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1. 发明申请

US20050083160A1 Insulation system for oil filled environments 审中-公开
标题翻译：充油环境的绝缘系统
公开(公告)号：US20050083160A1
公开(公告)日：2005-04-21
申请号：US10686290
申请日：2003-10-15
申请人： George Gao , Cuve Reed , Thangavelu Asokan , Paul Siemers , Santanu Singha
发明人： George Gao , Cuve Reed , Thangavelu Asokan , Paul Siemers , Santanu Singha
IPC分类号： H01F27/32 , H01F27/10
CPC分类号： H01F27/321 , H01F27/324
摘要： An insulation system for an oil filled environment having a plurality of insulating units, each of the plurality of insulating units including a first layer of insulating material and a second layer of insulating material. At least one of the first and second layers includes a polymeric material. The insulating units are positioned with respect to each other such that the second layer of one insulating unit is adjacent to the first layer of another insulating unit.
摘要翻译：一种用于充油环境的绝缘系统，具有多个绝缘单元，所述多个绝缘单元中的每一个包括第一绝缘材料层和第二绝缘材料层。第一层和第二层中的至少一层包括聚合材料。绝缘单元相对于彼此定位，使得一个绝缘单元的第二层与另一绝缘单元的第一层相邻。

2. 发明申请

US20050016658A1 Composite coatings for ground wall insulation in motors, method of manufacture thereof and articles derived therefrom 审中-公开
标题翻译：用于电机中的接地壁绝缘的复合涂层，其制造方法和由其衍生的制品
公开(公告)号：US20050016658A1
公开(公告)日：2005-01-27
申请号：US10627480
申请日：2003-07-24
申请人： Thangavelu Asokan , George Gao , Rajesh Ghosh
发明人： Thangavelu Asokan , George Gao , Rajesh Ghosh
IPC分类号： H02K3/30 , H02K3/32 , H02K3/40 , H01B13/06
CPC分类号： H02K3/40 , H02K3/30 , H02K3/32
摘要： An article comprises a bobbin wire; an electrically insulating backing disposed upon the bobbin wire; a mica paper disposed upon the electrically insulating backing and wound around the backing; and a silicone coating disposed upon the electrically insulating backing. A method of manufacturing an article comprises disposing an electrically insulating backing upon a bobbin wire; disposing mica paper upon the electrically insulating backing; and coating the mica paper with a silicone coating.
摘要翻译：一种制品包括线架; 布置在线轴上的电绝缘背衬; 设置在电绝缘背衬上并缠绕在背衬上的云母纸; 以及设置在电绝缘背衬上的硅氧烷涂层。制造物品的方法包括将电绝缘背衬设置在线轴上; 将云母纸放置在电绝缘背衬上; 并用硅胶涂覆云母纸。

3. 发明申请

US20060093613A1 Soluble T cell receptor 审中-公开
标题翻译：可溶性T细胞受体
公开(公告)号：US20060093613A1
公开(公告)日：2006-05-04
申请号：US11167773
申请日：2005-06-27
申请人： Bent Jakobsen , John Bell , George Gao , Benjamin Willcox , Jonathan Boulter
发明人： Bent Jakobsen , John Bell , George Gao , Benjamin Willcox , Jonathan Boulter
IPC分类号： C07K14/74 , C07H21/04 , C12P21/06 , A61K39/00 , C12N15/74
CPC分类号： G01N33/56977 , A61K38/00 , A61K47/6425 , C07K14/7051 , C07K19/00 , C07K2319/00 , C07K2319/02
摘要： The present invention relates to a recombinant soluble T cell receptor. The T cell receptor (TCR) is refolded and comprises a recombinant TCR α or γ chain extracellular domain having a first heterologous C-terminal dimerization peptide; and a recombinant TCR β or δ chain extracellular domain having a second C-terminal dimerization peptide which is specifically heterodimerized with the first dimerization peptide to form a heterodimerization domain, which may be a coiled coil domain. The invention also provides nucleic acid sequences encoding the recombinant TCR and a method for producing the recombinant TCR. The TCR may be labelled with a detectable label so as to enable the detection of specific MHC-peptide complexes. Alternatively, it can be linked to a therapeutic agent such as a cytotoxic agent or an immunostimulating agent so as to deliver such an agent to the site of a specific MHC-peptide complex.
摘要翻译：本发明涉及重组可溶性T细胞受体。 T细胞受体（TCR）被重折叠并且包含具有第一异源C末端二聚化肽的重组TCRα或γ链细胞外结构域; 和具有第二C末端二聚化肽的重组TCRβ或δ链胞外结构域，其与第一二聚化肽特异性二聚化形成异源二聚化结构域，其可以是卷曲螺旋结构域。本发明还提供了编码重组TCR的核酸序列和用于产生重组TCR的方法。可以用可检测的标记物标记TCR，以便能够检测特异性的MHC-肽复合物。或者，其可以与治疗剂例如细胞毒性剂或免疫刺激剂连接，以便将这种药物递送到特定MHC-肽复合物的位点。

