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111. 发明申请

WO2017002126A1 SYSTEM AND METHOD FOR ANALYSIS OF FLUIDS FLOWING IN A CONDUIT 审中-公开
标题翻译：流体流动分析系统与方法
公开(公告)号：WO2017002126A1
公开(公告)日：2017-01-05
申请号：PCT/IL2016/050711
申请日：2016-07-03
申请人： ASPECT AI LTD.
发明人： RAPOPORT, Uri , SHAPIRA, Boaz
IPC分类号： G01N24/08 , G01R33/563 , G01N11/02
CPC分类号： G01N24/081 , G01N24/085 , G01R33/4835 , G01R33/563
摘要： System and method for analyzing changes in a fluid flowing through a conduit, including defining at least one coordinate within said conduit, said conduit having a first plurality of slices, receiving at least one known value for at least one property of the fluid, measuring said fluid using magnetic resonance, determining at least one image from the measured fluid, the at least one image having a second plurality of slices for said at least one coordinate, determining a second set of values for said at least one property of said fluid, comparing the first set of values and second set of values for said at least one property to determine a difference value, checking deviation of the determined difference from a predetermined value for said fluid, and issuing an alert if the deviation is not substantially zero.
摘要翻译：用于分析流过导管的流体的变化的系统和方法，包括限定所述导管内的至少一个坐标，所述导管具有第一多个切片，接收至少一个已知值用于流体的至少一个性质，测量所述使用磁共振的流体，从所测量的流体确定至少一个图像，所述至少一个图像具有用于所述至少一个坐标的第二多个切片，确定所述流体的所述至少一个性质的第二组值，比较所述至少一个属性的第一组值和第二组值用于确定差值，检查所确定的差异与所述流体的预定值的偏差，以及如果偏差基本上不为零则发出警报。

112. 发明申请

WO2016187146A1 COMPUTER-ACCESSIBLE MEDIUM FOR DETERMINING ARTERIAL INPUT FUNCTION 审中-公开
标题翻译：用于确定输入功能的计算机可访问介质
公开(公告)号：WO2016187146A1
公开(公告)日：2016-11-24
申请号：PCT/US2016/032756
申请日：2016-05-16
申请人： NEW YORK UNIVERSITY , ALBERT-LUDWIGS-UNIVERSITAT FREIBURG
发明人： NOVIKOV, Dmitry , JAHANI, Jeiran , KISELEV, Valerij G.
IPC分类号： A61B5/055 , A61B5/00 , A61B5/026 , A61B5/0275 , A61B5/029 , G01R33/563
CPC分类号： A61B5/055 , A61B5/00 , A61B5/0042 , A61B5/026 , A61B5/0275 , A61B5/029 , A61B8/065 , A61B2576/026 , G01R33/563 , G01R33/56366
摘要： An exemplary system, method and computer-accessible medium for determining an arterial input function (AIF) of a mammal(s) can be provided, which can include, for example, receiving information related to a global circulatory system of the mammal(s), and determining the AIF based on the information by modeling a blood flow in the global circulatory system of the mammal(s) in terms of an input response function(s). The input response function(s) can include a delayed input response function(s). In certain exemplary embodiments of the present disclosure, the input response function(s) can include at least three input response functions, and each of the input response functions can be from a different part of a body of the mammal(s). The AIF can be determined by coupling the input response functions. The AIF can be further determined based on a total tracer amount in an organ(s) of the mammal(s).
摘要翻译：可以提供用于确定哺乳动物的动脉输入功能（AIF）的示例性系统，方法和计算机可访问介质，其可以包括例如接收与哺乳动物的全球循环系统有关的信息，以及通过根据输入响应函数对所述哺乳动物的全球循环系统中的血流进行建模来基于所述信息来确定所述AIF。输入响应函数可以包括延迟的输入响应函数。在本公开的某些示例性实施例中，输入响应函数可以包括至少三个输入响应函数，并且每个输入响应函数可以来自哺乳动物身体的不同部分。 AIF可以通过耦合输入响应函数来确定。可以基于哺乳动物的器官中的总示踪剂量进一步确定AIF。

