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    • 91. 发明申请
    • Magnetic gradient field projection
    • 磁梯度场投影
    • US20040263170A1
    • 2004-12-30
    • US10824653
    • 2004-04-15
    • BTG International Limited,
    • Peter Gordon MorrisAbdullah Hussien Jamea
    • G01V003/00
    • G01R33/3808G01N24/084G01R33/385G01R33/441G01R33/4831
    • The invention relates to the projection of magnetic gradient fields for use in Magnetic Resonance Imaging. The projection of a gradient outside of a field generating assembly allows imaging of samples which will not physically fit inside the coil confines. An apparatus and method for improving the linearity of the projected gradient field is disclosed. This is achieved by arranging the position of the magnetic field generating coil conductors such that the second derivative of a gradient component is equal to zero. In one practical example the linearity is improved by providing a first circular coil which is positioned so that its centre is offset along the axis of the field generating coil assembly by a distance equal to half the radius of the coil. In another example a pair of current carrying wires are selectively positioned offset from a region of interest.
    • 本发明涉及用于磁共振成像的磁梯度场的投影。 场产生组件外部的梯度的投影允许对物理上不适合线圈限制的样本的成像。 公开了一种用于提高投影梯度场的线性度的装置和方法。 这是通过布置磁场产生线圈导体的位置使得梯度分量的二阶导数等于零来实现的。 在一个实际的例子中,通过提供第一圆形线圈来提高线性度,该第一圆形线圈被定位成使得其中心沿着场产生线圈组件的轴线偏移距离等于线圈半径的距离。 在另一示例中,一对载流导线选择性地定位为偏离感兴趣区域。
    • 92. 发明申请
    • Two dimensional B1-gradient NMR imager
    • 二维B1梯度NMR成像仪
    • US20030020474A1
    • 2003-01-30
    • US10156174
    • 2002-05-28
    • THE UNIVERSITY OF CHICAGO
    • Rex E. Gerald IIRafael L. GreenblattJerome W. Rathke
    • G01V003/00
    • G01R33/307G01R33/4831
    • A two dimensional B1-gradient NMR imager and methods for non-invasive spectroscopic investigations and imaging of the internal distribution and speciation of materials of fluid, solid, and semisolid objects in two spatial dimensions utilizing a toroid cavity detector. An RF signal transmitter/receiver generates a magnetic field B1 within the toroid cavity and receives a sample response to the magnetic fields B0 and B1. A pivot angle position controller adjusts a pivot angle position of the toroid cavity and enclosed sample to vary an angle between the magnetic field B0 and the central axis of said toroid cavity. A positional rotation controller positions the toroid cavity and enclosed sample at variable angular orientations relative to an initial position and a plane formed by the externally applied static main magnetic field B0 and the central axis of the toroid cavity. A computer sequentially receives and processes sample responses to produce a two-dimensional image.
    • 二维B1梯度NMR成像仪和非侵入性光谱研究的方法,以及利用环形腔检测器在两个空间维度中对流体,固体和半固体物质的内部分布和物质形态的成像。 RF信号发射器/接收器在环形腔内产生磁场B1,并接收对磁场B0和B1的采样响应。 枢转角位置控制器调节环形腔和封闭样品的枢转角度位置,以改变磁场B0和所述环形腔的中心轴线之间的角度。 位置旋转控制器将环形腔和封闭样品相对于初始位置和由外部施加的静态主磁场B0和环形腔的中心轴形成的平面以可变的角度取向定位。 计算机顺序地接收并处理样本响应以产生二维图像。
    • 93. 依法登记的发明
    • NMR imaging with varying spatial coupling
    • USH1218H
    • 1993-08-03
    • US818939
    • 1992-05-06
    • David G. CoryJoel B. MillerAllen N. Garroway
    • David G. CoryJoel B. MillerAllen N. Garroway
    • G01R33/483
    • G01R33/4831
    • A method for obtaining a nuclear magnetic resonance image of a sample is performed by first placing the sample in a homogeneous static magnetic field excited with a homogeneous transmitter device. Spin magnetization in the sample is thus initially detected with an inhomogeneous receiver device such that an induced voltage in the receiver device depends on a spatial location of precessing nuclei in the sample. Then, a spatial coupling of the sample and the receiver device is varied and the spin magnetization in the sample is again detected with the inhomogeneous receiver device. The full spatial distribution of the spin density of the sample and hence an image of the sample is then determined with the spin magnetizations detected. Either the sample is moved relative to the receiver device, or the spatial coupling of the receiver device and the sample is electronically altered. Any spin interactions are eliminated by using coherent averaging techniques before the detecting steps. In addition, during the varying step, the spin magnetization is either: left in the transverse plane; stored along the static magnetic field direction; allowed to equilibrate along the static magnetic field direction; or spin locked.