4. 发明申请

US20050142349A1 Composite coatings for groundwall insulation, method of manufacture thereof and articles derived therefrom 有权
标题翻译：用于地墙绝缘的复合涂层，其制造方法和由其衍生的制品
公开(公告)号：US20050142349A1
公开(公告)日：2005-06-30
申请号：US10747725
申请日：2003-12-29
申请人： Patricia Irwin , Luana Iorio , George Gao , Yang Cao
发明人： Patricia Irwin , Luana Iorio , George Gao , Yang Cao
IPC分类号： B32B15/20 , B32B25/20 , B32B27/20 , B32B27/34 , C08K3/22 , B32B5/16 , B05D1/02 , B05D1/18 , B05D1/28 , B05D3/02 , B05D7/00 , B32B27/00
CPC分类号： B32B27/34 , B32B15/20 , B32B25/20 , B32B27/20 , C08K3/22 , Y10T428/25 , Y10T428/251 , Y10T428/256 , Y10T428/257 , Y10T428/258 , Y10T428/26 , Y10T428/269 , Y10T428/31663
摘要： Disclosed herein is an article comprising an electrical component; and an electrically insulating layer disposed upon the electrical component, wherein the electrically insulating layer comprises a thermosetting polymer and a nanosized filler. Disclosed herein too is a method of manufacturing an article comprising disposing an electrically insulating layer upon an electrical component, wherein the electrically insulating layer comprises a thermosetting polymer and a nanosized filler; and curing the thermosetting polymer.
摘要翻译：本文公开了包含电气部件的物品; 以及设置在所述电气部件上的电绝缘层，其中所述电绝缘层包含热固性聚合物和纳米尺寸填料。本文还公开了一种制造物品的方法，包括在电气部件上设置电绝缘层，其中所述电绝缘层包含热固性聚合物和纳米尺寸填料; 并固化热固性聚合物。

5. 发明授权

US07803457B2 Composite coatings for groundwall insulation, method of manufacture thereof and articles derived therefrom 有权
标题翻译：用于地墙绝缘的复合涂层，其制造方法和由其衍生的制品
公开(公告)号：US07803457B2
公开(公告)日：2010-09-28
申请号：US10747725
申请日：2003-12-29
申请人： Patricia Chapman Irwin , Luana Emiliana Iorio , George Gao , Yang Cao
发明人： Patricia Chapman Irwin , Luana Emiliana Iorio , George Gao , Yang Cao
IPC分类号： B32B5/16 , B32B15/08 , B32B19/02 , B05D3/02 , B05D5/12 , B05D1/02 , B05D1/18 , B05D1/28
CPC分类号： B32B27/34 , B32B15/20 , B32B25/20 , B32B27/20 , C08K3/22 , Y10T428/25 , Y10T428/251 , Y10T428/256 , Y10T428/257 , Y10T428/258 , Y10T428/26 , Y10T428/269 , Y10T428/31663
摘要： Disclosed herein is an article comprising an electrical component; and an electrically insulating layer disposed upon the electrical component, wherein the electrically insulating layer comprises a thermosetting polymer and a nanosized filler. Disclosed herein too is a method of manufacturing an article comprising disposing an electrically insulating layer upon an electrical component, wherein the electrically insulating layer comprises a thermosetting polymer and a nanosized filler; and curing the thermosetting polymer.
摘要翻译：本文公开了包含电气部件的物品; 以及设置在所述电气部件上的电绝缘层，其中所述电绝缘层包含热固性聚合物和纳米尺寸填料。本文还公开了一种制造物品的方法，包括在电气部件上设置电绝缘层，其中所述电绝缘层包含热固性聚合物和纳米尺寸填料; 并固化热固性聚合物。