113. 发明申请

WO2016074946A1 MAGNETIC RESONANCE FINGERPRINTING IN SLICES ALONG A ONE-DIMENSIONAL EXTENSION 审中-公开
标题翻译：在一维延伸中指向单曲的磁共振
公开(公告)号：WO2016074946A1
公开(公告)日：2016-05-19
申请号：PCT/EP2015/075194
申请日：2015-10-30
申请人： KONINKLIJKE PHILIPS N.V.
发明人： AMTHOR, Thomas Erik , DONEVA, Mariya Ivanova , KOKEN, Peter , KEUPP, Jochen , BOERNERT, Peter
IPC分类号： G01R33/483 , G01R33/50 , A61B5/055 , G01R33/30 , G01R33/48 , G01R33/54
CPC分类号： A61B5/055 , A61B5/4872 , G01R33/307 , G01R33/4828 , G01R33/4835 , G01R33/50 , G01R33/54 , G01R33/563
摘要： The invention provides for a magnetic resonance imaging system (100) which comprise a magnet (104) and a magnetic field gradient generator (110, 112) for generating a gradient magnetic field within an imaging zone (108). The gradient magnetic field is aligned with a predetermined direction. The magnetic resonance imaging system further comprise a memory (134, 136) for storing machine executable instructions (150, 152, 154), a pre-calculated magnetic resonance fingerprinting dictionary (144), and pulse sequence instructions (140). The pulse sequence instructions cause the magnetic resonance imaging system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting technique. The magnetic resonance fingerprinting technique encodes the magnetic resonance data as slices (125). The pre-calculated magnetic resonance fingerprinting dictionary contains a listing of calculated magnetic resonance signals in response to execution of the pulse sequence instructions for a set of predetermined substances. Execution of the machine executable instructions causes a processor (130) controlling the magnetic resonance imaging system to: acquire (300) the magnetic resonance data by controlling the magnetic resonance imaging system with pulse sequence instructions; divide (302) the magnetic resonance data into a set of slices; calculate (304) the abundance of each of the set of predetermined substances within each of the set of slices by comparing the magnetic resonance data for each of the set of slices with the pre-calculated magnetic resonance fingerprinting dictionary; and calculate (306) amagnetic resonance fingerprint chart by plotting abundance of each of the set of predetermined substances within each of the set of slicesas a function of position along the predetermined direction.
摘要翻译：本发明提供一种磁共振成像系统（100），其包括用于在成像区域（108）内产生梯度磁场的磁体（104）和磁场梯度发生器（110,112）。梯度磁场与预定方向对齐。磁共振成像系统还包括用于存储机器可执行指令（150,152,154），预先计算的磁共振指纹词典（144）和脉冲序列指令（140）的存储器（134,136）。脉冲序列指令使得磁共振成像系统根据磁共振指纹技术获取磁共振数据。磁共振指纹技术将磁共振数据编码为片（125）。预先计算的磁共振指纹词典包含响应于一组预定物质的脉冲序列指令的执行而计算的磁共振信号的列表。执行机器可执行指令使得控制磁共振成像系统的处理器（130）通过用脉冲序列指令控制磁共振成像系统来获取（300）磁共振数据; 将（302）磁共振数据划分成一组切片; 通过将所述一组切片中的每一个的磁共振数据与所述预先计算的磁共振指纹词典进行比较，来计算（304）所述一组切片中的每组中的所述一组预定物质的丰度; 并且通过绘制在所述一组切片中的每组中的所述一组预定物质中的每一个的丰度作为沿着所述预定方向的位置的函数来计算（306）磁共振指纹图。

114. 发明申请

WO2016072581A1 MEDICAL IMAGING APPARATUS AND METHOD OF PROCESSING MEDICAL IMAGE 审中-公开
标题翻译：医学影像设备及医疗图像处理方法
公开(公告)号：WO2016072581A1
公开(公告)日：2016-05-12
申请号：PCT/KR2015/006676
申请日：2015-06-30
申请人： SAMSUNG ELECTRONICS CO., LTD.
发明人： JO, Hyun-hee , KIM, Dae-hwan , KIM, Joon-soo , JUNG, Sung-pil , CHOI, Yang-lim
IPC分类号： A61B5/055
CPC分类号： G01R33/5608 , G01R33/4835 , G01R33/546 , G01R33/563 , G01R33/56325
摘要： Provided are a medical imaging apparatus and method of processing a medical image. The medical imaging apparatus includes: an output unit configured to display in a first region of a screen a magnetic resonance (MR) image matrix in which a plurality of MR images obtained by performing magnetic resonance imaging (MRI) of a heart are arranged; and an image processor configured to display at least one indicator which indicates a column of the MR image matrix representing at least one of end diastole and end systole and display at least one mark in a row of the MR image matrix which indicates MR images respectively corresponding to an apex and a base of the heart.
摘要翻译：提供了一种医疗成像装置和医疗图像的处理方法。医疗成像装置包括：输出单元，被配置为在屏幕的第一区域显示磁共振（MR）图像矩阵，其中通过进行心脏的磁共振成像（MRI）获得的多个MR图像被布置; 以及图像处理器，被配置为显示至少一个指示符，所述至少一个指示符指示MR图像矩阵的列，其表示舒张末端和末端收缩末端中的至少一个，并且在MR图像矩阵的一行中显示分别对应于MR图像的MR图像中的至少一个标记到心脏的顶点和基部。

