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91. 发明申请

US20060216280A1 Fibrinogen-based tissue adhesive containing an elastase inhibitor 有权
公开(公告)号：US20060216280A1
公开(公告)日：2006-09-28
申请号：US11443925
申请日：2006-05-30
申请人： Heinz Redl , Guenther Schlag , Johann Eibl
发明人： Heinz Redl , Guenther Schlag , Johann Eibl
IPC分类号： A61K38/54 , C12N9/00
CPC分类号： A61L24/106
摘要： The present invention provides a fibrinogen-based tissue adhesive which contains an elastase inhibitor.

92. 发明申请

US20060009376A1 Stable therapeutic proteins 有权
标题翻译：稳定的治疗蛋白
公开(公告)号：US20060009376A1
公开(公告)日：2006-01-12
申请号：US11155416
申请日：2005-06-17
申请人： Johann Eibl
发明人： Johann Eibl
IPC分类号： A61K38/17 , C07K14/47
CPC分类号： A61K38/37 , A61K38/36 , A61K38/363
摘要： The invention relates to storable medicaments produced from pharmaceutical active ingredient preparations which are virus safe. Said medicaments contain at least one intact therapeutic protein obtained from plasma or by means of genetic engineering, as an active pharmaceutical substance. Said active ingredient preparations contain active enzymes, especially proteases, which are either free or bound to the substrates thereof and act against the therapeutic protein(s) present.
摘要翻译：本发明涉及由病毒安全的药用活性成分制剂制备的可储存药物。所述药物含有至少一种从血浆或通过基因工程获得的完整治疗蛋白质作为活性药物。所述活性成分制剂含有活性酶，特别是蛋白酶，它们与其底物游离或结合，并且对抗存在的治疗性蛋白质。

93. 发明申请

US20050239171A1 Method for purifying factor VIII/vWF-complex by means of cation exchange chromatography 有权
标题翻译：通过阳离子交换色谱法纯化因子VIII / vWF-复合物的方法
公开(公告)号：US20050239171A1
公开(公告)日：2005-10-27
申请号：US10789562
申请日：2004-02-27
申请人： Artur Mitterer , Bernhard Fischer , Oyvind Schonberger , Kathrin Thomas-Urban , Friedrich Dorner , Johann Eibl
发明人： Artur Mitterer , Bernhard Fischer , Oyvind Schonberger , Kathrin Thomas-Urban , Friedrich Dorner , Johann Eibl
IPC分类号： A61K38/43 , A61K38/00 , A61K38/37 , A61P7/04 , C07K1/18 , C07K14/755 , C12P21/04
CPC分类号： A61K38/37 , C07K14/755
摘要： There is disclosed a method of recovering factor VIII/vWF-complex which is characterized in that factor VIII/vWF-complex from a protein solution is bound to a cation exchanger and is recovered by step-wise elution of factor VIII/vWF-complex , which particularly contains high-molecular vWF multimers, as well as a factor VIII/vWF-complex obtainable by means of cation exchange chromatography.
摘要翻译：公开了一种回收因子VIII / vWF-复合物的方法，其特征在于将来自蛋白质溶液的因子VIII / vWF-复合物结合到阳离子交换剂并通过逐步洗脱因子VIII / vWF-复合物来回收，其特别包含高分子vWF多聚体，以及通过阳离子交换层析可获得的因子VIII / vWF-络合物。

94. 发明申请

US20050192223A1 Pharmaceutical preparations and medicines capable of generating, and/or containing, thrombin 有权
标题翻译：能够产生和/或含有凝血酶的药物制剂和药物
公开(公告)号：US20050192223A1
公开(公告)日：2005-09-01
申请号：US11041165
申请日：2005-01-21
申请人： Johann Eibl
发明人： Johann Eibl
IPC分类号： A61K38/36
CPC分类号： A61K38/36 , A61K2300/00
摘要： The invention relates to a pharmaceutical active ingredient preparation for producing a medicament that contains thrombin or has a thrombin-generating capacity and compositions comprising thereof. The inventive preparation contains: (A) prothrombin obtained from plasma or by means of genetic engineering (coagulation factor II), (B) coagulation factors V, VIII, IX, X obtained from plasma or by means of genetic engineering, which can be at least partially in the activated state, and coagulation factor Xla obtained from plasma or by means of genetic engineering, and (C) phospholipids which are safe from prions and contribute to the clotting process, said phospholipids being optionally contained in liposomes.
摘要翻译：本发明涉及一种用于生产含有凝血酶或具有凝血酶生成能力的药物的药物活性成分制剂及其组合物。本发明的制剂包含：（A）从血浆或通过基因工程（凝血因子II）获得的凝血酶原，（B）从血浆或通过遗传工程获得的凝血因子V，VIII，IX，X，其可以在至少部分为活化状态，以及由血浆或通过遗传工程获得的凝血因子Xla，和（C）磷酸，其从朊病毒中是安全的并有助于凝血过程，所述磷脂任选地包含在脂质体中。

