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11. 发明申请

WO2022094740A1 CONTROLLED TRAINING AND USE OF TEXT-TO-SPEECH MODELS AND PERSONALIZED MODEL GENERATED VOICES 审中-公开
公开(公告)号：WO2022094740A1
公开(公告)日：2022-05-12
申请号：PCT/CN2020/126047
申请日：2020-11-03
申请人： MICROSOFT TECHNOLOGY LICENSING, LLC , ZHAO, Sheng , JIANG, Li , HUANG, Xuedong , QIN, Lijuan , HE, Lei , DING, Binggong , YAN, Bo , MA, Chunling , OBEROI, Raunak
发明人： ZHAO, Sheng , JIANG, Li , HUANG, Xuedong , QIN, Lijuan , HE, Lei , DING, Binggong , YAN, Bo , MA, Chunling , OBEROI, Raunak
IPC分类号： G10L13/02
摘要： Systems are configured for generating text-to-speech data in a personalized voice by training a neural text-to-speech machine learning model on natural speech data collected from a particular user, validating the identity of the user from which data is collected, and authorizing requests from users to use the personalized voice in generating new speech data. The systems are further configured to train a machine learning model as a neural text-to-speech model with generated personalized speech data.

12. 发明申请

WO2010023517A3 DETECTING GAS COMPOUNDS FOR DOWNHOLE FLUID ANALYSIS 审中-公开
标题翻译：检测气体混合物用于井下流体分析
公开(公告)号：WO2010023517A3
公开(公告)日：2010-04-29
申请号：PCT/IB2009006458
申请日：2009-08-06
申请人： SCHLUMBERGER TECHNOLOGY BV , SCHLUMBERGER SERVICES PETROL , SCHLUMBERGER CA LTD , SCHLUMBERGER HOLDINGS , PRAD RES & DEV LTD , LAWRENCE JIMMY , JONES TIMOTHY G J , INDO KENTARO , YAMATE TSUTOMU , MATSUMOTO NORIYUKI , TORIBIO MICHAEL , YOSHIUCHI HIDETOSHI , MEREDITH ANDREW , LAWRENCE NATHAN S , JIANG LI , FUJISAWA GO , MULLINS OLIVER C
发明人： LAWRENCE JIMMY , JONES TIMOTHY G J , INDO KENTARO , YAMATE TSUTOMU , MATSUMOTO NORIYUKI , TORIBIO MICHAEL , YOSHIUCHI HIDETOSHI , MEREDITH ANDREW , LAWRENCE NATHAN S , JIANG LI , FUJISAWA GO , MULLINS OLIVER C
IPC分类号： E21B49/00 , E21B49/08
CPC分类号： E21B49/005 , E21B49/08
摘要： A gas separation and detection tool for performing in situ analysis of borehole fluid is described. A separation system such as a membrane is employed to separate one or more target gasses from the borehole fluid. The separated gas may be detected by reaction with another material or spectroscopy. When spectroscopy is employed, a test chamber defined by a housing is used to hold the gas undergoing test. Various techniques may be employed to protect the gas separation system from damage due to pressure differential. For example, a separation membrane may be integrated with layers that provide strength and rigidity. The integrated membrane separation may include one or more of a water impermeable layer, gas selective layer, inorganic base layer and metal support layer. The gas selective layer itself can also function as a water impermeable layer. The metal support layer enhances resistance to differential pressure. Alternatively, the chamber may be filled with a liquid or solid material.
摘要翻译：描述了一种用于进行井眼流体原位分析的气体分离和检测工具。使用诸如膜的分离系统将一个或多个目标气体与井眼流体分离。分离的气体可以通过与另一种材料或光谱学的反应来检测。当使用光谱法时，由壳体限定的测试室用于保持气体经受测试。可以采用各种技术来保护气体分离系统免受压力差造成的损害。例如，分离膜可以与提供强度和刚度的层一体化。一体化膜分离可以包括不透水层，气体选择层，无机基底层和金属支撑层中的一种或多种。气体选择层本身也可以用作不透水层。金属支撑层增强了对压差的抵抗力。或者，腔室可以填充有液体或固体材料。