    • 95. 发明授权
    • NMR spectroscopy body probes with at least one surface coil
    • 具有至少一个表面线圈的NMR光谱体探针
    • US4636730A
    • 1987-01-13
    • US641540
    • 1984-08-16
    • Paul A. Bottomley
    • Paul A. Bottomley
    • G01R33/48A61B5/055A61B10/00G01N27/30G01R33/32G01R33/341G01R33/36G01R33/483G01R33/20
    • G01R33/3635G01R33/34007G01R33/341G01R33/3415G01R33/422G01R33/4831Y10S505/844
    • An NMR spectroscopy body probe is comprised of at least one surface coil, each coil having at least one turn and positioned adjacent to a first surface of an insulative member; an electric-field-reducing shield is fabricated upon the other surface of the relatively flexible substrate. The shield surface of the probe is to be positioned closest to the sample. A plurality of surface coil-bearing substrates can be stacked, one adjacent to the other with the planes thereof substantially parallel to each other and to the plane of the electric-field shield, and with each individual surface coil being separately tunable to a different nuclei species resonance frequency. Each surface coil can be utilized for both transmission and reception, or can be used for only reception of the re-radiated signal from the sample, with a separate excitation coil being provided with a radius substantially greater than the average radius of the (receiver) surface coil and positioned in the plane of any of the at least one receiving surface coils.
    • NMR光谱体探针由至少一个表面线圈组成,每个线圈具有至少一个匝并且邻近绝缘构件的第一表面定位; 在相对柔性的衬底的另一个表面上制造电场减小屏蔽。 探针的屏蔽表面应位于最靠近样品的位置。 多个表面线圈承载基板可以堆叠在一起,彼此相邻,其平面基本上彼此平行并且与电场屏蔽的平面相互间隔,并且每个单独的表面线圈可单独调节到不同的核 物种共振频率。 每个表面线圈可以用于发送和接收,或者可以仅用于接收来自样本的再辐射信号,其中单独的励磁线圈设置有大致大于(接收器)的平均半径的半径, 表面线圈并定位在所述至少一个接收表面线圈中的任何一个的平面中。
    • 96. 发明授权
    • Method of imaging by depth-resolved surface coil spectroscopy
    • 通过深度分辨表面线圈光谱法进行成像的方法
    • US4629988A
    • 1986-12-16
    • US626941
    • 1984-07-02
    • Paul A. Bottomley
    • Paul A. Bottomley
    • A61B10/00A61B5/055G01N24/08G01R33/48G01R33/483G01R33/20
    • G01R33/4831
    • A method for obtaining spatially resolved nuclear magnetic resonance chemical shift spectra, by depth-resolved surface coil spectroscopy (DRESS), substantially eliminates surface tissue contamination of the chemical shift spectra by employing selective excitation in the presence of a gradient magnetic field directed coaxial with the axis of a surface coil. The nuclei in a disk-shaped preselected volume are excited by a selective radio-frequency signal pulse applied in the presence of the gradient field. The surface coil is always utilized for receiving magnetic resonance response signals, while the same surface coil, or a separate transmitting antenna, can be used to provide the radio-frequency excitation field across the selected disk-shaped volume. The technique can be combined with conventional 90.degree.-.tau.-180.degree. or 180.degree.-.tau.-90.degree. relaxation time measurement RF pulse sequences, or with a solvent suppression NMR spectroscopy technique employing selective excitation.
    • 通过深度分辨表面线圈光谱(DRESS)获得空间分辨的核磁共振化学位移光谱的方法基本上消除了化学位移谱的表面组织污染,通过在与 表面线圈的轴线。 盘状预选容积中的细胞核通过在梯度场的存在下施加的选择性射频信号脉冲激发。 表面线圈总是用于接收磁共振响应信号,而相同的表面线圈或单独的发射天线可用于在所选择的盘形体上提供射频激励场。 该技术可以与常规的90°-180°或180°-TU-90°弛豫时间测量RF脉冲序列或采用选择性激发的溶剂抑制NMR光谱技术结合。
    • 99. 发明公开
    • RF BASED SPATIALLY SELECTIVE EXCITATION IN MRI
    • AUF HF BASIERENDERÄUMLICHSELEKTIVE ERREGUNG BEI MRI
    • EP2147329A4
    • 2012-03-21
    • EP08757081
    • 2008-05-02
    • CA NAT RESEARCH COUNCIL
    • SHARP JONATHANKING SCOTT
    • G01R33/54G01R33/3415G01R33/483
    • G01R33/4831G01R33/34076G01R33/3415G01R33/3607G01R33/4833
    • Herein a method for slice selection is provided in an MRI process, the method involves controlling a transmit array by adding low flip angle RF pulses interspersed between refocusing pulses that are used to move a k-space weighting function with respect to one or more B 1 fields used to deposit energy according to a desired k-space weighting function. The low flip angle pulses deposit energy so that an envelope traced by the low flip angle pulses in the k-space weighting function is related to a desired spatially excited region of the sample volume, for example by a Fourier transform, if the phase encoding directions are linear axes that coordinatize the sample volume, and the B 1 fields have linear phase gradients.
    • 这里,在MRI处理中提供了切片选择的方法,该方法包括通过将用于相对于一个或多个B 1移动k空间加权函数的重聚焦脉冲之间的散布的低翻转角RF脉冲相加来控制发射阵列 用于根据期望的k空间加权函数来存储能量的场。 低翻转角脉冲沉积能量,使得通过k空间加权函数中的低翻转角脉冲跟踪的包络与样本体积的期望的空间激发区域有关,例如通过傅立叶变换,如果相位编码方向 是使样本体积协调的线性轴,B 1场具有线性相位梯度。