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91. 发明授权

US5173416A L-carnitine dehydrogenase from alcalgenes 失效
标题翻译：来自ALCALGENES的L-CARNITINE DEHYDROGENASE
公开(公告)号：US5173416A
公开(公告)日：1992-12-22
申请号：US596994
申请日：1990-10-12
申请人： Mamoru Takahashi , Kazuo Matsuura , Shinobu Nagasawa
发明人： Mamoru Takahashi , Kazuo Matsuura , Shinobu Nagasawa
IPC分类号： C12N1/20 , C12N9/04 , C12R1/05
CPC分类号： C12N9/0006 , Y10S435/822 , Y10S435/829
摘要： A new class of L-carnitine dehydrogenase is disclosed, which is stable in solution and has a residual activity of greater than 70% after one week in a pH 9.0 buffer solution at 5.degree. C., a molecular weight of 51,000.+-.6,000 daltons, a pH optimum of 9.0, a optimum temperature of 50.degree. C. and an isoelectric point of pH 5.3.+-.0.6. Also disclosed is a process for producing the new enzyme from a microorganism of the Alcaligenes genus, preferably the newly-discovered species Alcaligenes sp. No. 981 FERM BP-2570.

92. 发明授权

US5156966A L-carnitine dehydrogenase and process for its production 失效
标题翻译： L-CARNITINE脱氢酶及其生产方法
公开(公告)号：US5156966A
公开(公告)日：1992-10-20
申请号：US726200
申请日：1991-07-05
申请人： Mamoru Takahashi , Kazuo Matsuura , Shinobu Nagasawa
发明人： Mamoru Takahashi , Kazuo Matsuura , Shinobu Nagasawa
IPC分类号： C12N1/20 , C12N9/04 , C12R1/05
CPC分类号： C12N9/0006 , Y10S435/822 , Y10S435/829
摘要： An isolated L-carnitine dehydrogenase is disclosed, which is stable in solution and has a residual activity of greater than 70% after one week in a pH 9.0 buffer solution at 5.degree. C. Also disclosed is a process for producing the new enzyme from a microorganism of the Alcaligenes genus, preferably the newly-discovered species Alcaligenes sp. No. 981 FERM BP-2570.
摘要翻译：公开了一种分离的L-肉碱脱氢酶，其在溶液中是稳定的，并且在5℃的pH 9.0缓冲溶液中在一周后具有大于70％的残留活性。还公开了一种从产碱杆菌属的微生物，优选新发现的产碱杆菌属 981 FERM BP-2570。

93. 发明授权

US5116748A Process for the production of L-alanine dehydrogenase from 78-3 FERM BP-2517 失效
标题翻译：从78-3 FERM BP-2517生产L-苯胺脱氢酶的方法
公开(公告)号：US5116748A
公开(公告)日：1992-05-26
申请号：US413431
申请日：1989-09-26
申请人： Mamoru Takahashi , Shinobu Nagasawa , Shigeru Ikuta , Kazuo Matsuura
发明人： Mamoru Takahashi , Shinobu Nagasawa , Shigeru Ikuta , Kazuo Matsuura
IPC分类号： C12N1/20 , C12N9/06 , C12R1/01
CPC分类号： C12N9/0016 , C12R1/01
摘要： A process for the production of L-alanine dehydrogenase which comprises culturing an L-alanine dehydrogenase producing microorganism belonging to the genus Sporolactobacillus in a nutrient medium and isolating thus-produced L-alanine dehydrogenase from the cultured mass. The microorganism is for example Sporolactobacillus sp. 78-3 FERM BP-2517 and mutants and variants thereof having the ability to produce L-alanine dehydrogenase in recoverable amounts. This strain is a thermophile which cannot grow at 40.degree. C. but can grow at 45.degree. C. and 52.degree. C. The strain can assimilate glucose and produce lactic acid and acetic acid.