13. 发明申请

WO2006059097A1 OPTICAL PH SENSOR 审中-公开
标题翻译：光学传感器
公开(公告)号：WO2006059097A1
公开(公告)日：2006-06-08
申请号：PCT/GB2005/004589
申请日：2005-12-01
申请人： SCHLUMBERGER HOLDINGS LIMITED , SCHLUMBERGER CANADA LIMITED , SCHLUMBERGER TECHNOLOGY B.V. , SERVICES PETROLIERS SCHLUMBERGER , JIANG, Li , JONES, Timothy, Gareth, John
发明人： JIANG, Li , JONES, Timothy, Gareth, John
IPC分类号： G01N21/77
CPC分类号： G01N21/80 , G01N31/221
摘要： An optical sensor for pH is described using a cross-linked network of bisilanes to immobilize a pH sensitive chromophore to a surface potentially exposed to a high pressure, high temperature environment such as wellbore effluents at a downhole location.
摘要翻译：使用双链烷烃的交联网络描述用于pH的光学传感器，以将pH敏感的发色团固定在潜在暴露于高压，高温环境（例如在井下位置的井眼流出物）的表面。

14. 发明申请

WO2005017514A1 SYSTEM AND METHOD FOR SENSING USING DIAMOND BASED MICROELECTRODES 审中-公开
标题翻译：使用基于金刚石的微电极进行感测的系统和方法
公开(公告)号：WO2005017514A1
公开(公告)日：2005-02-24
申请号：PCT/GB2004/002456
申请日：2004-06-10
申请人： SCHLUMBERGER TECHNOLOGY B.V. , PETROLEUM RESEARCH AND DEVELOPMENT N.V. , SCHLUMBERGER CANADA LIMITED , SCHLUMBERGER HOLDINGS LIMITED , SCHLUMBERGER OILFIELD ASSISTANCE LIMITED , SCHLUMBERGER OVERSEAS S.A. , SCHLUMBERGER SEACO INC. , SCHLUMBERGER SERVICES LIMITED , SCHLUMBERGER SURENCO S.A. , SERVICES PETROLIERS SCHLUMBERGER , JIANG, Li , JONES, Timothy, Gareth, John , HALL, Clive, Edward
发明人： JIANG, Li , JONES, Timothy, Gareth, John , HALL, Clive, Edward
IPC分类号： G01N27/403
CPC分类号： G01N27/403 , E21B49/082
摘要： A method and system is disclosed for monitoring one or more characteristics associated with a fluid. An insulating layer comprising non-conducting diamond (121) is positioned within a housing and has a surface exposed directly or indirectly to the fluid. A plurality of microelectrodes (100) made of electrically conducting diamond each have a surface exposed directly or indirectly to the fluid. An electrical circuit in electrical communication with each of the microelectrodes is adapted to convert electrical signals from the microelectrodes into at least one signal associated with a characteristic being monitored. The sensing system is well suited to hydrocarbon wellbore related applications, but can also be used in other applications.
摘要翻译：公开了用于监测与流体相关联的一个或多个特性的方法和系统。包括非导电金刚石（121）的绝缘层定位在壳体内并且具有直接或间接暴露于流体的表面。由导电金刚石制成的多个微电极（100）各自具有直接或间接暴露于流体的表面。与每个微电极电连通的电路适于将来自微电极的电信号转换为与被监测的特性相关联的至少一个信号。传感系统非常适用于烃井相关应用，但也可用于其他应用。

