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101. 发明申请

US20070284548A1 Particle therapy plan and method for compensating for an axial deviation in the position of a particle beam of a particle therapy system 审中-公开
标题翻译：用于补偿颗粒治疗系统的粒子束位置的轴向偏差的粒子治疗计划和方法
公开(公告)号：US20070284548A1
公开(公告)日：2007-12-13
申请号：US11717558
申请日：2007-03-12
申请人： Werner Kaiser , Vitali Lazarev , Heiko Rohdjess
发明人： Werner Kaiser , Vitali Lazarev , Heiko Rohdjess
IPC分类号： H01J29/02
CPC分类号： A61N5/01 , A61N5/1049 , A61N5/1081 , A61N2005/1085
摘要： A particle therapy system is provided. The particle therapy system includes a rotatable gantry being operable to generate a particle beam during operation and a measuring instrument for determining a position of the particle beam. The gantry is movable in the axial direction to correct a deviation in the position of the particle beam from an axial set-point position.
摘要翻译：提供了一种粒子治疗系统。粒子治疗系统包括可操作以在操作期间产生粒子束的可旋转机架和用于确定粒子束位置的测量仪器。台架可沿轴向移动以校正粒子束从轴向设定点位置的位置的偏差。

102. 发明授权

US06487274B2 X-ray target assembly and radiation therapy systems and methods 有权
公开(公告)号：US06487274B2
公开(公告)日：2002-11-26
申请号：US09772435
申请日：2001-01-29
申请人： Kirk Joseph Bertsche
发明人： Kirk Joseph Bertsche
IPC分类号： H01J3510
CPC分类号： H01J35/08 , A61N5/10 , A61N2005/1085 , H01J2235/081
摘要： A multi-region target that is configured to selectively generate two different energy distributions when exposed to an excitation electron beam is described. The multi-region target includes multiple regions with different x-ray generating characteristics. Thus, the interaction between an excitation electron beam and the target generates an x-ray beam with an energy distribution that depends upon which target region is exposed to the excitation electron beam. The different x-ray spectra may be used to produce an enhanced contrast x-ray image. A method of detecting the rotational position of the multi-region target based upon the contrast level of the resulting images also is described.

103. 发明申请

US20020168048A1 METHOD FOR PRODUCING A RANGE OF THERAPEUTIC RADIATION ENERGY LEVELS 失效
标题翻译：生产治疗放射能量范围的方法
公开(公告)号：US20020168048A1
公开(公告)日：2002-11-14
申请号：US09805536
申请日：2001-03-13
发明人： James R. Wong , Chee-Wai Cheng
IPC分类号： A61N005/10
CPC分类号： A61N5/10 , A61N2005/1085
摘要： The present invention provides a method for producing a broad range of therapeutic radiation energy levels with a source of radiation that is operated to produce photons or particles at a first energy that are directed at a treatment site for a predetermined absorbed dose. The linear accelerator is then operated to produce photons or particles at a second energy directed at the treatment site for another predetermined absorbed dose. The appropriate selection of the first and second absorbed doses yields an absorbed dose at the treatment site equivalent to the dose produced by photons having an energy that is intermediate of the first and second energies. Thus, a dual energy linear accelerator may be operated according to the method to yield a continuous range of energies.
摘要翻译：本发明提供了一种用于产生具有辐射源的宽范围的治疗辐射能级的方法，所述辐射源被操作以产生以指定于治疗部位预定吸收剂量的第一能量的光子或颗粒。然后操作线性加速器以在针对治疗部位的第二能量产生另一预定吸收剂量的光子或颗粒。第一和第二吸收剂量的适当选择在治疗部位产生相当于具有第一和第二能量中间能量的光子产生的剂量的吸收剂量。因此，可以根据该方法操作双能量线性加速器以产生连续的能量范围。

