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91. 发明授权

US5486358A Azlactone-functional polymer blends, articles produced therefrom and methods for preparing both 失效
标题翻译：吖内酯官能聚合物共混物，由其制备的制品及其制备方法
公开(公告)号：US5486358A
公开(公告)日：1996-01-23
申请号：US415730
申请日：1995-04-03
申请人： Patrick L. Coleman , Steven M. Heilmann , Steven L. Kangas , Jerald K. Rasmussen , Richard J. Rolando , Julie B. Stahl
发明人： Patrick L. Coleman , Steven M. Heilmann , Steven L. Kangas , Jerald K. Rasmussen , Richard J. Rolando , Julie B. Stahl
IPC分类号： G01N33/545 , C07D263/32 , C08F2/02 , C08K5/357 , C08L23/02 , C08L33/04 , C08L33/12 , C08L45/00 , C08L77/00 , C08L101/00 , C08L39/04 , A61K47/32 , B32B27/30
CPC分类号： C08L23/02 , C08L101/00 , C08L23/06 , C08L23/0815 , C08L23/10 , C08L77/00 , C08L2203/02 , C08L2203/16 , Y10T428/31754 , Y10T428/31935
摘要： An azlactone-functional thermoplastic composition is disclosed, The composition is a blend of an azlactone-functional composition and a thermoplastic polymer. A method of making azlactone-functional homopolymers by bulk homopolymerization is disclosed, optionally also concurrent or sequential blending of a thermoplastic polymer. A method of blending azlactone-functional compositions and thermoplastic polymers is disclosed. Molded articles coupled with biologically active substances are claimed.
摘要翻译：公开了吖内酯官能的热塑性组合物。该组合物是吖内酯官能组合物和热塑性聚合物的共混物。公开了通过本体均聚制备吖内酯官能的均聚物的方法，任选地还可以并行或顺序共混热塑性聚合物。公开了混合吖内酯官能组合物和热塑性聚合物的方法。要求具有与生物活性物质偶联的成型制品。

92. 发明授权

US5468847A Method of isolating and purifying a biomacromolecule 失效
标题翻译：分离和纯化生物大分子的方法
公开(公告)号：US5468847A
公开(公告)日：1995-11-21
申请号：US209700
申请日：1994-03-10
申请人： Steven M. Heilmann , Gary J. Drtina , Philip D. Eitzman , Louis C. Haddad , Frederick W. Hyde , Todd W. Johnson , Jerald K. Rassmussen , Michael G. Williams
发明人： Steven M. Heilmann , Gary J. Drtina , Philip D. Eitzman , Louis C. Haddad , Frederick W. Hyde , Todd W. Johnson , Jerald K. Rassmussen , Michael G. Williams
IPC分类号： G01N33/48 , A61K38/00 , A61K47/48 , B01D15/08 , B01D39/08 , B01D39/16 , C07K1/22 , C07K1/34 , C07K17/14 , C08B37/00 , C12P21/00 , G01N1/10 , C07K1/16 , B01D61/08 , C07K1/18
CPC分类号： B01D39/083 , B01D15/08 , B01D39/086 , B01D39/1623 , B01D39/18 , B01D39/2068 , C07K1/34 , B01D15/361 , B01D15/3804 , B01D2239/0407 , B01D2239/0428 , B01D2239/1291
摘要： The invention provides a method of separating a biomacromolecule which comprises the steps of providing a separation system including a filter element which comprises a composite filtration medium, the composite filtration medium comprising a filtration layer on the upstream surface of which are located insoluble stationary phase particulates, the particulates being capable of binding to a biomacromolecule or class of biomacromolecules, a reservoir containing a solution mixture comprising at least one biomacromolecule as solute, and a pump and associated tubing to form a closed loop assembly, and recirculation pumping the solution mixture through the filter cartridge so as to bind the at least one biomacromolecule to the stationary phase particulate so as to form a biomacromolecule:stationary phase particulate product. An eluting solution can be pumped through the closed loop assembly which is capable of reversing the biomacromolecule:stationary phase particulate product binding interaction so as to liberate the biomacromolecule.
摘要翻译：本发明提供了分离生物大分子的方法，其包括提供包括复合过滤介质的过滤元件的分离系统的步骤，所述复合过滤介质在其上游表面上设置有不溶性固定相颗粒的过滤层，能够结合生物大分子或一类生物大分子的颗粒，含有至少一种作为溶质的生物大分子的溶液混合物的储存器，以及泵和相关管道以形成闭环组件，以及再循环泵送溶液混合物通过过滤器以便将至少一种生物大分子结合至固定相颗粒，以便形成生物大分子：固定相颗粒产物。洗脱溶液可以泵送通过闭环组件，其能够逆转生物大分子：固定相颗粒产物结合相互作用以释放生物大分子。

