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1. 发明专利

CA2627780A1 METHOD FOR INCREASING THE TOTAL OIL CONTENT IN OIL PLANTS 未知
公开(公告)号：CA2627780A1
公开(公告)日：2007-05-10
申请号：CA2627780
申请日：2006-11-06
申请人： BASF PLANT SCIENCE GMBH , MAX PLANCK GESELLSCHAFT
发明人： GEIGENBERGER PETER , WALDECK PETER , VIGEOLAS HELENE , STITT MARK , BAUER JOERG , ZANK THORSTEN , OSWALD OLIVER
IPC分类号： C12N15/82 , C12N9/04
摘要： The invention relates to methods of increasing the total oil content and/or the glycerol 3-phosphate content in transgenic oil crop plants which comprise at least 20% by weight of oleic acid based on the total fatty acid content, preferably in plant seeds, by expressing glycerol 3-phosphate dehydrogenases (G3PDHs) from yeasts, preferably from Saccharomyces cerevisiae. The oil and/or the free fatty acids obtained in the process are advantageously added to polymers, foodstuffs, feedstuffs, cosmetics, pharmaceuticals or products with industrial applications.

2. 发明专利

BRPI0618295A2 未知
公开(公告)号：BRPI0618295A2
公开(公告)日：2011-08-23
申请号：BRPI0618295
申请日：2006-11-06
申请人： MAX PLANCK GESELLSCHAFT , BASF PLANT SCIENCE GMBH
发明人： ZANK THORSTEN , OSWALD OLIVER , BAUER JOERG , VIGEOLAS HELENE , GEIGENBERGER PETER , WALDECK PETER , STITT MARK
IPC分类号： C12N15/82 , C12N9/04
摘要： The invention relates to methods of increasing the total oil content and/or the glycerol 3-phosphate content in transgenic oil crop plants which comprise at least 20% by weight of oleic acid based on the total fatty acid content, preferably in plant seeds, by expressing glycerol 3-phosphate dehydrogenases (G3PDHs) from yeasts, preferably from Saccharomyces cerevisiae. The oil and/or the free fatty acids obtained in the process are advantageously added to polymers, foodstuffs, feedstuffs, cosmetics, pharmaceuticals or products with industrial applications.

3. 发明专利

AU2006310703A1 Method for increasing the total oil content in oil plants 未知
公开(公告)号：AU2006310703A1
公开(公告)日：2007-05-10
申请号：AU2006310703
申请日：2006-11-06
申请人： BASF PLANT SCIENCE GMBH , MAX PLANCK GESELLSCHAFT
发明人： OSWALD OLIVER , WALDECK PETER , STITT MARK , GEIGENBERGER PETER , ZANK THORSTEN , BAUER JORG , VIGEOLAS HELENE
IPC分类号： C12N15/82 , C12N9/04
摘要： The invention relates to methods of increasing the total oil content and/or the glycerol 3-phosphate content in transgenic oil crop plants which comprise at least 20% by weight of oleic acid based on the total fatty acid content, preferably in plant seeds, by expressing glycerol 3-phosphate dehydrogenases (G3PDHs) from yeasts, preferably from Saccharomyces cerevisiae. The oil and/or the free fatty acids obtained in the process are advantageously added to polymers, foodstuffs, feedstuffs, cosmetics, pharmaceuticals or products with industrial applications.

4. 发明专利

JP2020089368A トランスジェニック生物における多不飽和脂肪酸の製造方法审中-公开
公开(公告)号：JP2020089368A
公开(公告)日：2020-06-11
申请号：JP2020000076
申请日：2020-01-06
申请人： BASF PLANT SCIENCE GMBH
发明人： ZANK THORSTEN , BAUER JOERG , CIRPUS PETRA , ABBADI AMINE , HEINZ ERNST , QIU XIAO , VRINTEN PATRICIA , SPERLING PETRA , DOMERGUE FREDERIC , MEYER ASTRID , KIRSCH JELENA
IPC分类号： C12N15/53 , A01H5/00 , A01K67/027 , A23D9/00 , A23K20/158 , A23L33/105 , A23L33/115 , A61K8/36 , A61K8/97 , A61K31/201 , A61K31/202 , A61K36/00 , A61P3/06 , A61P9/00 , A61P9/04 , A61P9/12 , A61P19/02 , A61P29/00 , A61P37/02 , A61Q1/00 , A61Q19/00 , C11B1/02 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/02 , C12N9/10 , C12N15/63 , C12N15/82 , C12P7/64
摘要：【課題】生物における多不飽和脂肪酸の製造方法、及び、長鎖多不飽和脂肪酸の含量が上昇した油及び/又はトリアシルグリセリドの製造方法の提供。【解決手段】有利には、タラッシオシラ、ユーグレナ又はオストレオコッカスに由来する、Δ5—エロンガーゼ活性、さらにはΔ6—デサチュラーゼ、Δ5—デサチュラーゼ、Δ4—デサチュラーゼ、Δ12—デサチュラーゼ及び/又はΔ6—エロンガーゼ活性を有するポリペプチドをコードする核酸を生物に導入することによる、生物における多不飽和脂肪酸の製造方法。トランスジェニック生物は、好ましくは、トランスジェニック植物又はトランスジェニック微生物である。【選択図】なし