94. 发明授权

US5045619A N-alkenylcarbamate macromer 失效
标题翻译： N-链烯基氨基甲酸酯大分子单体
公开(公告)号：US5045619A
公开(公告)日：1991-09-03
申请号：US336588
申请日：1989-04-10
申请人： Nobuyuki Kuroda , Hiroshi Kobayashi , Kazuo Matsuura
发明人： Nobuyuki Kuroda , Hiroshi Kobayashi , Kazuo Matsuura
IPC分类号： C07C271/42 , C07C67/00 , C07C239/00 , C07C271/10 , C08F26/00 , C08F26/02 , C08F290/06 , H01B1/12
CPC分类号： C08F26/02 , C08F290/062
摘要： A novel N-alkenylcarbamate macromer is disclosed. The macromer can be prepared by reacting an alkenyl isocyanate with a polyalkylene glycol monoalkyl ether. When polymerized or copolymerized with other monomers, the macromer produces comb-shaped polymers useful as compatibilizing agents, matrices for polymeric solid electrolytes, etc.
摘要翻译：公开了一种新的N-链烯基氨基甲酸酯大分子单体。大分子单体可以通过烯基异氰酸酯与聚亚烷基二醇单烷基醚反应来制备。当与其他单体聚合或共聚时，大分子单体产生可用作相容剂的梳状聚合物，聚合物固体电解质的基质等。

95. 发明授权

US5026511A Process for the production of polyethylene materials 失效
标题翻译：聚乙烯材料生产工艺
公开(公告)号：US5026511A
公开(公告)日：1991-06-25
申请号：US485248
申请日：1990-02-26
申请人： Akira Sano , Hirofumi Kamiishi , Seizo Kobayashi , Kazuo Matsuura , Shigeki Yokoyama
发明人： Akira Sano , Hirofumi Kamiishi , Seizo Kobayashi , Kazuo Matsuura , Shigeki Yokoyama
IPC分类号： C08F4/64 , B29C55/00 , B29C55/18 , C08F4/60 , C08F4/685 , C08F110/00 , C08F110/02 , C08J5/18 , C08L23/06 , D01F6/04
CPC分类号： C08J5/18 , B29C55/005 , B29C55/18 , C08L23/06 , D01F6/04 , B29K2023/06 , C08J2323/06
摘要： A process for producing a polyethylene material for use in products requiring high mechanical strength and high elastic modulus is disclosed. The process involves the use of a specific class of particulate polyethylenes having an intrinsic viscosity of 5-50 dl/g in decalin at 135.degree. C. and the steps of compression molding, solvent immersing, solid-phase extruding or rolling and finally drawing the material in that order.

96. 发明授权

US4770997A Thermostable bilirubin oxidase and production process thereof 失效
标题翻译：热稳定性胆红素氧化酶及其制备方法
公开(公告)号：US4770997A
公开(公告)日：1988-09-13
申请号：US820011
申请日：1986-01-21
申请人： Eiichi Yoshino , Shigeyuki Imamura , Kazuo Matsuura , Hideo Misaki
发明人： Eiichi Yoshino , Shigeyuki Imamura , Kazuo Matsuura , Hideo Misaki
IPC分类号： C12N9/06 , C12N9/02 , C12Q1/26 , C12R1/10
CPC分类号： C12Y103/03005 , C12N9/001 , C12Q1/26 , Y10S435/836
摘要： Thermostable bilirubin oxidase having substrate specificity to at least bilirubin and capable of catalyzing a reaction in which biliverdin and water are formed from bilirubin and oxygen. It can be produced by culturing a bilirubin oxidase producing micro-organism belonging to the genus Bacillus, for example, Bacillus licheniformis and then preparing the resultant bilirubin oxidase from the cultured broth.
摘要翻译：具有对至少胆红素具有底物特异性并且能够催化由胆红素和氧形成胆碱和水的反应的热稳定性胆红素氧化酶。可以通过培养属于芽孢杆菌属的例如地衣芽孢杆菌的产生胆红素氧化酶的微生物，然后从培养的肉汤中制备所得到的胆红素氧化酶来制备。

