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    • 91. 发明申请
    • Sign structure for a personal computer
    • 个人电脑的标志结构
    • US20070279893A1
    • 2007-12-06
    • US11802286
    • 2007-05-22
    • Sung-Yi YaoYen-Po Yu
    • Sung-Yi YaoYen-Po Yu
    • F21V9/16
    • G09F13/04G06F1/182
    • A sign structure for a personal computer includes a casing panel, an illuminating panel, and a sign panel. The casing panel has a least one slot opening. The illuminating panel, mounted adjacent to an exterior surface of the casing panel has at least one through opening corresponding to the slot opening, and at least one power supply connector. The sign panel mounted adjacent to an exterior side of the illuminating panel has at least one through hole corresponding to the through opening. Besides, at least part of the sign panel is transparent. Therefore, the illuminating panel of the sign structure for a personal computer of the invention can illuminate when the power is transmitted through the power supply connector to it, in order to differentiate the I/O connectors of the personal computer in low light conditions.
    • 个人计算机的标志结构包括壳体面板,照明面板和标志面板。 壳体板具有至少一个槽口。 安装在壳体面板的外表面附近的照明面板具有至少一个对应于槽口的通孔和至少一个电源连接器。 靠近照明面板的外侧安装的标志面板具有至少一个对应于通孔的通孔。 此外,符号面板的至少一部分是透明的。 因此,为了在低光条件下区分个人计算机的I / O连接器,本发明的个人计算机的符号结构的照明面板能够在通过电源连接器传输电力时照亮它。
    • 95. 发明授权
    • Use of TRIM72 as a target for muscle and heart enhancer
    • 使用TRIM72作为肌肉和心脏增强剂的目标
    • US08383602B2
    • 2013-02-26
    • US12733484
    • 2008-09-04
    • Young-Gyu KoJae-Sung YiChang-Seok Lee
    • Young-Gyu KoJae-Sung YiChang-Seok Lee
    • A61P9/00A61K31/70C12Q1/68
    • C07K14/4703A61K31/7105A61K38/00C12N15/113C12N2310/14C12Q1/6883C12Q2600/136C12Q2600/158G01N33/5008G01N33/5061
    • The present invention relates to a new use of TRIM72 as a target for muscle enhancer and heart enhancer, more particularly to a composition for enhancing muscle or heart comprising an expression or action inhibitor of TRIM72 protein. The present invention further relates to a new TRIM mutant protein inducing muscle differentiation and hypertrophy and its gene. The inventors of the present invention have identified that TRIM72 overexpression inhibits myogenesis whereas TRIM72 knockdown enhances myogenesis, and first elucidated that TRIM72 is a negative regulator of skeletal muscle differentiation. Accordingly, the inhibition of TRIM72 acts exclusively on skeletal muscle and heart muscle, but does not affect IGF-I signaling pathway in other tissues. Therefore, a drug or gene therapy using TRIM72 as a target may be helpful in treating obesity and type 2 diabetes by promoting skeletal muscle differentiation, hypertrophy and energy consumption in adipose tissue and inducing strong muscle by promoting physiological hypertrophy of heart muscle, without cancer or other side effects.
    • 本发明涉及TRIM72作为肌肉增强剂和心脏增强剂的靶的新用途,更具体地说涉及用于增强肌肉或心脏的组合物,其包含TRIM72蛋白的表达或作用抑制剂。 本发明还涉及一种诱导肌肉分化和肥大的新型TRIM突变蛋白及其基因。 本发明的发明人已经发现TRIM72过表达抑制肌细胞生成,而TRIM72敲低增强肌发生,首先阐明了TRIM72是骨骼肌分化的负调节因子。 因此,TRIM72的抑制仅在骨骼肌和心肌上起作用,但不影响其他组织中的IGF-I信号通路。 因此,使用TRIM72作为靶标的药物或基因治疗可能有助于通过促进骨骼肌分化,脂肪组织中的肥大和能量消耗以及通过促进心肌的生理肥大而诱发强力的肌肉而不致癌症或治疗肥胖和2型糖尿病 其他副作用。
    • 99. 发明授权
    • Conductive substrate structure with conductive channels formed by using a two-sided cut approach and a method for manufacturing the same
    • 具有通过使用双面切割方法形成的导电通道的导电基板结构及其制造方法
    • US08263876B2
    • 2012-09-11
    • US12649824
    • 2009-12-30
    • Bily WangSung-Yi HsiaoJack Chen
    • Bily WangSung-Yi HsiaoJack Chen
    • H05K1/11
    • B26D3/06H05K3/0044H05K3/0052H05K3/107H05K3/403Y10T29/49155Y10T29/49156Y10T83/0524
    • A conductive substrate structure includes a substrate unit, a conductive pad unit, and a conductive layer unit. The substrate unit has a top surface, a bottom surface, two opposite lateral surfaces, and a front surface. The conductive pad unit has at least two first conductive pads separated from each other and disposed on the top surface, and at least two second conductive pads separated from each other and disposed on the bottom surface. The conductive layer unit has at least two first conductive layers formed on the front surface and respectively electrically connected to two front sides of the two first conductive pads, and at least two second conductive layers respectively formed on the two opposite lateral surfaces and respectively electrically connected to two opposite lateral sides of the two second conductive pads. The two first conductive layers are respectively electrically connected with the two second conductive layers.
    • 导电基板结构包括基板单元,导电焊盘单元和导电层单元。 基板单元具有顶表面,底表面,两个相对的侧表面和前表面。 导电焊盘单元具有至少两个彼此分离并设置在顶表面上的第一导电焊盘,以及至少两个彼此分离并设置在底表面上的第二导电焊盘。 导电层单元具有形成在前表面上并分别电连接到两个第一导电焊盘的两个前侧的至少两个第一导电层,以及分别形成在两个相对的侧表面上并分别电连接的至少两个第二导电层 到两个第二导电焊盘的两个相对的侧面。 两个第一导电层分别与两个第二导电层电连接。