5. 发明专利

JP2014128269A Method for production of multiply-unsaturated fatty acids in transgenic organisms 有权
标题翻译：在转基因生物中生产多余不饱和脂肪酸的方法
公开(公告)号：JP2014128269A
公开(公告)日：2014-07-10
申请号：JP2013270709
申请日：2013-12-27
申请人： Basf Plant Science Gmbh , ビーエーエスエフプラントサイエンスゲーエムベーハー
发明人： ZANK THORSTEN , BAUER JOERG , CIRPUS PETRA , ABBADI AMINE , HEINZ ERNST , QIU XIAO , VRINTEN PATRICIA , SPERLING PETRA , DOMERGUE FREDERIC , MEYER ASTRID , KIRSCH JELENA
IPC分类号： C12N15/09 , A01H5/00 , A01K67/027 , A23D9/00 , A23K1/16 , A23L1/30 , A61K8/36 , A61K8/37 , A61K31/202 , A61K31/232 , A61P3/06 , C11B1/02 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/02 , C12N9/10 , C12N15/82 , C12P7/64
CPC分类号： C12N15/8247 , A23D9/00 , A23D9/02 , A23L33/115 , A23V2002/00 , C11B1/00 , C12N9/0071 , C12N9/0083 , C12N9/0093 , C12N9/1029 , C12P7/6409 , C12P7/6427 , C12P7/6463 , C12P7/6472 , C12Y114/19 , C12Y114/19003 , C12Y203/01199 , Y02P20/52
摘要： PROBLEM TO BE SOLVED: To provide a method for producing multiply-unsaturated fatty acids in an organism into which nucleic acids have been introduced, the nucleic acids encoding polypeptides with Δ-5 elongase activity.SOLUTION: The method for the production of an oil and/or triacylglyceride which has increased content of long chain multiply-unsaturated fatty acids employs a vector with an isolated nucleic acid sequence encoding a polypeptide having Δ-6 desaturase, a Δ-5 desaturase, Δ-4 desaturase and/or Δ-6 elongase activity derived from Thalassiosira, Euglena, or Ostreococcus, and enzymes of an introduced transgenic organism: a microorganism, a nonhuman animal or a plant.
摘要翻译：要解决的问题：提供一种在已经引入了核酸的生物体中生产多不饱和脂肪酸的方法，编码具有＆Dgr-5延伸酶活性的多肽的核酸。解决方案：生产油的方法具有增加的长链多不饱和脂肪酸含量的甘油三酯和/或三酰基甘油酯使用具有分离的核酸序列的载体，所述分离的核酸序列编码具有＆Dgr; -6去饱和酶，＆Dgr; -5去饱和酶，Dgr-4去饱和酶和/ 衍生自Thalassiosira，Euglena或Ostreococcus的延长酶活性和引入的转基因生物的酶：微生物，非人动物或植物。