115. 发明申请

WO2011021175A2 SYSTEM AND METHOD FOR ANALYZING IMAGING DATA 审中-公开
标题翻译：用于分析成像数据的系统和方法
公开(公告)号：WO2011021175A2
公开(公告)日：2011-02-24
申请号：PCT/IL2009/000847
申请日：2009-09-01
申请人： BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY , FRIEDMAN, Alon , CHASSIDIM, Yoash , PRAGER, Ofer , SHELEF, Ilan
发明人： FRIEDMAN, Alon , CHASSIDIM, Yoash , PRAGER, Ofer , SHELEF, Ilan
IPC分类号： G06T7/00
CPC分类号： G06T7/0016 , A61B3/0025 , A61B3/1241 , A61B5/0059 , A61B5/0263 , A61B5/0275 , A61B5/4064 , A61B5/7207 , A61B6/037 , A61B6/501 , A61B6/507 , A61B6/5217 , A61B8/06 , A61B8/5223 , G01R33/5608 , G01R33/563 , G01R33/5635 , G06T2207/10064 , G06T2207/10096 , G06T2207/30016 , G06T2207/30041 , G06T2207/30104
摘要： A method of analyzing a stream of imaging data is disclosed. The method comprises: for each picture-element of the data, associating a vector of features indicative of temporal intensity variation relative to baseline intensity, thereby providing a plurality of vectors. The method further comprises clustering the picture-elements according to the vectors, thereby providing a plurality of clusters, and identifying different compartments in the vasculature based on the clusters.
摘要翻译：公开了一种分析成像数据流的方法。该方法包括：对于数据的每个图像元素，将指示相对于基线强度的时间强度变化的特征矢量相关联，由此提供多个矢量。该方法还包括根据矢量对图像元素进行聚类，从而提供多个聚类，并且基于聚类识别脉管系统中的不同隔室。

116. 发明申请

WO2010104855A3 APPARATUS AND METHOD FOR MAGNETIC RESONANCE IMAGING WITH HIGH SPATIAL AND TEMPORAL RESOLUTIONS 审中-公开
标题翻译：具有高空间和时间分辨率的磁共振成像装置和方法
公开(公告)号：WO2010104855A3
公开(公告)日：2011-01-13
申请号：PCT/US2010026666
申请日：2010-03-09
申请人： UNIV JOHNS HOPKINS , US GOV HEALTH & HUMAN SERV , HERZKA DANIEL ALFREDO , DERBYSHIRE JOHN ANDREW
发明人： HERZKA DANIEL ALFREDO , DERBYSHIRE JOHN ANDREW
IPC分类号： A61B5/055
CPC分类号： G01R33/563 , A61B5/0205 , A61B5/0402 , A61B5/055 , A61B5/08 , A61B5/1102 , A61B5/113 , A61B5/4836 , A61B5/7207 , A61B5/7257 , A61B5/7285 , A61B18/20 , A61B2018/00577 , A61B2018/00994 , A61B2576/00 , G01R33/36 , G01R33/385 , G01R33/4808 , G01R33/4824 , G01R33/56308 , G01R33/56325 , G01R33/5676
摘要： A magnetic resonance imaging (MRI) system, comprising a magnetic resonance imaging scanner. The MR scanner comprises a main magnet providing a substantially uniform main magnetic field B0 for a subject under observation, the subject represented by a spatial distribution of magnetizations; a radio frequency (RF) coil system configured to irradiate a plurality of radio frequency (RF) pulses into a region of interest of the subject and to detect a plurality of RF response signals emitted from the region of interest; a gradient coil system configured to provide a perturbation of the main magnetic field B0 using a gradient pulse sequence that causes the RF response signals to encode the spatial distribution of magnetizations in a Fourier domain on a plurality of read-out paths; and a controller in communication with the RF coil system and the gradient coil system to synchronously provide the RF coil system with the plurality of RF pulses and the gradient coil system with the gradient pulse sequence. The gradient pulse sequence comprises a navigator pulse that causes one of the plurality of RF response signals to encode the spatial distribution of magnetizations in the Fourier domain on a pre-determined navigator path that represents a fixed projection of the region of interest of the subject, the pre-determined navigator path is suitable to be in a direction different from directions of the read-out paths, and the fixed projection of the subject is capable of tracking a motion of the subject.
摘要翻译：磁共振成像（MRI）系统，包括磁共振成像扫描仪。 MR扫描仪包括主磁体，为观察对象提供基本上均匀的主磁场B0，该对象由磁化的空间分布表示; 射频（RF）线圈系统，被配置为将多个射频（RF）脉冲照射到所述对象的感兴趣区域中并且检测从所述感兴趣区域发射的多个RF响应信号; 梯度线圈系统，被配置为使用梯度脉冲序列来提供主磁场B0的扰动，所述梯度脉冲序列使RF响应信号在多个读出路径上的傅立叶域中的磁化空间分布进行编码; 以及与RF线圈系统和梯度线圈系统通信的控制器，以使RF线圈系统同时向梯形线圈系统提供具有梯度脉冲序列的多个RF脉冲和梯度线圈系统。梯度脉冲序列包括导航器脉冲，其导致所述多个RF响应信号中的一个RFF响应信号将傅立叶域中的磁化的空间分布编码在预定导航器路径上，所述预定导航器路径表示所述对象感兴趣区域的固定投影，预定导航器路径适合于与读出路径的方向不同的方向，并且被摄体的固定投影能够跟踪被摄体的运动。

