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1. 发明申请

WO2023081928A1 THERAPEUTIC METHOD FOR THE EYE USING ULTRASOUND 审中-公开
公开(公告)号：WO2023081928A1
公开(公告)日：2023-05-11
申请号：PCT/US2022/079491
申请日：2022-11-08
申请人： ARCSCAN, INC.
发明人： GIPHART, Johan E. , LEVIEN, Andrew K. , WATSON, John David
IPC分类号： A61B8/10 , A61B3/117 , A61N7/00 , A61F9/007
摘要： The present disclosure relates to ultrasound imaging and treatment of an eye and in particular directed to an apparatus and method for reducing intraocular pressure by 1) ablating the ciliary process which is the structure responsible for production of aqueous humor and 2) by vibrating the trabecular mesh to stimulate better drainage of fluid through the trabecular mesh and out of the eye. The present disclosure describes an apparatus and method for forming a high precision image of the eye wherein the resolution is sufficient to image, for example, ciliary body and region around the trabecular mesh. The present disclosure further discloses an imaging transducer and an irradiating therapeutic transducer that can be mounted such that they are movable between a plurality of positions.

2. 发明申请

WO2023003136A1 딥러닝을 이용한 백내장 진단방법 및 시스템 审中-公开
公开(公告)号：WO2023003136A1
公开(公告)日：2023-01-26
申请号：PCT/KR2022/005134
申请日：2022-04-08
申请人： 사회복지법인 삼성생명공익재단
发明人： 임동희 , 손기영 , 신은혜 , 고종우
IPC分类号： A61B3/117 , A61B3/00 , G16H50/20 , G16H50/30 , G16H30/40 , A61B3/135 , G06N3/08 , G06N3/04
摘要： 본 발명은 딥러닝을 이용한 백내장 진단방법 및 시스템에 관한 것으로, 더욱 상게하게는 딥러닝을 이용하여 세극등 현미경 검사결과 이미지 및 역반사조명 검사결과 이미지로부터 백내장 진행정도를 예측하고, 이를 기준으로 백내장의 심각성을 평가하여 치료계획을 수립 및 제공하는 딥러닝을 이용한 백내장 진단방법 및 시스템에 관한 것이다. 본 발명의 일 실시예에 따른 딥러닝을 이용한 백내장 진단방법은, 입력부가 세극등 현미경(Slit lamp) 검사결과 이미지 및 피검사자의 건강검진 결과를 수신하는 입력단계, 백내장 진단부가 상기 세극등 현미경 검사결과 이미지를 딥러닝 예측모델에 입력하여 수정체 핵의 백내장 진행 정도를 예측하고, 상기 피검사자가 백내장인지 여부를 판별하는 백내장 진단단계, 심각성 평가부가 상기 수정체 핵의 백내장 진행 정도를 기준으로 상기 피검사자의 백내장 심각성을 평가하는 백내장 심각성 평가단계 및 치료단계 판단부가 상기 백내장 심각성 또는 건강검진 결과를 이용하여 상기 피검사자에게 필요한 백내장 치료단계를 판단하여 제공하는 치료계획 제공단계를 포함 할 수 있다.

3. 发明申请

WO2021252621A1 ENHANCED GONIOMETER 审中-公开
公开(公告)号：WO2021252621A1
公开(公告)日：2021-12-16
申请号：PCT/US2021/036607
申请日：2021-06-09
申请人： PMOTION, INC.
发明人： PYNE, Keith
IPC分类号： A61B3/117 , A61B5/103 , A61B5/11 , A61B5/1071 , A61B5/1121 , A61B5/6898 , A61B5/742 , A61B5/7475
摘要： Methods, systems, and apparatus, including computer programs encoded on computer-storage media, for an enhanced goniometer. In some implementations, a method includes obtaining a sequence of measurements to be measured based on one or more data points of an examination; receiving input from a user initiating a measurement; receiving raw data from a measuring component; processing the raw data to exclude measurements corresponding to one or more axes; generating a measurement result based on the processed raw data; and providing the measurement result for output.

