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91. 发明授权

US07299086B2 Wireless ECG in implantable devices 有权
标题翻译：无线心电图在植入式设备
公开(公告)号：US07299086B2
公开(公告)日：2007-11-20
申请号：US10795126
申请日：2004-03-05
申请人： Aaron McCabe , Avram Scheiner , Geng Zhang , Quan Ni , Douglas R. Daum , Yi Zhang
发明人： Aaron McCabe , Avram Scheiner , Geng Zhang , Quan Ni , Douglas R. Daum , Yi Zhang
IPC分类号： A61B5/0428 , A61N1/368
CPC分类号： A61B5/0402 , A61N1/365 , A61N1/3756
摘要： An implantable medical device such as an implantable pacemaker or implantable cardioverter/defibrillator includes a programmable sensing circuit providing for sensing of a signal approximating a surface electrocardiogram (ECG) through implanted electrodes. With various electrode configurations, signals approximating various standard surface ECG signals are acquired without the need for attaching electrodes with cables onto the skin. The various electrode configurations include, but are not limited to, various combinations of intracardiac pacing electrodes, portions of the implantable medical device contacting tissue, and electrodes incorporated onto the surface of the implantable medical device.
摘要翻译：诸如可植入起搏器或植入式心律转复/除颤器的可植入医疗装置包括可编程感测电路，用于通过植入电极感测接近表面心电图（ECG）的信号。通过各种电极配置，获取近似各种标准表面ECG信号的信号，而不需要将电极与电缆连接在皮肤上。各种电极配置包括但不限于心脏内起搏电极，可植入医疗器械接触组织的部分和结合到可植入医疗装置的表面上的电极的各种组合。

92. 发明授权

US07286990B1 Universal interface for voice activated access to multiple information providers 有权
标题翻译：用于语音激活访问多个信息提供者的通用接口
公开(公告)号：US07286990B1
公开(公告)日：2007-10-23
申请号：US09889911
申请日：2000-01-21
申请人： Paul Edmonds , Yi Zhang , George Sollman , Michael P. Tel , Chang Xu , Priyen Doshi , Stephen Co , David Weinstein , Andy Chan
发明人： Paul Edmonds , Yi Zhang , George Sollman , Michael P. Tel , Chang Xu , Priyen Doshi , Stephen Co , David Weinstein , Andy Chan
IPC分类号： G10L21/06
CPC分类号： H04M3/4938 , H04M2203/2072 , H04M2203/4509
摘要： An interface for accessing data from one or more information systems using a wireless telephone or other user device. The interface is presented to a user as an abstraction of a unified mailbox and permits access by the user to messaging and other services from the wireless device. The interface is coupled to one or more converting modules to convert user inputs from the format in which they are received into a format that may be input to the desired information system.
摘要翻译：用于使用无线电话或其他用户设备从一个或多个信息系统访问数据的接口。该接口作为统一邮箱的抽象呈现给用户，并允许用户从无线设备访问消息传递和其他服务。接口耦合到一个或多个转换模块，以将用户输入从其接收的格式转换成可输入到期望的信息系统的格式。

93. 发明申请

US20070076936A1 Fast alignment of large-scale sequences using linear space techniques 审中-公开
标题翻译：使用线性空间技术快速对齐大规模序列
公开(公告)号：US20070076936A1
公开(公告)日：2007-04-05
申请号：US11240763
申请日：2005-09-30
申请人： Eric Li , Tao Wang , Yi Zhang
发明人： Eric Li , Tao Wang , Yi Zhang
IPC分类号： G06K9/00 , G06K9/62 , G06F19/00
CPC分类号： G16B30/00 , G06K9/6206
摘要： Large scale sequences and other types of patterns may be matched or aligned quickly using a linear space technique. In one embodiment, the invention includes, calculating a similarity matrix of a first sequence against a second sequence, determining a lowest cost path through the matrix, where cost is a function of sequence alignment, dividing the similarity matrix into a plurality of blocks, determining local start points on the lowest cost path, the local start points each corresponding to a block through which the lowest cost path passes, dividing sequence alignment computation for the lowest cost path into a plurality of independent problems based on the local start points, solving each independent problem independently, and concatenating the solutions to generate an alignment path of the first sequence against the second sequence.
摘要翻译：使用线性空间技术可以快速匹配或对齐大规模序列和其他类型的图案。在一个实施例中，本发明包括：计算第一序列与第二序列的相似度矩阵，确定通过矩阵的最低成本路径，其中成本是序列比对的函数，将相似性矩阵划分为多个块，确定最低成本路径上的本地起始点，每个对应于最低成本路径通过的块的本地起始点，基于本地起始点将最低成本路径的序列比对计算分解为多个独立问题，解决每个独立的问题，并且连接解决方案以产生第一序列与第二序列的对准路径。