117. 发明申请

WO2009134820A2 TOOL FOR ACCURATE QUANTIFICATION IN MOLECULAR MRI 审中-公开
标题翻译：用于精确定量分析MRI的工具
公开(公告)号：WO2009134820A2
公开(公告)日：2009-11-05
申请号：PCT/US2009042005
申请日：2009-04-28
申请人： UNIV CORNELL , WANG YI , DE ROCHEFORT LUDOVIC , KRESSLER BRYAN , LIU TIAN , SPINCEMAILLE PASCAL
发明人： WANG YI , DE ROCHEFORT LUDOVIC , KRESSLER BRYAN , LIU TIAN , SPINCEMAILLE PASCAL
IPC分类号： G01R33/28 , G01R33/54 , G01R33/563
CPC分类号： G01R33/54 , G01R33/5601 , G01R33/5608 , G01R33/563
摘要： A method and apparatus is provided for magnetic source magnetic resonance imaging. The method includes collecting energy signals from an object, providing additional information of characteristics of the object, and generating the image of the object from the energy signals and from the additional information such that the image includes a representation of a quantitative estimation of the characteristics. The additional information may comprise predetermined characteristics of the object, a magnitude image generated from the object, or magnetic signals collected from different relative orientations between the object and the imaging system. The image is generated by an inversion operation based on the collected signals and the additional information. The inversion operation minimizes a cost function obtained by combining the data extracted from the collected signals and the additional information of the object. Additionally, the image is used to detect a number of diagnostic features including microbleeds, contract agents and the like.
摘要翻译：提供了用于磁源磁共振成像的方法和装置。该方法包括从对象收集能量信号，提供对象的特征的附加信息，以及从能量信号和附加信息生成对象的图像，使得图像包括特征的定量估计的表示。附加信息可以包括对象的预定特征，从对象产生的幅度图像，或从物体和成像系统之间的不同相对取向收集的磁信号。通过基于收集的信号和附加信息的反转操作来生成图像。反转操作最小化通过组合从所收集的信号提取的数据和对象的附加信息而获得的成本函数。此外，该图像用于检测多个诊断特征，包括微出血，合同代理等。