4. 发明申请

WO2021126372A1 SYSTEM AND METHOD FOR LOCATING A STRUCTURE OF OCULAR TISSUE FOR GLAUCOMA SURGERY BASED ON SECOND HARMONIC LIGHT 审中-公开
公开(公告)号：WO2021126372A1
公开(公告)日：2021-06-24
申请号：PCT/US2020/057573
申请日：2020-10-27
申请人： VIALASE, INC.
发明人： JUHASZ, Tibor , MIKULA, Eric, R.
IPC分类号： A61F9/008 , A61B3/117 , A61F2009/00851 , A61F2009/00868 , A61F2009/0088 , A61F2009/00891 , A61F9/00825
摘要： A structure in an irido-comeal angle of an eye is located by directing a laser beam toward the irido-comeal angle of the eye, and advancing a focus of the laser beam to a location in the irido-corneal angle, which location is at or near the target structure. The focus is determined to be at or near the structure based on changes in an intensity of a spot of second harmonic light generated by an encounter between the focus and tissue.

5. 发明申请

WO2019103631A1 PORTABLE GONIOSCOPE 审中-公开
公开(公告)号：WO2019103631A1
公开(公告)日：2019-05-31
申请号：PCT/PH2018/000015
申请日：2018-11-23
申请人： REMO, Jocelyn Therese M. , TAN, Jaesser T.
发明人： REMO, Jocelyn Therese M. , TAN, Jaesser T.
IPC分类号： A61B3/117
摘要： The present invention discloses a portable gonioscopy system comprising a portable gonioscope, said portable gonioscope further comprising a goniolens assembly, a body further comprising a light source with a filtering means, image capturing means such as a microscope lens and a viewing lens or device capable of recording images; and said portable gonioscope being coupled to a viewing means and a recording means. This portable gonioscope provides an alternative device to slit lamp gonioscope, which allows ophthalmological examination specially in the iridocorneal angle of the eye, anywhere possible outside of a hospital, thereby bringing convenience for field works and medical missions in remote areas.

6. 发明申请

WO2019012881A1 画像処理装置、眼科用観察装置及び眼科用観察システム审中-公开
公开(公告)号：WO2019012881A1
公开(公告)日：2019-01-17
申请号：PCT/JP2018/022052
申请日：2018-06-08
申请人：ソニー株式会社
发明人：榎　潤一郎 , 坂口　竜己 , 大月　知之 , 相馬　芳男
IPC分类号： A61B3/117
摘要：【課題】眼の観察に適した画像処理装置、眼科用観察装置及び眼科用観察システムを提供すること。【解決手段】本技術に係る画像処理装置は、画像生成部を具備する。上記画像生成部は、眼に装着された前置レンズを介して撮像された撮像画像において、上記前置レンズによって像が反転している画像領域である反転領域を反転させ、表示画像を生成する。

7. 发明申请

WO2018232397A1 METHODS AND SYSTEMS FOR OCT GUIDED GLAUCOMA SURGERY 审中-公开
公开(公告)号：WO2018232397A1
公开(公告)日：2018-12-20
申请号：PCT/US2018/038072
申请日：2018-06-18
申请人： BERLIN, Michael S.
发明人： BERLIN, Michael S.
IPC分类号： A61B3/117 , A61B3/13
摘要： Disclosed herein are systems and methods for aiding a surgeon to perform a surgical procedure on an eye. The surgical procedure includes inserting an elongate probe from an opening into the eye across an anterior chamber to a target tissue region comprising a trabecular meshwork and a Schlemm' s canal. Exemplary systems include an optical microscope for the surgeon to view the eye with a microscope image during the procedure; an optical coherence tomography (OCT) apparatus configured to perform an OCT scan of a target location in the target tissue region during the procedure; and an image processing apparatus configured to generate an augmented image by overlaying an OCT image of target location and a graphical visual element identifying the locations, wherein the graphical visual element is registered with the microscope image to aid the surgeon in advancing a distal end of the elongate probe to the target location.

8. 发明申请

WO2017191487A1 OVERLAY IMAGING FOR REGISTRATION OF A PATIENT EYE FOR LASER SURGERY 审中-公开
标题翻译：用于注册激光手术患者眼睛的覆盖成像
公开(公告)号：WO2017191487A1
公开(公告)日：2017-11-09
申请号：PCT/IB2016/052496
申请日：2016-05-02
申请人： NOVARTIS AG
发明人： ABRAHAM, Mario , WITTNEBEL, Michael , STEHR, Matthias
IPC分类号： A61B3/117
CPC分类号： A61B34/10 , A61B3/117 , A61B34/25 , A61B90/39 , A61B2034/105 , A61B2090/3937 , A61B2090/3983 , A61B2090/3995 , A61F9/008 , A61F2009/00878 , G06T3/60 , G06T7/337 , G06T2207/10024 , G06T2207/20221 , G06T2207/30041 , G06T2207/30204
摘要： Methods and systems for overlay imaging for registration of a patient eye for laser surgery include aligning and overlaying a surgical image of the limbus over a previously acquired diagnostic image of the limbus. The surgical image is displayed with a degree of transparency and enabled to rotate about the limbus center. Various types of colors, markers, contrast, and backgrounds may be used to generate a display for determining the alignment angle between the diagnostic image and the surgical image.
摘要翻译：用于配准用于激光手术的患者眼睛的覆盖成像的方法和系统包括将边缘的手术图像对准并覆盖在先前采集的角膜缘诊断图像上。手术图像以一定程度的透明度显示并能够围绕角膜缘中心旋转。可以使用各种类型的颜色，标记，对比度和背景来生成用于确定诊断图像和手术图像之间的对准角度的显示器。