15. 发明申请

WO2004063743A1 METHODS AND APPARATUS FOR THE MEASUREMENT OF HYDROGEN SULPHIDE AND THIOLS IN FLUIDS 审中-公开
标题翻译：用于测量流体中硫化氢和硫酸的方法和装置
公开(公告)号：WO2004063743A1
公开(公告)日：2004-07-29
申请号：PCT/GB2003/002345
申请日：2003-05-28
申请人： SCHLUMBERGER TECHNOLOGY B.V. , PETROLEUM RESEARCH AND DEVELOPMENT N.V. , SCHLUMBERGER CANADA LIMITED , SCHLUMBERGER HOLDINGS LIMITED , SCHLUMBERGER OILFIELD ASSISTANCE LIMITED , SCHLUMBERGER OVERSEAS S.A. , SCHLUMBERGER SERVICES LIMITED , SCHLUMBERGER SURENCO S.A. , SERVICES PETROLIERS SCHLUMBERGER , JIANG, Li , JONES, Timothy, Gareth, John , BROWN, Jonathan, Webster , GILBERT, Andrew
发明人： JIANG, Li , JONES, Timothy, Gareth, John , BROWN, Jonathan, Webster , GILBERT, Andrew
IPC分类号： G01N33/00
CPC分类号： G01N27/4045 , E21B47/00 , G01N33/287 , Y10T436/184
摘要： An electrochemical sensor for measuring the amount of hydrogen sulphide or thiols in a fluid in a wellbore comprises a temperature- and pressure-resistant housing containing a flow path for the fluids. The fluids flow over one side of a gas permeable membrane made of zeolite or a suitable ceramic material, the other side of the membrane being exposed to a chamber containing a reaction solution which together with the hydrogen sulphide or thiols create a redox reaction resulting in an electrical current dependent upon the amount of hydrogen sulphide or thiols in the fluid.
摘要翻译：用于测量井筒中流体中的硫化氢或硫醇的量的电化学传感器包括耐温和耐压壳体，其包含用于流体的流动路径。流体在由沸石或合适的陶瓷材料制成的透气膜的一侧上流动，膜的另一侧暴露于含有反应溶液的室中，该反应溶液与硫化氢或硫醇一起产生氧化还原反应，导致电流取决于流体中的硫化氢或硫醇的量。

16. 发明申请

WO03035834A3 COMPOSITIONS AND METHODS FOR MAKING MUTATIONS IN CELL LINES AND ANIMALS 审中-公开
标题翻译：用于在细胞系和动物中进行突变的组合物和方法
公开(公告)号：WO03035834A3
公开(公告)日：2003-08-07
申请号：PCT/US0233714
申请日：2002-10-22
申请人： ATHERSYS INC , HARRINGTON JOHN JOSEPH , JACKSON PAUL DAVID , JIANG LI
发明人： HARRINGTON JOHN JOSEPH , JACKSON PAUL DAVID , JIANG LI
IPC分类号： A01H5/00 , A01K67/027 , C12N1/19 , C12N5/10 , C12N15/00 , C12N15/01 , C12N15/09 , C12Q1/04 , C12Q1/68 , A01K67/00 , A01K67/033
CPC分类号： C12N15/102 , C12N15/01 , C12Q1/6897
摘要： The present invention is directed generally to reduction or inactivation of gene function or gene expression in cells in vitro and in multicellular organisms. The invention encompasses methods for mutating cells using a combination of mutagens, particularly wherein at least one mutagen is an insertional mutagen, to achieve homozygous gene mutation or mutation of multiple genes required cumulatively to achieve a phenotype to create knock-outs, knock-downs, and other modifications in the same cell. The invention is also directed to cells (and libraries thereof) and organisms created by the methods of the invention, including those in which at least one of the genes created by insertional mutagenesis is tagged by means of the insertion sequences thereby allowing identification of the mutated gene(s). The invention is also directed to libraries of mutated cells and their uses. The invention is also directed to methods of identifying mutations with methods of the invention, in cells (and libraries thereof) and organisms, bymeans of the insertional tag
摘要翻译：本发明一般涉及体外和多细胞生物体中细胞中基因功能或基因表达的还原或失活。本发明包括使用诱变剂的组合突变细胞的方法，特别是其中至少一种诱变剂是插入型诱变剂，以实现纯合基因突变或累积需要多个基因的突变以实现表型以产生敲除，敲低，和在同一个单元格中的其他修改。本发明还涉及通过本发明的方法产生的细胞（及其文库）和生物体，包括其中通过插入突变产生的至少一个基因通过插入序列进行标记，从而允许识别突变的基因（一个或多个）。本发明还涉及突变细胞的文库及其用途。本发明还涉及通过本发明的方法在细胞（和其文库）和生物体中通过插入标签的方法鉴定突变的方法