97. 发明授权

US4518752A Process for polyolefins production 失效
标题翻译：聚烯烃生产工艺
公开(公告)号：US4518752A
公开(公告)日：1985-05-21
申请号：US551516
申请日：1983-11-15
申请人： Nobuyuki Kuroda , Toru Nakamura , Yutaka Shikatani , Kazuo Matsuura
发明人： Nobuyuki Kuroda , Toru Nakamura , Yutaka Shikatani , Kazuo Matsuura
IPC分类号： C08F4/00 , C08F4/10 , C08F4/14 , C08F4/16 , C08F4/60 , C08F4/62 , C08F10/00 , C08F4/02
CPC分类号： C08F10/00 , Y10S526/901 , Y10S526/906
摘要： A process for the homopolymerization or copolymerization of olefins is disclosed, which is carried out in the presence of an improved catalyst comprising a solid catalyst component and an organometal compound, said solid catalyst component being obtained by the reaction of: (a) a magnesium halide, (b) a compound represented by the formula: Me(OR).sub.n X.sub.z-n where Me is any of the Group I-VIII elements of the Periodic Table, excluding Al, Si, Ti and V, R is a hydrocarbon residual group having 1-24 carbon atoms, X is a halogen atom, z represents the valence of Me and n is 0
摘要翻译：公开了一种烯烃均聚或共聚合的方法，该方法在包含固体催化剂组分和有机金属化合物的改进催化剂存在下进行，所述固体催化剂组分通过以下反应获得：（a）卤化镁，（b）由Me（OR）n X z-n表示的化合物，其中Me是元素周期表中的I-VIII族元素中的任何一种，不包括Al，Si，Ti和V，R是具有 1-24个碳原子，X是卤素原子，z代表Me的价数，n是0

98. 发明授权

US4427771A Assay method for amylase activity and method of producing maltose dehydrogenase for use therein 失效
标题翻译：淀粉酶活性的测定方法和生产用于其中的麦芽糖脱氢酶的方法
公开(公告)号：US4427771A
公开(公告)日：1984-01-24
申请号：US311263
申请日：1981-10-14
申请人： Hideo Misaki , Eiji Muramatsu , Hidehiko Ishikawa , Kazuo Matsuura
发明人： Hideo Misaki , Eiji Muramatsu , Hidehiko Ishikawa , Kazuo Matsuura
IPC分类号： C12N9/04 , C12Q1/40 , C12N1/20 , C12Q1/32 , C12R1/11
CPC分类号： C12N9/0006 , C12Q1/40 , G01N2400/18 , Y10S435/837
摘要： An assay method for amylase activity in a biological specimen such as serum, saliva or urine. The enzyme amylase in the specimen is used to decompose a substrate which is a glucose polymer having a modified reducing terminal glucose residue or a cyclic glucose polymer. A component of the decomposed substrate is measured as an indication of amylase activity in the specimen. The residue may be amylose, amylopectin, starch, starch hydrolyzate, an etherified reducing terminal, an esterified reducing terminal, gluconolactone or a gluconic acid residue or its derivative. Decomposed substrate assay may be effected by contacting the same with maltose dehydrogenase and NAD or NADP, whereupon the assay is performed by measuring the amount of reduced NAD or reduced NADP, by reacting the same with reduced-form hydrogen transport colorimetric reaction reagent. This reagent may be a tetrazolium salt and diaphorase, or tetrazolium salt and phenazinemethosulfate. To remove pre-existing glucose and maltose present in the specimen, the specimen may be pretreated with alpha-glucosidase or kinase in the presence of Mg.sup.++ and ATP, the kinase being for example hexokinase. The preferred maltose dehydrogenase is produced by culturing Bacillus megaterium B-0779 FERM-P No. 5662.
摘要翻译：生物样品如血清，唾液或尿液中淀粉酶活性的测定方法。试样中的酶淀粉酶用于分解具有修饰的还原性末端葡萄糖残基或环状葡萄糖聚合物的葡萄糖聚合物的底物。测量分解的底物的组分作为样品中淀粉酶活性的指示。残基可以是直链淀粉，支链淀粉，淀粉，淀粉水解物，醚化还原末端，酯化还原末端，葡萄糖酸内酯或葡萄糖酸残基或其衍生物。分解的底物测定可以通过使其与麦芽糖脱氢酶和NAD或NADP接触来实现，因此通过使其与还原形式的氢转运比色反应试剂反应来测量还原的NAD或还原的NADP的量来进行测定。该试剂可以是四唑盐和心律黄素，或四唑鎓盐和吩嗪甲硫酸盐。为了除去样品中存在的现有葡萄糖和麦芽糖，可以在Mg ++和ATP存在下用α-葡糖苷酶或激酶预处理样品，所述激酶例如己糖激酶。优选的麦芽糖脱氢酶是通过培养巨大芽孢杆菌B-0779 FERM-P No.5662产生的。