93. 发明授权

US4996243A Curable acrylamido oligomer compositions with initiator, and cured products 失效
标题翻译：具有引发剂的固化丙烯酰氨基低聚物组合物和固化产物
公开(公告)号：US4996243A
公开(公告)日：1991-02-26
申请号：US465041
申请日：1990-01-16
申请人： Jerald K. Rasmussen , Steven M. Heilmann , Frederick J. Palensky
发明人： Jerald K. Rasmussen , Steven M. Heilmann , Frederick J. Palensky
IPC分类号： C08F2/50 , C08F299/02 , C09D4/00 , C09J4/00
CPC分类号： C09D4/00 , C08F299/024 , C09J4/00
摘要： A composition of matter comprising an acrylamido-acyl or methacrylamido-acyl oligomer derived from at least one nucleophilic oligomer having at least one amino-, hydroxyl-, or thiol-substituted polyoxyalkylene, polyalkyleneimine, polyester, polyolefin, polyacrylate, or polysiloxane oligomer, said nucleophilic oliogmer having a molecular weight in the range of 200 to 20,000 is disclosed. Also disclosed are free radially polymerizable monomer-containing compositions containing said oligomers as well as acrylamido- and methacrylamido-acylated polymers which are the thermal or photocured products of said oligomers. In addition, a process is disclosed for providing said acrylamido- and methacrylamido-acylated oligomers which are useful, for example, in coatings, films, printing inks, adhesives, and saturants.
摘要翻译：包含衍生自至少一种具有至少一个氨基，羟基或硫醇取代的聚氧化烯，聚亚烷基亚胺，聚酯，聚烯烃，聚丙烯酸酯或聚硅氧烷低聚物的亲核低聚物的丙烯酰氨基 - 酰基或甲基丙烯酰氨基 - 酰基低聚物的物质组合物，公开了分子量在200至20,000范围内的亲核醇。还公开了含有所述低聚物以及作为所述低聚物的热或光固化产物的丙烯酰氨基和甲基丙烯酰氨基酰化聚合物的自由的可径向聚合的含单体组合物。此外，公开了一种用于提供所述丙烯酰氨基和甲基丙烯酰氨基酰化的低聚物的方法，其可用于例如涂料，膜，印刷油墨，粘合剂和饱和物。

94. 发明授权

US4619867A Azlactone-containing pressure-sensitive adhesives 失效
公开(公告)号：US4619867A
公开(公告)日：1986-10-28
申请号：US676206
申请日：1984-11-28
申请人： Robert R. Charbonneau , Steven M. Heilmann , Jerald K. Rasmussen , Michael L. Tumey
发明人： Robert R. Charbonneau , Steven M. Heilmann , Jerald K. Rasmussen , Michael L. Tumey
IPC分类号： C09J133/08 , C08F220/10 , C08F226/06 , C09J7/02
CPC分类号： C09J133/08 , C09J2201/606 , Y10T428/2887 , Y10T428/2891
摘要： Pressure-sensitive adhesives are prepared by the simultaneous polymerization of minor amounts of at least one alkenyl azlactone monomer and at least one arylic-functional carboxylic acid monomer, or precursors thereof, with a major amount of at least one acrylic monomer. The pressure-sensitive adhesives, after application to a substrate, will significantly increase in adhesion to the resultant bonded substrate after they are in the bonded configuration.

