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    • 4. 发明申请
    • SUBSTITUTED AZOLIN-2-YL-AMINO COMPOUNDS
    • 取代的AZOLIN-2-YL-AMINO化合物
    • WO2008017649A1
    • 2008-02-14
    • PCT/EP2007/058109
    • 2007-08-06
    • BASF AKTIENGESELLSCHAFTKORADIN, ChristopherKORDES, MarkusLE VEZOUET, RonanCULBERTSON, Deborah L.ANSPAUGH, Douglas D.
    • KORADIN, ChristopherKORDES, MarkusLE VEZOUET, RonanCULBERTSON, Deborah L.ANSPAUGH, Douglas D.
    • C07D277/18C07D417/12A01N43/00
    • C07D417/12A01N43/50A01N43/76A01N43/78C07D277/18
    • The present invention relates to azolin-2-yl-amino compounds of formulae (I. a) and (l.b) and their salts which are useful for combating animal pest, in particular arthropod and nematodes. The present invention also relates to a method for combating such pests and for protecting crops against infestation or infection by such pests. Furthermore, the present invention relates to veterinary compositions for combating animal pests. Formula (I.a), formula (I.b) wherein n is 0 to 4; X is S, O or NR 5 ; A is -C(R 6a )(R 6b )-, O, NR 7 , S, S(O) or S(O) 2 ; B is a bond Or CH 2 ; R 1 is H, CN, C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, C 1 -C 6 -alkylcarbonyl, C 3 -C 6 -cycloalkyl, phenyl, benzyl, etc.; R 2a , R 2b are H, CN, C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, C 1 -C 6 -alkylcarbonyl, C 1 -C 6 -alkoxycarbonyl, (C 1 -C 6 -alkyl)thiocarbonyl, C(O)NR a R b , C(S)NR a R b , (SO 2 )NR a R b , phenyl, benzyl, 5 or 6 membered heterocyclic ring etc.; or R 1 together with R 2a is C 3 -C 5 -alkandiyl; or R 1 together with R 2b are C(O); R 3a , R 3b , R 3c , R 3d are H, halogen, CN, C 1 -C 6 -alkyl, C 1 -C 6 -alkylamino, C 3 -C 6 -cycloalkyl, phenyl, benzyl, etc.; R 4a , R 4b are H, halogen, C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, phenyl, benzyl, 5 or 6 membered hetaryl; or R 4a together with R 4b may also be =0, =NR C or =CR d R e ; or R 2a together with R 4a may form a bridging bivalent radical.
    • 本发明涉及用于对抗动物害虫,特别是节肢动物和线虫的式(Ⅰa)和(Ⅰ.B)的吡咯烷-2-基氨基化合物及其盐。 本发明还涉及一种防治这种害虫并防止作物抵抗这种害虫侵染或感染的方法。 此外,本发明涉及用于对抗动物害虫的兽用组合物。 式(Ⅰa),式(Ⅰb)其中n为0-4; X是S,O或NR 5; A是-C(R 6a)(R 6b) - ,O,NR 7,S,S(O)或S(O ) 2 ; B是键或CH 2 2; R 1是H,CN,C 1 -C 6 - 烷基,C 2 -C 3 - C 1 -C 6 - 亚烷基,C 1 -C 6 - 烷基羰基,C 3 -C 6 - 环烷基,苯基,苄基等; R 2a,R 2b是H,CN,C 1 -C 6 - 烷基,C 1 -C 6烷基, C 1 -C 6亚烷基,C 1 -C 6 - 烷基羰基,C 1 -C 6 - 烷基羰基,C 1 -C 6 - C 6 -C 6 - 烷氧基羰基,(C 1 -C 6 - 烷基)硫代羰基,C(O)NR a C C(S)NR a R b,(SO 2)NR a, 苯基,苄基,5或6元杂环等; 或R 1与R 2a一起为C 3 -C 5 - 亚烷基; 或R 1和R 2b一起是C(O); R 3a,R 3b,R 3c,R 3d是H,卤素,CN,C C 1 -C 6 - 烷基,C 1 -C 6 - 烷基氨基,C 3 - C 6 -C 6 - 环烷基,苯基,苄基等; R 4a,R 4b是H,卤素,C 1 -C 6 - 烷基,C 1 -C 4烷基, C 2 -C 6 - 烯基,苯基,苄基,5或6元杂芳基; 或R 4a与R 4b一起也可以是= 0,= NR C或= CR D, SUP>电子; 或R 2a与R 4a一起可以形成桥连二价基团。
    • 9. 发明申请
    • 1-(AZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS
    • 1-(AZOLIN-2-YL)氨基-1,2-二苯醚化合物,用于组合动物饲料
    • WO2009004032A1
    • 2009-01-08
    • PCT/EP2008/058517
    • 2008-07-02
    • BASF SEKORDES, MarkusKORADIN, ChristopherLE VEZOUET, RonanBAUMANN, ErnstCULBERTSON, Deborah L.ANSPAUGH, Douglas D.OLOUMI-SADEGHI, HassanEBUENGA, Cecile
