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11. 发明申请

US20050030605A1 Stationary coil oscillator scanning system 有权
公开(公告)号：US20050030605A1
公开(公告)日：2005-02-10
申请号：US10801319
申请日：2004-03-16
申请人： Roger Cannon , Timothy Green , Martin Klement , Daniel Pawley , Wilson Routt
发明人： Roger Cannon , Timothy Green , Martin Klement , Daniel Pawley , Wilson Routt
IPC分类号： G02B26/08 , G02B26/10 , G05B1/00
CPC分类号： G02B26/0833 , G02B26/085 , G02B26/105
摘要： An image scanning apparatus and a torsion oscillator are capable of operating across a dynamic range of possible operating frequencies. The image scanning apparatus uses a light source to produce a light beam, and the oscillator scans the light beam through a scanning pattern. The oscillator includes a plate member having a non-rectangular shape. At least one magnet is disposed on the plate. A surface of the plate member includes a reflective surface for reflecting a light beam. A frame is disposed in a spaced apart relation to a lower surface of the plate member. The frame includes at least one coil configured to induce an electromagnetic force on the at least one magnet to thereby oscillate the reflective surface to a rotational angle of oscillation at an oscillation frequency. The system also includes an imaging surface disposed in the path of the scanning pattern so that the light beam scans across the imaging surface, and a mechanical drive to move the imaging surface. A control system controls electric current provided to the at least one coil to achieve the oscillation.

12. 发明授权

US06305804B1 Non-invasive measurement of blood component using retinal imaging 失效
标题翻译：使用视网膜成像对血液成分进行非侵入性测量
公开(公告)号：US06305804B1
公开(公告)日：2001-10-23
申请号：US09534782
申请日：2000-03-24
申请人： Mark J. Rice , Robert H. Sweat, Jr. , James M. Rioux , William T. Williams , Wilson Routt
发明人： Mark J. Rice , Robert H. Sweat, Jr. , James M. Rioux , William T. Williams , Wilson Routt
IPC分类号： A61B310
CPC分类号： A61B5/14532 , A61B3/1233 , A61B3/145 , A61B5/0013 , A61B5/14546 , A61B5/1455
摘要： Illuminating light of selected wavelengths in the visible or infrared range is projected through the pupil of the eye onto the fundus, and the light reflected back and out through the pupil is detected and analyzed, preferably using the area of the optic disk for analyzing the retinal vessels overlying the optic disk. Specific wavelengths of illuminating light may be chosen for each blood component to be analyzed depending on the spectral characteristics of the substance being analyzed. The reflected image from the retina may be used to measure non-photoreactive blood components such as hemoglobin, and photoreactive components such as bilirubin. For the measurement of photoreactive components, images may be taken before and after, or during, illumination of the eye with light at wavelengths which will affect the photoreactive analyte, enabling measurements of the concentration of the analyte.
摘要翻译：可见光或红外范围内所选波长的照明光通过眼睛的瞳孔投射到眼底，并且通过瞳孔反射回来的光被检测和分析，优选地使用用于分析视网膜的视盘的区域覆盖视盘的血管。可以根据被分析物质的光谱特性，为要分析的每个血液成分选择照射光的特定波长。来自视网膜的反射图像可以用于测量非光反应性血液成分如血红蛋白和光反应性成分如胆红素。对于光反应性成分的测量，可以在影响光反应性分析物的波长处的光照射之前或之后拍摄图像，从而能够测量分析物的浓度。

13. 发明申请

US20050187443A1 Non-invasive measurement of blood analytes using photodynamics 审中-公开
公开(公告)号：US20050187443A1
公开(公告)日：2005-08-25
申请号：US11117818
申请日：2005-04-29
申请人： Wilson Routt , Mark Rice
发明人： Wilson Routt , Mark Rice
IPC分类号： A61B3/12 , A61B5/00
CPC分类号： A61B5/1455 , A61B3/12 , A61B5/14532 , A61B5/14558
摘要： The determination of blood glucose in an individual is carried out by projecting illuminating light into an eye of the individual to illuminate the retina with the light having wavelengths that are absorbed by rhodopsin and with the intensity of the light varying in a prescribed temporal manner. The light reflected from the retina is detected to provide a signal corresponding to the intensity of the detected light, and the detected light signal is analyzed to determine the changes in form from that of the illuminating light. For a biased sinusoidal illumination, these changes can be expressed in terms of harmonic content of the detected light. The changes in form of the detected light are related to the ability of rhodopsin to absorb light and regenerate, which in turn is related to the concentration of blood glucose, allowing a determination of the relative concentration of blood glucose. Other photoreactive analytes can similarly be determined by projecting time varying illuminating light into the eye, detecting the light reflected from the retina, and analyzing the detected light signal to determine changes in form of the signal due to changes in absorptivity of a photoreactive analyte.

