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91. 发明授权

US08057119B2 Cosmetic applying device 有权
标题翻译：化妆品施用装置
公开(公告)号：US08057119B2
公开(公告)日：2011-11-15
申请号：US12432041
申请日：2009-04-29
申请人： Jun Zhang
发明人： Jun Zhang
IPC分类号： A46B11/04
CPC分类号： B65D47/242 , A45D34/04 , A46B11/0013 , A46B11/0041 , A46B11/0086 , A46B2200/1046 , B65D47/248
摘要： A cosmetic applying device includes a soft tube with an end member connected to the open end of the soft tube in which fluid cosmetic material is received. The end member has two through holes in the closed end and an engaging portion extending from an inner end of the closed end. A core piece has an end inserted into the end member and an applying head extends through a passage in the core piece. A cap is threadedly connected to the soft tube to protect the applying head. When the cap is connected to the soft tube, the passage of the core piece is sealed by the engaging portion to prevent air and cosmetic material from entering the soft tube. When the cap is removed from the soft tube, the core piece is moved and the engaging portion is disengaged from the passage.
摘要翻译：化妆品涂抹装置包括软管，其端部件连接到软管的开口端，其中容纳流体化妆品材料。端部构件在封闭端部具有两个通孔和从封闭端的内端延伸的接合部分。芯片具有插入端部构件中的端部，并且施加头部延伸穿过芯部件中的通道。盖帽螺纹连接到软管上以保护施加头。当盖连接到软管时，芯片的通道被接合部分密封，以防止空气和化妆品进入软管。当帽从软管中取出时，芯片移动并且接合部分从通道脱离。

92. 发明申请

US20110246870A1 VALIDATING MARKUP LANGUAGE SCHEMAS AND SEMANTIC CONSTRAINTS 审中-公开
标题翻译：验证标记语言规划和语义约束
公开(公告)号：US20110246870A1
公开(公告)日：2011-10-06
申请号：US12753189
申请日：2010-04-02
申请人： Shiguang Dong , Haiyang Gao , Jun Zhang , Dong-Hui Zhang
发明人： Shiguang Dong , Haiyang Gao , Jun Zhang , Dong-Hui Zhang
IPC分类号： G06F17/00 , G06F11/07
CPC分类号： G06F11/3604
摘要： Semantic constraints and schemas may be validated in markup language documents. A computer may be utilized to receive a strongly-typed document object model representing a markup language document. The computer may then be utilized to load semantic constraints and validate the strongly-typed document object model representing the markup language document to determine whether the semantic constraints have been met. Then, the computer may be utilized to generate a result based on the validation. The computer may also be utilized to load schema constraints for a schema used to define a markup language document and validate a strongly-typed document object model representing the markup language document against the schema constraints. Then, the computer may be utilized to generate a result based on the validation.
摘要翻译：语义约束和模式可以在标记语言文档中进行验证。可以使用计算机来接收表示标记语言文档的强类型的文档对象模型。然后可以利用计算机来加载语义约束并验证表示标记语言文档的强类型的文档对象模型，以确定语义约束是否已被满足。然后，计算机可以用于基于验证产生结果。计算机还可以用于加载用于定义标记语言文档的模式的模式约束，并根据模式约束验证表示标记语言文档的强类型文档对象模型。然后，计算机可以用于基于验证产生结果。

93. 发明申请

US20110243904A1 RNA INTERFERENCE TARGET FOR TREATING AIDS 审中-公开
标题翻译：用于治疗艾滋病的RNA干扰目标
公开(公告)号：US20110243904A1
公开(公告)日：2011-10-06
申请号：US12602005
申请日：2008-06-02
申请人： Tong Cheng , Tao Zhang , Yali Zhang , Ji Miao , Jun Zhang , Ningshao Xia
发明人： Tong Cheng , Tao Zhang , Yali Zhang , Ji Miao , Jun Zhang , Ningshao Xia
IPC分类号： A61K48/00 , C07H21/04 , C12N15/63 , C07H21/02 , C12N15/85 , C12N5/10 , C12N1/00 , A61K31/713 , A61K31/7088 , A61K35/12 , A61P31/18
CPC分类号： C12N15/1132 , C12N2310/11 , C12N2310/12 , C12N2310/14
摘要： The present invention relates to RNA interference target sequence targeting HIV for the treatment of AIDS. Based on the target sequence, recombinant expression vectors, packaging vectors and cells were constructed, which express a siRNA and/or a miRNA and/or a ribozyme and/or an antisense oligonucleotide targeting HIV. Also provided is the use of the recombinant expression vectors, packaging vectors and recombinant cells in the manufacture of a medicament for the treatment of AIDS.
摘要翻译：本发明涉及靶向用于治疗AIDS的HIV的RNA干扰靶序列。基于靶序列，构建重组表达载体，包装载体和细胞，其表达siRNA和/或miRNA和/或靶向HIV的核酶和/或反义寡核苷酸。还提供了重组表达载体，包装载体和重组细胞在制备用于治疗AIDS的药物中的用途。