    • KORDES, MarkusKORADIN, ChristopherLE VEZOUET, RonanBAUMANN, ErnstCULBERTSON, Deborah L.ANSPAUGH, Douglas D.OLOUMI-SADEGHI, HassanEBUENGA, Cecile
    • C07D233/48C07D263/28C07D277/18C07D417/12C07D417/06A01N43/50A01N43/76A01N43/78
    • C07D263/28A01N43/50A01N43/76A01N43/78A01N47/12A01N47/16C07D233/48C07D277/18C07D417/06C07D417/12
    • The present invention relates to 1-(azolin-2-yl)amino-1,2-diphenylethane compounds of the formula I and to their salts which are useful for combating animal pests. The invention also relates to a method for controlling animal pests by using these compounds, to seed and to an agricultural and veterinary composition comprising said compounds, wherein A is a radical of formulae A.1 or A.2 wherein # denotes the bond to the remaining compound of formula I, X is selected from O, S and NR x , R 1 is selected from the group consisting of -OR A , -NR B1 R B2 , -C(=O)-R C , -C(=O)-OR D , -C(=O)-SR E , -C(=O)-NR B1 R B2' , -C(=S)-R C' , -C(=S)-OR D' , -C(=S)-SR E' , -C(=S)-NR B1 R B2 , -C(=NR 1a )-R C' , -C(=NR 1b )-OR D' , -C(=NR 1c )-SR E' , -C(=NR 1d )-NR B1 R B2 , -S(=O)-R F , -S(=O) 2 -R G , -S(=O) 2 -NR B1 R B2' , -P(=O)R H1 R H2 , -P(=S)R H1 R H2 , -B-C(=O)-R I , -B-O-C(=O)-R I , -B-S-C(=O)-R I , -B-N(R J )-C(=O)-R K , -B-C(=S)-R K , -B-O-C(=S)-R K , -B-S-C(=S)-R K , -B-N(R J )-C(=S)-R K , C 1 -C 8 -alkenyl, C 1 -C 8 -alkynyl, C 3 -C 8 -cycloalkyl, which is unsubstituted or may carry 1 to 4 substituents R 1e , naphthyl, which is unsubstituted or may carry 1 to 4 substituents R 1f , a saturated or partially unsaturated heterocycle, which is unsubstituted or may carry 1 to 4 substituents R 1g , hetaryl, which is unsubstituted or may carry 1 to 4 substituents R 1h , and C 1 -C 6 -alkyl, which carries a radical selected from the group consisting of -NR 1i R 1j , C 1 -C 4 -alkoxycarbonyl, C 3 -C 8 -cycloalkyl, aryl, aryloxy, arylthio, heterocyclyl, heterocyclyloxy and heterocyclylthio, R 2 , R 3 , R 4 , R 5 , R 6 and R 7 are each independently hydrogen, halogen, OH, SH, NH 2 , SO 3 H, COOH, cyano, nitro, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -alkylamino etc.
    • 本发明涉及式I的1-(吡唑-2-基)氨基-1,2-二苯基乙烷化合物及其盐,其可用于防治动物害虫。 本发明还涉及通过使用这些化合物,种子和包含所述化合物的农业和兽医组合物来控制动物害虫的方法,其中A是式A.1或A.2的基团,其中#表示与 剩余的式I化合物,X选自O,S和NR x,R1选自-ORA,-NRB1RB2,-C(= O)-RC,-C(= O)-OR,-C (= O)-SRE,-C(= O)-NRB1RB2',-C(= S)-RC',-C(= S)-OR',-C(= S)-SRE' =(NR1c)-SR',-C(= NR1d)-NRB1RB2,-S(= O) )-RF,-S(= O)2 -RG,-S(= O)2 -NRB 1 R B 2',-P(= O)RH1RH 2,-P(= S)RH1RH 2,-BC(= O) -BOC(= O)-RI,-BSC(= O)-RI,-BN(RJ)-C(= O)-RK,-BC(= S)-RK,-BOC(= S)-RK, -BSC(= S)-RK,-BN(RJ)-C(= S)-RK,C1-C8-烯基,C1-C8-炔基,C3-C8-环烷基,其未被取代或可携带1至4 取代基R 1e,萘基,其是未取代的或可以携带1至4个取代基R 1f,饱和或部分不饱和的杂环,其为未制备的 或可以携带1至4个未取代的或可以携带1至4个取代基R 1h的取代基R 1g,杂芳基,其中C 1 -C 6 - 烷基带有选自以下的基团:-NR 1 1 R 1,C 1 -C 4 - 烷氧基羰基, C 3 -C 8 - 环烷基,芳基,芳氧基,芳硫基,杂环基,杂环基氧基和杂环硫基,R 2,R 3,R 4,R 5,R 6和R 7各自独立地为氢,卤素,OH,SH,NH 2,SO 3 H,COOH,氰基,硝基, C 1 -C 6 - 烷基,C 1 -C 6 - 烷氧基,C 1 -C 6烷基氨基等