17. 发明申请

WO2003040324A3 METHODS FOR MUTATING GENES IN CELLS AND ANIMALS USING INSERTIONAL MUTAGENESIS 审中-公开
公开(公告)号：WO2003040324A3
公开(公告)日：2003-05-15
申请号：PCT/US2002/035405
申请日：2002-11-04
申请人： ATHERSYS, INC. , HARRINGTON, John, Joseph , JACKSON, Paul, David , JIANG, Li
发明人： HARRINGTON, John, Joseph , JACKSON, Paul, David , JIANG, Li
IPC分类号： C12N5/00
摘要： The present invention is in the fields of molecular biology, cell biology, and genetics. The invention is directed generally to mutating genes in cells in vitro and in multi-cellular organisms. The invention encompasses methods for mutating genes in cells using polynucleotides that act as insertional mutagens. Such methods are used to achieve mutation of a single gene to achieve a desired phenotype as well as mutation of multiple genes, required cumulatively to achieve a desired phenotype, in a cell or in a multi-cellular organism. The invention is also directed to methods of identifying one or more mutated genes, made by the methods of the invention, in cells and in multi-cellular organisms, by means of a tagging property provided by the insertional mutagen(s). The insertional mutagen thus allows identification of one or more genes that are mutated by insertion of an insertional mutagen. The invention is also directed to methods for correlating a phenotype with a gene by screening or selecting cells that have been mutated by an insertional mutagen incorporated into one or more genes in a cell and identifying the gene or genes causing the phenotype by means of a tagging property in one or more of the insertional mutagens. The invention is also directed to cells and multi-cellular organisms created by the methods of the invention and uses of the cells and multicellular organisms. The invention is also directed to libraries of cells created by the methods of the invention and uses of the libraries.

18. 发明申请

WO2003035834A2 COMPOSITIONS AND METHODS FOR MAKING MUTATIONS IN CELL LINES AND ANIMALS 审中-公开
标题翻译：用于在细胞系和动物中制备突变的组合物和方法
公开(公告)号：WO2003035834A2
公开(公告)日：2003-05-01
申请号：PCT/US2002/033714
申请日：2002-10-22
申请人： ATHERSYS, INC. , HARRINGTON, John, Joseph , JACKSON, Paul, David , JIANG, Li
发明人： HARRINGTON, John, Joseph , JACKSON, Paul, David , JIANG, Li
IPC分类号： C12N
CPC分类号： C12N15/102 , C12N15/01 , C12Q1/6897
摘要： The present invention is directed generally to reduction or inactivation of gene function or gene expression in cells in vitro and in multicellular organisms. The invention encompasses methods for mutating cells using a combination of mutagens, particularly wherein at least one mutagen is an insertional mutagen, to achieve homozygous gene mutation or mutation of multiple genes required cumulatively to achieve a phenotype to create knock-outs, knock-downs, and other modifications in the same cell. The invention is also directed to cells (and libraries thereof) and organisms created by the methods of the invention, including those in which at least one of the genes created by insertional mutagenesis is tagged by means of the insertion sequences thereby allowing identification of the mutated gene(s). The invention is also directed to libraries of mutated cells and their uses. The invention is also directed to methods of identifying mutations with methods of the invention, in cells (and libraries thereof) and organisms, bymeans of the insertional tag
摘要翻译：本发明总体上涉及体外和多细胞生物体中细胞中基因功能或基因表达的减少或失活。本发明包括使用诱变剂的组合来突变细胞的方法，特别是其中至少一种诱变剂是插入诱变剂，以实现累积需要的多个基因的纯合基因突变或突变以实现表型以产生敲除，敲除，和在同一个单元格中的其他修改。本发明还涉及通过本发明的方法产生的细胞（及其文库）和生物体，包括通过插入序列对至少一个通过插入诱变产生的基因进行标记的细胞，从而允许鉴定突变的基因（一个或多个）。本发明还涉及突变细胞的文库及其用途。本发明还涉及通过插入标记的方法在细胞（及其文库）和生物体中用本发明的方法鉴定突变的方法，