94. 发明申请

US20110238001A1 NANOPARTICLE BASED PHOTODYNAMIC THERAPY AND METHODS OF MAKING AND USING SAME 审中-公开
标题翻译：基于纳米光度的光化疗法及其制备方法
公开(公告)号：US20110238001A1
公开(公告)日：2011-09-29
申请号：US13151858
申请日：2011-06-02
申请人： Wei Chen , Jun Zhang
发明人： Wei Chen , Jun Zhang
IPC分类号： A61M37/00
CPC分类号： B82Y5/00 , A61K33/00 , A61K41/0052 , A61K41/0071 , A61K45/06 , A61K47/551 , A61K47/6911 , A61K47/6923 , A61K47/6929 , A61N5/062 , A61N2005/1098 , Y02A50/473
摘要： A novel method for cancer treatment that combines radiotherapy and photodynamic therapy (PDT). More particularly, luminescent nanoparticles with attached photosensitizers, such as porphyrins, are used as a new type of agent for photodynamic therapy. Upon exposure to ionizing radiation, light will emit from the nanoparticles to activate the photosensitizers; as a consequence, a singlet oxygen is produced to augment the killing of cancer cells by ionizing radiation. No external light is necessary to activate the photosensitizing agent within tumors. The combination of radiotherapy and PDT is more efficient than either used alone.
摘要翻译：一种结合放射治疗和光动力治疗（PDT）的新型癌症治疗方法。更具体地，使用具有附着的光敏剂如卟啉的发光纳米颗粒作为光动力学治疗的新型试剂。暴露于电离辐射后，光将从纳米颗粒中发射以激活光敏剂; 因此，产生单线态氧以增加通过电离辐射杀死癌细胞。不需要外部光来激活肿瘤内的光敏剂。放射治疗和PDT的组合比单独使用更有效。

95. 发明申请

US20110212081A1 KRÜPPEL-LIKE FACTORS AND FAT REGULATION 审中-公开
标题翻译： KRÜPPEL-LIKE因子和脂肪调节
公开(公告)号：US20110212081A1
公开(公告)日：2011-09-01
申请号：US13107202
申请日：2011-05-13
申请人： Sarwar Hashmi , Chuan Yang , Jun Zhang , Cheng-Han Huang
发明人： Sarwar Hashmi , Chuan Yang , Jun Zhang , Cheng-Han Huang
IPC分类号： A61K39/395 , C12N5/02 , C12N5/00 , A61K38/00 , A61K31/7088 , A61P3/00
CPC分类号： A61K38/1709 , C07K14/4702 , C12N15/113 , C12N2310/14
摘要： Disclosed herein are methods and cell lines used in fat regulation. The methods and cell lines incorporate Krüppel-like factors including, without limitation, klf-1 and klf-3.
摘要翻译：本文公开了用于脂肪调节的方法和细胞系。方法和细胞系包含Krüppel样因子，包括但不限于klf-1和klf-3。

96. 发明申请

US20110152205A1 APPLICATION OF PUERARIN IN THE PREPARATION OF P2X3 MEDIATED DRUGS FOR PAIN/NERVOUS SYSTEM DISEASES 失效
标题翻译：在制备P2X3介导的药物用于疼痛/神经系统疾病中应用PUERARIN
公开(公告)号：US20110152205A1
公开(公告)日：2011-06-23
申请号：US12922245
申请日：2010-06-29
申请人： Shangdong Liang , Changshui Xu , Yun Gao , Guilin Li , Jiari Lin , Shuangmei Liu , Han Liu , Jun Zhang , Xin Li
发明人： Shangdong Liang , Changshui Xu , Yun Gao , Guilin Li , Jiari Lin , Shuangmei Liu , Han Liu , Jun Zhang , Xin Li
IPC分类号： A61K31/7034 , A61P25/00 , A61P29/00
CPC分类号： A61K31/352
摘要： The invention relates to the new usage of puerarin in the field of pharmaceutical products, in other words, it relates to the application of puerarin in the preparation of drugs for P2X3 mediated pain/nervous system diseases. The experiment shows that puerarin can inhibit pain-related behavioral responses, subsequently immunohistochemical analysis, in situ hybridization, RT-PCR, protein blotting and other techniques were utilized to observe the inhibition of puerarin on mRNA and protein expression of P2X3 receptor in dorsal root ganglion of rats with neuropathic pain and in dorsal root ganglion and sensory nerve ending in the burn model of rats, it was found by using whole-cell patch clamp technique that puerarin can significantly reduce the electric current activated by P2X3 receptor agonist in the neuron of dorsal root ganglion of rats with neuropathic pain. The experiment proves that the mechanism for the inhibitory effects of puerarin on acute and chronic pain is to block the transmission of pain sense information that is mediated by P2X3 receptor in primary sensory neurons. The invention provides a kind of new method for the prevention and treatment on acute and chronic pain, and it also indicates that puerarin can act as a antagonist for P2X3 receptor, which will be helpful for the application of drugs in the prevention and treatment on P2X3 receptor involved nervous system diseases.
摘要翻译：本发明涉及葛根素在药物领域的新用途，换句话说，涉及葛根素在制备P2X3介导的疼痛/神经系统疾病药物中的应用。实验表明，葛根素可以抑制疼痛相关的行为反应，随后免疫组化分析，原位杂交，RT-PCR，蛋白质印迹等技术用于观察葛根素对背根神经节P2X3受体mRNA和蛋白表达的抑制作用的大鼠神经性疼痛和背根神经节和感觉神经结束于大鼠烧伤模型，通过使用全细胞膜片钳技术发现，葛根素可以显着降低P2X3受体激动剂在背侧神经元中活化的电流神经性疼痛大鼠根神经节。实验证明，葛根素对急性和慢性疼痛的抑制作用机制是阻断P2X3受体介导的疼痛感知信息在原发感觉神经元中的传播。本发明提供了一种预防和治疗急性和慢性疼痛的新方法，也表明葛根素可以作为P2X3受体的拮抗剂，有利于药物在P2X3的预防和治疗中的应用受体涉及神经系统疾病。