104. 发明授权

US5866912A System and method for multiple particle therapy 失效
标题翻译：多粒子治疗的系统和方法
公开(公告)号：US5866912A
公开(公告)日：1999-02-02
申请号：US25992
申请日：1998-02-19
申请人： James M. Slater , Daniel W. Miller , Jon W. Slater
发明人： James M. Slater , Daniel W. Miller , Jon W. Slater
IPC分类号： A61N5/10 , H01J37/30 , H05H3/00
CPC分类号： A61N5/10 , A61N2005/1085 , A61N2005/1087 , A61N2005/109 , A61N2005/1095
摘要： A system for delivering two types of particles to a target within the body of a patient. A proton beam therapy system produces a beam of protons that is directed from a nozzle towards a target isocenter located within the body of a patient. The beam of protons can pass directly to the patient or pass through a neutron source comprised of a plate of neutron-rich material. Collisions between some of the protons and neutrons cause neutrons to be emitted from the material thereby generating a multiple particle beam comprised of both protons and neutrons. Preferably, the neutrons comprise only a small percent of the total particles in the beam. In the preferred embodiment, the neutron source is comprised of a plate of Beryllium that is interposed between the nozzle and the patient.
摘要翻译：用于将两种类型的颗粒递送到患者体内的靶标的系统。质子束治疗系统产生质子束，其从喷嘴朝向位于患者体内的目标等角点引导。质子束可以直接传递到患者身上或穿过由富含中子的材料组成的中子源。一些质子和中子之间的碰撞使中子从材料中发射，从而产生由质子和中子两者组成的多个粒子束。优选地，中子仅占波束中总体颗粒的一小部分。在优选实施例中，中子源包括介于喷嘴和患者之间的铍板。

105. 发明授权

US5274689A Tunable gamma ray source 失效
标题翻译：可调伽马射线源
公开(公告)号：US5274689A
公开(公告)日：1993-12-28
申请号：US988752
申请日：1992-12-10
申请人： Jose C. Palathingal , Kelvin G. Lynn , Palakkal Asoka-Kumar
发明人： Jose C. Palathingal , Kelvin G. Lynn , Palakkal Asoka-Kumar
IPC分类号： A61N5/10 , H05H6/00 , H01J35/00
CPC分类号： A61N5/10 , H05H6/00 , A61N2005/1085
摘要： A source of gamma rays (a photon beam) at a single energy produced by the single-quantum annihilation of accelerated positrons with electrons of a target element. The photons are emitted predominantly in the forward direction and are accompanied by background radiation which can be differentially suppressed. The energy of the photons is determined by varying the energy of incident positrons. The photon beam is usable in materials research and analysis, medical diagnosis and therapy, and numerous other fields.
摘要翻译：在单个能量产生的γ射线（光子束）源，其通过具有目标元素的电子的加速正电子的单量子湮灭而产生。光子主要以向前的方向发射并且伴随有可被差异抑制的背景辐射。通过改变入射正电子的能量来确定光子的能量。光子束可用于材料研究与分析，医学诊断和治疗等众多领域。

107. 发明专利

JP4467389B2 Sterilization method and sterilization equipment 有权
标题翻译：空值
公开(公告)号：JP4467389B2
公开(公告)日：2010-05-26
申请号：JP2004262862
申请日：2004-09-09
申请人：シャープ株式会社
发明人：久晴八木 , 善弘清水 , 和男西川 , 藍馬場
IPC分类号： A61L2/02 , A61L2/18
CPC分类号： A61L2/0011 , A61L2/14 , A61N2005/1085

108. 发明专利

JP2007503967A Field configuration with reduced divergence 审中-公开
公开(公告)号：JP2007503967A
公开(公告)日：2007-03-01
申请号：JP2006533293
申请日：2004-05-20
申请人：ライフェルレナード
发明人：ライフェル、レナード
IPC分类号： A61N5/10 , A61N2/00 , A61N2/02 , G21K1/093
CPC分类号： A61N5/1042 , A61N2/002 , A61N2/02 , A61N2005/1085 , G21K1/093
摘要：光子ビームの線量増強が、第１の磁石の第１の中心磁界ベクトルが第２の磁石の第２の中心磁界ベクトルに平行であるよりむしろ逆平行であるように、少なくとも２つの磁石を互い違いに対置されたコイル構成に構成することで制御されている。ある形式では、第１の磁石の第１の中心磁界ベクトルが第２の磁石の第２の中心磁界ベクトルに対し±９０°〜±１８０°の範囲で回転されている。典型的に、第１の中心磁界ベクトルは第２の中心磁界ベクトルと同軸でない。結果としての磁界構成が、対象となっている身体の深部に到達可能な磁界の絶対値の大きい部分をより広く有し、絶対値の大きい領域内部に身体の広い部分を収容できる付加的な空間を供給する。