6. 发明专利

JP2011087578A Method for production of multiple-unsaturated fatty acid in transgenic organism 审中-公开
标题翻译：在转基因生物中生产多种不饱和脂肪酸的方法
公开(公告)号：JP2011087578A
公开(公告)日：2011-05-06
申请号：JP2010232883
申请日：2010-10-15
申请人： Basf Plant Science Gmbh , ビーエーエスエフプラントサイエンスゲーエムベーハー
发明人： ZANK THORSTEN , BAUER JOERG , CIRPUS PETRA , ABBADI AMINE , HEINZ ERNST , QIU XIAO , VRINTEN PATRICIA , SPERLING PETRA , DOMERGUE FREDERIC , MEYER ASTRID , KIRSCH JELENA
IPC分类号： C12N15/09 , A01H5/00 , A01K67/027 , A23D9/00 , A23L1/30 , A61K8/36 , A61K8/37 , A61K31/202 , A61K31/232 , A61P3/06 , C11B1/02 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/02 , C12N9/10 , C12N15/82 , C12P7/64
CPC分类号： C12N15/8247 , A23D9/00 , A23D9/02 , A23L33/115 , A23V2002/00 , C11B1/00 , C12N9/0071 , C12N9/0083 , C12N9/0093 , C12N9/1029 , C12P7/6409 , C12P7/6427 , C12P7/6463 , C12P7/6472 , C12Y114/19 , C12Y114/19003 , C12Y203/01199 , Y02P20/52
摘要： PROBLEM TO BE SOLVED: To provide a method for producing a multiple-unsaturated fatty acid in an organism, into which a nucleic acid coding for a polypeptide having Δ-5 elongase activity is introduced. SOLUTION: There are provided a nucleic acid sequence coding for Δ-6 desaturase, Δ-5 desaturase, Δ-4 desaturase and/or Δ-6 elongase activity and derived from Thalassiosira, Euglena or Ostreococcus, and a genetic construction containing the nucleic acid sequence. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供在生物体中制备多不饱和脂肪酸的方法，其中引入编码具有Δ-5延伸酶活性的多肽的核酸。解决方案：提供了编码Δ-6去饱和酶，Δ-5去饱和酶，Δ-4去饱和酶和/或Δ-6延伸酶活性的核酸序列，并且衍生自海水藻，欧洲淋巴细胞球菌或油球藻，以及含有核酸序列。版权所有（C）2011，JPO＆INPIT

7. 发明申请

WO2005063995A3 SUGAR AND LIPID METABOLISM REGULATORS IN PLANTS VI 审中-公开
标题翻译：植物中的糖和脂肪代谢调节剂六
公开(公告)号：WO2005063995A3
公开(公告)日：2005-10-20
申请号：PCT/IB2004004251
申请日：2004-12-22
申请人： BASF PLANT SCIENCE GMBH , OSWALD OLIVER , BAUER JORG , ZANK THORSTEN
发明人： OSWALD OLIVER , BAUER JORG , ZANK THORSTEN
IPC分类号： C12N15/82 , A01H5/00
CPC分类号： C12N15/8247 , C12N15/8245
摘要： Isolated nucleic acids and proteins associated with lipid and sugar metabolism regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana, Brassica napus, and Helianthus annuus are provided. The nucleic acids and proteins are used in methods of producing transgenic plants and modulating levels of seed storage compounds. Preferably, the seed storage compounds are lipids, fatty acids, starches, or seed storage proteins.
摘要翻译：提供了与脂质和糖代谢调节相关的分离的核酸和蛋白质。特别地，提供脂质代谢蛋白（LMP）和编码来自拟南芥，甘蓝型油菜和向日葵的核酸。核酸和蛋白质用于产生转基因植物和调节种子储存化合物水平的方法中。优选地，种子储存化合物是脂质，脂肪酸，淀粉或种子储存蛋白。

8. 发明申请

WO2009027335A3 POLYPEPTIDES, SUCH AS LIPASES, CAPABLE OF ALTERING THE SEED STORAGE CONTENT IN TRANSGENIC PLANTS 审中-公开
标题翻译：多糖，如转基因，能够改变转基因植物中的种子储存内容
公开(公告)号：WO2009027335A3
公开(公告)日：2009-05-28
申请号：PCT/EP2008061014
申请日：2008-08-22
申请人： BASF PLANT SCIENCE GMBH , ZANK THORSTEN , OSWALD OLIVER , WETJEN TOM
发明人： ZANK THORSTEN , OSWALD OLIVER , WETJEN TOM
IPC分类号： C12N15/82 , C07K14/415
CPC分类号： C12N15/8247 , C12N9/18
摘要： This invention relates generally to nucleic acid sequences encoding proteins that are related to the presence of seed storage compounds in plants. More specifically, the present invention relates to nucleic acid sequences encoding polypeptides being capable of altering the seed storage content and, in particular, oil, lipid and fatty acid metabolism regulator proteins and the use of these sequences in transgenic plants. In particular, the invention is directed to methods for manipulating seed storage compounds in plants and seeds. The invention further relates to methods of using these novel plant polypeptides to stimulate plant growth and/or to increase yield and/or composition of seed storage compounds.
摘要翻译：本发明一般涉及编码与种子储存化合物在植物中的存在有关的蛋白质的核酸序列。更具体地，本发明涉及编码能够改变种子储存含量，特别是油，脂质和脂肪酸代谢调节蛋白的多肽的核酸序列，以及这些序列在转基因植物中的用途。特别地，本发明涉及在植物和种子中操作种子储存化合物的方法。本发明还涉及使用这些新型植物多肽刺激植物生长和/或增加种子储存化合物的产量和/或组成的方法。