97. 发明授权

US07876191B2 Power converter employing a tapped inductor and integrated magnetics and method of operating the same 有权
标题翻译：采用抽头电感器和集成磁体的功率转换器及其操作方法
公开(公告)号：US07876191B2
公开(公告)日：2011-01-25
申请号：US11942632
申请日：2007-11-19
申请人： Sriram Chandrasekaran , Kris Y. Kao , Jun Zhang
发明人： Sriram Chandrasekaran , Kris Y. Kao , Jun Zhang
IPC分类号： H01F27/34
CPC分类号： H01F27/2847 , H01F3/14 , H02M3/158 , H02M2001/0064
摘要： A power converter employing a magnetic device including a magnetic core and first and second tapped windings. Each winding of the magnetic device has first and second winding sections, respectively, coupled to the magnetic core, wherein the first and second winding sections are formed from a formed and folded planar conductive sheet. The magnetic core includes a common leg, a plurality of outer legs, and a top plate. The first and second winding sections are constructed with a formed and folded planar conductive sheet formed with structures usable as pins in a through-hole, surface-mount, or combined printed wiring board assembly process. The outer legs at either end of the magnetic core are positioned back from magnetic core ends, and the magnetic core is formed with a stepped structure to accommodate winding pins in a surface-mount printed wiring board assembly process.
摘要翻译：一种使用包括磁芯和第一和第二抽头绕组的磁性装置的功率转换器。磁性装置的每个绕组分别具有耦合到磁芯的第一和第二绕组部分，其中第一和第二绕组部分由成形和折叠的平面导电片形成。磁芯包括公共腿，多个外腿和顶板。第一和第二绕组部分由在通孔，表面安装或组合的印刷线路板组装工艺中形成为可用作销的结构的成形和折叠的平面导电片构成。磁芯两端的外腿位于磁芯端部的后面，磁芯形成阶梯状结构，以便在表面贴装印刷电路板组装工艺中容纳卷绕销。

98. 发明申请

US20110009752A1 ENDOSCOPIC LONG RANGE FOURIER DOMAIN OPTICAL COHERENCE TOMOGRAPHY (LR-FD-OCT) 有权
标题翻译：内镜长距离光域相干光谱（LR-FD-OCT）
公开(公告)号：US20110009752A1
公开(公告)日：2011-01-13
申请号：US12833717
申请日：2010-07-09
申请人： Zhongping Chen , Jun Zhang , Matthew Brenner
发明人： Zhongping Chen , Jun Zhang , Matthew Brenner
IPC分类号： A61B1/267 , A61B6/00 , A61B1/07
CPC分类号： A61B5/0073 , A61B5/0066 , A61B5/6852 , A61B5/7257 , G01B9/02004 , G01B9/02007 , G01B9/02091 , G01B2290/45
摘要： An endoscopic swept-source Fourier Domain optical coherence tomographic system (FDOCT system) for imaging of tissue structure includes a Fourier Domain mode locked (FDML), high speed, narrow line-width, wavelength swept source, an OCT interferometer having a sample arm, a reference arm, a detection arm, and a source arm coupled to the swept source, an endoscopic probe coupled to the sample arm, and a data processing circuit coupled to the detection arm. The swept source includes a long optic fiber functioning as a cavity, a high optical gain lasing module, and a tunable narrow bandwidth bandpass filter for wavelength selection combined to form a unidirectional ring laser cavity, where the tunable narrow bandwidth bandpass filter is driven synchronously with the optical round-trip time of a propagating light wave in the cavity.
摘要翻译：用于组织结构成像的内窥镜扫描傅立叶域光学相干断层扫描系统（FDOCT系统）包括傅立叶域模式锁定（FDML），高速窄线宽波长扫描源，具有采样臂的OCT干涉仪，耦合到扫描源的参考臂，检测臂和源臂，耦合到采样臂的内窥镜探针以及耦合到检测臂的数据处理电路。扫频源包括用作空腔的长光纤，高光增益激光模块和用于波长选择的可调窄带宽带通滤波器，以组合形成单向环形激光腔，其中可调窄带宽带通滤波器与传播光波在空腔中的光学往返时间。

