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    • 12. 发明申请
    • Biosensor comprising interdigitated electrode sensor units
    • 生物传感器包括交错电极传感器单元
    • US20090084686A1
    • 2009-04-02
    • US11991083
    • 2006-08-25
    • Wan-Soo YunHyung-Ju ParkYeung-Shik Chi
    • Wan-Soo YunHyung-Ju ParkYeung-Shik Chi
    • G01N27/327
    • G01N33/5438C12Q2565/607
    • The present invention is related to a biosensor for detecting presence and concentration of various bio-materials such as genes and proteins by the electrical method, an interdigitated electrode sensor unit for forming the biosensor and a method for measuring concentration of a bio-material using the biosensor. The biosensor according to the present invention comprises a plurality of (a) independently-operating interdigitated electrode sensor units integrated on a substrate, wherein each interdigitated electrode sensor unit comprise: first electrode and second electrode formed interdigitatedly and spaced from each other on the substrate; and a sensor-immobilized biomolecule receptor immobilized on the substrate exposed between the first electrode and the second electrode so that the first electrode is electrically connected to the second electrode upon binding to a biomolecule and specifically binding to the biomolecule, wherein the biomolecule is analyzed by the number of the (b) interdigitated electrode sensor units electrically connected by the biomolecule captured by the sensor-immobilized biomolecule receptor.
    • 本发明涉及一种用于通过电气方法检测各种生物材料如基因和蛋白质的存在和浓度的生物传感器,用于形成生物传感器的叉指电极传感器单元和使用该方法测量生物材料的浓度的方法 生物传感器 根据本发明的生物传感器包括集成在基板上的多个(a)独立操作的交叉指状电极传感器单元,其中每个交叉指状电极传感器单元包括:在基板上彼此交叉形成并间隔开的第一电极和第二电极; 以及传感器固定化的生物分子受体,固定在暴露在第一电极和第二电极之间的衬底上,使得第一电极在与生物分子结合并且特异性结合生物分子时与第二电极电连接,其中生物分子由 通过由传感器固定的生物分子受体捕获的生物分子电连接的(b)叉指电极传感器单元的数量。