95. 发明申请

US20050162028A1 Brushless electric motor and instrument for a medical apparatus 失效
标题翻译：无刷电动机和医疗仪器仪器
公开(公告)号：US20050162028A1
公开(公告)日：2005-07-28
申请号：US10856379
申请日：2004-05-27
申请人： Richard Kardeis , Roland Sevcik , Johann Eibl , Rainer Schrock , Harald Schorghofer , Rainer MacKinger , Wolfgang Wendtner , Dieter Kobel
发明人： Richard Kardeis , Roland Sevcik , Johann Eibl , Rainer Schrock , Harald Schorghofer , Rainer MacKinger , Wolfgang Wendtner , Dieter Kobel
IPC分类号： H02K29/08 , H02K11/00 , H02K21/12
CPC分类号： H02K29/08
摘要： The invention relates to a brushless electric motor which has a rotor magnet, a coil apparatus for electromagnetically driving the rotor magnet, a rotor shaft for transmitting a rotary movement, which is firmly connected to the rotor magnet and runs through a rotation axis of the rotor magnet, and at least one electromagnetic transducer element for detection of the magnetic field of the rotor magnet, in which the at least one electromagnetic transducer element is arranged outside the axial extent of the rotor magnet with respect to the rotation axis, and is arranged essentially within the maximum radial extent of the rotor magnet. The invention also relates to an instrument for a medical, in particular a dental, apparatus having a brushless electric motor such as this.
摘要翻译：本发明涉及一种无刷电动机，其具有转子磁体，用于电磁驱动转子磁体的线圈装置，用于传递旋转运动的转子轴，其与转子磁体牢固地连接并且延伸通过转子的旋转轴线磁体和用于检测转子磁体的磁场的至少一个电磁换能器元件，其中至少一个电磁换能器元件相对于旋转轴线布置在转子磁体的轴向范围之外，并且基本上被布置在转子磁体的最大径向范围内。本发明还涉及一种用于医疗器械，特别是具有诸如此类的无刷电动机的牙科设备。

96. 发明授权

US06465170B2 Method for depleting viral and molecular pathogens in a biological material 失效
公开(公告)号：US06465170B2
公开(公告)日：2002-10-15
申请号：US09934330
申请日：2001-08-20
申请人： Johann Eibl , Friedrich Dorner , Noel Barrett , Gerhard Polsler
发明人： Johann Eibl , Friedrich Dorner , Noel Barrett , Gerhard Polsler
IPC分类号： A01N102
CPC分类号： A61L2/0011 , B01J41/20
摘要： A method for depleting viral and molecular pathogens in a biological material containing one or several biological substances to be recovered is disclosed, wherein the biological material is admixed with an organic solvent, the solvent-admixed biological material is contacted with an ion exchanger, wherein the pathogens are adsorbed on the ion exchanger material, and at least one of the biological substances to be recovered does not interact or interacts only slightly with the ion exchanger, and the ion exchanger with the pathogens adsorbed thereon is sesparated from the biological material, a virus-depleted preparation of the biological substance being recovered.

