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1. 发明申请

WO2009091560A1 INTRAUTERINE FALLOPIAN TUBE OCCLUSION DEVICE 审中-公开
公开(公告)号：WO2009091560A1
公开(公告)日：2009-07-23
申请号：PCT/US2009/000241
申请日：2009-01-15
申请人： YALE UNIVERSITY , CONTRAMED LLC , TAL, Michael, G. , GUTELIUS, Patrick, N. , DEBISSCHOP, Mark, J. , SHIKHMAN, Oleg
发明人： TAL, Michael, G. , GUTELIUS, Patrick, N. , DEBISSCHOP, Mark, J. , SHIKHMAN, Oleg
IPC分类号： A61F6/14
CPC分类号： A61F6/18 , A61F6/20
摘要： An intrauterine device for occluding orifices of fallopian tubes includes a resilient body having an elongated member with a first end and a second end. The elongated member further includes a first leg ending with the first end of the elongated member, a second leg ending with the second end of the elongated member and a connection member positioned therebetween. A first orifice plug is secured at the first end of the elongated member and a second orifice plug is secured at the second end of the elongated member. The first and second orifice plugs are shaped and dimensioned to seat at the orifices of the fallopian tubes or within the fallopian tubes as the elongated member spreads outwardly with the first end and second end moving apart.
摘要翻译：用于阻塞输卵管孔的子宫内装置包括弹性体，其具有带有第一端和第二端的细长构件。细长构件还包括以细长构件的第一端为终点的第一腿部，以细长构件的第二端为末端的第二腿部和位于其间的连接构件。在细长构件的第一端处固定第一孔口塞，并且在细长构件的第二端处固定第二孔塞。第一和第二孔塞的形状和尺寸被设计成位于输卵管的孔口或输卵管内，因为当第一端和第二端移开时，细长构件向外扩展。

2. 发明申请

WO2012027090A1 INTRAUTERINE DEVICE 审中-公开
标题翻译： INTRAUTERINE设备
公开(公告)号：WO2012027090A1
公开(公告)日：2012-03-01
申请号：PCT/US2011/046921
申请日：2011-08-08
申请人： YALE UNIVERSITY , CONTRAMED LLC , TAL, Michael, G. , GUTELIUS, Patrick, N. , DEBISSCHOP, Mark, J. , SHIKHMAN, Oleg , PATRIZIO, Pasquale
发明人： TAL, Michael, G. , GUTELIUS, Patrick, N. , DEBISSCHOP, Mark, J. , SHIKHMAN, Oleg , PATRIZIO, Pasquale
IPC分类号： A61F6/22
CPC分类号： H04R1/323 , A61F6/142 , A61F6/18 , A61F6/20 , B60R11/0217 , H04R1/026 , H04R1/24 , H04R5/02 , H04R2499/13
摘要： An intrauterine device for applying pressure to the walls of the uterine cavity includes a resilient body having an elongated member which includes a first end and a second end which are resiliently biased away from each other. The first end of the elongated member includes a first leg having a first end and a second end. The second end of the elongated member includes a second leg having a first end and a second end. A first plug member is secured at the second end of the first leg and a second plug member is secured at the first end of the second leg. The first and second plug members are shaped and dimensioned for bearing against the walls of the uterine cavity as the elongated member spreads outwardly with the first end and the second end moving apart. A method for preventing conception within the uterine cavity is also disclosed.
摘要翻译：用于向子宫腔的壁施加压力的子宫内装置包括具有细长构件的弹性体，该细长构件包括彼此弹性偏压的第一端和第二端。细长构件的第一端包括具有第一端和第二端的第一腿。细长构件的第二端包括具有第一端和第二端的第二腿。第一插头构件固定在第一腿的第二端，并且第二插头构件固定在第二腿的第一端。当第一端部和第二端部移开时，第一和第二插塞构件的形状和尺寸被设计成用于承载在子宫腔的壁上，因为细长构件向外扩展。还公开了一种防止子宫腔内受孕的方法。

