公告)号：US06756048B1
公开(公告)日：2004-06-29
申请号：US09786746
申请日：2001-04-18
申请人： Akihiko Sano , Hiroo Maeda , Masako Kajihara , Shunsuke Tani , Toshihiko Sugie
发明人： Akihiko Sano , Hiroo Maeda , Masako Kajihara , Shunsuke Tani , Toshihiko Sugie
IPC分类号： A61F200
CPC分类号： A61K9/0087 , A61K31/00 , A61K47/30
摘要： The present invention relates to a sustained release preparation of a lipophilic drug, comprising a drug dispersion wherein the lipophilic drug and a water-soluble substance are dispersed, in a solid state at the body temperature of an animal or a human being to which the preparation is to be administered, in a water-impermeable and biocompatible material.
摘要翻译：本发明涉及亲脂性药物的持续释放制剂，其包含药物分散体，其中所述亲脂性药物和水溶性物质以固体状态分散在动物或人的体温，所述制剂将在不透水和生物相容的材料中施用。

15. 发明授权

US5093531A Polyethylene glycol substituted phenyl glyoxals 失效
标题翻译：聚乙二醇取代苯甲酸
公开(公告)号：US5093531A
公开(公告)日：1992-03-03
申请号：US347902
申请日：1989-05-05
申请人： Akihiko Sano , Hiroo Maeda , Yoshiyuki Kai , Keiichi Ono
发明人： Akihiko Sano , Hiroo Maeda , Yoshiyuki Kai , Keiichi Ono
IPC分类号： C12N9/00 , A61K38/00 , C07K1/02 , C07K1/06 , C07K1/107 , C07K1/113 , C07K7/23 , C07K14/00 , C07K14/52 , C07K14/53 , C07K14/535 , C07K14/575 , C07K14/58 , C07K14/60 , C07K14/65 , C08G65/32 , C08G65/323 , C08G65/329 , C08G65/334 , C08G65/48
CPC分类号： C08G65/323 , C07K1/064 , C07K1/1077 , C08G65/329 , C08G65/3346
摘要： A polyethylene glycol derivative of the formula ##STR1## wherein R represents a lower alkyl and n represents an optional positive integer which renders the average molecular weight of the polyethylene glycol moiety about 1,000 to 12,000, a peptide modified by said polyethylene glycol derivative and a method for production thereof.The polyethylene glycol derivative (I) is capable of modifying the guanidino groups in peptides. The peptides modified by the polyethylene glycol derivative (I) are extremely stable, are considerably delayed in biological clearance (i.e. the durability is extended) and exhibit their physiological activities effectively over the long period.

16. 发明授权

US4774319A Synthesis of a derivative of GRF and intermediate peptides 失效
标题翻译： GRF和中间体肽衍生物的合成
公开(公告)号：US4774319A
公开(公告)日：1988-09-27
申请号：US119279
申请日：1987-11-09
申请人： Keiichi Ono , Yoshiyuki Kai , Yoshiaki Takebayashi , Akihiko Sano , Kazushi Suwa
发明人： Keiichi Ono , Yoshiyuki Kai , Yoshiaki Takebayashi , Akihiko Sano , Kazushi Suwa
IPC分类号： A61K38/00 , C07K14/60 , C07K7/06 , C07K7/08 , C07K7/10
CPC分类号： C07K14/60 , A61K38/00 , Y02P20/55 , Y10S930/12
摘要： A process for the manufacture of a polypeptide (I) having the formula: ##STR1## which comprises steps of: (a) coupling, successively and in the order of the sequence of the polypeptide (I), the four protected fragments A, B, C and D or five protected fragments A, B, C, E and F,said fragment A by the formula, Leu-Gin-Asp-Ile-Met-Ser-Arg-NH.sub.2said fragment B by the formula, Gln-Leu-Ser-Ala-Arg-Lys-Leusaid fragment C by the formula, Arg-Lys-Val-Leu-Glysaid fragment D by the formula, Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyrsaid fragment E by the formula, Ile-Phe-Thr-Asn-Ser-Tyrand said fragment F by the formula, Tyr-Ala-Asp-Ala being represented, respectively, and(b) eliminating, at the end of sequence, all the protecting groups to provide the polypeptide (I) which is active on the stimulation of the release of the growth hormone and thus is very useful as medicine for treatment of growth hormone deficiency disease and the like.
摘要翻译：一种制备具有下式的多肽（I）的方法：其包括以下步骤：（a）依次和按照多肽（I ），四个保护的片段A，B，C和D或五个保护的片段A，B，C，E和F，所述片段A通过式Leu-Gin-Asp-Ile-Met-Ser-Arg-NH2表示片段B由式Gln-Leu-Ser-Ala-Arg-Lys-Leu表示，由式Arg-Lys-Val-Leu-Gly表示的片段C表示下式的Tyr-Ala-Asp-Ala- Ile-Phe-Thr-Asn-Ser-Tyr分别表示分子式为Ile-Phe-Thr-Asn-Ser-Tyr的片段E和由式Tyr-Ala-Asp-Ala表示的所述片段F，以及（b）在序列结束时，除去所有保护基以提供在刺激生长激素释放方面具有活性的多肽（I），因此作为治疗生长激素缺乏症的药物非常有用，类似。