95. 发明授权

US4485236A Azlactone-functional compounds 失效
标题翻译：吖内酯官能化合物
公开(公告)号：US4485236A
公开(公告)日：1984-11-27
申请号：US424500
申请日：1982-09-27
申请人： Jerald K. Rasmussen , Steven M. Heilmann , Frederick J. Palensky
发明人： Jerald K. Rasmussen , Steven M. Heilmann , Frederick J. Palensky
IPC分类号： C07D265/06 , C07D263/42 , C08G63/00 , C08G63/12 , C08G69/00 , C08G69/40 , C08G69/42 , C08G69/44 , C08G75/02 , C08G75/04 , C08G77/38 , C08G77/388 , C08K5/35 , C08L71/02 , C08L77/00 , C08L101/02 , C09J159/00 , C09J167/00 , C09J177/00 , C09J181/00
CPC分类号： C07D263/42 , C08G69/00 , C08G69/42
摘要： Azlactone-functional compounds, which are liquid above 20.degree. C., and their method of preparation from alkenyl azlactones and nucleophilic group-substituted compounds are disclosed. The azlactone-functional compounds of the invention cure in the presence of nucleophilic chain-extending or crosslinking agents to form linear or crosslinked polyamide resin systems.
摘要翻译：公开了20℃以上液体的吖内酯官能化合物及其由链烯基吖内酯和亲核基取代的化合物制备的方法。本发明的吖内酯官能化合物在亲核延伸链或交联剂的存在下固化以形成线性或交联的聚酰胺树脂体系。

96. 发明授权

US4379201A Multiacrylate cross-linking agents in pressure-sensitive photoadhesives 失效
标题翻译：多层丙烯酸酯交联剂在压敏光固化剂中
公开(公告)号：US4379201A
公开(公告)日：1983-04-05
申请号：US249116
申请日：1981-03-30
申请人： Steven M. Heilmann , John D. Moon
发明人： Steven M. Heilmann , John D. Moon
IPC分类号： C09J4/00 , C09J7/02 , B05D3/06
CPC分类号： C09J7/0217 , C09J4/00 , Y10T428/2809 , Y10T428/2887 , Y10T428/2891
摘要： Pressure-sensitive adhesive tape having a photopolymerized acrylate polymer adhesive which has been crosslinked by a polyacrylic-functional crosslinking monomer such as trimethyol-propane triacrylate.
摘要翻译：具有光聚合丙烯酸酯聚合物粘合剂的压敏粘合带，其通过聚丙烯酸官能的交联单体例如三甲基丙烷三丙烯酸酯交联。

97. 发明授权

US4273135A Biomedical electrode 失效
标题翻译：生物医学电极
公开(公告)号：US4273135A
公开(公告)日：1981-06-16
申请号：US940735
申请日：1978-09-08
申请人： Franklin C. Larimore , Steven M. Heilmann
发明人： Franklin C. Larimore , Steven M. Heilmann
IPC分类号： A61B5/0408 , C09J133/06 , A61B5/04
CPC分类号： A61B5/411 , A61B5/04087 , C09J133/06
摘要： An essentially dry, disposable biomedical electrode is disclosed having an improved electrically-conductive material at the interface between the electrode and the skin. The conductive material consists essentially of a cohesive, conformable, nonionic hydrophilic synthetic polymer.
摘要翻译：公开了一种基本上干燥的一次性生物医学电极，其在电极和皮肤之间的界面处具有改进的导电材料。导电材料基本上由粘合的，适形的非离子亲水性合成聚合物组成。

