专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2015163961A2 BETA AND ALPHA EMISSION TOMOGRAPHY FOR THREE-DIMENSIONAL AUTORADIOGRAPHY 审中-公开
标题翻译：用于三维自动图像的BETA和ALPHA排放测量
公开(公告)号：WO2015163961A2
公开(公告)日：2015-10-29
申请号：PCT/US2015/014223
申请日：2015-02-03
申请人： THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA , INVICRO, LLC
发明人： BARRETT, Harrison H. , MILLER, Brian , DING, Yijun , CHEN, Liying , HOPPIN, John William , CAUCCI, Luca
IPC分类号： A61B5/1468
CPC分类号： G01T1/2942 , A61B6/037 , A61B6/4258 , A61B6/5205 , G01T1/161 , G01T1/2985 , G01T5/08
摘要： The present invention provides methods and systems for 3D imaging of in vivo and ex vivo tissues. The disclosed systems and methods employ an autoradiographic approach where particles emitted by a radioactive composition within the tissue are detected. Once detected, a 3D representation of the source of particles within the tissue is reconstructed for viewing and analysis.
摘要翻译：本发明提供用于体内和离体组织的3D成像的方法和系统。所公开的系统和方法采用放射自显影方法，其中检测由组织内的放射性组合物发射的颗粒。一旦检测到，组织内的颗粒源的3D表示被重建用于观察和分析。

2. 发明申请

WO1997034164A1 AUTORADIOGRAPHY IMAGING 审中-公开
标题翻译：自动图像成像
公开(公告)号：WO1997034164A1
公开(公告)日：1997-09-18
申请号：PCT/EP1997001200
申请日：1997-03-10
申请人： SIMAGE OY , ORAVA, Risto, Olavi , PYYHTIÄ, Jouni, Ilari , SCHULMAN, Tom, Gunnar , SARAKINOS, Miltiadis, Evangelos , SPARTIOTIS, Konstantinos, Evangelos
发明人： SIMAGE OY
IPC分类号： G01T01/29
CPC分类号： G01T1/2942
摘要： A method of autoradiography imaging includes steps of: (a) forming a subject having at least first and second markers, each marker providing radiation having a characteristic energy distribution; (b) detecting radiation from the marked subject using a semiconductor radiation detector having an array of cells, each cell recording a charge value dependent on the energy of incident radiation; (c) processing the output from the cells including discriminating charge values within at least two charge value ranges and allocating a display colour value to each pixel cell position in the array dependent upon the recorded charge value; and (d) forming an image for display with individual cell positions having a colour representative of the colour values. The method enables multiple label or multiple marker imaging in autoradiography to be performed by energy discriminating imaging, thus enhancing experimental accuracy and reproducibility.
摘要翻译：放射自显影成像的方法包括以下步骤：（a）形成具有至少第一和第二标记的对象，每个标记提供具有特征能量分布的辐射; （b）使用具有单元阵列的半导体辐射检测器检测来自标记对象的辐射，每个单元记录取决于入射辐射能量的电荷值; （c）处理来自所述单元的输出，包括在至少两个电荷值范围内的识别电荷值，并且根据所记录的电荷值，将显示颜色值分配给所述阵列中的每个像素单元位置; 和（d）形成用于显示具有代表颜色值的颜色的各个单元位置的图像。该方法能够通过能量鉴别成像进行放射自显影中的多标记或多标记成像，从而提高实验准确性和再现性。

3. 发明申请

WO1997014061A1 DETECTOR AND METHOD FOR AUTORADIOGRAPHY 审中-公开
标题翻译：检测器和自动方法
公开(公告)号：WO1997014061A1
公开(公告)日：1997-04-17
申请号：PCT/GB1996002238
申请日：1996-09-10
申请人： UNIVERSITY OF LEICESTER , FRASER, George, William , LEES, John, Ernest
发明人： UNIVERSITY OF LEICESTER
IPC分类号： G01T01/28
CPC分类号： G01T1/28 , G01T1/2942
摘要： There is disclosed a detector for autoradiography, the detector comprising a substantially radioisotope free microchannel plate (MCP) detector, the dimensions of the active area of said detector being substantially comparable with, or greater than, the working field of the autoradiography sample; and MCP signal collection means.
摘要翻译：公开了一种用于放射自显影的检测器，该检测器包括基本上无放射性同位素的微通道板（MCP）检测器，所述检测器的有效面积的尺寸基本上与放射自显影样品的工作场相当或大于; 和MCP信号采集装置。

