专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2010054156A2 VACCINES TARGETING CELLULAR DEATH RECEPTORS 审中-公开
标题翻译：疫苗靶向细胞死亡受体
公开(公告)号：WO2010054156A2
公开(公告)日：2010-05-14
申请号：PCT/US2009/063499
申请日：2009-11-06
申请人： WAYNE STATE UNIVERSITY , WEI, Wei-Zen , WU, Gen Sheng , PIECHOCKI, Marie P. , JONES, Richard F.
发明人： WEI, Wei-Zen , WU, Gen Sheng , PIECHOCKI, Marie P. , JONES, Richard F.
IPC分类号： A61K39/395
CPC分类号： A61K39/0011 , A61K38/193 , A61K39/39558 , A61K49/0004 , A61K2039/505 , A61K2039/53 , A61K2039/55522 , A61K2039/55544 , A61K2039/6037 , C07K16/2878 , C07K2317/73 , C07K2317/75 , G01N33/6854 , G01N2333/70578 , G01N2800/24
摘要： The invention provides therapeutics and methods to induce a mammalian host, including a human, to produce antibodies, which agonize death receptors and cause the apoptotic death of target cells within the host's body. The therapeutics are vaccine compositions, including genetic vaccines encoding death receptor antigens of the tumor necrosis factor receptor family. Also provided are means and methods for overcoming host immunological tolerance to death receptors. The vaccines are useful against cancer cells and other death receptor bearing target cells within the host, and can be used in both therapeutic and prophylactic settings. The vaccines are also useful for diagnostic testing of the immunocompetence of a host.
摘要翻译：本发明提供了诱导哺乳动物宿主（包括人）产生抗体的治疗剂和方法，所述抗体激动死亡受体并引起宿主体内靶细胞的凋亡性死亡。治疗剂是疫苗组合物，包括编码肿瘤坏死因子受体家族的死亡受体抗原的遗传疫苗。还提供了用于克服对死亡受体的宿主免疫耐受性的手段和方法。疫苗可用于治疗宿主内的癌细胞和其他带有死亡受体的靶细胞，并且可用于治疗和预防。疫苗也可用于诊断测试宿主的免疫活性。

2. 发明申请

WO2012162626A1 MULTI-TARGET DART GAME 审中-公开
标题翻译：多目标DART游戏
公开(公告)号：WO2012162626A1
公开(公告)日：2012-11-29
申请号：PCT/US2012/039618
申请日：2012-05-25
申请人： ARACHNID, INC. , RICE, Patrick G. , MALMBERG, Matthew S. , JONES, Richard F. , MYERS, Thomas P.
发明人： RICE, Patrick G. , JONES, Richard F. , MYERS, Thomas P.
IPC分类号： F41J3/00
CPC分类号： F41J3/0028 , F41J3/0061 , F41J5/052
摘要： A multiple target electronic dart gaming machine having shared electronic components. According to certain embodiments, the multiple targets are mounted on opposite sides of a game board of a target assembly that is housed in a cabinet of the gaming machine. The gaming machine may be floor-standing or wall mountable. Either affixed above the top of the target assembly, below the bottom of the target assembly, or both, is a visual display video monitor for providing players and observers with game scores and the like. The game board may be axially rotated between at least first and second positions so as to allow game play on the different targets. Additionally, the position of the game board may be detected through the use of a detector on or in the board.
摘要翻译：具有共享电子部件的多目标电子飞镖游戏机。根据某些实施例，多个目标安装在容纳在游戏机的机柜中的目标组件的游戏板的相对侧上。游戏机可以是落地式或壁挂式的。固定在目标组件的顶部上方，在目标组件的底部或两者之下的是用于向玩家和观察者提供游戏分数等的视觉显示视频监视器。游戏板可以在至少第一和第二位置之间轴向旋转，以便允许不同目标上的游戏。此外，可以通过在板上或板上使用检测器来检测游戏板的位置。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式