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    • 11. 发明授权
    • 인돌-3-아세트산을 포함하는 광감작제, 및 이를 포함하는광역학적 치료용 키트
    • 含有吲哚-3-乙酸的光敏剂及含有它们的光动力疗法药盒
    • KR100773475B1
    • 2007-11-05
    • KR1020060063841
    • 2006-07-07
    • 주식회사 웰스킨
    • 김동석김소영박경찬
    • A61K31/405A61K31/404A61P35/00
    • A61K31/405A61K41/0057
    • A novel photosensitizer is provided to show relatively high tumor tissue selectivity and minimum side effects. And a composition and a kit for photodynamic therapy comprising the same are provided. A photosensitizer comprises an indole-3-acetic acid represented by the formula(1). A composition for treating cancer comprises 0.001-30 wt.% of the indole-3-acetic acid having the photodynamic activity and is formulated into liquid, semi-solid, solid or aerosol. A kit for treating cancer of skin, digestive organs, urinary organs, genital organs, respiratory organs, circulatory organs, brain and nervous system comprises the composition and a light source for radiating light having a wavelength of 280-1,000 nm and the strength of 1-100J/cm^2.
    • 提供了一种新颖的光敏剂来显示相对较高的肿瘤组织选择性和最小的副作用。 并提供了包含该组合物和用于光动力疗法的试剂盒。 光敏剂包含由式(1)表示的吲哚-3-乙酸。 用于治疗癌症的组合物包含0.001-30重量%的具有光动力学活性的吲哚-3-乙酸,并且配制成液体,半固体,固体或气溶胶。 用于治疗皮肤,消化器官,泌尿器官,生殖器官,呼吸器官,循环器官,脑和神经系统的癌症的试剂盒包括用于辐射波长为280-1,000nm的光的组合物和光源,强度为1 -100J /平方公分。
    • 17. 发明公开
    • 스핑고실포스포릴콜린 및 그 유도체를 포함하는 미백조성물
    • 含有磷脂酰基胆碱的白色组合物及其衍生物
    • KR1020040073148A
    • 2004-08-19
    • KR1020030009132
    • 2003-02-13
    • 주식회사 웰스킨
    • 박경찬김동석박서형
    • A61K8/68A61Q19/02
    • A61K8/68A61K2800/782A61Q19/02
    • PURPOSE: A whitening composition containing sphingosylphosphorylcholine and derivatives thereof is provided, thereby inhibiting production of melanin from melanin cells, and stimulating ERK(Extracellular signal-regulated kinase) activity to inhibit tyrosinase activity, so that melanin formation can be significantly reduced. CONSTITUTION: The whitening composition contains 0.0001 to 10 wt.% of sphingosylphosphorylcholine(SPC) and derivatives thereof, wherein the whitening composition contains further ultraviolet blocking agent and light scattering agent; and the whitening composition has a formulation selected from cosmetic water, lotion, cream, pack, external ointment.
