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    • 4. 发明公开
    • 감초, 소맥 및 대조의 혼합 생약 추출물을 유효성분으로 함유하는 뇌신경 보호 효과를 나타내는 식품첨가제
    • 转基因食品添加剂组合物显示胚胎神经细胞的保护活性
    • KR1020070095485A
    • 2007-10-01
    • KR1020050085355
    • 2005-09-13
    • 대구한의대학교산학협력단
    • 김상찬변성희이종록양재하서정철박숙자
    • A23L1/29A23L1/22A23P1/04
    • A23L33/105A23L27/00A23L33/40
    • A food additive composition containing a mixed herb medicine extract of licorice root, wheat, and jujube is provided to be used as a food additive by confirming an excellent cerebral nerve protecting activity which shows the shortening of escape latency through the water-maze performance in animal models having cerebral nerve damage derived by beta amyloid. A food additive composition containing a mixed herb medicine extract of licorice root, wheat, and jujube is prepared by mixing licorice root, wheat, and jujube in a dried weight ratio of 1~10:5~50:1~10; settling the herb mixture in distilled water as a solvent at 30~100°C for 0.5~10hr, wherein the volume ratio of the herb mixture and the distilled water is 1:1~30; hydrothermal-extracting it; centrifuging, filtering, and concentrating the extract, wherein the 0.01~90wt% of the extract is included in 100wt% of the composition. In addition, other herb medicine is able to be selected from the group consisting of Euphoria longana, Bambusae Caulis in Liquamen, Astragali radix, Zizyphi spinosi Semen, Amomum villosum Lour, radish, ginseng, pine needles, red ginseng, Alpinia oxyphylla miquel, Polygala tenuifolia Willdenow, or iris. The extracting solvent is one or more solvents selected from the group consisting of water comprising refined water, C1-C4 lower alcohol, or propylene glycol, ethyl acetate, butylene glycol, ether, and chloroform.
    • 提供含有甘草根,小麦和枣混合草本药物提取物的食品添加剂组合物,用于通过确认优异的脑神经保护活性用作食品添加剂,其通过动物的水迷宫表现显示出逃避潜伏期的缩短 具有由β淀粉样蛋白衍生的脑神经损伤的模型。 通过将甘草根,小麦和枣以1〜10:5〜50:1〜10的干重比混合,制备含有甘草根,小麦和枣混合草药提取物的食品添加剂组合物; 将草药混合物在蒸馏水中作为溶剂在30〜100℃下沉降0.5〜10小时,其中草药混合物与蒸馏水的体积比为1:1〜30; 水热提取; 离心,过滤和浓缩提取物,其中提取物的0.01〜90重量%包括在组合物的100重量%中。 另外,其他草药能够选自丽花蕙兰,百草枯黄芪,黄芪,西葫芦精液,山茱萸,萝卜,人参,松针,红参,杏仁仁,Polygala tenuifolia Willdenow或虹膜。 萃取溶剂是选自由精制水,C1-C4低级醇或丙二醇,乙酸乙酯,丁二醇,乙醚和氯仿组成的组中的一种或多种溶剂。
    • 7. 发明公开
    • 소목 추출물을 유효성분으로 함유하는 여드름의 개선 및치료용 조성물
    • 一种组合物,其中包括用于改善和处理ACNE的茜草皂甙提取物
    • KR1020090055261A
    • 2009-06-02
    • KR1020070122095
    • 2007-11-28
    • 대구한의대학교산학협력단
    • 김상찬박숙자이종록양재하조미정최송이조용걸
    • A61K36/48A61P17/10A61K8/97
    • A composition for improving and treating acne vulgaris is provided to have antibacterial effect against P. acnes using a Caesalpinia sappan L. extract. A composition of skin external preperation for improving and treating acne vulgaris comprises 0.1-50 weight% of Caesalpinia sappan L. extract as an active ingredient. The extract is isolated using water, ethanol, methanol, propanol, butanol, acetone, ethylacetate, hexane, butylenes glycol, propylene glycol, hydrous butylenes glycol, hydrous propylene glycol and hydrous glycerin. The composition is used in a form of cream, gel, patch, ointment, plaster, lotion, liniment, or cataplasma agent. The composition is also used in a form of skin, lotion, nutrition lotion, nutrition cream, massage cream, essence, or pack.
    • 提供用于改善和治疗寻常痤疮的组合物,以使用Caesalpinia sappan L.提取物对痤疮丙酸杆菌具有抗菌作用。 用于改善和治疗寻常痤疮的皮肤外用组合物包含0.1-50重量%的Caesalpinia sappan L.提取物作为活性成分。 使用水,乙醇,甲醇,丙醇,丁醇,丙酮,乙酸乙酯,己烷,丁二醇,丙二醇,水合丁二醇,含水丙二醇和含水甘油分离提取物。 该组合物以乳膏,凝胶,贴剂,软膏,石膏,洗剂,搽剂或粘膜剂的形式使用。 该组合物还以皮肤,洗剂,营养洗剂,营养霜,按摩膏,精华液或包装的形式使用。