19. 发明申请

WO2013033086A3 METHOD AND COMPOSITION TO REDUCE GEL VISCOSITY IN THE INTERMEDIATE TEMPERATURE RANGE 审中-公开
公开(公告)号：WO2013033086A3
公开(公告)日：2013-03-07
申请号：PCT/US2012/052649
申请日：2012-08-28
申请人： SCHLUMBERGER CANADA LIMITED , SERVICES PETROLIERS SCHLUMBERGER , SCHLUMBERGER HOLDINGS LIMITED , SCHLUMBERGER TECHNOLOGY B.V. , PRAD RESEARCH AND DEVELOPMENT LIMITED , JIANG, Li , ALI, Syed A. , PARRIS, Michael D. , HUTCHINS, Richard D. , OGUNLAJA, Gbenga
发明人： JIANG, Li , ALI, Syed A. , PARRIS, Michael D. , HUTCHINS, Richard D. , OGUNLAJA, Gbenga
IPC分类号： C09K8/58 , C09K8/584
摘要： Methods for reducing a viscosity of a viscosified fluid include reacting, such as by depolymerizing and/or decomposing, a polymeric material of the viscosified fluid with a breaking agent including one or more organic peroxide breakers having a structural feature selected from a cyclic peroxide segment and/or multiple linear peroxide moieties per molecule. The methods of treating the subterranean are provided that include reacting, such as by depolymerizing and/or decomposing, a polymeric material of a viscosified treatment fluid with one or more organic peroxide breakers having a structural feature selected from cyclic peroxide segment and/or multiple linear peroxide moieties per molecule to facilitate breaking of the viscosified treatment fluid after the fracturing or treatment is finished.

20. 发明申请

WO2010036417A3 FUEL COMPOSITION RECOGNITION AND ADAPTATION SYSTEM 审中-公开
标题翻译：燃料组合物识别和适应系统
公开(公告)号：WO2010036417A3
公开(公告)日：2010-05-20
申请号：PCT/US2009046222
申请日：2009-06-04
申请人： ROBERT BOSCH LLC , JIANG LI , OLIVERIO NESTOR H , STEFANOPOULOU ANNA G , YILMAZ HAKAN
发明人： JIANG LI , OLIVERIO NESTOR H , STEFANOPOULOU ANNA G , YILMAZ HAKAN
IPC分类号： F02D35/02 , F02D19/00 , F02D41/00 , F02D41/24
CPC分类号： F02D41/0025 , F02D19/0623 , F02D19/0642 , F02D19/0689 , F02D19/084 , F02D19/088 , F02D35/023 , F02D41/06 , F02D41/22 , F02D41/2441 , F02D41/2451 , F02D41/3029 , F02D41/402 , F02D2200/0612 , Y02T10/36
摘要： A method of operating an internal combustion engine. The method including monitoring a pressure in a combustion chamber of the engine during a compression stroke, determining whether a fuel composition has changed from a first composition to a second composition based at least in part on the monitored pressure, and triggering a fuel composition adaptation in response to a determination that the fuel composition has changed.
摘要翻译：一种操作内燃机的方法。该方法包括在压缩冲程期间监测发动机的燃烧室中的压力，至少部分地基于所监测的压力来确定燃料组成是否已经从第一组成改变为第二组合物，并且触发燃料成分适应响应确定燃料组成已经改变。

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