    • 目的:提供含有鞘糖基磷酰胆碱及其衍生物的美白组合物,从而抑制黑色素细胞产生黑色素,刺激ERK(细胞外信号调节激酶)活性抑制酪氨酸酶活性,从而显着降低黑色素的形成。 构成:增白组合物含有0.0001〜10重量%的鞘糖基磷酰胆碱(SPC)及其衍生物,其中增白组合物含有其它紫外线阻断剂和光散射剂; 并且美白组合物具有选自化妆水,洗剂,霜剂,包装,外用软膏剂的制剂。
    • 19. 发明公开
    • 포스페티딜콜린을 포함하는 섬유화 유도용 조성물 및 상기조성물을 이용한 섬유화 유도방법
    • 用于诱导纤维组织的磷酰胆碱组合物及其诱导纤维组织的方法
    • KR1020040015533A
    • 2004-02-19
    • KR1020020047816
    • 2002-08-13
    • 주식회사 웰스킨
    • 박경찬권선방김동석최혜령정승용
    • A61K31/685
    • PURPOSE: Provided are a phosphatidylcholine composition for inducing fibrous tissue and a method of inducing fibrous tissue using the same, thereby easily inducing fibrosis of dermal tissue, changing an external form of skin tissue, and shrinking the skin. CONSTITUTION: A phosphatidylcholine composition for inducing fibrous tissue comprises 0.01-30 wt.% of phosphatidylcholine or its derivatives selected from the group consisting of O-methyl phosphatidylcholine, O-ethyl phosphatidylcholine, di-myristoyl phosphatidylcholine, di-palmitoyl phosphatidylcholine, di-tetradecanoyl phosphatidylcholine, di-hexadecanoyl phosphatidylcholine, di-oleyl phosphatidylcholine, di-octadecanoyl phosphatidylcholine, di-inoleyl phosphatidylcholine and their substituted compounds, in which phosphatidylcholine is substituted by palmitate, stearate or oleic acid.
    • 目的:提供用于诱导纤维组织的磷脂酰胆碱组合物和使用其的诱导纤维组织的方法,从而容易诱导皮肤组织的纤维化,改变外部形式的皮肤组织和收缩皮肤。 构成:用于诱导纤维组织的磷脂酰胆碱组合物包含0.01-30重量%的磷脂酰胆碱或其衍生物,其选自O-甲基磷脂酰胆碱,O-乙基磷脂酰胆碱,二肉豆蔻酰磷脂酰胆碱,二棕榈酰磷脂酰胆碱,二十四烷酰基 磷脂酰胆碱,二十六烷酰磷脂酰胆碱,二油基磷脂酰胆碱,二十八烷酰磷脂酰胆碱,二烯醇基磷脂酰胆碱及其取代的化合物,其中磷脂酰胆碱被棕榈酸酯,硬脂酸酯或油酸取代。
    • 20. 发明授权
    • 준동기 부호분할 다원접속 시스템의 낮은 상관구역 수열군생성 장치 및 방법
    • 준동기부호분할다원접속시스템의낮은상관구역수열군생성장치및방준
    • KR100656826B1
    • 2006-12-13
    • KR1020050128496
    • 2005-12-23
    • 주식회사 케이티재단법인서울대학교산학협력재단
    • 노종선장지웅김동석유치훈최지영정하봉
    • H04J13/10
    • A device and a method for generating a low correlation zone sequence sets in a sub-synchronous CDMA system are provided to improve performance of the sub-synchronous CDMA system by generating row sequence sets having good correlation characteristics, thereby minimizing interference between users in the sub-synchronous CDMA system and accordingly lowering a signal-to-noise ratio. A device for generating a low correlation zone sequence sets in a sub-synchronous CDMA(Code Division Multiple Access) system comprises the followings: a progression generating unit(100) which generates and outputs a progression(sequences) S(t) having ideal autocorrelation characteristics; a delay unit(200) which delays the sequences, generated in the progression generating unit(100), in order and outputting the sequences; and a matrix generating and row order rearranging unit(300) for rearranging a matrix generated in the delay unit(200) and outputting the row progressions.
    • 提供了一种用于在次同步CDMA系统中生成低相关区域序列组的设备和方法,以通过生成具有良好相关特性的行序列组来提高次同步CDMA系统的性能,从而使子用户之间的干扰最小化 - 同步CDMA系统,并相应地降低了信噪比。 一种用于在次同步CDMA(码分多址)系统中产生低相关区序列集的设备包括以下部分:进展产生单元(100),其产生并输出具有理想自相关性的进展(序列)S(t) 特点; 延迟单元(200),其按顺序延迟在所述进展生成单元(100)中生成的所述序列并输出所述序列; 以及矩阵生成和行顺序重新排列单元(300),用于重新排列在延迟单元(200)中生成的矩阵并输出行进程。