4. 发明申请

WO1996019739A2 ASSAY APPARATUS 审中-公开
标题翻译：测定装置
公开(公告)号：WO1996019739A2
公开(公告)日：1996-06-27
申请号：PCT/EP1995005132
申请日：1995-12-22
申请人： KARO BIO AB , HAGGBLAD, Johan , ÖSTERLUND, Marie
发明人： KARO BIO AB
IPC分类号： G01T01/29
CPC分类号： B01L3/5023 , B01L2300/12 , B01L2400/0406 , G01T1/203 , G01T1/2942
摘要： The invention provides a solid support for example for use in a radioligand binding assay, the solid support comprising a plurality of interconnected elements arranged to provide interstitial spaces in which a liquid can flow. When a liquid sample is applied to a surface of the support of the invention it spreads across the surface of the support to a certain extent and also flows into the support on the surfaces of the interconnected elements which form the support and into the interstitial spaces therebetween. The support of the invention may be used as a support for a chemical reaction or for cell growth.
摘要翻译：本发明提供了例如用于放射性配体结合测定中的固体支持物，所述固体支持物包括多个互连元件，所述多个互连元件布置成提供液体可以在其中流动的间隙空间。当将液体样品施加到本发明的支撑体的表面上时，其在一定程度上分布在支撑体的表面上，并且也流入形成支撑件的互连元件的表面中的支撑件中并进入其间的间隙空间。本发明的载体可用作化学反应或细胞生长的载体。

5. 发明申请

WO2015163961A3 BETA AND ALPHA EMISSION TOMOGRAPHY FOR THREE-DIMENSIONAL AUTORADIOGRAPHY 审中-公开
标题翻译：用于三维自动图像的BETA和ALPHA排放测量
公开(公告)号：WO2015163961A3
公开(公告)日：2016-03-24
申请号：PCT/US2015014223
申请日：2015-02-03
申请人： UNIV ARIZONA STATE , INVICRO LLC
发明人： BARRETT HARRISON H , MILLER BRIAN , DING YIJUN , CHEN LIYING , HOPPIN JOHN WILLIAM , CAUCCI LUCA
IPC分类号： G01T5/02
CPC分类号： G01T1/2942 , A61B6/037 , A61B6/4258 , A61B6/5205 , G01T1/161 , G01T1/2985 , G01T5/08
摘要： The present invention provides methods and systems for 3D imaging of in vivo and ex vivo tissues. The disclosed systems and methods employ an autoradiographic approach where particles emitted by a radioactive composition within the tissue are detected. Once detected, a 3D representation of the source of particles within the tissue is reconstructed for viewing and analysis.
摘要翻译：本发明提供用于体内和离体组织的3D成像的方法和系统。所公开的系统和方法采用放射自显影方法，其中检测由组织内的放射性组合物发射的颗粒。一旦检测到，组织内的颗粒源的3D表示被重建用于观察和分析。

6. 发明申请

WO02007600A2 TEST BODY AND TEST BODY SYSTEMS, PRODUCTION AND USE THEREOF 审中-公开
标题翻译：设备和PRÜFKÖRPERSYSTEME，生产和使用
公开(公告)号：WO02007600A2
公开(公告)日：2002-01-31
申请号：PCT/DE2001/002721
申请日：2001-07-14
IPC分类号： G01T1/169 , G01T1/29 , G21G4/06 , G21G4/08 , A61B6/00
CPC分类号： G21G4/08 , A61B6/037 , A61B6/583 , G01T1/169 , G01T1/2942 , G21G4/06
摘要： The invention relates to a test body for nuclear medicine devices, such as, for example, for positron emission tomographs (PET), single photon tomographs (SPECT) or also for autoradiography. The test body comprises a solid body which itself emits gamma radiation or positrons. The disadvantages of a test body filled with a radioactive fluid can thus be routinely overcome. According to the invention, the production of said bodies permits structures smaller than 1mm, in particular, smaller than 0.1mm. Said test body can be used for positron emission tomography (PET) as well as for autoradiography as the test body can emit gamma radiation as well as positrons.
摘要翻译：本发明涉及一种用于核医疗设备，例如正电子发射断层扫描（PET），单光子断层摄影术（SPECT），或进行放射自显影幻像。该试验片具有固体，将其本身发出的伽马辐射或正电子。一个充满放射性液体标本的缺点是可以克服的，以便定期。本发明的试样的制备可以构建小于1mm，特别是小于0.1mm。本发明的试验片可以为两个正电子发射断层扫描（PET）以及放射自显影中使用的第一次使用，因为该试验片可以发射两γ辐射和正电子的辐射。

7. 发明申请

WO1990000747A1 METHOD AND APPARATUS FOR QUANTITATIVE AUTORADIOGRAPHY ANALYSIS 审中-公开
标题翻译：定量自动分析的方法和装置
公开(公告)号：WO1990000747A1
公开(公告)日：1990-01-25
申请号：PCT/GB1989000760
申请日：1989-07-06
申请人： OXFORD POSITRON SYSTEMS LIMITED , JEAVONS, Alan, Paul
发明人： OXFORD POSITRON SYSTEMS LIMITED
IPC分类号： G01T01/185
CPC分类号： G01T1/2942 , G01T1/185 , H01J47/02
摘要： Apparatus and method for quantitative autoradiography analysis involving beta-ray radiation comprises a converter (2) and wire chamber (3) in association with a membrane which provides a seal for the housing in which the converter and wire chamber are accommodated, the membrane also providing a ''window'' for the radioactive samples.
摘要翻译：涉及β射线辐射的定量放射自显影分析的装置和方法包括与膜相关联的转换器（2）和线室（3），所述膜为容纳转换器和线室的壳体提供密封，膜还提供放射性样品的“窗口”。

