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    • 1. 发明申请
    • DEVICE FOR MONITORING HIFU TREATMENTS
    • WO2021130702A1
    • 2021-07-01
    • PCT/IB2020/062408
    • 2020-12-23
    • IMEDICALS SRL
    • CASCIARO, Sergio
    • A61N7/02A61B8/08G06T7/11A61B34/30A61B8/00A61B5/11A61B34/10A61B2034/104A61B2034/105A61B2034/2048A61B2034/2051A61B2090/067A61B2090/378A61B2090/3954A61B2562/0219A61B5/015A61B5/1127A61B5/7257A61B8/4245A61B8/5207A61B8/5223A61N2007/0052A61N2007/0073G01K11/26G06N3/08G06T2207/10132G06T2207/30096G06T7/0012
    • Ultrasound device configured to carry out a HIFU treatment and to detect in real time during the HIFU treatment the temperature distribution in the area of treatment, comprising: an ultrasound probe comprising at least an array of piezoelectric or CMUT transducers, - piloting means of said ultrasound probe, computing means configured to receive and store said raw ultrasound signals reflected by said tissues and acquired by each of said piezoelectric or CMUT transducers, to process said reflected raw ultrasound signals in order to generate an ultrasound image, as well as to carry out other processing on said raw ultrasound signals reflected by said tissues, characterized in that computer programs are loaded on said computing means, configured to carry out the method for determining the actual acoustic heating rate of tissues, comprising the following steps: a) identifying, inside an ultrasound image (14), a region of interest (15) inside which an area to be treated (16) is provided, b) assigning a starting temperature distribution, by means of which a temperature value is assigned to each point of ROI, c) emitting a high intensity ultrasound beam (100) focused on a focal point (11) contained in said ROI for a predetermined time interval, and subsequently a broadband ultrasound pulse (200), and detecting the ultrasound signal reflected and/or emitted by the tissues under treatment, d) carrying out the frequency transform of said reflected ultrasound signal in response to said broadband ultrasound pulse (200), in order to obtain a reference frequency spectrum (200s), e) repeating steps c) and d) iteratively, thus obtaining a frequency spectrum for each iteration, f) assuming that the temperature at the focus (11) is equal to a predetermined temperature and function of the tissue in the treatment step when the frequency spectrum (202s) detected in response to a broadband ultrasound pulse (202) comprises a plurality of peaks (2021) not provided in the reference frequency spectrum (200s), g) determining the actual acoustic heating rate Q as a function of said predetermined temperature, of the intensity of said high intensity ultrasound beam (100).