99. 发明授权

US4384088A Process for preparing polyolefins 失效
标题翻译：聚烯烃的制备方法
公开(公告)号：US4384088A
公开(公告)日：1983-05-17
申请号：US913507
申请日：1978-06-07
申请人： Mitsuo Matsuno , Etsuo Kawamata , Nobuyuki Kuroda , Kazuo Matsuura , Mitsuji Miyoshi
发明人： Mitsuo Matsuno , Etsuo Kawamata , Nobuyuki Kuroda , Kazuo Matsuura , Mitsuji Miyoshi
IPC分类号： C08F4/62 , C08F4/64 , C08F10/00 , C08F4/02 , C08F10/02
CPC分类号： C08F10/00 , Y10S526/906
摘要： According to this invention, there is provided a process for preparing polyolefins wherein olefins are polymerized or copolymerized using as catalyst a solid component and an organometallic compound, characterized in that said solid component is a substance obtained by the copulverization of:(1) a reaction product resulting from a heat reaction of magnesium oxide and aluminum trichloride,(2) a titanium compound and/or a vanadium compound, and(3) if desired, an organic halide.
摘要翻译：根据本发明，提供了一种制备聚烯烃的方法，其中使用固体组分和有机金属化合物作为催化剂将烯烃聚合或共聚，其特征在于所述固体组分是通过共沉淀获得的物质：（1）反应由氧化镁和三氯化铝的热反应产生的产物，（2）钛化合物和/或钒化合物，和（3）如果需要，有机卤化物。

100. 发明授权

US4346173A Process for the production of acyl-Coenzyme A oxidase 失效
标题翻译：制备酰基辅酶A氧化酶的方法
公开(公告)号：US4346173A
公开(公告)日：1982-08-24
申请号：US201123
申请日：1980-10-27
申请人： Shigeru Ikuta , Shigeyuki Imamura , Hidehiko Ishikawa , Kazuo Matsuura , Masaki Takada , Hideo Misaki
发明人： Shigeru Ikuta , Shigeyuki Imamura , Hidehiko Ishikawa , Kazuo Matsuura , Masaki Takada , Hideo Misaki
IPC分类号： C12N9/02
CPC分类号： C12Y103/03006 , C12N9/001 , C12R1/06 , C12R1/645 , C12R1/66 , C12R1/865 , Y10S435/83 , Y10S435/911 , Y10S435/913 , Y10S435/942
摘要： A process for the production of acyl-Coenzyme A oxidase, comprises culturing an acyl-Coenzyme A-oxidase-producing microorganism belonging to genus Macrophomina, genus Cladosporium, genus Aspergillus, genus Monascus, genus Saccharomyces or genus Arthrobacter in a nutrient medium, and isolating the thus-formed acyl-CoA oxidase therefrom. The preferred species of microorganism are Macrophomina phaseoli ATCC 14383, Cladosporium resinae IFO 6367, Aspergillus candidus M-4815 FERM-P No. 5226, Monascus sp. M-4800 FERM-P No. 5225, Saccharomyces cerevisiae Y 0036 FERM-P No. 5174, and Arthrobacter sp. B-720 FERM-P No. 5224, respectively.
摘要翻译：一种制备酰基辅酶A氧化酶的方法，包括在营养培养基中培养属于巨噬细胞，枝孢霉属，曲霉属，红曲霉属，酿酒酵母属或节杆菌属的酰基辅酶A氧化酶微生物，由此形成的酰基辅酶A氧化酶。微生物的优选种类是Macrophomina phaseoli ATCC 14383，Cladosporium resinae IFO 6367，Aspergillus candidus M-4815 FERM-P No.5226，Monascus sp。 M-4800 FERM-P No.5225，酿酒酵母Y 0036 FERM-P No.5174和节杆菌属（Arthrobacter sp。 B-720 FERM-P No. 5224。

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