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    • 96. 发明授权
    • Acrylic foam pressure sensitive adhesive method thereof
    • 丙烯酸泡沫压敏粘合剂方法
    • US06746725B2
    • 2004-06-08
    • US10344309
    • 2003-02-10
    • Shojitsu NakamutaHiroshi KikuchiShinji Abiko
    • Shojitsu NakamutaHiroshi KikuchiShinji Abiko
    • B05D300
    • C08J9/122C08J2207/02C08J2333/06C08L33/00C09J5/08C09J7/10C09J2433/00
    • An acrylic foam pressure sensitive adhesive, having a low density and having cells finely and uniformly dispersed therein, and its production method. An acrylic foam pressure sensitive adhesive having a cell average diameter of no more than 300 &mgr;m and its standard deviation of no more than 115 &mgr;m. A production method of an acrylic foam pressure sensitive adhesive comprising: introducing an acrylic foam precursor composition and a cell forming gas into an agitation and mixing apparatus equipped with a casing provided with a flow path through which a fluid flows, and agitation blades disposed within said casing capable of vibrating in the axial direction of said casing, forming cells within the acrylic foam precursor composition by agitating and mixing the acrylic foam precursor composition and the cell forming gas in the agitation and mixing apparatus, coating the acrylic foam precursor composition containing the cells onto a substrate, and curing the coated acrylic foam precursor composition.
    • 一种丙烯酸泡沫压敏粘合剂及其制造方法,其密度低,细胞均匀分散。 一种丙烯酸泡沫压敏粘合剂,其细胞平均直径不超过300μm,标准偏差不超过11​​5μm。 一种丙烯酸泡沫压敏粘合剂的生产方法,包括:将丙烯酸泡沫前体组合物和细胞形成气体引入搅拌和混合装置,所述搅拌和混合装置配备有设置有流体流过的流动路径的壳体,以及设置在所述 壳体,其能够在所述壳体的轴向方向上振动,通过在搅拌和混合装置中搅拌和混合丙烯酸类泡沫前体组合物和细胞形成气体,在丙烯酸泡沫前体组合物中形成细胞,涂覆含有细胞的丙烯酸类泡沫前体组合物 并固化涂覆的丙烯酸类泡沫前体组合物。
    • 97. 发明授权
    • Composition for gene introduction into cell
    • 用于基因转移到细胞中的组成
    • US06372714B1
    • 2002-04-16
    • US09402452
    • 1999-10-07
    • Kenichi TanakaHiroshi KikuchiNorio Suzuki
    • Kenichi TanakaHiroshi KikuchiNorio Suzuki
    • A61K746
    • A61K9/1272A61K48/00C12N15/88
    • The present invention is directed to a composition for gene transfer which composition contains a quaternary ammonium salt represented by formula (1): wherein A represents (wherein each of R1, R2, R3, R4 and R5, which are identical to or different from one another, represents a C9-C17 aliphatic group); X1 represents a halogen atom; and n is an integer from 1 to 10 inclusive; and a method for introducing a gene into a cell by use of the composition. The composition enables effective delivery and expression of a gene which previously could not be effectively expressed in cells due to the low ratio at which the gene is delivered into cells. Therefore, the composition is advantageously used as a gene transfer reagent or a pharmaceutical.
    • 本发明涉及一种用于基因转移的组合物,该组合物含有由式(1)表示的季铵盐:其中A表示(其中R 1,R 2,R 3,R 4和R 5各自与一个或多个相同或不同) 另一个,代表C 9 -C 17脂族基团); X1表示卤原子; n为1〜10的整数, 以及通过使用该组合物将基因导入细胞的方法。由于将基因递送到细胞中的比例低,组合物能够有效地递送和表达以前不能在细胞中表达的基因。 因此,该组合物有利地用作基因转移试剂或药物。