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1. 发明专利

JP2003146906A COMBINED THERAPEUTIC AGENT FOR PROPHYLAXIS OR THERAPY OF INFECTIOUS DISEASE WITH GRAM-POSITIVE BACTERIUM 失效
公开(公告)号：JP2003146906A
公开(公告)日：2003-05-21
申请号：JP8078699
申请日：1999-03-25
申请人： FUJISAWA PHARMACEUTICAL CO
发明人： YOKOTA YOSHIKO
IPC分类号： A61K31/00 , A61K31/43 , A61K31/431 , A61K31/535 , A61K31/5375 , A61K31/5383 , A61K31/545 , A61K31/546 , A61K31/65 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/7036 , A61K31/7042 , A61K31/7048 , A61K45/06 , A61P31/00 , A61P31/04
摘要： PROBLEM TO BE SOLVED: To provide a new combined therapeutic agent for therapy or prophylaxis of infectious diseases with Gram-positive bacteria. SOLUTION: This combined therapeutic agent for the prophylaxis or therapy of the infectious diseases with the Gram-positive bacteria is used by administering at least one kind of β-lactam-based antibiotic having antistaphylococcus activity with at least one kind of antibiotic selected from a tetracycline antibiotic, a quinolone antibiotic, an aminoglycoside antibiotic and a macrolide antibiotic simultaneously or separately at a time interval.

2. 发明专利

JP2002294307A METALLIC COLLOIDAL SOLUTION, PRODUCTION METHOD THEREFOR, ELECTRICALLY CONDUCTIVE INK AND ELECTRICALLY CONDUCTIVE FILM 失效
公开(公告)号：JP2002294307A
公开(公告)日：2002-10-09
申请号：JP2001097002
申请日：2001-03-29
申请人： FUJISAWA PHARMACEUTICAL CO , BANDO CHEMICAL IND
发明人： YOSHIYASU TAKASHI , KAKIUCHI TOSHIHITO , TAKEI MASASHI , KAMATA MINORU , TONOMURA TAKUYA
IPC分类号： B01J13/00 , B22F9/00 , C09D11/00 , C09D11/52 , H01B1/22 , H01B13/00
摘要： PROBLEM TO BE SOLVED: To provide a metallic colloidal solution which is produced by a simple production method and has high dispersibility, and exhibits high electric conductivity. SOLUTION: The metallic colloidal solution contains at least one kind of compound selected from the groups consisting of polyene polycarboxylic acid, the derivative thereof in a carboxylic group, and the salts thereof. Preferably, the above polyene polycarboxylic acid is a compound expressed by the formula (1) [in the formula, (n) is an integer of 0 to 5; and (m) is an integer of 1 or 2; wherein, (m) is 1 when (n) is zero]. In the method for producing the metallic colloidal solution by reducing metallic salt with a reducing agent, the reducing agent consists of tannic acid.

3. 发明专利

JP2002284658A THERAPEUTIC AGENT FOR ODOR OF THE ARMPIT 失效
公开(公告)号：JP2002284658A
公开(公告)日：2002-10-03
申请号：JP2001095288
申请日：2001-03-29
申请人： FUJISAWA PHARMACEUTICAL CO
发明人： KAGAWA KAZUHIKO , TSUDA YOJI , MATSUDA TERUKO , YABUTA TSUGIO , YOSHIDA HISAMI
IPC分类号： A61K8/00 , A61K31/355 , A61K31/375 , A61P17/00 , A61Q15/00 , A61K7/32
摘要： PROBLEM TO BE SOLVED: To provide a therapeutic agent for the odor of the armpit which has a high preventive effect to the odor of the armpit and has no problem concerning safety. SOLUTION: The therapeutic agent for the odor of the armpit contains a vitamin E and/or a vitamin C as the active ingredients.