6. 发明申请

US20070191278A1 CD8 AS AN INHIBITOR OF THE CELLULAR IMMUNE SYSTEM 审中-公开
标题翻译： CD8作为细胞免疫系统的抑制剂
公开(公告)号：US20070191278A1
公开(公告)日：2007-08-16
申请号：US11696301
申请日：2007-04-04
申请人： Bent Jakobsen , George Gao , Ulrich Gerth , Andrew Sewell
发明人： Bent Jakobsen , George Gao , Ulrich Gerth , Andrew Sewell
IPC分类号： A61K38/17
CPC分类号： C07K14/70517 , A61K38/00 , C07K2319/00
摘要： This invention is directed to a method for inhibiting cytotoxic T lymphocyte (CTL) activity in which soluble CD8 is used as the inhibitor. The invention is further directed to soluble forms of the CD8 molecule which can be administered to a patient. The method of this invention is particularly useful for immunosuppressive therapy in which inhibition of CTL activity is desirable, for example, in patients undergoing transplantation.
摘要翻译：本发明涉及一种抑制细胞毒性T淋巴细胞（CTL）活性的方法，其中使用可溶性CD8作为抑制剂。本发明还涉及可以给予患者的CD8分子的可溶形式。本发明的方法特别适用于抑制CTL活性的免疫抑制治疗，例如在接受移植的患者中。

7. 发明申请

US20060053620A1 Flexible stator bars 审中-公开
标题翻译：柔性定子线棒
公开(公告)号：US20060053620A1
公开(公告)日：2006-03-16
申请号：US11265563
申请日：2005-11-02
申请人： Yu Wang , George Gao , Evangelos Laskaris , Martin Lee , Kiruba Sivasubramaniam
发明人： Yu Wang , George Gao , Evangelos Laskaris , Martin Lee , Kiruba Sivasubramaniam
IPC分类号： H02K15/14
CPC分类号： H02K3/14 , Y10T29/49009 , Y10T29/49012
摘要： A flexible stator bar generally includes a stranded conductor having a rectangular shaped cross sectional profile, wherein the stranded conductor comprises a plurality of wires having a gauge dimension effective to impart flexibility; and a thermoplastic elastomeric insulating material disposed about the stranded conductor. Also disclosed herein are processes for fabricating the flexible stator bar, which generally comprises depositing a thermoplastic elastomeric insulating material onto the flexible stranded conductor, which can be flexibly oriented into a desired position, thereby improving dimensional control relative to Roebel-type stator bars. The insulated flexible stranded conductor may then be coated with a B-stage epoxy or the like and cured to form the final shape after assembly within the desired electrical machine application.
摘要翻译：柔性定子棒通常包括具有矩形横截面轮廓的绞合导体，其中绞合导体包括具有有助于赋予柔性的尺寸尺寸的多根线; 以及围绕所述绞合导体设置的热塑性弹性体绝缘材料。此处还公开了制造柔性定子棒的方法，其通常包括将热塑性弹性体绝缘材料沉积到柔性绞合导体上，柔性绞合导体可以灵活地定向到所需位置，从而改善相对于Roebel型定子线棒的尺寸控制。然后可以将绝缘的柔性绞合导体涂覆在B级环氧树脂等上，并在组装后在所需的电机应用中固化以形成最终形状。

8. 发明申请

US20050077075A1 Flexible stator bars 审中-公开
标题翻译：柔性定子线棒
公开(公告)号：US20050077075A1
公开(公告)日：2005-04-14
申请号：US10684186
申请日：2003-10-09
申请人： Yu Wang , George Gao , Evangelos Laskaris , Martin Lee , Kiruba Sivasubramaniam
发明人： Yu Wang , George Gao , Evangelos Laskaris , Martin Lee , Kiruba Sivasubramaniam
IPC分类号： H02K3/04 , H02K3/14 , H02K3/38 , H02K15/04 , H02K15/12 , H01B5/08
CPC分类号： H02K3/14 , Y10T29/49009 , Y10T29/49012
摘要： A flexible stator bar generally includes a stranded conductor having a rectangular shaped cross sectional profile, wherein the stranded conductor comprises a plurality of wires having a gauge dimension effective to impart flexibility; and a thermoplastic elastomeric insulating material disposed about the stranded conductor. Also disclosed herein are processes for fabricating the flexible stator bar, which generally comprises depositing a thermoplastic elastomeric insulating material onto the flexible stranded conductor, which can be flexibly oriented into a desired position, thereby improving dimensional control relative to Roebel-type stator bars. The insulated flexible stranded conductor may then be coated with a B-stage epoxy or the like and cured to form the final shape after assembly within the desired electrical machine application.
摘要翻译：柔性定子棒通常包括具有矩形横截面轮廓的绞合导体，其中绞合导体包括具有有助于赋予柔性的尺寸尺寸的多根线; 以及围绕所述绞合导体设置的热塑性弹性体绝缘材料。此处还公开了制造柔性定子棒的方法，其通常包括将热塑性弹性体绝缘材料沉积到柔性绞合导体上，柔性绞合导体可以灵活地定向到所需位置，从而改善相对于Roebel型定子线棒的尺寸控制。然后可以将绝缘的柔性绞合导体涂覆在B级环氧树脂等上，并在组装后在所需的电机应用中固化以形成最终形状。

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