109. 发明专利

JP2006075358A Sterilization method and sterilizer 有权
标题翻译：灭菌方法和杀菌剂
公开(公告)号：JP2006075358A
公开(公告)日：2006-03-23
申请号：JP2004262862
申请日：2004-09-09
申请人： Sharp Corp , シャープ株式会社
发明人： BABA AI , NISHIKAWA KAZUO , YAGI HISAHARU , SHIMIZU YOSHIHIRO
IPC分类号： A61L2/02 , A61L2/14 , A61L2/18
CPC分类号： A61L2/0011 , A61L2/14 , A61N2005/1085
摘要： PROBLEM TO BE SOLVED: To provide a new sterilization method and a sterilizer which show an effect against all the microbes or viruses, and which are safe to a living body to be sterilized. SOLUTION: The sterilization method characteristically fragmentates proteins of the microbes or viruses on condition that nucleic acids of the microbes or viruses are not destroyed by releasing particles having reacting properties to the microbes or viruses. The sterilizer sterilizes the microbes or viruses in an object by releasing air containing the particles having the reacting properties for fragmentating the proteins without breaking the nucleic acids. COPYRIGHT: (C)2006,JPO&NCIPI

110. 发明申请

WO2015189603A1 ASSEMBLY, APPARATUS, SYSTEM AND METHOD 审中-公开
标题翻译：装配，装置，系统和方法
公开(公告)号：WO2015189603A1
公开(公告)日：2015-12-17
申请号：PCT/GB2015/051692
申请日：2015-06-09
申请人： UNIVERSITY OF LINCOLN
发明人： ALLINSON, Nigel , RILEY, Grainne , WALTHAM, Chris , ESPOSITO, Michela , PRICE, Tony , ALLPORT, Phil , TAYLOR, Jon , CASSE, Gianluigi , EVANS, Phil , POLUDNIOWSKI, Gavin , GREEN, Stuart , MANOLOPOULOS, Spyros , NIETO-CAMERO, Jaime , VERHOEVEN, Marcus
IPC分类号： A61N5/10
CPC分类号： A61N5/1071 , A61B6/032 , A61B6/4064 , A61B6/4241 , A61B6/4258 , A61B6/4266 , A61N5/1077 , A61N2005/1054 , A61N2005/1085 , A61N2005/1087 , G01T1/02 , G01T1/2928 , G01T1/2985
摘要： Some embodiments of the present invention provide apparatus having a particle beamline for passage of charged particles of radiation therealong, comprising: a first beam tracker structure comprising at least one position sensitive detector (PSD) for determining a location with respect to a cross-sectional area of the beam line at which particles pass through the PSD; energy discrimination apparatus for determining an energy of particles that have passed through the first beam tracker structure; and support means for supporting a subject in a path of a particle along the beamline between the first beam tracker structure and the energy discrimination apparatus, the apparatus being configured to be operated in a selected one of a first mode and a second mode, the apparatus being configured, in the first mode of operation, to control an energy of the beam of charged particles passing through the first beam tracker structure such that a Bragg peak of charged particle absorption is located within the subject, and in the second mode of operation, to control an energy of the beam of charged particles passing through the first beam tracker structure such that a Bragg peak of charged particle absorption is located within the energy discrimination apparatus.
摘要翻译：本发明的一些实施例提供具有粒子束线的装置，该粒子束线用于沿其上的带电粒子的通过，包括：第一光束跟踪器结构，包括至少一个位置敏感检测器（PSD），用于确定相对于横截面积的位置的粒子通过PSD的束线; 用于确定通过第一光束跟踪器结构的颗粒的能量的能量鉴别装置; 以及支撑装置，用于支撑沿着第一光束跟踪器结构和能量判别装置之间的束线的粒子路径中的对象，该装置被配置为以第一模式和第二模式中的选定的一个操作，该装置在第一操作模式中，控制通过第一光束跟踪器结构的带电粒子束的能量，使得带电粒子吸收的布拉格峰位于被摄体内，而在第二操作模式中，以控制通过第一光束跟踪器结构的带电粒子束的能量，使得带电粒子吸收的布拉格峰位于能量鉴别装置内。

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