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    • 5. 发明申请
    • IMPROVED NMR CRYOMAS PROBE FOR HIGH-FIELD WIDE-BORE MAGNETS
    • 用于高场宽磁铁的改进的核磁共振探针
    • WO2008070430A1
    • 2008-06-12
    • PCT/US2007/085040
    • 2007-11-18
    • DOTY SCIENTIFIC, INC.DOTY, F., DavidSHEVGOOR, Siddarth
    • DOTY, F., DavidSHEVGOOR, Siddarth
    • G01R33/44G01V3/00
    • G01R33/307G01R33/31G01R33/34015G01R33/34092
    • All critical circuit components, including the sample coils, are located along with the spinner assembly in a region that may be evacuated to high vacuum for thermal insulation and high-voltage operation. A hermetically sealed spinner assembly simultaneously satisfies the requirements of hermeticity, low total emissivity, rf compatibility, spinning performance, magnetic compatibility, and high filling factor by utilizing metal construction except for the central region near the rf sample coils. Hence, it is possible to maintain high vacuum in the region external to the MAS spinner assembly even over a broad range of bearing and drive gas temperatures. A bundle of optical fibers is provided for tachometry for spin rates up to 60 kHz. The use of alumina disc capacitors allows the noise contributions from the most critical capacitors to be reduced to a minor fraction of the total and simplifies high voltage operation.
    • 包括样品线圈在内的所有关键电路部件都与旋转器组件一起位于可以抽真空至高真空以进行绝热和高压操作的区域中。 密封的旋转器组件通过利用除了rf样品线圈附近的中心区域之外的金属结构,同时满足气密性,低总发射率,低相容性,旋转性能,磁兼容性和高填充系数的要求。 因此,即使在宽范围的轴承和驱动气体温度下,也可以在MAS旋转器组件外部的区域中保持高真空。 提供一束光纤用于高达60 kHz的旋转速度的转速。 使用氧化铝盘式电容器可以将最关键的电容器的噪声贡献降低到总体的一小部分,并简化高压运行。
    • 6. 发明申请
    • NMR MAS PROBE WITH CRYOGENICALLY COOLED CRITICAL CIRCUIT COMPONENTS
    • 具有低温冷却关键电路组件的NMR MAS探针
    • WO2006075213A3
    • 2006-12-07
    • PCT/IB2005053854
    • 2005-11-22
    • DOTY SCIENT INCDOTY DAVID F
    • DOTY DAVID F
    • G01V3/00
    • G01R33/307G01R33/31G01R33/3635Y10T29/43
    • A novel MAS probe is disclosed for obtaining a substantial improvement in signal to noise (S/N) in triple-resonance high-resolution (HR) magic-angle-spinning (MAS) NMR of samples near room temperature (RT) in high field magnets, especially where the RT shim bore is less than 55 mm. Critical circuit components other than the sample coils, including both high-power capacitors and inductors for one or more channels are located in a small, thermally insulated, cold zone immediately below the sample spinner assembly. Cooling these components to 100 K allows their thermal noise power to be conveniently reduced by a factor of three or more. Variable capacitors for fine tuning are located in an RT tuning zone below the cold zone. The circuit is designed such that the currents, voltages, and standing wave ratio (SWR) in circuit tuning elements in the RT tuning zone are relatively low, so rf losses and noise contributions below the cold zone may be only a few percent. The MAS probe is also compatible with magic angle gradients, automatic sample change, multi-nuclear tuning, variable temperature operation, field locking, and optical spin rate detection.
    • 公开了一种新颖的MAS探针,用于在高场中室温(RT)下的样品的三谐振高分辨率(HR)魔角旋转(MAS)NMR中获得信噪比(S / N)的实质性改善 磁铁,特别是RT垫片孔小于55 mm的地方。 除了样品线圈以外的关键电路元件,包括用于一个或多个通道的高功率电容器和电感器都位于样品旋转器组件正下方的小的绝热的冷区中。 将这些部件冷却至100 K可使其热噪声功率方便地降低三分之一以上。 用于微调的可变电容器位于冷区下方的RT调谐区域。 该电路被设计成使得RT调谐区中的电路调谐元件中的电流,电压和驻波比(SWR)相对较低,因此低于冷区的rf损耗和噪声贡献可能仅为百分之几。 MAS探头还兼容魔角梯度,自动样品更换,多核调谐,可变温度操作,场锁定和光学旋转速率检测。
    • 9. 发明申请
    • FLOW-THROUGH PROBE FOR NMR SPECTROMETERS
    • 用于NMR光谱仪的流通探测器
    • WO01020357A1
    • 2001-03-22
    • PCT/IL2000/000558
    • 2000-09-12
    • G01R33/20G01R33/30G01R33/31G01R33/34G01R33/46G01V3/00
    • G01R33/31G01R33/34092
    • There is disclosed an NMR probe including a body defining an internal chamber. This chamber is adapted for supporting a vacuum and the body is of a non-magnetic material. A conduit extends through the chamber in the body. The conduit has a first portion in communication with second portions, the first portion being intermediate the second portions, with the first and second portions of non-magnetic materials with substantially equal thermal expansion coefficients. An RF coil is positioned along at least a substantial portion of the first conduit portion. It is preferred that this device also include a field or frequency lock unit in the chamber, as well as a getter, to allow for degassing in the chamber to maintain the preferred high pressure vacuum. A method of using this NMR probe for NMR analysis is also disclosed.
    • 公开了一种NMR探针,其包括限定内腔的主体。 该室适于支撑真空并且本体是非磁性材料。 导管延伸穿过体内的腔室。 导管具有与第二部分连通的第一部分,第一部分在第二部分之间,非磁性材料的第一和第二部分具有基本相等的热膨胀系数。 RF线圈沿着第一导管部分的至少大部分被定位。 优选地,该装置还包括腔室中的场或频率锁定单元以及吸气剂,以允许室中的脱气以保持优选的高压真空。 还公开了使用该NMR探针进行NMR分析的方法。