9. 发明申请

WO2016154066A3 GONIOSCOPIC DEVICES 审中-公开
公开(公告)号：WO2016154066A3
公开(公告)日：2016-09-29
申请号：PCT/US2016/023296
申请日：2016-03-18
申请人： GLAUKOS CORPORATION
发明人： KALINA, Charles, Raymond , BURNS, Thomas, W. , CALCATERRA, Chris , COLLINS, Edward , MCCAULEY, Timothy , HAFFNER, David, S. , HENDERSON, Steven, M.
IPC分类号： A61B3/117
摘要： A gonioscopic attachment can attach to a gonioscope and can include atraumatic retention elements that are configured to engage an eye to retain the gonioscope relative to the eye. Tire gonioscopic attachment can be configured to position the gonioscope so that at least a portion of the concave distal surface of the gonioscopic optical element is spaced apart from the eye, and/or so that the curvature of the distal surface is angularly offset from the curvature of the eye. The gonioscope can include a fixation point configured to be visible to the subject when the gonioscope is positioned on the eye. In some embodiments, the retention elements can be incorporated directly into the gonioscope. A coupling mechanism can couple the gonioscope to a lid speculum. The gonioscope can include a light pipe, which can be configured to directly light into the eye.

10. 发明申请

WO2016131815A1 VORRICHTUNG UND VERFAHREN ZUR BESTIMMUNG MINDESTENS EINER MECHANISCHEN EIGENSCHAFT EINES UNTERSUCHUNGSOBJEKTS 审中-公开
标题翻译：设备和方法确定研究点中的至少一个机械属性
公开(公告)号：WO2016131815A1
公开(公告)日：2016-08-25
申请号：PCT/EP2016/053246
申请日：2016-02-16
申请人： UNIVERSITÄT ROSTOCK
发明人： STOLZ, Heinrich , REISS, Stephan , SPERLICH, Karsten , STACHS, Oliver , GUTHOFF, Rudolf
IPC分类号： A61B3/00 , A61B5/00 , A61B3/117 , G01S17/02
CPC分类号： A61B5/0097 , A61B3/117 , A61B8/10
摘要： Die Erfindung betrifft eine Vorrichtung und ein Verfahren zur Bestimmung mindestens einer mechanischen Eigenschaft eines Untersuchungsobjekts, wobei die Vorrichtung aufweist: eine erste Signalquelle zum Erzeugen eines ersten Signals mit einer ersten Frequenz, wobei das erste Signal in das Untersuchungsobjekt einkoppelbar ist, eine weitere Signalquelle zum Erzeugen eines weiteren Signals mit einer weiteren Frequenz, wobei die weitere Frequenz von der ersten Frequenz verschieden ist, wobei die weitere Frequenz veränderbar ist, wobei das weitere Signal derart in das Untersuchungsobjekt einkoppelbar ist, dass sich das erste und weitere Signal in zumindest einem Teilbereich des Untersuchungsobjekts überlagern, eine Einrichtung zur Erfassung einer Intensität eines gestreuten Anteils (6) des ersten Signals, wobei der gestreute Anteil (6) ein durch das weitere Signal gestreuter Anteil des ersten Signals ist.
摘要翻译：本发明涉及的装置和用于确定物体的至少一个机械特性的方法来进行检查，该装置包括：用于产生具有第一频率，其中所述第一信号是在检查耦合到对象，用于产生另外的信号源的第一信号的第一信号源进一步的信号到另外的频率，所述第一频率的多个频率是不同的，其它频率是可变的，其中所述进一步的信号可以以这样的方式，在检查对象被耦合，第一和另外的信号到所述物体的至少一部分要被检查重叠的装置，用于检测所述第一信号，其中，所述散射部分（6）是一个散射由第一信号的另外的信号部分的散射部分（6）的强度。

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