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    • 123. 发明授权
    • Vacuum device and method for treating tissue adjacent a body cavity
    • 真空装置和用于处理体腔附近的组织的方法
    • US06923754B2
    • 2005-08-02
    • US10290002
    • 2002-11-06
    • Paul Lubock
    • Paul Lubock
    • A61F2/958A61N5/10A61N5/00
    • A61N5/1015A61B2017/22048A61B2017/22051
    • Devices and methods are provided for applying vacuum near to devices for delivering treatments to tissue adjacent a body cavity, effective to draw adjacent tissue near to such devices and to enhance treatment of the tissue. Body cavities include natural body cavities and cavities remaining after removal of tissue such as cancerous tissue. A device may include an inner balloon assembly with an inflation conduit. A sheath assembly having a fluid-permeable sheath wall may enclose the inner balloon assembly. Vacuum applied to the space between the sheath and the inner balloon is useful to draw tissue into contact with the device, improving treatment effectiveness. Methods for treating tissue with such devices and systems are also provided. Treatments may include providing radioactive material for radiation treatment, providing chemotherapeutic material for chemotherapy, providing thermal treatment, and combinations thereof. Systems may include devices of the invention and a vacuum source.
    • 提供了设备和方法,用于在靠近体腔的组织递送治疗装置的地方施加真空,有效地吸引靠近这种装置的邻近组织并增强对组织的治疗。 体腔包括自然体腔和去除组织如癌组织后残留的空腔。 装置可以包括具有充气导管的内气囊组件。 具有流体可渗透护套壁的护套组件可以封闭内部气囊组件。 施加到护套和内囊之间的空间的真空用于使组织与装置接触,提高治疗效果。 还提供了用这种装置和系统处理组织的方法。 治疗可以包括提供用于放射治疗的放射性物质,提供用于化疗的化学治疗材料,提供热治疗及其组合。 系统可以包括本发明的装置和真空源。
    • 125. 发明申请
    • Biopsy device with selectable tissue receiving aperture orientation and site illumination
    • 活组织检查装置,可选择组织接收孔径取向和局部照明
    • US20050065453A1
    • 2005-03-24
    • US10911106
    • 2004-08-03
    • Martin ShabazRichard QuickFrank LouwPaul LubockJason Safabash
    • Martin ShabazRichard QuickFrank LouwPaul LubockJason Safabash
    • A61B10/00A61B10/02A61B17/00A61B17/32A61B17/34
    • A61B10/0275A61B10/0266A61B10/0283A61B17/32002A61B17/3417A61B90/30A61B2010/0208A61B2010/0225A61B2017/00473A61B2017/00486A61B2017/3405A61B2090/3908A61B2090/3987
    • The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component with an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component to which the probe component is releasably secured. The driver has a drive member for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational to effectively separate a tissue specimen from tissue extending through the aperture in the tubular section.
    • 本发明涉及一种用于从患者内的目标部位分离和收集组织标本的系统和装置。 该装置包括具有细长管状部分的探针部件,穿透远侧末端和在远端顶端的管状部分的远端中的组织接收孔,以及组织切割构件,其可滑动地设置在探针构件内以切割 组织样本通过向组织切割构件的内腔施加真空而通过孔被拉入装置的内部。 该装置还具有驱动器部件,探针组件可释放地固定到该部件上。 驱动器具有用于调节管状部分的方向并因此调节其中的孔的驱动构件和一个或多个驱动构件,用于移动管状区段内的组织切割构件以将组织样本从延伸到管状部分内部的组织切断 通过光圈。 赋予组织切割器的运动至少是纵向的,并且优选也是振动和/或旋转以有效地将组织样本与延伸穿过管状部分中的孔的组织分离。
    • 127. 发明授权
    • Breast biopsy system and methods
    • 乳腺活检系统及方法
    • US06699206B2
    • 2004-03-02
    • US09976916
    • 2001-10-11
    • Fred H. BurbankMichael L. JonesPaul Lubock
    • Fred H. BurbankMichael L. JonesPaul Lubock
    • A61B1000
    • A61B10/0266A61B10/02A61B17/00491A61B17/32056A61B17/320725A61B17/3417A61B18/14A61B18/1487A61B18/1492A61B90/17A61B90/37A61B2017/3488A61B2018/00208A61B2018/00214A61B2018/00267A61B2018/00333A61B2018/00898A61B2018/0091A61B2018/00916A61B2018/1253A61B2018/126A61B2018/1407A61B2018/1475A61B2018/162A61B2090/3908
    • An apparatus and method are provided for precisely isolating a target lesion in a patient's body tissue, resulting in a high likelihood of“clean” margins about the lesion when it is removed for diagnosis and/or therapy. This approach advantageously will often result in the ability to both diagnose and treat a malignant lesion with only a single percutaneous procedure, with no follow-up percutaneous or surgical procedure required, while minimizing the risk of migration of possibly cancerous cells from the lesion to surrounding tissue or the bloodstream. In particular, the apparatus comprises a biopsy instrument having a distal end adapted for entry into the patient's body, a longitudinal shaft, and a cutting element disposed along the shaft. The cutting element is actuatable between a radially retracted position and a radially extended position. Advantageously, the instrument is rotatable about its axis in the radially extended position to isolate a desired tissue specimen from surrounding tissue by defining a peripheral margin about the tissue specimen. Once the tissue specimen is isolated, it may be segmented by further manipulation of the cutting element, after which the tissue segments are preferably individually removed from the patient's body through a cannula or the like. Alternatively, the specimen may be encapsulated and removed as an intact piece.
    • 提供了一种用于精确地分离患者体内组织中的靶病变的装置和方法,导致当其被去除用于诊断和/或治疗时,对病变的“清洁”边缘的高可能性。 这种方法有利地经常导致仅使用单一经皮手术来诊断和治疗恶性病变的能力,而不需要随访的经皮或外科手术,同时最小化可能的癌细胞从病变迁移到周围的风险 组织或血液。 特别地,该装置包括具有适于进入患者身体的远端的活检器械,纵向轴和沿轴设置的切割元件。 切割元件可在径向缩回位置和径向延伸位置之间致动。 有利地,仪器可以在其径向延伸位置中绕其轴线旋转,以通过围绕组织样本限定周边边缘来将期望的组织样本与周围组织隔离。 一旦组织样本被分离,则可以通过进一步操纵切割元件来分割组织样本,之后组织片段优选通过套管等从患者身体单独地移除。 或者,样品可以作为完整的片段被包封和去除。