17. 发明授权

US09040062B2 Preparation for treatment of spinal cord injury 有权
标题翻译：脊髓损伤的治疗准备
公开(公告)号：US09040062B2
公开(公告)日：2015-05-26
申请号：US13814341
申请日：2011-08-04
申请人： Miho Maeda , Akiyoshi Kishino , Akihiko Sano , Hideyuki Okano , Masaya Nakamura , Liang Zhang
发明人： Miho Maeda , Akiyoshi Kishino , Akihiko Sano , Hideyuki Okano , Masaya Nakamura , Liang Zhang
IPC分类号： A61K9/00 , A61K9/70 , A61K47/34 , A61K31/352 , A61K47/28 , A61K47/02 , A61K47/38 , A61P25/00 , A61P43/00
CPC分类号： A61K9/0024 , A61K9/0085 , A61K9/7007 , A61K31/352 , A61K47/02 , A61K47/28 , A61K47/34 , A61K47/38
摘要： The present invention is a solid sustained-release formulation comprising an agent for inhibiting semaphorin 3A as an active ingredient, which comprises an agent for inhibiting semaphorin 3A and pharmaceutically acceptable hardly water-soluble solid substance, in which the carrier is silicone.
摘要翻译：本发明是一种固体缓释制剂，其包含用于抑制信号素3A作为活性成分的试剂，其包含用于抑制信号素3A和药学上可接受的几乎不溶于水的固体物质的试剂，其中载体是硅氧烷。

18. 发明授权

US08052031B2 Bonding structures for containers and method of bonding same 有权
标题翻译：用于容器的粘合结构及其粘合方法
公开(公告)号：US08052031B2
公开(公告)日：2011-11-08
申请号：US11900747
申请日：2007-09-13
申请人： Akihiko Sano , Yoshitaka Miura
发明人： Akihiko Sano , Yoshitaka Miura
IPC分类号： B23K20/12
CPC分类号： B23K20/126 , B23K20/1225 , B23K33/00 , F16H41/24 , F16H41/28 , F16H2041/243
摘要： A bonding structure for a container member is disclosed. The container member has an opening and a covering member for covering the opening. The container member and covering member are abutted with each other and bonded by a friction stir welding operation. The bonding structure for the container and covering members comprises a bonding portion and a backing member. The bonding portion of the container member and the covering member is formed by inserting a friction stir welding tool into an abutting portion of the container member and the covering member. The backing member is provided for obstructing a plastic flow of materials for the container member and the covering member when the friction stir welding operation is performed. The backing member is disposed adjacent to the bonding portion, at a side of the abutting portion that is opposite to an inserting side of the friction stir welding tool.
摘要翻译：公开了一种用于容器构件的接合结构。容器构件具有用于覆盖开口的开口和覆盖构件。容器构件和覆盖构件彼此抵接并通过摩擦搅拌焊接操作结合。用于容器和覆盖构件的接合结构包括接合部分和背衬构件。容器构件和覆盖构件的接合部分通过将摩擦搅拌焊接工具插入容器构件和覆盖构件的抵接部分而形成。背衬构件被设置用于当执行摩擦搅拌焊接操作时阻挡用于容器构件和覆盖构件的材料的塑性流动。背衬构件邻近结合部设置在与摩擦搅拌焊接工具的插入侧相对的抵接部的一侧。

19. 发明申请

US20110221056A1 ELECTRODE STRUCTURE AND MICRODEVICE PACKAGE PROVIDED THEREWITH 审中-公开
标题翻译：电极结构和MICRODEVICE包提供
公开(公告)号：US20110221056A1
公开(公告)日：2011-09-15
申请号：US12976244
申请日：2010-12-22
申请人： Takaaki Miyaji , Akihiko Sano , Tadashi Inoue , Toshiaki Okuno , Yoshiki Hada , Sayaka Doi , Yoshiki Ashihara
发明人： Takaaki Miyaji , Akihiko Sano , Tadashi Inoue , Toshiaki Okuno , Yoshiki Hada , Sayaka Doi , Yoshiki Ashihara
IPC分类号： H01L23/488
CPC分类号： B81B7/007 , B81B2207/095
摘要： An electrode structure has a Cu electrode that provided in a surface of a substrate, a diffusion preventing film that is made of a material in which a diffusion coefficient of Sn is equal to or lower than 3×10−23 cm2/sec, the whole Cu electrode being covered with the diffusion preventing film, and a solder layer that is provided above the diffusion preventing film, the solder layer being made of Au—Sn solder.
摘要翻译：电极结构具有设置在基板的表面的Cu电极，由扩散系数Sn等于或低于3×10-23cm 2 / sec的材料制成的扩散防止膜，整体 Cu电极被扩散防止膜覆盖，以及设置在扩散防止膜上方的焊料层，焊料层由Au-Sn焊料制成。

20. 发明申请

US20110028535A1 OLIGONUCLEOTIDES-TRANSFERRING PREPARATIONS 审中-公开
标题翻译：寡核苷酸转移制剂
公开(公告)号：US20110028535A1
公开(公告)日：2011-02-03
申请号：US12904054
申请日：2010-10-13
申请人： Shunichiro KUBOTA , Masaaki Terada , Takahiro Ochiya , Hiroshi Itoh , Masayasu Furuse , Akihiko Sano , Shunji Nagahara
发明人： Shunichiro KUBOTA , Masaaki Terada , Takahiro Ochiya , Hiroshi Itoh , Masayasu Furuse , Akihiko Sano , Shunji Nagahara
IPC分类号： A61K48/00
CPC分类号： A61K9/0024 , A61K9/0019 , A61K9/127 , A61K9/19 , A61K9/2063 , A61K9/7007 , A61K31/7105 , A61K31/711 , A61K47/42 , A61K48/00 , A61K48/0008
摘要： Preparations for transferring efficiently oligonucleotides necessary in antisense therapy or the like into animal cells so as to be useful in treatment for various diseases, which comprises a collagen as an essential component are provided.
摘要翻译：提供将反义治疗等中必需的寡核苷酸有效转移到动物细胞中以便可用于治疗包括胶原蛋白作为必需成分的各种疾病的制剂。

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