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    • 1. 发明申请
    • IMPROVEMENTS IN AND RELATING TO CELL HARVESTING APPARATUS
    • 与细胞收获设备相关的改进
    • WO2017109085A1
    • 2017-06-29
    • PCT/EP2016/082404
    • 2016-12-22
    • GE HEALTHCARE BIO-SCIENCES CORP.GE HEALTHCARE UK LIMITED
    • HARRIS, DanDOWLING, Jim
    • C12M1/00F16K7/06A61M39/28F16K7/04C12M1/34
    • C12M47/02A61M39/281C12M23/00C12M23/26C12M41/00F16K7/045F16K7/065
    • Disclosed herein is a cell harvesting instrument suitable for concentrating cells from a source suspension of cells and/or washing said cells, the instrument comprising: a housing for accommodating mechanical elements including at least one fluid pump, at least one valve; and a processing kit removably insertable into the housing, said kit including a generally fiat frame having or supporting plural sealed fluid paths arranged in a generally fiat plane and such that fluids in the paths do not contact said mechanical elements, wherein at least portions of the fluid paths comprise flexible tubes, the outer surfaces of which are manipulateable by the or each fluid pump, to provide fluid flow in one or more of the paths and /or by the or each valve to restrict fluid flow in one or more of the paths. In an embodiment, the kit comprises also a fluid processing reservoir and a filter suitable for separating cells from fluid in said paths. A transfer mechanism for moving and weighing the fluid processing reservoir is disclosed also.
    • 本文公开了适用于从细胞的源悬浮液中浓缩细胞和/或洗涤所述细胞的细胞收集器械,所述器械包括:壳体,用于容纳机械元件,所述机械元件包括至少一个流体泵,在 至少一个阀门; 以及可拆卸地插入壳体中的处理套件,所述套件包括大致平坦的框架,该框架具有或支撑布置在大致平坦平面中的多个密封流体路径,并且使得路径中的流体不接触所述机械元件,其中至少部分 流体路径包括柔性管,柔性管的外表面可由所述流体泵或每个流体泵操纵,以在一个或多个路径中和/或由所述或每个阀提供流体流动以限制流体在一个或多个路径中流动 。 在一个实施例中,该套件还包括流体处理容器和适于在所述路径中将流体与流体分离的过滤器。 还公开了用于移动和称重流体处理容器的传输机构。
    • 3. 发明申请
    • LEAF CLAMP FOR TUBING
    • LEAF夹具用于管道
    • WO2008144726A1
    • 2008-11-27
    • PCT/US2008/064354
    • 2008-05-21
    • HALKEY-ROBERTS CORPORATION
    • MACKAL, Glenn, H.
    • A61M5/00
    • F16K7/065A61M39/284F16K7/066
    • A leaf clamp for installation on tubing to control the flow of fluid therethrough, the leaf clamp comprising opposing rectilinear frameworks between which the tubing is threaded. A flexible leaf interconnects the opposing frameworks and extends generally parallel above the tubing positioned between the rectilinear frameworks. A snap-lever, generally L-shaped, is pivotally connected between the upper portions of the frameworks such that the shorter leg of the L-shaped lever is aligned with and engages the leaf member to urge it downwardly into engagement with the tubing as the longer leg of the L- shaped snap-lever is pivoted from a generally transverse "open" position to a generally parallel "closed" position.
