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    • 101. 发明申请
    • Cell Sensor, And Monitoring Method Using Same For The Real-Time Monitoring Of Cell Capacitance
    • 细胞传感器和使用相同的监测方法进行细胞电容的实时监测
    • US20120064513A1
    • 2012-03-15
    • US13264096
    • 2010-04-07
    • Kyung Hwa YooChae Ok YunDong Hyun KimRi Mi LeeKyu Jung KimPyung Hwan Kim
    • Kyung Hwa YooChae Ok YunDong Hyun KimRi Mi LeeKyu Jung KimPyung Hwan Kim
    • C12Q1/70G01N27/22C12Q1/02C12M1/34
    • C12Q1/02G01N33/54373
    • The present invention relates to a cell sensor for real-time monitoring of cell capacitance and a monitoring method using the same, and more particularly, to a cell sensor capable of monitoring an endocytosis process of a biomolecule through a cell surface receptor by attaching a cell between electrodes and then measuring in real time the capacitance between the electrodes over time, and a monitoring method using the same. A cell sensor for the real-time monitoring of cell capacitance according to an exemplary embodiment of the present invention includes a substrate; a first electrode and a second electrode that are formed on the substrate and spaced apart by a gap from each other, in which at least one or more cells are introduced to be attached onto the gap; and a passivation layer that is formed on each of the tops of the first electrode and the second electrode to prevent the cells from being attached onto the top of the first electrode and the second electrode. The cell sensor for the real-time monitoring of cell capacitance and the method for real-time monitoring of the cell condition using the same according to an exemplary embodiment of the present invention have the effect of being able to monitor an endocytosis process of a biomolecule through a cell surface receptor in real time, by attaching cells having a receptor for the particular biomolecule between electrodes and then measuring in real time the capacitance between the electrodes over time.
    • 本发明涉及一种用于实时监测细胞电容的细胞传感器和使用该细胞电容的监测方法,更具体地说,涉及能够通过细胞表面受体监测生物分子的内吞过程的细胞传感器 在电极之间,然后实时测量电极之间的电容随时间的变化,以及使用其的监测方法。 根据本发明的示例性实施例的用于实时监测单元电容的单元传感器包括基板; 第一电极和第二电极,其形成在基板上并且彼此间隔开间隔开,其中至少一个或多个电池被引入以附着到间隙上; 以及钝化层,形成在第一电极和第二电极的每个顶部上,以防止电池附着在第一电极和第二电极的顶部上。 根据本发明的示例性实施方式,用于实时监测细胞电容的细胞传感器和用于实时监测细胞状态的方法具有能够监测生物分子的内吞过程的效果 通过在电极之间附着具有用于特定生物分子的受体的细胞,然后实时测量电极之间的电容,实时地通过细胞表面受体。
    • 102. 发明授权
    • Coupling channel noise canceling circuit
    • 耦合通道噪声消除电路
    • US08107568B2
    • 2012-01-31
    • US12402622
    • 2009-03-12
    • Dong Hyun KimYong Woon Park
    • Dong Hyun KimYong Woon Park
    • H03D1/04
    • H04B1/123H04B1/3805H04B1/525
    • A coupling channel noise canceling circuit includes a signal detecting unit, a gain setting unit, a cancel signal generating unit, and a noise canceling unit. The signal detecting unit detects a phase difference and a voltage difference between a broadcast RX signal and a noise cancel signal in a set mode. The gain setting unit outputs compensation gain values corresponding to the phase difference and the voltage difference from the signal detecting unit in the set mode. The cancel signal generating unit sets the compensation gain values from the gain setting unit as an amplification gain for amplification of a communication TX signal in the set mode, and amplifies the communication TX signal by a predetermined gain to generate the noise cancel signal in the set mode and an operation mode. The noise canceling unit cancels an interference noise from the broadcast RX signal by using the noise cancel signal from the cancel signal generating unit in the operation mode.
    • 耦合通道噪声消除电路包括信号检测单元,增益设置单元,消除信号产生单元和噪声消除单元。 信号检测单元在设定模式下检测广播RX信号和噪声消除信号之间的相位差和电压差。 增益设定单元在设定模式下输出与信号检测单元的相位差和电压差对应的补偿增益值。 消除信号生成单元将来自增益设定单元的补偿增益值设定为在设定模式下的通信TX信号的放大的放大增益,并且将通信TX信号放大预定的增益以产生该组中的噪声消除信号 模式和操作模式。 噪声消除单元通过在操作模式中使用来自消除信号生成单元的噪声消除信号来消除来自广播RX信号的干扰噪声。