94. 发明申请

US20070073181A1 Respiration monitoring using respiration rate variability 有权
标题翻译：呼吸监测使用呼吸频率变化
公开(公告)号：US20070073181A1
公开(公告)日：2007-03-29
申请号：US11514423
申请日：2006-09-01
申请人： Yachuan Pu , Yi Zhang , Gerrard Carlson
发明人： Yachuan Pu , Yi Zhang , Gerrard Carlson
IPC分类号： A61B5/08
CPC分类号： A61B5/0816
摘要： Systems and methods provide for detecting respiration disturbances and changes in respiration disturbances, preferably by detecting variability in one or more respiration parameters. Respiration rate variability is determined for a variety of diagnostic and therapeutic purposes, including disease/disorder detection, diagnosis, treatment, and therapy titration. Systems and methods provide for generating a footprint, such as a two- or three-dimensional histogram, representative of a patient's respiration parameter variability, and generating one or more indices representative of quantitative measurements of the footprint.
摘要翻译：系统和方法优选地通过检测一个或多个呼吸参数中的可变性来检测呼吸紊乱和呼吸干扰的变化。确定各种诊断和治疗目的的呼吸率变异性，包括疾病/病症检测，诊断，治疗和治疗滴定。系统和方法提供用于生成代表患者呼吸参数变异性的足迹（例如二维或三维直方图），以及生成代表足迹的定量测量的一个或多个指数。

95. 发明申请

US20070073169A1 System and method for generating a trend parameter based on respiration rate distribution 有权
标题翻译：基于呼吸速率分布生成趋势参数的系统和方法
公开(公告)号：US20070073169A1
公开(公告)日：2007-03-29
申请号：US11438977
申请日：2006-05-23
申请人： Viktoria Averina , Yi Zhang , Yousufali Dalal
发明人： Viktoria Averina , Yi Zhang , Yousufali Dalal
IPC分类号： A61B5/02 , A61B5/08
CPC分类号： A61B5/0816 , A61B5/053 , A61B5/411 , A61B2562/0219 , A61N1/3627 , A61N1/36521
摘要： Systems and methods provide for assessing the heart failure status of a patient and, more particularly, to generating a trend parameter based on a distribution of the patient's respiration rate. Systems and methods provide for detecting, using an implantable device or a patient-external device, patient respiration and computing a respiration rate based on the detected patient respiration. A distribution of the respiration rate is calculated, and a trend parameter based on the respiration rate distribution is generated. The trend parameter is indicative of a patient's heart failure status. An output signal indicative of the patient's heart failure status may be generated based on the trend parameter.
摘要翻译：系统和方法提供用于评估患者的心力衰竭状态，更具体地，用于基于患者的呼吸速率的分布来生成趋势参数。系统和方法提供用于基于检测到的患者呼吸来检测，使用可植入装置或患者外部装置进行患者呼吸并计算呼吸速率。计算呼吸率的分布，并生成基于呼吸率分布的趋势参数。趋势参数表示患者的心力衰竭状态。可以基于趋势参数生成表示患者心力衰竭状态的输出信号。

96. 发明申请

US20060282000A1 Ischemia detection using a heart sound sensor 有权
标题翻译：使用心脏声音传感器进行缺血检测
公开(公告)号：US20060282000A1
公开(公告)日：2006-12-14
申请号：US11148107
申请日：2005-06-08
申请人： Yi Zhang , Richard Fogoros , Carlos Haro , Yousufali Dalal , Marina Brockway , Krzysztof Siejko
发明人： Yi Zhang , Richard Fogoros , Carlos Haro , Yousufali Dalal , Marina Brockway , Krzysztof Siejko
IPC分类号： A61B5/02
CPC分类号： A61N1/3627 , A61B5/0031 , A61B5/024 , A61B5/0452 , A61B5/0456 , A61B7/04 , A61N1/36578 , A61N1/395
摘要： A system comprising an implantable medical device (IMD) includes an implantable heart sound sensor to produce an electrical signal representative of at least one heart sound. The heart sound is associated with mechanical activity of a patient's heart. Additionally, the IMD includes a heart sound sensor interface circuit coupled to the heart sound sensor to produce a heart sound signal, and a signal analyzer circuit coupled to the heart sound sensor interface circuit. The signal analyzer circuit measures a baseline heart sound signal, and deems that an ischemic event has occurred using, among other things, a measured subsequent change in the heart sound signal from the established baseline heart sound signal.
摘要翻译：包括可植入医疗装置（IMD）的系统包括可植入心音传感器，以产生代表至少一个心音的电信号。心脏声音与患者心脏的机械活动有关。另外，IMD包括耦合到心脏声音传感器以产生心脏声音信号的心脏声音传感器接口电路，以及耦合到心脏声音传感器接口电路的信号分析器电路。信号分析器电路测量基线心音信号，并且认为已经发生了缺血事件，其中使用来自已建立的基线心音信号的心音信号的测量后续变化。