3. 发明申请

WO2008060396A2 METHOD AND APPARATUS FOR TREATMENT OF THROMBOSED HEMODIALYSIS ACCESS GRAFTS AND ARTERIO VENOUS FISTULAS 审中-公开
标题翻译：用于治疗血栓形成细胞浸润细胞培养物和异常静脉注射液的方法和装置
公开(公告)号：WO2008060396A2
公开(公告)日：2008-05-22
申请号：PCT/US2007/022792
申请日：2007-10-29
申请人： YALE UNIVERSITY , TAL, Michael, G.
发明人： TAL, Michael, G.
IPC分类号： A61M29/00
CPC分类号： A61M25/1002 , A61M25/0023 , A61M25/0032 , A61M2025/1079
摘要： A catheter includes a catheter body with a compliant balloon secured at a distal end of the catheter body, the balloon including a proximal end and a distal end, a first lumen in fluid communication with the balloon, a second lumen in fluid communication with at least one infusion aperture directly adjacent the proximal end of the balloon, and a third lumen in fluid communication with a port positioned distally of the balloon. A method for using the catheter is also provided.
摘要翻译：导管包括导管主体，其具有固定在导管主体的远端处的顺应性气囊，所述气囊包括近端和远端，与气囊流体连通的第一腔，至少与第二腔流体连通的第二腔直接邻近球囊近端的一个输注孔，以及与位于气囊远端的端口流体连通的第三腔。还提供了一种使用该导管的方法。

4. 发明申请

WO2006055780A2 SHEATH/CATHETER SYSTEM WITH CONTROLLED HARDNESS AND FLEXIBILITY 审中-公开
标题翻译：具有控制硬度和灵活性的管道/导管系统
公开(公告)号：WO2006055780A2
公开(公告)日：2006-05-26
申请号：PCT/US2005/041832
申请日：2005-11-18
申请人： YALE UNIVERSITY , TAL, Michael, G. , ANDERSON, Janelle, R.
发明人： TAL, Michael, G. , ANDERSON, Janelle, R.
IPC分类号： A61M25/00
CPC分类号： A61M25/0054 , A61M25/0052 , A61M25/0053 , A61M2025/0004 , A61M2025/0036 , A61M2025/004 , A61M2025/0063 , A61M2025/0175 , A61M2025/0681
摘要： A sheath/catheter system includes a catheter including a proximal end and a distal end, the distal end including a distal tip portion exhibiting controlled hardness and flexibility. The system also includes a sheath including a proximal end and a distal end. The system further includes a mechanism for controlling the hardness and flexibility of the distal tip portion of the catheter. A method for vascular access is achieved by introducing a catheter into a vessel, advancing a sheath over the catheter and into the vessel, altering the catheter or sheath to change the respective flexibility and hardness thereof and further advancing the catheter or sheath within the vascular system to a predetermined location.
摘要翻译：护套/导管系统包括包括近端和远端的导管，所述远端包括表现出受控的硬度和柔性的远侧末端部分。该系统还包括护套，其包括近端和远端。该系统还包括用于控制导管的远侧末端部分的硬度和柔性的机构。血管通路的方法是通过将导管引入血管，将护套推入导管并进入血管，改变导管或护套以改变其相应的柔韧性和硬度，并进一步推进血管系统内的导管或鞘到预定位置。

5. 发明申请

WO2004112569A3 VASCULAR ABLATION APPARATUS AND METHOD 审中-公开
公开(公告)号：WO2004112569A3
公开(公告)日：2004-12-29
申请号：PCT/US2004/015858
申请日：2004-05-20
申请人： YALE UNIVERSITY , TAL, Michael, G.
发明人： TAL, Michael, G.
IPC分类号： A61D1/02
摘要： An apparatus for the treatment of venous stasis includes an elongated intraluminal member shaped and dimensioned for passage through vessels of a subject. The intraluminal member includes a proximal end and a distal end. A conduit extends from proximate the proximal end of the intraluminal member to proximate the distal end of the intraluminal member. The conduit is shaped and dimensioned for fluid communication between the proximal end of the intraluminal member and the distal end of the intraluminal member. The distal end of the intraluminal member includes disruption means proximate thereto for ablating a predetermined vessel wall. A method is also provided for the treatment of venous stasis. The method is achieved by advancing an elongated intraluminal member through a vein to a treatment site, activating the intraluminal member for ablation of the treatment site and injecting sclerosant into the vein at the treatment site.