14. 发明申请

US20050134143A1 Optical system for torsion oscillator laser scanning unit 有权
标题翻译：用于扭转振荡器激光扫描单元的光学系统
公开(公告)号：US20050134143A1
公开(公告)日：2005-06-23
申请号：US11034168
申请日：2005-01-12
申请人： Roger Cannon , Wilson Routt
发明人： Roger Cannon , Wilson Routt
IPC分类号： G02B26/10 , G02B26/08
CPC分类号： G02B26/105
摘要： An optical apparatus compensates for imaging errors associated with the sinusoidal angular scan rate of a light beam reflected from a bidirectional scanning torsion oscillator. The compensation is achieved by a combination of pre-scan optics positioned between the source of the light beam and the scanning torsion oscillator, and post-scan optics positioned between the scanning torsion oscillator and an imaging surface of an imaging device. Based on the optical characteristics of its components, the post-scan optical system causes deflection of the light beam in the scan direction. To compensate for the sinusoidal scan rate, the deflection caused by the post-scan optical system is greater at the opposing edge positions of the imaging surface than at a central position. In this manner, the scan rate of the light beam at the first and second edge positions is substantially equivalent to the scan rate at the central position. The pre-scan optical system directs the light beam onto the reflective surface of the torsion oscillator in a manner that compensates for divergence of the light beam in the scan direction caused by the post-scan optical system.
摘要翻译：光学装置补偿与从双向扫描扭转振荡器反射的光束的正弦角扫描速率相关联的成像误差。补偿通过位于光束源和扫描扭转振荡器之间的预扫描光学器件和位于扫描扭转振荡器和成像装置的成像表面之间的后扫描光学器件的组合来实现。基于其组件的光学特性，后扫描光学系统导致光束在扫描方向上的偏转。为了补偿正弦扫描速率，由扫描后光学系统引起的偏转在成像表面的相对边缘位置处比在中心位置处更大。以这种方式，第一和第二边缘位置处的光束的扫描速率基本上等于在中心位置处的扫描速率。预扫描光学系统以补偿由扫描后光学系统引起的扫描方向上的光束发散的方式将光束引导到扭转振荡器的反射表面上。

15. 发明授权

US06895264B2 Non-invasive psychophysical measurement of glucose using photodynamics 失效
标题翻译：使用光动力学对葡萄糖进行非侵入性心理物理测量
公开(公告)号：US06895264B2
公开(公告)日：2005-05-17
申请号：US10642111
申请日：2003-08-15
申请人： Mark J. Rice , Joe W. Woods , Wilson Routt , Junli Ou
发明人： Mark J. Rice , Joe W. Woods , Wilson Routt , Junli Ou
IPC分类号： A61B3/06 , A61B3/103 , A61B5/00
CPC分类号： A61B5/1455 , A61B3/066 , A61B3/103 , A61B5/14532
摘要： Blood glucose concentrations are measured by non-invasive methods and apparatus using visual pigment bleaching in conjunction with psychophysical methodologies. Bleaching light of selected wavelengths is projected through the pupil of the eye of an observer onto the fundus to bleach visual pigments in the eye. The observer's psychophysical response to a visual stimulus is then measured to obtain information regarding the rate of regeneration of the visual pigments. From the rate of pigment regeneration, blood glucose concentrations are measured accurately. The psychophysical methodologies that may be used with the invention include visual acuity tests and color-matching tests.
摘要翻译：通过非侵入性方法和装置使用视觉色素漂白与心理物理学方法结合来测量血糖浓度。所选波长的漂白光通过观察者的眼睛的瞳孔投射到眼底上以漂白眼睛中的视觉颜料。然后测量观察者对视觉刺激物的心理物理反应，以获得关于视觉颜料再生速率的信息。从色素再生的速度，准确测量血糖浓度。可用于本发明的心理物理学方法包括视力测试和颜色匹配测试。

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