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1. 发明公开

KR1020090001013A 인돌-3-알킬카복실산을 함유하는 여드름 치료제 및 피지분비 억제제, 및 이를 포함하는 광역학적 치료용 키트 无效
标题翻译： ACNE治疗剂和包含吲哚-3-甲酰胆碱的SEBUM SECERNENT INHIBITOR和用于含有它的光动力疗法的胶囊
公开(公告)号：KR1020090001013A
公开(公告)日：2009-01-08
申请号：KR1020070065046
申请日：2007-06-29
申请人： 주식회사 웰스킨
发明人： 김동석 , 김소영 , 권선방
IPC分类号： A61K31/405 , A61P17/10
CPC分类号： A61K41/0057 , A61K31/405 , A61K41/0038
摘要： A photosensitive agent for treating the pimple, a photosensitive agent for inhibiting the secretion of sebum, and a composition or a kit using the agent are provided to improve the pimple treating effect and the anti-sebum effect. A photosensitive agent for treating the pimple comprises an indole-3-alkylcarboxylic acid represented by the formula 1, or its pharmaceutically acceptable salt, wherein n is an integer of 0-3. Preferably the agent shows a photosensitivity to the light of 280-1,000 nm.
摘要翻译：提供用于治疗痘痘的感光剂，用于抑制皮脂分泌的感光剂，以及使用该试剂的组合物或试剂盒，以改善疙瘩治疗效果和抗皮脂效果。用于处理疙瘩的光敏剂包含由式1表示的吲哚-3-烷基羧酸或其药学上可接受的盐，其中n为0-3的整数。优选地，该试剂对280-1,000nm的光显示出光敏性。

2. 发明授权

KR100773475B1 인돌-3-아세트산을 포함하는 광감작제, 및 이를 포함하는광역학적 치료용 키트 有权
标题翻译：含有吲哚-3-乙酸的光敏剂及含有它们的光动力疗法药盒
公开(公告)号：KR100773475B1
公开(公告)日：2007-11-05
申请号：KR1020060063841
申请日：2006-07-07
申请人： 주식회사 웰스킨
发明人： 김동석 , 김소영 , 박경찬
IPC分类号： A61K31/405 , A61K31/404 , A61P35/00
CPC分类号： A61K31/405 , A61K41/0057
摘要： A novel photosensitizer is provided to show relatively high tumor tissue selectivity and minimum side effects. And a composition and a kit for photodynamic therapy comprising the same are provided. A photosensitizer comprises an indole-3-acetic acid represented by the formula(1). A composition for treating cancer comprises 0.001-30 wt.% of the indole-3-acetic acid having the photodynamic activity and is formulated into liquid, semi-solid, solid or aerosol. A kit for treating cancer of skin, digestive organs, urinary organs, genital organs, respiratory organs, circulatory organs, brain and nervous system comprises the composition and a light source for radiating light having a wavelength of 280-1,000 nm and the strength of 1-100J/cm^2.
摘要翻译：提供了一种新颖的光敏剂来显示相对较高的肿瘤组织选择性和最小的副作用。并提供了包含该组合物和用于光动力疗法的试剂盒。光敏剂包含由式（1）表示的吲哚-3-乙酸。用于治疗癌症的组合物包含0.001-30重量％的具有光动力学活性的吲哚-3-乙酸，并且配制成液体，半固体，固体或气溶胶。用于治疗皮肤，消化器官，泌尿器官，生殖器官，呼吸器官，循环器官，脑和神经系统的癌症的试剂盒包括用于辐射波长为280-1,000nm的光的组合物和光源，强度为1 -100J /平方公分。

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