97. 发明申请

US20060253162A1 Closed loop cardiac resynchronization therapy using cardiac activation sequence information 有权
标题翻译：闭环心脏再同步治疗使用心脏激活序列信息
公开(公告)号：US20060253162A1
公开(公告)日：2006-11-09
申请号：US11125068
申请日：2005-05-09
申请人： Yi Zhang , Yinghong Yu , Aaron McCabe , Jiang Ding , Jeffrey Stahmann , Carlos Ricci , Scott Meyer
发明人： Yi Zhang , Yinghong Yu , Aaron McCabe , Jiang Ding , Jeffrey Stahmann , Carlos Ricci , Scott Meyer
IPC分类号： A61N1/365
CPC分类号： A61N1/3712 , A61N1/3627 , A61N1/365 , G06F19/00
摘要： Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed to detect, monitor, track and/or trend closed-loop cardiac resynchronization therapy using cardiac activation sequence information. Devices and methods involve sensing a plurality of composite cardiac signals using a plurality of electrodes, the electrodes configured for implantation in a patient. A source separation is performed using the sensed plurality of composite cardiac signals, producing one or more cardiac signal vectors associated with all or a portion of one or more cardiac activation sequences. A cardiac resynchronization therapy is adjusted using one or both of the one or more cardiac signal vectors and the signals associated with the one or more cardiac signal vectors. In further embodiments, the cardiac resynchronization therapy may be initiated, terminated, or one or more parameters of the resynchronization therapy may be altered.
摘要翻译：提供一种或多种监测，诊断，除颤和起搏的心脏监测和/或刺激方法和系统。心脏信号分离用于使用心脏激活序列信息来检测，监测，跟踪和/或趋势闭环心脏再同步治疗。设备和方法包括使用多个电极感测多个复合心脏信号，所述电极被配置用于植入患者体内。使用所感测的多个复合心脏信号进行源分离，产生与一个或多个心脏激活序列的全部或一部分相关联的一个或多个心脏信号载体。使用一个或多个心脏信号向量和与一个或多个心脏信号载体相关联的信号中的一个或两个来调整心脏再同步治疗。在另外的实施方案中，心脏再同步治疗可以被启动，终止，或者可以改变再同步治疗的一个或多个参数。

98. 发明申请

US20060253044A1 Arrhythmia discrimination using electrocardiograms sensed from multiple implanted electrodes 有权
标题翻译：使用从多个植入电极感测的心电图的心律失常辨别
公开(公告)号：US20060253044A1
公开(公告)日：2006-11-09
申请号：US11125020
申请日：2005-05-09
申请人： Yi Zhang , Carlos Ricci , Jeffrey Stahmann , Aaron McCabe , Scott Meyer , Yinghong Yu
发明人： Yi Zhang , Carlos Ricci , Jeffrey Stahmann , Aaron McCabe , Scott Meyer , Yinghong Yu
IPC分类号： A61B5/04
CPC分类号： A61B5/04011 , A61B5/7203
摘要： Cardiac monitoring and/or stimulation methods and systems provide for monitoring, diagnosing, defibrillation and pacing therapies, or a combination of these capabilities, including cardiac systems incorporating or cooperating with neuro-stimulating devices, drug pumps, or other therapies. Embodiments of the present invention relate generally to implantable medical devices employing automated cardiac activation sequence monitoring and/or tracking for arrhythmia discrimination. Embodiments of the invention are directed to devices and methods involving sensing a plurality of composite cardiac signals using a plurality of implantable electrodes. A source separation is performed using the sensed plurality of composite cardiac signals and the separation produces one or more cardiac signal vectors associated with one or more cardiac activation sequences that is indicative of ischemia. A change of the one or more cardiac signal vectors is detected using the one or more cardiac signal vectors. Cardiac arrhythmias are discriminated using the one or more cardiac signal vectors.
摘要翻译：心脏监测和/或刺激方法和系统提供监测，诊断，除颤和起搏治疗，或这些功能的组合，包括结合或与神经刺激装置，药物泵或其他疗法组合的心脏系统。本发明的实施方案一般涉及使用自动心脏激活序列监测和/或跟踪用于心律失常鉴别的可植入医疗装置。本发明的实施例涉及使用多个可植入电极感测多个复合心脏信号的装置和方法。使用感测的多个复合心脏信号进行源分离，并且分离产生与指示缺血的一个或多个心脏激活序列相关联的一个或多个心脏信号载体。使用一个或多个心脏信号矢量检测一个或多个心脏信号矢量的改变。使用一个或多个心脏信号载体来区分心律失常。