8. 发明申请

WO1987007033A1 SCINTILLATING SHEET SENSOR APPARATUS 审中-公开
标题翻译：扫描片传感器设备
公开(公告)号：WO1987007033A1
公开(公告)日：1987-11-19
申请号：PCT/GB1987000309
申请日：1987-05-11
申请人： FLOR-HENRY, Michel
IPC分类号： G01T01/00
CPC分类号： G01T1/2018 , G01T1/2914 , G01T1/2942
摘要： The apparatus comprises a CCD mounted in close proximity to a scintillating sheet sample (7) such as a chromatogram or gel, the radiation emitted from the sample being received directly by the CCD. The CCD can be of elongate construction and be scanned across the surface of a sample or can be an n x m array, having a very large number of pixels, which is placed directly against the sample sheet.
摘要翻译：该装置包括安装在诸如色谱图或凝胶之类的闪烁片样品（7）附近的CCD，从样品直接接收由CCD接收的辐射。 CCD可以是细长的结构，并且被扫描在样品的表面上，或者可以是具有非常大数量的像素的n×m阵列，其被直接放置在样品片上。

9. 发明申请

WO2016077479A1 PARTICLE EMISSION TOMOGRAPHY 审中-公开
标题翻译：颗粒排放测量
公开(公告)号：WO2016077479A1
公开(公告)日：2016-05-19
申请号：PCT/US2015/060198
申请日：2015-11-11
申请人： THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA , INVICRO, LLC
发明人： BARRETT, Harison H. , DING, Yijun , CAUCCI, Luca , HOPPIN, John William
IPC分类号： A61B6/03 , G01B7/004 , G01N15/02 , G01T1/16 , G01T1/164 , G01T1/29
CPC分类号： G01N15/0227 , A61B6/037 , A61B6/4241 , A61B6/4258 , A61B6/5205 , G01B7/004 , G01N15/02 , G01T1/2942
摘要： The present invention provides autoradiography methods and systems for imaging via the detection of alpha particles, beta particles, or other charged particles. Embodiments of the methods and systems provide high-resolution 3D imaging of the distribution of a radioactive probe, such as a radiopharmaceutical, on a tissue sample. Embodiments of the present methods and systems provide imaging of tissue samples by reconstruction of a 3D distribution of a source of particles, such as a radiopharmaceutical. Embodiments of the methods and systems provide tomographic methods including microtomography, macrotomography, cryomicrotomography and cryomacrotomography.
摘要翻译：本发明提供了用于通过检测α粒子，β粒子或其它带电粒子进行成像的放射自显影方法和系统。方法和系统的实施方案提供了在组织样品上放射性探针如放射性药物的分布的高分辨率3D成像。本方法和系统的实施例通过重建诸如放射性药物的颗粒源的3D分布来提供组织样本的成像。方法和系统的实施例提供了包括微影像学，宏观成像术，低温微影像学和低温射线照相术在内的断层摄影方法。

10. 发明申请

WO0207600A3 TEST BODY AND TEST BODY SYSTEMS FOR NUCLEAR MEDICINE DEVICES, PRODUCTION AND USE THEREOF 审中-公开
标题翻译：设备和PRÜFKÖRPERSYSTEME对核医疗设备以及其生产和使用
公开(公告)号：WO0207600A3
公开(公告)日：2002-05-23
申请号：PCT/DE0102721
申请日：2001-07-14
申请人： FORSCHUNGSZENTRUM JUELICH GMBH , WEBER SIMONE
发明人： WEBER SIMONE
IPC分类号： G01T1/169 , G01T1/29 , G21G4/06 , G21G4/08
CPC分类号： G21G4/08 , A61B6/037 , A61B6/583 , G01T1/169 , G01T1/2942 , G21G4/06
摘要： The invention relates to a test body for nuclear medicine devices, such as, for example, for positron emission tomographs (PET), single photon tomographs (SPECT) or also for autoradiography. The test body comprises a solid body which itself emits gamma radiation or positrons. The disadvantages of a test body filled with a radioactive fluid can thus be routinely overcome. According to the invention, the production of said bodies permits structures smaller than 1mm, in particular, smaller than 0.1mm. Said test body can be used for positron emission tomography (PET) as well as for autoradiography as the test body can emit gamma radiation as well as positrons.
摘要翻译：本发明涉及一种用于核医疗设备，例如正电子发射断层扫描（PET），单光子断层摄影术（SPECT），或进行放射自显影幻像。该试验片具有固体，将其本身发出的伽马辐射或正电子。一个充满放射性液体标本的缺点是可以克服的，以便定期。本发明的试样的制备可以构建小于1mm，特别是小于0.1mm。本发明的试验片可以为两个正电子发射断层扫描（PET）以及放射自显影中使用的第一次使用，因为该试验片可以发射两γ辐射和正电子的辐射。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式