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    • 4. 发明授权
    • DNA base sequencer
    • DNA碱基测序仪
    • US06284119B1
    • 2001-09-04
    • US09385025
    • 1999-08-30
    • Hiroaki MachidaYusuke MiyazakiMitsuyoshi Koizumi
    • Hiroaki MachidaYusuke MiyazakiMitsuyoshi Koizumi
    • G01N2726
    • G01N27/44721
    • A DNA base sequencer including a gel electrophoretic means having tracks for electrophoresing fluorophore-labelled DNA fragments, a laser diode as a light source for illuminating said tracks with exciting laser light and a CCD sensor for detecting the fluorescence emitted from the illuminated DNA fragments, the laser diode has a control unit including a Peltier device for controlling the temperature of the laser diode, a Peltier device temperature setting generating means having a processor and a memory, and a temperature control circuit that generates a drive current to the Peltier device for controlling its temperature. The CCD sensor receives part of the exciting light from the laser diode as stray light and detects its wavelength. The Peltier device temperature setting generating means is such that, in accordance with the wavelength of stray light as detected periodically with said CCD sensor according to the program stored in said memory, it calculates a corrective value that adjusts the detected wavelength of stray light to the desired wavelength of exciting light that corresponds to the desired temperature setting and that an appropriate temperature setting signal is generated on the basis of said corrective value and the desired temperature setting and sent to the Peltier device temperature control circuit.
    • 一种DNA碱基测序仪,包括具有用于电泳荧光团标记的DNA片段的轨道的凝胶电泳装置,激光二极管作为用激发激光照射所述轨道的光源和用于检测从照射的DNA片段发出的荧光的CCD传感器, 激光二极管具有包括用于控制激光二极管的温度的珀耳帖装置的控制单元,具有处理器和存储器的珀尔帖装置温度设定发生装置,以及向珀尔帖装置产生驱动电流以控制其的存储器的温度控制电路 温度。 CCD传感器接收来自激光二极管的激光的一部分作为杂散光并检测其波长。 珀耳帖装置温度设定发生装置使得根据存储在所述存储器中的程序与所述CCD传感器周期性地检测的杂散光的波长,计算校正值,该校正值将检测到的杂散光波长调整到 对应于所需温度设定的激励光的期望波长,以及基于所述校正值和期望温度设定产生适当的温度设定信号,并发送到珀尔帖器件温度控制电路。
    • 6. 发明授权
    • Detachable lens block and video camera system including the same
    • 可拆卸镜头块和摄像机系统包括相同
    • US06172709B2
    • 2001-01-09
    • US08990089
    • 1997-12-12
    • Shiro YamanoMitsuyoshi KoizumiMakoto AmanoAkira Tamura
    • Shiro YamanoMitsuyoshi KoizumiMakoto AmanoAkira Tamura
    • H04N5232
    • H04N5/23209H04N5/23212
    • A video camera system comprises a lens block and a camera block which are attachable and detachable through a block coupling mechanism to and from each other. The detachable lens block incorporates a focus lens drive mechanism for driving a focus lens and an autofocus control section for executing autofocus control. The autofocus control section receives a composite video signal obtained by processing a video signal from an image pickup device in a signal processing section of the camera block. The autofocus control section produces a focus control signal on the basis of the composite video signal to control the focus lens drive mechanism for the execution of the autofocus control. In addition, the detachable lens block is composed of an iris drive mechanism for optically adjusting an aperture of a lens and an autoiris control section for automatically controlling the iris drive mechanism, so that automatic iris control is executed on the basis of the composite video signal outputted from the camera block. This video camera system can decrease the number of connecting lines to be provided between the detachable lens block and the camera block.
    • 摄像机系统包括透镜块和相机块,其可通过块耦合机构彼此附接和拆卸。 可拆卸透镜块包括用于驱动聚焦透镜的聚焦透镜驱动机构和用于执行自动对焦控制的自动对焦控制部。 自动对焦控制部分接收通过处理来自相机块的信号处理部分中的图像拾取装置的视频信号而获得的复合视频信号。 自动对焦控制部分根据复合视频信号产生聚焦控制信号,以控制用于执行自动对焦控制的聚焦透镜驱动机构。 此外,可拆卸透镜块由用于光学调节透镜孔径的光圈驱动机构和用于自动控制光圈驱动机构的自动控制部分组成,从而基于复合视频信号执行自动光圈控制 从相机块输出。 该摄像机系统可以减少可拆卸透镜块和相机块之间提供的连接线的数量。
    • 7. 发明授权
    • Method and apparatus for detecting abnormal patterns
    • 用于检测异常模式的方法和装置
    • US4952058A
    • 1990-08-28
    • US184787
    • 1988-04-22
    • Minori NoguchiHiroaki ShishidoMitsuyoshi Koizumi
    • Minori NoguchiHiroaki ShishidoMitsuyoshi Koizumi
    • G01N21/94G01N21/956G03F7/20
    • G03F7/70358G01N21/94G01N21/956G01N2021/8845G01N2021/95676G01N21/95623
    • A system for detecting abnormal patterns in a surface pattern on the surface of a sample wherein, when the abnormal pattern has a portion smaller than the surface pattern, the light for illuminating the sample is stopped down to an opening so that the abnormal pattern can be distinguished over the surface pattern, the surface pattern is limited to a predetermined opening by the illumination light to form an image on a detector, and the surface pattern detected by the detector is processed to detect the abnormal pattern in the surface pattern. Further, the plurality of light rays having good directivity are illuminated onto a point on the surface of the sample from dissimilar directions maintaining a predetermined angle of incidence, the detect signals are separated to be corresponded to said light rays, and the above processing is carried out to enhance the precision of detection.
    • 一种用于检测样品表面上的异常图案的系统,其中当异常图案具有小于表面图案的部分时,用于照亮样品的光被停止到开口,使得异常图案可以 区分表面图案,通过照明光将表面图案限于预定的开口,以在检测器上形成图像,并且处理由检测器检测的表面图案以检测表面图案中的异常图案。 此外,具有良好方向性的多个光线沿保持预定入射角的不同方向被照射在样品表面上的点上,检测信号被分离成与所述光线相对应,并且进行上述处理 出来提高检测精度。