99. 发明申请

US20100296489A1 Method of Uplink Multi-Cell Joint Detection in a Time Division-Synchronous Code Division Multiple Access System 审中-公开
标题翻译：时分同步码分多址系统上行多小区联合检测方法
公开(公告)号：US20100296489A1
公开(公告)日：2010-11-25
申请号：US12808245
申请日：2007-12-18
申请人： Jun Zhang , Meiling Ding , He Huang
发明人： Jun Zhang , Meiling Ding , He Huang
IPC分类号： H04B7/216
CPC分类号： H04W24/10 , H04W24/00 , H04W48/08 , H04W76/10 , H04W88/08 , H04W88/12
摘要： The present invention discloses a method for uplink multi-cell joint detection in a Time Division-Synchronous Code Division Multiple Access system to realize uplink multi-cell joint detection by a Node B. The method comprises: a radio network controller sending neighbor cell channel updating information to neighbor Node Bs of a cell where a user terminal is located when a Node B application part protocol process happens at an Iub interface to establish a radio link for the user terminal; and the neighbor Node Bs adding information of the user terminal into an uplink multi-cell joint detection information of the cell where uplink joint detection is required to be performed for the user terminal after receiving the neighbor cell channel updating information. The method of the present invention realizes uplink multi-cell joint detection by a Node B.
摘要翻译：本发明公开了一种时分同步码分多址系统中的上行多小区联合检测方法，用于实现节点B的上行多小区联合检测。该方法包括：无线网络控制器发送相邻小区信道更新当在Iub接口发生节点B应用部分协议进程以建立用户终端的无线电链路时，向用户终端所在的小区的邻居节点B发送信息; 邻居节点B将用户终端的信息添加到在接收到相邻小区信道更新信息之后需要对用户终端执行上行链路联合检测的小区的上行链路多小区联合检测信息。本发明的方法实现了节点B的上行链路多小区联合检测。

100. 发明授权

US07813536B2 Image measuring apparatus and method, and image measuring system for glomerular filtration rate 有权
标题翻译：图像测量装置和方法，以及用于肾小球滤过率的图像测量系统
公开(公告)号：US07813536B2
公开(公告)日：2010-10-12
申请号：US11636475
申请日：2006-12-11
申请人： Hongfeng Ma , Qiang Di , Lei Wu , Honglei Fu , Longwei Mei , Liang Tian , Songmin Quan , Jun Zhang , Yan Kang
发明人： Hongfeng Ma , Qiang Di , Lei Wu , Honglei Fu , Longwei Mei , Liang Tian , Songmin Quan , Jun Zhang , Yan Kang
IPC分类号： G06K9/00
CPC分类号： G06K9/34 , A61B6/50 , G06K2209/05 , G06T7/0012 , G06T7/11 , G06T2207/10081 , G06T2207/30084
摘要： The present invention discloses an abdominal CT image measuring apparatus and method. The abdominal CT image measuring apparatus includes: an interface unit; a part recognizing unit and a characteristic data computing unit. The present invention can determine the specific region of the part under test with a little amount of computation, by registration and subtraction operation on the two-phase scan images. This is easy to be carried out in computers, thus the computing speed of the characteristic data can be guaranteed and the efficiency can be improved. By the recognizing of the kidney regions and the abdominal aorta region in the present invention, the glomerular filtration rates obtained by applying the key concept of the present invention to the image measuring of glomerular filtration rate can meet the clinical application requirements in both precision and speed.
摘要翻译：本发明公开了一种腹部CT图像测量装置及方法。腹部CT图像测量装置包括：接口单元; 部件识别单元和特征数据计算单元。本发明可以通过对两相扫描图像进行配准和减法操作，通过少量的计算来确定待测零件的特定区域。这在计算机中很容易实现，因此可以保证特征数据的计算速度并提高效率。通过本发明的肾脏区域和腹主动脉区域的识别，通过将本发明的关键概念应用于肾小球滤过率的图像测定而获得的肾小球滤过率可以满足临床应用的精度和速度要求。

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