6. 发明申请

WO2006093787A2 VARICOSE VEIN DISSECTOR AND REMOVAL APPARATUS 审中-公开
标题翻译： VARICOSE VEIN分离器和拆卸装置
公开(公告)号：WO2006093787A2
公开(公告)日：2006-09-08
申请号：PCT/US2006/006425
申请日：2006-02-24
申请人： YALE UNIVERSITY , TAL, Michael, G.
发明人： TAL, Michael, G.
CPC分类号： A61B17/00008 , A61B2017/00349 , A61B2017/320056 , A61B2017/32113
摘要： A varicose vein dissector and removal apparatus includes a handle having a first end and a second end, a dissector extending from the first end of the handle and a hook extending from the second end of the handle, and a blade positioned within the dissector for movement between a use position and a storage position. The apparatus is used by creating an initial incision in skin over a varicose vein to be removed, advancing the dissector into the incision and dissecting around the varicose vein to be removed, pushing the dissector against an inner surface of the skin a predetermined distance from the initial incision, exposing the blade by moving it from its storage position to its use position and creating a second incision in the skin letting the dissector protrude out of the skin, and grasping the vein with the hook and removing the vein.
摘要翻译：静脉曲张分离器和去除装置包括具有第一端和第二端的手柄，从手柄的第一端延伸的解剖器和从手柄的第二端延伸的钩以及位于解剖器内的用于移动的刀片在使用位置和存储位置之间。该装置用于通过在静脉曲张上的皮肤上产生初始切口以被移除，将解剖器推进到切口中并在静脉曲张周围解剖以被去除，将解剖器推向皮肤的内表面，距离皮肤预定距离初始切口，通过将刀片从其存储位置移动到其使用位置并且在皮肤中创建第二切口使得解剖器从皮肤伸出并且用钩抓住静脉并移除静脉而使刀片暴露。

7. 发明申请

WO2005030291A2 METHOD AND APPARATUS FOR TREATMENT OF THROMBOSED HEMODIALYSIS ACCESS GRAFTS 审中-公开
标题翻译：用于治疗血栓形成的肝细胞癌的方法和装置
公开(公告)号：WO2005030291A2
公开(公告)日：2005-04-07
申请号：PCT/US2004/030981
申请日：2004-09-23
申请人： YALE UNIVERSITY , TAL, Michael, G.
发明人： TAL, Michael, G.
IPC分类号： A61M
CPC分类号： A61M25/10 , A61M25/0023 , A61M25/0029 , A61M25/0032 , A61M25/007 , A61M2025/1052
摘要： A method for the treatment of thrombosed hemodialysis access grafts or fistulas defining a shunt positioned between an arterial side and a venous side is achieved by inserting a balloon catheter within the shunt, wherein the balloon catheter includes a distal balloon and at least one infusion aperture located proximally of the distal balloon. Thereafter, the balloon catheter is advanced within an arterial anastomosis at an artery-shunt juncture and the distal balloon is inflated. A thrombolytic agent is then injected through the infusion apertures of the balloon catheter into the shunt to chemically destroy clot material within the shunt, wherein by applying the thrombolytic agent with the distal balloon inflated at the arterial anastomosis the possibility of the clot material moving into the artery is prevented and there is no need to worry about the migration of the clot into the arterial system and the resulting complications. Finally, the inflated distal balloon is pulled toward the venous side, eradicating the arterial plug. A balloon catheter for use in accordance with the present invention is also disclosed.
摘要翻译：一种用于治疗凝血性血液透析的方法，其通过将气囊导管插入所述分路内来实现定义位于动脉侧和静脉侧之间的分流器的入口移植物或瘘，其中所述气囊导管包括远端球囊和至少一个位于远端气球的近端。此后，气囊导管在动脉分流关节处在动脉吻合内前进，远端球囊膨胀。然后将血栓溶解剂通过气囊导管的输注孔注入分流器以化学破坏分流器内的凝块材料，其中通过将血栓溶解剂施用于在动脉吻合处充气的远端球囊，血块材料进入动脉被阻止，并且不需要担心血块向动脉系统的迁移以及由此导致的并发症。最后，充气的远端气囊被拉向静脉侧，消除动脉塞。还公开了根据本发明使用的气囊导管。