99. 发明申请

US20060253043A1 Posture monitoring using cardiac activation sequences 有权
标题翻译：使用心脏激活序列的姿势监测
公开(公告)号：US20060253043A1
公开(公告)日：2006-11-09
申请号：US11124950
申请日：2005-05-09
申请人： Yi Zhang , Robert Sweeney
发明人： Yi Zhang , Robert Sweeney
IPC分类号： A61B5/04
CPC分类号： A61B5/0472 , A61B5/1116 , A61B5/686 , A61B5/7203 , A61B2560/0219 , A61B2560/0468 , A61B2562/046 , A61N1/3627 , A61N1/365 , A61N1/3712
摘要： Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed to detect, monitor, track and/or trend a patient's posture using cardiac activation sequence information. Devices and methods in accordance with the present invention involve sensing a plurality of composite cardiac signals using a plurality of implantable electrodes. A source separation is performed using the composite cardiac signals, which produces one or more cardiac signal vectors associated with all or a portion of one or more cardiac activation sequences. A change in a patient's posture is detected using the cardiac signal vectors. Further embodiments involve sensing the plurality of composite cardiac signals during the patient's predominant cardiac rhythm before detecting the change in the patient's posture. Other embodiments involve discriminating between one of a postural related change and a cardiac rhythm related change using the cardiac signal vectors.
摘要翻译：提供一种或多种监测，诊断，除颤和起搏的心脏监测和/或刺激方法和系统。使用心脏信号分离来使用心脏激活序列信息来检测，监测，跟踪和/或趋向于患者的姿势。根据本发明的装置和方法涉及使用多个可植入电极感测多个复合心脏信号。使用复合心脏信号进行源分离，其产生与一个或多个心脏激活序列的全部或一部分相关联的一个或多个心脏信号载体。使用心脏信号矢量检测患者姿势的变化。另外的实施例涉及在检测患者姿势的变化之前在患者的主要心律期间感测多个复合心脏信号。其他实施例涉及使用心脏信号矢量区分姿势相关变化和心律相关变化中的一个。

100. 发明申请

US20060221890A1 Method and apparatus for implementing voice group call service and data group call service by circuit switch or packet switch respectively in mobile network 审中-公开
标题翻译：分别在移动网络中通过电路交换机或分组交换机实现语音组呼叫业务和数据组呼叫业务的方法和装置
公开(公告)号：US20060221890A1
公开(公告)日：2006-10-05
申请号：US11372138
申请日：2006-03-10
申请人： Enyuan Qian , Songhai Wang , Jun Song , Yi Zhang , Xiaofeng Qin
发明人： Enyuan Qian , Songhai Wang , Jun Song , Yi Zhang , Xiaofeng Qin
IPC分类号： H04Q7/00 , H04L12/66
CPC分类号： H04L65/4061 , H04L65/1016 , H04L65/1069 , H04L65/403 , H04W4/06 , H04W72/005 , H04W76/40 , H04W88/06
摘要： The present invention provides a method and corresponding apparatus for multimedia group call service in mobile network. According to the present invention, voice group call is established by circuit switch while data group call is established by packet switch. Compared with the prior art, the solutions disclosed in the present invention can shorten the “Call Setup latency” and “Intra-call latency” when performing voice group call and can provide better link quality.
摘要翻译：本发明提供一种用于移动网络中的多媒体组呼叫服务的方法和相应装置。根据本发明，在通过分组交换建立数据组呼叫的同时，通过电路交换机建立语音组呼叫。与现有技术相比，本发明公开的解决方案可以在执行语音组呼叫时缩短“呼叫建立延迟”和“呼叫延迟时间”，并且可以提供更好的链路质量。

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