97. 发明授权

US06403556B1 Pharmaceutical preparation containing protein C and a thrombolytically active substance 失效
标题翻译：含有蛋白C和血栓溶解活性物质的药物制剂
公开(公告)号：US06403556B1
公开(公告)日：2002-06-11
申请号：US07899866
申请日：1992-06-17
申请人： Johann Eibl , Anton Philapitsch , Hans Peter Schwarz
发明人： Johann Eibl , Anton Philapitsch , Hans Peter Schwarz
IPC分类号： A01N3718
CPC分类号： C07K14/3153 , A61K38/00 , C12N9/6435 , C12N9/6456 , C12N9/6459 , C12N9/6462 , C12N9/6464 , C12Y304/21007 , C12Y304/21068 , C12Y304/21069 , C12Y304/21073 , Y10S514/802 , Y10S514/822 , Y10S514/834
摘要： A pharmaceutical preparation contains protein C and a thrombolytically active substance that does not activate protein C. This preparation prevents reocclusion usually occurring in the course of thrombolysis therapy.
摘要翻译：药物制剂含有蛋白质C和不激活蛋白质C的血栓溶解活性物质。该制剂防止通常在溶栓治疗过程中发生再闭塞。

98. 发明授权

US06228613B1 Stable factor VIII/von Willebrand factor complex 有权
标题翻译：稳定因子VIII / von Willebrand因子复合物
公开(公告)号：US06228613B1
公开(公告)日：2001-05-08
申请号：US09142768
申请日：1998-11-06
申请人： Bernhard Fischer , Artur Mitterer , Friedrich Dorner , Johann Eibl
发明人： Bernhard Fischer , Artur Mitterer , Friedrich Dorner , Johann Eibl
IPC分类号： C12P2106
CPC分类号： C07K14/755 , Y10S514/834 , Y10T436/25375
摘要： There are disclosed a stable factor VIII/vWF-complex, particularly comprising high-molecular vWF multimers, being free from low-molecular vWF molecules and from proteolytic vWF degradation products, as well as a method of producing this complex.
摘要翻译：公开了稳定的因子VIII / vWF-复合物，特别是包含不含低分子vWF分子和蛋白水解vWF降解产物的高分子vWF多聚体，以及生产该复合物的方法。

99. 发明授权

US06224862B1 Pharmaceutical preparation for treating blood coagulation disorders 有权
标题翻译：用于治疗凝血障碍的药物制剂
公开(公告)号：US06224862B1
公开(公告)日：2001-05-01
申请号：US09521219
申请日：2000-03-08
申请人： Peter Turecek , Hans-Peter Schwarz , Johann Eibl
发明人： Peter Turecek , Hans-Peter Schwarz , Johann Eibl
IPC分类号： A61K3848
CPC分类号： C12N9/6432 , A61K38/4833 , A61K38/4846 , A61K38/57 , C07K1/18 , C07K1/20 , C07K1/36 , C07K14/745 , C12N9/6429 , C12N9/647 , C12Y304/21005 , C12Y304/21006 , Y10S514/822 , A61K2300/00
摘要： There is disclosed a pharmaceutical preparation for treating blood coagulation disorders which comprises purified prothrombinase factors, in particular purified prothrombin and optionally purified factor Xa as active component.
摘要翻译：公开了一种用于治疗凝血障碍的药物制剂，其包括纯化的凝血酶原因子，特别是纯化的凝血酶原和可选地纯化的因子Xa作为活性成分。

100. 发明授权

US6165974A Pharmaceutical preparation for treating blood coagulation disorders 有权
公开(公告)号：US6165974A
公开(公告)日：2000-12-26
申请号：US245339
申请日：1999-02-05
申请人： Peter Turecek , Hans-Peter Schwarz , Johann Eibl
发明人： Peter Turecek , Hans-Peter Schwarz , Johann Eibl
IPC分类号： G01N33/86 , A61K31/435 , A61K31/60 , A61K38/00 , A61K38/36 , A61K38/43 , A61K38/48 , A61K38/55 , A61K38/57 , A61K45/00 , A61K47/48 , A61P3/14 , A61P7/02 , A61P7/04 , A61P39/02 , C07K1/18 , C07K1/20 , C07K1/36 , C07K14/745 , C12N9/64 , C12N9/74
CPC分类号： C12N9/6432 , A61K38/4833 , A61K38/4846 , A61K38/57 , C07K1/18 , C07K1/20 , C07K1/36 , C07K14/745 , C12N9/6429 , C12N9/647 , C12Y304/21005 , C12Y304/21006 , Y10S514/822 , A61K2300/00
摘要： There is disclosed a pharmaceutical preparation for treating blood coagulation disorders which comprises purified prothrombinase factors, in particular purified prothrombin and optionally purified factor Xa as active component.

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