8. 发明申请

WO2004112569A2 VASCULAR ABLATION APPARATUS AND METHOD 审中-公开
标题翻译：血管收缩装置及方法
公开(公告)号：WO2004112569A2
公开(公告)日：2004-12-29
申请号：PCT/US2004/015858
申请日：2004-05-20
申请人： YALE UNIVERSITY , TAL, Michael, G.
发明人： TAL, Michael, G.
IPC分类号： A61B
CPC分类号： A61B17/00008 , A61B17/3207 , A61B17/320725 , A61B17/320758 , A61B2017/00778 , A61B2017/320004 , A61B2017/320012 , A61B2017/320733
摘要： An apparatus for the treatment of venous stasis includes an elongated intraluminal member shaped and dimensioned for passage through vessels of a subject. The intraluminal member includes a proximal end and a distal end. A conduit extends from proximate the proximal end of the intraluminal member to proximate the distal end of the intraluminal member. The conduit is shaped and dimensioned for fluid communication between the proximal end of the intraluminal member and the distal end of the intraluminal member. The distal end of the intraluminal member includes disruption means proximate thereto for ablating a predetermined vessel wall. A method is also provided for the treatment of venous stasis. The method is achieved by advancing an elongated intraluminal member through a vein to a treatment site, activating the intraluminal member for ablation of the treatment site and injecting sclerosant into the vein at the treatment site.
摘要翻译：用于治疗静脉淤滞的装置包括细长管腔内构件，其成形和尺寸设置用于通过受试者的血管。管腔内构件包括近端和远端。导管从管腔内构件的近端延伸到靠近管腔内构件的远端。导管的形状和尺寸用于腔内构件的近端和管腔内构件的远端之间的流体连通。管腔内构件的远端包括靠近其的破裂装置，用于烧蚀预定的血管壁。还提供了一种治疗静脉淤滞的方法。该方法通过将细长的管腔内部件通过静脉推进到治疗部位来实现，激活管腔内部件以消融治疗部位，并在治疗部位将静脉注射入静脉。

9. 发明申请

WO2008092029A2 ACCESS DEVICE 审中-公开
标题翻译：访问设备
公开(公告)号：WO2008092029A2
公开(公告)日：2008-07-31
申请号：PCT/US2008/051950
申请日：2008-01-24
申请人： ACCESS SCIENTIFIC, INC. , TAL, Michael, G. , ANDERSON, Janelle, R. , YAFFE, Benjamin, K. , MCCREIGHT, William, J. , RABINER, Robert, A.
发明人： TAL, Michael, G. , ANDERSON, Janelle, R. , YAFFE, Benjamin, K. , MCCREIGHT, William, J. , RABINER, Robert, A.
IPC分类号： A61M25/06
CPC分类号： A61M25/0606 , A61B17/34 , A61B17/3496 , A61B2017/347 , A61M25/0097
摘要： An access device places a medical article within a body space of a patient. The device has a needle section that includes an elongated body and a needle hub. The device further includes a dilator portion that has a dilator and a dilator hub. The dilator is coaxially disposed and slideable over the elongated body of the needle section. The device further includes a sheath section that has a sheath and a sheath hub. The sheath is coaxially disposed and slideable over the dilator. The device further includes a first locking mechanism operably disposed between the needle hub and the dilator hub to inhibit at least unintentional axial movement between the needle section and the dilator portion and a second locking mechanism operably disposed between the dilator hub and the sheath hub to inhibit at least unintentional axial movement between the dilator portion and the sheath section.
摘要翻译：访问设备将医疗用品放置在患者的身体空间内。该装置具有包括细长主体和针座的针部。该装置还包括具有扩张器和扩张器毂的扩张器部分。扩张器同轴地布置并可滑过针部分的细长主体。该装置还包括具有护套和护套毂的护套部分。护套同轴放置并可在扩张器上滑动。该装置还包括可操作地设置在针毂与所述扩张器毂之间以抑制针部和所述扩张器部和可操作地布置在扩张器毂和鞘轮毂，以抑制之间的第二锁定机构之间的至少意外轴向移动的第一锁定机构至少在扩张器部分和护套部分之间的无意的轴向移动。

10. 发明申请

WO2012068166A3 VASCULAR TREATMENT DEVICES AND METHODS 审中-公开
公开(公告)号：WO2012068166A3
公开(公告)日：2012-05-24
申请号：PCT/US2011/060860
申请日：2011-11-15
申请人： VASCULAR INSIGHTS LLC , TAL, Michael, G. , MARANO, John, P.
发明人： TAL, Michael, G. , MARANO, John, P.
IPC分类号： A61M5/14 , A61M25/09 , A61B17/34 , A61B17/03 , A61M5/178
摘要： An apparatus for performing a vascular treatment includes an intraluminal member that is controUingly moved during the vascular treatment. The intraluminal member of the vascular treatment device can be connected to a motor. The intraluminal member may be configured to retain endothelium during the vascular treatment procedure.

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