基本信息:
- 专利标题: CANCER BIOMARKERS AND USES THEREOF
- 专利标题(中):癌症生物标志物及其用途
- 申请号:PCT/US2010/026439 申请日:2010-03-05
- 公开(公告)号:WO2011031344A1 公开(公告)日:2011-03-17
- 发明人: GOLD, Larry , BRODY, Edward N. , OSTROFF, Rachel M. , ZICHI, Dominic , STEWART, Alex A.E. , MEHAN, Michael , MESSENBAUGH, Mark , SCHWARTZ, Randee S. , WALKER, Jeffery , WILLIAMS, Stephen Alaric , NIKRAD, Malti
- 申请人: SOMALOGIC, INC. , GOLD, Larry , BRODY, Edward N. , OSTROFF, Rachel M. , ZICHI, Dominic , STEWART, Alex A.E. , MEHAN, Michael , MESSENBAUGH, Mark , SCHWARTZ, Randee S. , WALKER, Jeffery , WILLIAMS, Stephen Alaric , NIKRAD, Malti
- 申请人地址: 2945 Wilderness Place Boulder, Colorado 80301 US
- 专利权人: SOMALOGIC, INC.,GOLD, Larry,BRODY, Edward N.,OSTROFF, Rachel M.,ZICHI, Dominic,STEWART, Alex A.E.,MEHAN, Michael,MESSENBAUGH, Mark,SCHWARTZ, Randee S.,WALKER, Jeffery,WILLIAMS, Stephen Alaric,NIKRAD, Malti
- 当前专利权人: SOMALOGIC, INC.,GOLD, Larry,BRODY, Edward N.,OSTROFF, Rachel M.,ZICHI, Dominic,STEWART, Alex A.E.,MEHAN, Michael,MESSENBAUGH, Mark,SCHWARTZ, Randee S.,WALKER, Jeffery,WILLIAMS, Stephen Alaric,NIKRAD, Malti
- 当前专利权人地址: 2945 Wilderness Place Boulder, Colorado 80301 US
- 代理机构: SWANSON & BRATSCHUN, L.L.C. et al.
- 优先权: US12/556,480 20090909
- 主分类号: A61B5/00
- IPC分类号: A61B5/00 ; G01N33/48 ; G01N33/574
摘要:
The present disclosure includes biomarkers, methods, devices, reagents, systems, and kits for the detection and diagnosis of cancer. In one aspect, the disclosure provides biomarkers that can be used alone or in various combinations to diagnose cancer. In another aspect, methods are provided for diagnosing cancer in an individual, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 47, wherein the individual is classified as having cancer, or the likelihood of the individual having cancer is determined, based on the at least one biomarker value.
摘要(中):
本公开包括用于癌症的检测和诊断的生物标志物,方法,装置,试剂,系统和试剂盒。 一方面,本公开提供可以单独使用或以各种组合使用以诊断癌症的生物标志物。 在另一方面,提供了用于诊断个体癌症的方法,其中所述方法包括在来自个体的生物样品中检测至少一个对应于选自表47中提供的生物标志物组的生物标志物的生物标记值, 其中所述个体基于所述至少一种生物标志物值被分类为具有癌症或确定个体患有癌症的可能性。
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61B | 诊断;外科;鉴定 |
------A61B5/00 | 用于诊断目的的测量;人的辨识 |