    • 用于安装在管道上以控制流体通过其中的流动叶片的叶片夹,包括相对的直线框架,管道在其之间被螺纹连接。 柔性叶片将相对的框架相互连接,并且大体上平行于位于直线框架之间的管道上方。 通常为L形的卡扣杆枢转地连接在框架的上部之间,使得L形杠杆的较短的腿与叶片构件对准并与叶片构件接合,以将其向下推动与管道接合 L形卡扣杆的较长的腿从大致横向的“打开”位置枢转到大致平行的“关闭”位置。
    • 8. 发明申请
    • FLOW CONTROL VALVE AND METHOD FOR CONTROLLING FLOW
    • 流量控制阀和控制流量的方法
    • WO00027539A1
    • 2000-05-18
    • PCT/GB1999/003708
    • 1999-11-10
    • B04C5/16B04C11/00F16K7/06
    • B04C11/00B04C5/16F16K7/065
    • A flow control valve for use for example in the case of a cyclone separator. The valve comprises a body (3) which defines a passageway through which flow is to be controlled. The passageway is lined with a deformable liner (13) extending along an inwardly facing wall of a passageway and supported by the body such that a seal is formed to prevent flow between the liner and the inwardly facing passageway wall. The internal cross section of the liner is controlled by selectively displacing the liner away from the inwardly facing wall of the passageway. Flow through the valve may be sensed by sensors such as conductivity or other sensors incorporated in the valve or upstream of the valve, and the liner may be deformed in response to fluctuations in the sensed flow.
    • 用于例如在旋风分离器的情况下使用的流量控制阀。 该阀包括一个主体(3),该主体(3)限定了一个要控制流量的通道。 通道衬有可沿通道的面向内壁延伸的可变形衬套(13),该壁可由主体支撑,从而形成密封件以防止衬套与面向内的通道壁之间的流动。 衬垫的内部横截面通过选择性地将衬套远离通道的面向内壁的位置来控制。 通过阀门的流量可以由传感器(例如导入阀或其中包含在阀门中的其它传感器或阀的上游)感测,并且衬套可以响应于感测流量的波动而变形。
    • 9. 发明申请
    • CONTROLLED VALVE FOR FLOW REGULATION OF GAS OR LIQUID AND USE OF SUCH VALVE
    • 用于气体或液体的流动调节的控制阀和这种阀的使用
    • WO1991019124A1
    • 1991-12-12
    • PCT/NO1991000078
    • 1991-05-24
    • ABB TRALLFA ROBOT A/SANFINDSEN, Ole, Arnt
    • ABB TRALLFA ROBOT A/S
    • F16K07/06
    • F16K7/065
    • An adjustable control valve for flow regulation of gas or liquid has a controlled hose clamp device, preferably with two clamping members (K1, K2) disposed on respective sides of a hose (A) for adjustable compression of the hose and thereby setting of the flow cross-section of the hose at a compression site between the clamping members. The control valve comprises further a movable cam disk, e.g. a rotatable eccentric sheave (E), actuated by a shifting mechanism, preferably a step motor, disposed for variable compression of the hose in accordance with the position of the cam disk or eccentric sheave. For automatically controlled setting of the flow cross-section of the hose, the shifting mechanism may be arranged to be controlled from measuring means mounted for gauging the flow in the hose (A) downstream of the compression site (As). In practice such regulation may be used for controlling the quantity ratios between the supplies of paint, jet formation air and atomizing air, respectively, to an atomizing gun (P), preferably by means of a common data processing unit (D) inserted between the control valve (Sa, Sp, Sf) and measuring means (Ma, Mp, Mf) in all control loops (Qa, Qp, Qf) for the supplies of paint, jet formation air and atomizing air, respectively, to the spray gun (P).
    • 用于气体或液体流量调节的可调控制阀具有受控的软管夹紧装置,优选地具有设置在软管(A)的相应侧上的两个夹紧构件(K1,K2)),用于软管的可调压缩,从而设定流量 在夹紧构件之间的压缩部位处的软管的横截面。 控制阀还包括可移动的凸轮盘,例如。 由可移动机构致动的可旋转的偏心滑轮(E),优选地是步进马达,其设置成根据凸轮盘或偏心滑轮的位置可变地压缩软管。 为了自动控制软管的流动横截面的设置,换档机构可以布置成由用于测量压缩部位(As)下游的软管(A)中的流量的测量装置来控制。 在实践中,这种调节可以用于分别控制喷射喷射空气和雾化空气分别供应给雾化枪(P)之间的量比,优选地通过插入在喷雾形成空气中的公共数据处理单元(D) 控制阀(Sa,Sp,Sf)和测量装置(Ma,Mp,Mf)分别用于喷枪供应油漆,喷射形成空气和雾化空气的所有控制回路(Qa,Qp,Qf) P)。