9. 发明申请

WO2008043849A3 PLANTS WITH INCREASED YIELD 审中-公开
标题翻译：植物增加
公开(公告)号：WO2008043849A3
公开(公告)日：2008-09-04
申请号：PCT/EP2007060912
申请日：2007-10-12
申请人： BASF PLANT SCIENCE GMBH , MAX PLANCK INST FUER MOLEKULAR , ZANK THORSTEN , OSWALD OLIVER , BAUER JOERG , ZRENNER RITA MARIA , KOSLOWSKY SILKE
发明人： ZANK THORSTEN , OSWALD OLIVER , BAUER JOERG , ZRENNER RITA MARIA , KOSLOWSKY SILKE
IPC分类号： C12N15/82 , A01H5/10 , C12N9/12
CPC分类号： C12N15/8247 , C12N9/1235 , C12N15/8261 , Y02A40/146
摘要： This invention relates generally to plant cells and/or plants with increased yield as compared to a corresponding non-transformed wild type plant cell by increasing or generating one or more activities of polypeptides associated with the intermediate phosphoribosylpyrophosphate (PRPP) in plants. In particular, this invention relates to plant cells and/or plants with increased yield as compared to a corresponding non- transformed wild type plant cell by increasing or generating one or more activities of phosphoribosyl pyrophosphate synthases (PRPP synthetase, PRS) The invention also deals with methods of producing and screening for and breeding such plant cells and/or plants.
摘要翻译：与相应的未转化的野生型植物细胞相比，通过增加或产生与植物中的中间磷酸核糖基焦磷酸（PRPP）相关的多肽的一种或多种活性，本发明一般涉及具有增加的产量的植物细胞和/或植物。特别地，本发明涉及通过增加或产生磷酸核糖焦磷酸合酶（PRPP合成酶，PRS）的一种或多种活性而与相应的未转化的野生型植物细胞相比具有增加的产量的植物细胞和/或植物。本发明还涉及使用生产和筛选和繁殖这种植物细胞和/或植物的方法。

10. 发明申请

WO2006125756A2 NUCLEIC ACID MOLECULES ENCODING ECHI-LIKE POLYPEPTIDES AND METHODS OF USE 审中-公开
标题翻译：编码类似多聚核苷酸的核酸分子及其使用方法
公开(公告)号：WO2006125756A2
公开(公告)日：2006-11-30
申请号：PCT/EP2006062471
申请日：2006-05-19
申请人： BASF PLANT SCIENCE GMBH , ZANK THORSTEN , OSWALD OLIVER
发明人： ZANK THORSTEN , OSWALD OLIVER
IPC分类号： C12N15/82 , A01H5/00 , C12N15/29 , C12N15/60 , C12N15/61
CPC分类号： C12N15/8247 , C07K14/415 , C12N9/88 , C12N9/90
摘要： Described herein are inventions in the field of genetic engineering of plants, including isolated nucleic acid molecules encoding putative peroxisomal enoyl CoA hydratase/isomerase (ECHI) to improve agronomic, horticultural, and quality traits. This invention relates generally to nucleic acid sequences encoding proteins that are related to the presence of seed storage compounds in plants. More specifically, the present invention relates to ECHI-like nucleic acid sequences encoding lipid metabolism proteins (LMP) and the use of these sequences in transgenic plants. In particular, the invention is directed to methods for manipulating fatty acid-related compounds and for increasing oil level and altering the fatty acid composition in plants and seeds. The invention further relates to methods of using these novel plant polypeptides to stimulate plant growth and/or to increase yield and/or composition of seed storage compounds..
摘要翻译：本文描述了植物基因工程领域的发明，包括编码推定的过氧化物酶体烯酰辅酶A水合酶/异构酶（ECHI）的分离核酸分子，以改善农艺，园艺和品质性状。本发明一般涉及编码与种子储存化合物在植物中的存在有关的蛋白质的核酸序列。更具体地，本发明涉及编码脂质代谢蛋白（LMP）的ECHI样核酸序列和这些序列在转基因植物中的用途。特别地，本发明涉及用于操作脂肪酸相关化合物和增加油含量和改变植物和种子中的脂肪酸组成的方法。本发明还涉及使用这些新型植物多肽刺激植物生长和/或增加种子储存化合物的产量和/或组成的方法。

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