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    • 96. 发明公开
    • 약효가 증강된 현호색 추출물, 그 제조방법 및 그를함유하는 조성물
    • 具有加强药物活性的柯氏硬脂酸酯的提取物及其制备方法及其组合物
    • KR1020100007520A
    • 2010-01-22
    • KR1020080068176
    • 2008-07-14
    • 대구한의대학교산학협력단
    • 이종록김상찬박숙자조미정박상미
    • A61K36/505
    • Y02A50/473A61K36/505A61K2236/33A61K2236/51Y10S514/859Y10S514/8995
    • PURPOSE: An antibacterial composition containing Corydalis turtschaninovii extract having enhanced drug effect is provided to increase dehydrocorydaline content. CONSTITUTION: A method for producing Corydalis turtschaninovii extract with enhanced drug effect comprises: a first step of adding 10-50% of acid solution(w/w%) and dipping for 1 to 30 hours; a second step of dipping Corydalis turtschaninovii at 150-400°C and heating for 0 to 2 hours; and a third step of extracting with water, low alcohol, or mixture solvent at 0°C-100°C for 30 to 90 hours through hot water extract, cooling extract, or ultrasonic wave and concentrating. A composition having antibacterial activity contains Corydalis turtschaninovii extract as an active ingredient. A pharmaceutical composition for preventing and treating dental caries and acne contains 0.1-100 weight% of Corydalis turtschaninovii extract.
    • 目的:提供含有提高药效的延胡索提取物的抗菌组合物,以提高脱氢含量。 构成:提高药效的延胡索提取物的方法包括:加入10-50%酸溶液(w / w%)和浸渍1〜30小时的第一步; 将紫草(Corydalis turtschaninovii)浸在150-400℃并加热0至2小时的第二步; 第3步骤,通过热水提取物,冷却提取物或超声波在0℃〜100℃下用水,低醇或混合溶剂萃取30〜90小时,并进行浓缩。 具有抗菌活性的组合物含有紫草提取物作为活性成分。 用于预防和治疗龋齿和痤疮的药物组合物含有0.1-100重量%的延胡索(Corydalis turtschaninovii)提取物。
    • 98. 发明公开
    • 항-빈맥성 부정맥을 위한 조제용 물질 및 이의 제조방법
    • 用于抗沙眼药的制剂及其制备方法
    • KR1020140000658A
    • 2014-01-03
    • KR1020130073136
    • 2013-06-25
    • 화신규안 오브 차이니즈 메디신 리서치 앤드 디벨롭먼트 컴퍼니 리미티드 인 순더 디스트릭트 오브 포산
    • 첸,케지두,슈잉마,샤오창
    • A61K36/505A61K9/20A61K9/16A61P9/06
    • A61K36/66A61K36/505A61K2236/39
    • The present invention relates to a corydaline extract for anti-tachyarrhythmia, wherein the extract is prepared by the following steps of: extracting 100 parts by weight of unprocessed corydaline powder in 600 to 1,000 parts by volume of 60-80% ethanol once to three times; filtering and mixing the extract; concentrating the mixture under the reduced pressure using a fluidextract having a relative density of 0.2 to 0.5 g/mL; adding a processed 101 resin, making the fluidextract to have a flow rate of 0.2 to 0.5 mL/min, and removing impurities by using deionized water having a flow rate of 0.2 to 0.5 mL/min; eluting 60 to 90% of ethanol by using the fluidextract having a flow rate of 0.4 to 0.8 mL/min; and concentrating the eluate to prepare a corydaline-extracted dry paste. The corydaline extract is formulated into clinically acceptable pills, capsules, granules, tablets, oral liquid, or injection, in a general manner in which conventional accessories are added. The extract exhibits a remarkable effect in the treatment of anti-tachyarrhythmia. [Reference numerals] (AA) Maximal adsorption capacity; (BB) Amount of desorption
    • 本发明涉及一种抗慢性心律失常的紫草提取物,其中提取物通过以下步骤制备:将600重量份未加工的桃红色粉末以600至1,000体积份的60-80%乙醇提取1次至3次 ; 过滤和混合提取物; 使用相对密度为0.2〜0.5g / mL的流质萃取物在减压下浓缩混合物; 加入加工的101树脂,使流质提取液的流速为0.2〜0.5 mL / min,并通过使用流量为0.2〜0.5 mL / min的去离子水除去杂质; 通过使用流速为0.4〜0.8mL / min的流质提取物洗脱60〜90%的乙醇; 并浓缩洗脱液以制备提花干燥的糊状物。 紫草提取物以通常添加常规附件的方式配制成临床可接受的丸剂,胶囊,颗粒剂,片剂,口服液体或注射剂。 该提取物在治疗抗快速性心律失常方面表现出显着的效果。 (AA)最大吸附容量; (BB)解吸量