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    • 11. 发明申请
    • DISTRIBUTED PHYSICS BASED TRAINING SYSTEM AND METHODS
    • 基于分布式物理学的培训系统和方法
    • WO2007062260A2
    • 2007-05-31
    • PCT/US2006/045569
    • 2006-11-28
    • L-3 COMMUNICATIONS CORPORATIONFALASH, MarkPOLLAK, EytanCHEN, YushanWILLIAMS, Jon
    • FALASH, MarkPOLLAK, EytanCHEN, YushanWILLIAMS, Jon
    • G06T15/00
    • G09B9/00H04L67/38
    • A distributed simulation system is composed of simulator stations linked over a network that each renders real-time video imagery for its user from scene data stored in its data storage. The simulation stations are each connected with a physics farm that manages the virtual objects in the shared virtual environment based on their physical attribute data using physics engines, including an engine at each simulation station. The physics engines of the physics farm are assigned virtual objects so as to reduce the effects of latency, to ensure fair fight requirements of the system, and, where the simulation is of a vehicle, to accurately model the ownship of the user at the station. A synchronizer system is also provided that allows for action of simulated entities relying on localized closed loop controls to cause the entities to meet specific goal points at specified system time points.
    • 分布式仿真系统由通过网络链接的模拟站组成,每个模拟站通过存储在其数据存储器中的场景数据为用户提供实时视频图像。 模拟站各自与物理场连接,该物理场基于使用物理引擎(包括每个模拟站处的引擎)的物理属性数据来管理共享虚拟环境中的虚拟对象。 物理场的物理引擎被分配虚拟对象,以减少延迟的影响,以确保系统的公平对抗要求,以及在模拟车辆的情况下,准确地对车站用户进行建模 。 还提供了同步器系统,其允许依赖于本地化闭环控制的模拟实体的动作使得实体在指定的系统时间点满足特定的目标点。
    • 12. 发明申请
    • TREATMENT OF CARCINOMAS USING SQUALAMINE IN COMBINATION WITH OTHER ANTI-CANCER AGENTS OR MODALITIES
    • 用其他抗癌药或联合方案治疗癌症
    • WO0015176A3
    • 2000-07-20
    • PCT/US9920645
    • 1999-09-10
    • MAGAININ PHARMAZASLOFF MICHAELWILLIAMS JONSOKOLOFF MITCHELL H
    • ZASLOFF MICHAELWILLIAMS JONSOKOLOFF MITCHELL H
    • A61K45/00A61K31/00A61K31/136A61K31/166A61K31/167A61K31/17A61K31/198A61K31/351A61K31/407A61K31/41A61K31/437A61K31/506A61K31/513A61K31/519A61K31/565A61K31/575A61K31/7004A61K33/24A61K33/42A61P5/02A61P5/28A61P35/00A61K31/595
    • A61K31/00A61K31/575A61K2300/00
    • A method for treating a tumor includes a first treatment procedure using a conventional cancer treatment technique, and a second treatment procedure which includes administering an effective amount of squalamine. Synergistically effective amounts are preferred. The first treatment procedure may be a treatment with one or more conventional cytotoxic chemical compounds. As examples, the cytotoxic chemical compound may be a nitrosourea (such as BCNU), cyclophosphamide, doxorubicin, 5-fluorouracil, paclitaxel and its derivatives, cisplatin or other platinum containing cancer treating agents. Alternatively, the first treatment may be a treatment with one or more conventional anti-hormonal agents. As examples, the anti-hormonal agents may be a LHRH (luteinizing hormone releasing hormone) agonist or an anti-androgen such as flutamide, biclutamide, nilutamide, and luprolide. These conventional cancer treatments compounds and the squalamine may be administered by any suitable route. The first treatment procedure may take place prior to the second treatment procedure, after the second treatment procedure, or the two treatment procedures may take place simultaneously. As an alternative, the first treatment procedure may be a conventional radiation treatment regimen. As a further alternative the first treatment procedure may be a combination of treatment with one or more conventional cytotoxic chemical compounds and a conventional radiation treatment regimen.
    • 治疗肿瘤的方法包括使用常规癌症治疗技术的第一治疗程序和包括施用有效量的角鲨胺的第二治疗程序。 协同有效量是优选的。 第一治疗程序可以是用一种或多种常规细胞毒化学化合物治疗。 作为实例,细胞毒化学化合物可以是亚硝基脲(例如BCNU),环磷酰胺,阿霉素,5-氟尿嘧啶,紫杉醇及其衍生物,顺铂或其他含有铂的癌症治疗剂。 或者,第一次治疗可以是用一种或多种常规抗激素药物治疗。 作为实例,抗激素药可以是LHRH(促黄体激素释放激素)激动剂或抗雄激素药,例如氟他胺,双氯苯酰胺,尼鲁米特和亮丙瑞林。 这些常规的癌症治疗化合物和角鲨胺可以通过任何合适的途径施用。 第一治疗程序可以在第二治疗程序之前,第二治疗程序之后或两个治疗程序可以同时进行。 作为替代,第一治疗程序可以是常规的放射治疗方案。 作为另一种选择,第一治疗程序可以是用一种或多种常规细胞毒化学化合物治疗和常规放射治疗方案的组合。
    • 15. 发明申请
    • TAP DETECTION
    • TAP检测
    • WO2010047932A1
    • 2010-04-29
    • PCT/US2009/059220
    • 2009-10-01
    • ANALOG DEVICES, INC.LEE, James, M.WILLIAMS, Jon, Austen
    • LEE, James, M.WILLIAMS, Jon, Austen
    • G06F3/01G06F3/033
    • G06F3/017G06F3/033G06F3/0346G06F2200/1636
    • Methodology and circuitry for determining if a device, such as a cellular phone or personal digital assistant has been tapped is disclosed. The device includes an accelerometer and in response to an acceleration, the accelerometer outputs an acceleration signal. The accelerometer may continuously output an acceleration signal even if no acceleration occurs. A tap detection device receives the temporally sampled acceleration signal and takes the first derivative of the temporally sampled acceleration signal producing one or more derivative values. The tap detection system compares each derivative value to a threshold value and if the derivative value exceeds the threshold a tap is detected. By taking the derivative of the acceleration signal, the noise floor for the acceleration signal is reduced leading to more accurate results with less false positives and less positive negatives.
    • 公开了用于确定诸如蜂窝电话或个人数字助理之类的设备是否被轻敲的方法和电路。 该装置包括加速度计,并且响应于加速度,加速度计输出加速度信号。 即使没有加速度发生,加速度计也可以连续地输出加速度信号。 抽头检测装置接收时间采样的加速度信号,并取得时间采样的加速度信号的一阶导数,产生一个或多个导数值。 抽头检测系统将每个导数值与阈值进行比较,并且如果导数值超过阈值,则检测到抽头。 通过采用加速度信号的导数,减小加速度信号的本底噪声,从而导致更准确的结果,更少的误报和较小的正负。