发明专利
JPH0873500A MONOCLONAL ANTIBODY FOR EPSILON-(GAMMA-GLUTAMYL)LYSINE CROSS-LINKED SITE AND METHOD FOR IMMUNOASSAY
失效
基本信息:
- 专利标题： MONOCLONAL ANTIBODY FOR EPSILON-(GAMMA-GLUTAMYL)LYSINE CROSS-LINKED SITE AND METHOD FOR IMMUNOASSAY
- 申请号：JP20851394 申请日：1994-09-01
- 公开(公告)号：JPH0873500A 公开(公告)日：1996-03-19
- 发明人： OOTSUKA TOMOKO , SEGURO KATSUYA , MOTOKI MASAO , IKURA KOJI , SASAKI RYUZO
- 申请人： AJINOMOTO KK
- 专利权人： AJINOMOTO KK
- 当前专利权人： AJINOMOTO KK
- 优先权： JP20851394 1994-09-01
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C07K16/00 ; C07K16/04 ; C07K19/00 ; C12N15/02 ; C12P21/08 ; C12R1/91 ; G01N33/577
摘要：
PURPOSE: To provide both a means for simply detecting and determining only an ε-(γ-glutamyl)lysine cross-linked site with a high sensitivity in a short time without being influenced by a difference in kind of proteins as compared with a conventional method and a method for detecting and determining the ε-(γ- glutamyl)lysine cross-linked site without breakage. CONSTITUTION: This method for determining an ε-(γ-glutamyl)lysine cross-linked site according to an immunoassay using a monoclonal antibody having a high affinity for the ε-(γ-glutamyl)lysine cross-linked site. Thereby, the distribution of the ε-(γ-glutamyl)lysine cross-linked site is measured by using the anti-ε-(γ- glutamyl)lysine cross-linked site monoclonal antibody.