4. 发明专利

JP2002161051A THERAPEUTIC AGENT FOR CEREBRAL ISCHEMIC DISEASE OR THE LIKE 失效
公开(公告)号：JP2002161051A
公开(公告)日：2002-06-04
申请号：JP34319296
申请日：1996-12-24
申请人： FUJISAWA PHARMACEUTICAL CO
发明人： KUSHIMA HIROSHI
IPC分类号： A61K38/55 , A61K38/03 , A61K45/00 , A61P9/00 , A61P25/00 , A61P25/28 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To obtain a therapeutic agent for cerebral ischemic diseases, etc., comprising a substance having human leukocyte elastase inhibitory activity as an active ingredient. SOLUTION: This therapeutic agent for the cerebral ischemic diseases, etc., comprises a substance having a human leukocyte elastase inhibitory activity as an active ingredient.

5. 发明专利

JP2002088075A AMINATED FULLERENE DERIVATIVE 失效
公开(公告)号：JP2002088075A
公开(公告)日：2002-03-27
申请号：JP2000272114
申请日：2000-09-07
申请人： NAKAMURA EIICHI , FUJISAWA PHARMACEUTICAL CO
发明人： NAKAMURA EIICHI , ISOBE HIROYUKI , TOMITA NAOTERU
IPC分类号： C12N15/09 , A61K31/713 , A61K48/00 , A61P43/00 , C07C215/44 , C07D295/08 , C07D303/36 , C07D493/10
摘要： PROBLEM TO BE SOLVED: To provide a new nucleic acid-condensing reagent useful for transfection. SOLUTION: This new reagent is an aminated fullerene derivative of the formula [wherein, R1 and R2 are each a (substituted) hydrocarbon group and may form a (substituted) nitrogen-containing heterocyclic ring together with the nitrogen atom to which R1 and R2 are bound].

6. 发明专利

JP2002065856A CONCENTRATED OXYGEN FEEDER 失效
公开(公告)号：JP2002065856A
公开(公告)日：2002-03-05
申请号：JP2000258480
申请日：2000-08-29
申请人： FUJISAWA PHARMACEUTICAL CO
发明人： HIGUCHI MAMORU
IPC分类号： A61M16/10
摘要： PROBLEM TO BE SOLVED: To provide a concentrated oxygen feeder capable of immediately feeding the optimum quantity of oxygen even when the breathing condition of a user is changed when breathing concentrated oxygen. SOLUTION: An operation unit 6 of a control device 5 operates the oxygen supply necessary for the user from the pulse count and/or the degree of saturation of the arterial blood oxygen of the user measured by a measuring unit 8 for measuring the pulse count and/or the degree of saturation of the arterial blood oxygen of a user, and an opening/closing time of an automatic control valve is operated based on the result of operation. A control unit 7 of the control device controls the opening/closing of the automatic control valve 4 provided on a concentrated oxygen feed pipe 3 for connecting a concentrated oxygen feeding means 1 to a concentrated oxygen intake means 2 based on the result of operation.

7. 发明专利

JP2001334102A METHOD FOR DESORBING SOLVENT FROM CLATHRATE CRYSTAL 失效
公开(公告)号：JP2001334102A
公开(公告)日：2001-12-04
申请号：JP2000160591
申请日：2000-05-30
申请人： FUJISAWA PHARMACEUTICAL CO
发明人： KUBOTA ARIKATSU , YASUDA HIRONOBU , ZANKA ATSUHIKO , GOSHIMA SHUNSUKE , HIRABAYASHI SATOSHI
IPC分类号： C07D401/12 , B01D12/00
摘要： PROBLEM TO BE SOLVED: To remove solvent, which is contained in a clathrate crystal and is hardly desorbed, in a short time without causing transition of the crystal. SOLUTION: The solvent contained in the clathrate crystal is displaced with solvent to be more easily desorbed, which is then desorbed from the clathrate crystal.