98. 发明授权

US4172934A Acrylic functional aminocarboxylic acids and derivatives as components of pressure sensitive adhesives 失效
公开(公告)号：US4172934A
公开(公告)日：1979-10-30
申请号：US957021
申请日：1978-11-01
申请人： Steven M. Heilmann
发明人： Steven M. Heilmann
IPC分类号： C08F220/18 , C09J7/02 , C09J133/08 , C08F220/16 , C08F220/58
CPC分类号： C09J7/0217 , C08F220/18 , C09J133/08 , C09J2201/606
摘要： High performance thermoplastic pressure sensitive adhesives are prepared by the copolymerization of N-(meth)-acryloylamino acids and acid derivatives with long-chained alkyl acrylates. The copolymers can be formulated into tapes that possess an excellent threefold balance of the necessary tape properties of tack, adhesion and cohesion.

99. 发明授权

US4074004A Pressure-sensitive adhesive tape employing moisture resistant acrylate-base copolymer adhesive 失效
标题翻译：使用防潮丙烯酸酯共聚物粘合剂的压敏胶带
公开(公告)号：US4074004A
公开(公告)日：1978-02-14
申请号：US702347
申请日：1976-07-02
申请人： George F. Bateson , Francis W. Brown , Steven M. Heilmann
发明人： George F. Bateson , Francis W. Brown , Steven M. Heilmann
IPC分类号： C09J7/02 , C09J133/04 , C09J133/08
CPC分类号： C09J7/0217 , C09J133/08 , C09J2201/606 , Y10S526/931 , Y10T428/2887 , Y10T428/2891 , Y10T428/3175 , Y10T428/31797 , Y10T428/3187 , Y10T428/31906 , Y10T428/31928
摘要： Normally tacky and pressure-sensitive adhesive tapes, labels, etc. which, when adhered to dry fibrous webs, remain firmly attached when the web and adhesive are thereafter exposed to moist conditions. These performance characteristics, which are not found when conventional pressure-sensitive adhesives are used, result from employing acrylate-based copolymer adhesives made from specific monomers and having inherent viscosities related to the monomers employed.
摘要翻译：当粘合到干燥的纤维网上时，通常粘性和压敏粘合带，标签等保持牢固地连接，然后当幅材和粘合剂暴露于潮湿条件下时。当使用常规的压敏粘合剂时，没有发现这些性能特征是由采用由特定单体制成的丙烯酸酯共聚物粘合剂，并且具有与所用单体相关的特性粘度。

100. 发明授权

US6018009A Crosslinked isocyanate functional polymer supports 失效
标题翻译：交联的异氰酸酯官能聚合物载体
公开(公告)号：US6018009A
公开(公告)日：2000-01-25
申请号：US771889
申请日：1996-12-23
申请人： Steven M. Heilmann , Gary J. Drtina , Louis C. Haddad , Frederick W. Hyde , Dean M. Moren , Robert A. Pranis
发明人： Steven M. Heilmann , Gary J. Drtina , Louis C. Haddad , Frederick W. Hyde , Dean M. Moren , Robert A. Pranis
IPC分类号： B01J31/06 , A61K47/32 , C08F20/36 , C08F212/36 , C08F220/20 , C08F220/34 , C08F220/36 , C08F220/56 , C08G18/64 , C08G18/72 , C12N11/08 , C08F26/02 , C08F126/02 , C08F226/02
CPC分类号： C08G18/728 , C08F20/36 , C08F220/36 , C08G18/6446 , C12N11/08 , Y10S530/815
摘要： Insoluble supports are prepared which possess high surface areas and efficiently dispersed isocyanate groups. These reactive supports are useful for covalently binding proteins which preferably are enzymes and provide catalysts for conducting organic reactions.
摘要翻译：制备具有高表面积和有效分散的异氰酸酯基团的不溶性载体。这些反应性支持物可用于共价结合蛋白质，其优选为酶并提供用于进行有机反应的催化剂。

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