基本信息:
- 专利标题: NOVEL PEPTIDE AND ITS PREPARATION
- 申请号:JP1424682 申请日:1982-01-29
- 公开(公告)号:JPS57145845A 公开(公告)日:1982-09-09
- 发明人: HASHIMOTO SHINJI , KITAURA YOSHIHIKO , NAKAGUCHI OSAMU , HENMI KEIJI , TAKENO SHIYUUICHI , OKADA TATSU , YONISHI SATOSHI
- 申请人: FUJISAWA PHARMACEUTICAL CO
- 专利权人: FUJISAWA PHARMACEUTICAL CO
- 当前专利权人: FUJISAWA PHARMACEUTICAL CO
- 优先权: GB8102706 1981-01-29; GB8109576 1981-03-26
- 主分类号: A61K31/16
- IPC分类号: A61K31/16 ; A61K38/00 ; A61P31/04 ; A61P37/04 ; C07C67/00 ; C07C231/00 ; C07C231/02 ; C07K1/02 ; C07K1/113 ; C07K5/02
摘要:
NEW MATERIAL:To peptide compound of formualaI(R is heptanoyl, R is benzyl, R is 1-carboxylethylamino, R is carboxy or methoxycarbonyl, n is 0; or R is stearoyl, R is benzyl, R is 1-ethoxycarbonylethylamino, R is ethoxycarbonyl, n is 1; etc.) and its salt. EXAMPLE:Stearoyl-L-alanyl-gamma-D-glutamyl(alpha-OH)-(L)-meso alpha, epsilon-diaminopimelyl-(D)- O-methyl-(L)-D-alanyl 0-methyl. USE:Remedy for infectious diseases. Useful for the remedy of infectious diseases caused by Gram-positive bacteria, Gram-negative bacteria, molds, etc. PROCESS:The compound of formulaIa is prepared by reacting the compound of formula II or its salt with the compound of formula III (Ra is carboxy or methoxycarbonyl) or its salt.
公开/授权文献:
- JPH068312B2 公开/授权日:1994-02-02
信息查询:
EspacenetIPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K31/00 | 含有机有效成分的医药配制品 |
--------A61K31/16 | .酰胺,例如异羟肟酸 |