8. 发明专利

JP2001259302A APPARATUS FOR SEPARATING CONCENTRATED LIQUID IN ICICLE 失效
公开(公告)号：JP2001259302A
公开(公告)日：2001-09-25
申请号：JP2000077747
申请日：2000-03-21
申请人： FUJISAWA PHARMACEUTICAL CO , Y S DENSHI KOGYO KK
发明人： YAMAZAKI HIROSHI , SUGITA YOSHIO
IPC分类号： B01D9/04
摘要： PROBLEM TO BE SOLVED: To simplify separation operation of a concentrated liquid by making it possible to continuously carry out the separation operation. SOLUTION: Two columns 43 are so disposed as to separate a concentrated liquid from an icicle growing upward from an inner cylinder where the icicle is growing. Each column 43 is separately moved from an upper installation part which receives an icicle growing upward in the inner cylinder immediately above the inner cylinder and a side installation part parted from the immediately above part toward a side. Cold water is supplied to each column 43 and the concentrated liquid is discharged out the icicle in the column 43. Further, a cutter to cut the icicle in a prescribed length is installed in each column 43 in a manner the cutter can be stored. A cold water jacket 51 for cooling each column 43 is installed and on the other hand, an induction heating coil 61 for heating each column 43 is also installed.

9. 发明专利

JP2001220375A NEW AMIDE COMPOUND 失效
公开(公告)号：JP2001220375A
公开(公告)日：2001-08-14
申请号：JP2000359201
申请日：2000-11-27
申请人： FUJISAWA PHARMACEUTICAL CO
发明人： ITO KIYOTAKA , GLEN W SPEARS , YAMADA AKIRA , TOMIJIMA MASANORI , KATO MASAYUKI
IPC分类号： C07D213/36 , A61K31/167 , A61K31/335 , A61K31/403 , A61K31/404 , A61K31/4402 , A61P25/00 , A61P25/06 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P43/00 , C07C257/18 , C07D209/42 , C07D209/88 , C07D209/94 , C07D313/08
摘要： PROBLEM TO BE SOLVED: To obtain a new amide compound or its salt, in detail, a new amide compound having a pharmacological activity such as 5-hydroxytryptamine (5-HT) antagonism, etc., or its salt. SOLUTION: This compound is represented by general formula (I) R1-A- X-NHCO-R2 (I) (R1 is an aryl group which may contain a substituent group or a heterocyclic group which may contain a substituent group; R2 is a condensed phenyl group which may contain a substituent group, a phenyl group which may contain a substituent group or an indolin-1-yl group substituted with a lower alkylthio group and a trihalo (lower) alkyl group; A is a group of formula (II) or group (III) (R3, R4 and R5 are each a hydrogen atom or a lower alkyl group); X is a phenylene group or a lower alkylene group) or its salt.

10. 发明专利

JP2001029713A APPARATUS FOR TAKEOUT OF INTER-PARTICLE SUBSTANCE FROM SOLID PARTICLE AGGREGATE 失效
公开(公告)号：JP2001029713A
公开(公告)日：2001-02-06
申请号：JP20566599
申请日：1999-07-21
申请人： SHIN NIPPON AIR TECH CO LTD , Y S DENSHI KOGYO KK , FUJISAWA PHARMACEUTICAL CO , ASAHI GLASS ENGINEERING CO LTD
发明人： MIURA KUNIO , MIYATA SHUN , IGUCHI YASUO , TERAI HIROTAKA , KURODA HISANORI , SUGITA YOSHIO
IPC分类号： B01D9/04 , B01D35/147
摘要： PROBLEM TO BE SOLVED: To efficiently take out inter-particle substance of a solid particle aggregate. SOLUTION: A takeout apparatus 1 comprises a cylindrical filling container 2 arranged vertically, a cooling pipeline 3 buried in a wall part so that almost entire wall part 2W can be cooled, a filter 4 which blocks an outlet side of the filling container 2, not allowing ice particle to pass through, but allowing takeout water and takeout substance to pass through, and a collecting pipeline 5 for collecting the takeout water and the takeout substance which pass through the filter 4. The takeout water W passing through a clearance S between an inner face 2n of the container and an outer face 10s of an ice particle aggregate through a container wall part 2W is cooled by distributing cold water in the cooling pipeline 3 always or at proper times during takeout, and passing resistance of the takeout water W in the clearance S is allowed to approach at least the passing resistance of the takeout water between particles of the ice particle aggregate 10. Thereby, the passing of the takeout water inside and outside the ice particle aggregate 10 is uniformized, and efficient takeout can be carried out.

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