118. 发明申请

WO2007142636A1 FLUID TYPING 审中-公开
标题翻译：流体型
公开(公告)号：WO2007142636A1
公开(公告)日：2007-12-13
申请号：PCT/US2006/021973
申请日：2006-06-06
申请人： HALLIBURTON ENERGY SERVICES, INC. , FRANSSON, Carl-Magnus , CHERRY, Ronald, E.
发明人： FRANSSON, Carl-Magnus , CHERRY, Ronald, E.
IPC分类号： G01V3/00 , G01R33/20
CPC分类号： G01V3/32 , G01N24/08 , G01N24/081 , G01R33/50 , G01R33/5617 , G01R33/563 , G01R33/56341
摘要： In some embodiments, apparatus and systems, as well as methods, may operate to acquire data representing a plurality of nuclear magnetic resonance (NMR) echo trains associated with a material, such as a geological formation. Additional operations may include inverting a model of at least one of the plurality of NMR echo trains to provide an estimated distribution of transverse relaxation time constants, inverting models of selected ones of the plurality of NMR echo trains using the estimated distribution of transverse relaxation time constants to provide an estimated diffusion distribution, and inverting a model of selected ones of the plurality of NMR echo trains, using the estimated distributions of transverse relaxation time constants and diffusion, to provide an apparent and an intrinsic probability density function to identify fluid types in the material.
摘要翻译：在一些实施例中，装置和系统以及方法可以操作以获取表示与诸如地质构造的材料相关联的多个核磁共振（NMR）回波列的数据。附加操作可以包括颠倒多个NMR回波列中的至少一个的回波序列的模型，以提供横向弛豫时间常数的估计分布，使用估计的横向弛豫时间常数分布来反演多个NMR回波列中所选择的一个NMR回波列的模型以提供估计的扩散分布，并且使用估计的横向弛豫时间常数和扩散的分布来反转多个NMR回波列中的选定的一个的回波序列的模型，以提供明显的和固有的概率密度函数来识别材料。

119. 发明申请

WO2006002412A2 MOVING TARGET MAGNETIC RESONANCE IMAGING SYSTEM AND METHOD 审中-公开
标题翻译：移动目标磁共振成像系统和方法
公开(公告)号：WO2006002412A2
公开(公告)日：2006-01-05
申请号：PCT/US2005/022669
申请日：2005-06-28
申请人： PEDIATRIC IMAGING TECHNOLOGY, LLC , BENZ, Mark, G. , BENZ, Matthew, W.
发明人： BENZ, Mark, G. , BENZ, Matthew, W.
IPC分类号： G01V3/00
CPC分类号： G01R33/563
摘要： A system and method for imaging an object that takes into account movement of the object in producing an MR image. A system may include a target volume location sensor for determining a location of an object being imaged. A moving-target algorithm may use the location information and other image information to match appropriate data to construct an image of the object. A moving-target algorithm may use the location information to provide instruction on changing a gradient field of an imaging system to account for a location of an object.
摘要翻译：一种用于成像对象的系统和方法，其考虑了在产生MR图像中物体的移动。系统可以包括用于确定被成像物体的位置的目标体积位置传感器。移动目标算法可以使用位置信息和其他图像信息来匹配适当的数据来构建对象的图像。移动目标算法可以使用位置信息来提供关于改变成像系统的梯度场以指示对象的位置的指令。

120. 发明申请

WO2005001501A1 BACKGROUND SUPPRESSION METHOD FOR TIME-RESOLVED MAGNETIC RESONANCE ANGIOGRAPHY 审中-公开
标题翻译：背景抑制时间分辨率磁共振成像方法
公开(公告)号：WO2005001501A1
公开(公告)日：2005-01-06
申请号：PCT/US2004/017929
申请日：2004-06-07
申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION , BLOCK, Walter , ARUNACHALAM, Arjun
发明人： BLOCK, Walter , ARUNACHALAM, Arjun
IPC分类号： G01R33/563
CPC分类号： G01R33/5601 , G01R33/563
摘要： A 3D projection reconstruction pulse sequence is employed during a CEMRA dynamic study to acquire a time course series of k-space data sets. Signals from non-vascular voxels are suppressed by reconstructing a corresponding series of low resolution images using the centers of the acquired k-space data sets, and measuring the degree to which the signal behavior of voxels therein differ from a model of unwanted signal. Signals from voxels which do not differ from the model are suppressed and the resulting filtered low resolution images are transformed back to k-space and combined with the originally acquired peripheral k-space data to form complete, filtered k-space data sets from which images may be reconstructed.
摘要翻译：在CEMRA动态研究期间采用3D投影重建脉冲序列来获取k空间数据集的时间序列。通过使用所获取的k空间数据集的中心重建相应的一系列低分辨率图像，并且测量其中的体素的信号行为与不想要的信号的模型的程度来抑制来自非血管体素的信号。来自与模型没有不同的体素的信号被抑制，并且所得到的经滤波的低分辨率图像被转换回到k空间并与原始获取的外围k空间数据组合以形成完整的，经滤波的k空间数据集，可以重建。

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