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1. 发明申请

WO2021247925A1 STRUCTURE-GUIDED IMMUNOTHERAPY AGAINST SARS-COV-2 审中-公开
公开(公告)号：WO2021247925A1
公开(公告)日：2021-12-09
申请号：PCT/US2021/035782
申请日：2021-06-03
申请人： VIR BIOTECHNOLOGY, INC. , UNIVERSITY OF WASHINGTON , HUMABS BIOMED SA , CORTI, Davide , SNELL, Gyorgy , CZUDNOCHOWSKI, Nadine , VEESLER, David , WALLS, Alexandra C. , PARK, Young-Jun , TORTORICI, M. Alejandra
发明人： CORTI, Davide , SNELL, Gyorgy , CZUDNOCHOWSKI, Nadine , VEESLER, David , WALLS, Alexandra C. , PARK, Young-Jun , TORTORICI, M. Alejandra
IPC分类号： A61P31/14 , C07K16/10 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/34 , C07K2317/76 , C07K2317/92
摘要： The instant disclosure provides antibodies and antigen-binding fragments thereof that can bind in certain regions of a SARS-CoV-2 S glycoprotein and can neutralize a SARS-CoV-2 infection. Also provided are immunogenic compositions that comprise a SARS-CoV-2 S glycoprotein or a portion thereof that is capable of being bound by an antibody or antigen-binding fragment.

2. 发明申请

WO2021203053A1 IMMUNOTHERAPY TARGETING A CONSERVED REGION IN SARS CORONAVIRUSES 审中-公开
公开(公告)号：WO2021203053A1
公开(公告)日：2021-10-07
申请号：PCT/US2021/025653
申请日：2021-04-02
申请人： VIR BIOTECHNOLOGY, INC. , UNIVERSITY OF WASHINGTON
发明人： CORTI, Davide , SNELL, Gyorgy , CZUDNOCHOWSKI, Nadine , VEESLER, David , WALLS, Alexandra, C. , PARK, Young-Jun
IPC分类号： C07K16/10 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/76 , C07K2317/92
摘要： The present disclosure provides a conserved target region of a SARS coronavirus receptor binding domain (RBD). Also provided are antibodies and antigen-binding fragments thereof that are capable of bind in a target region, in certain embodiments, are capable of neutralizing a SARS-CoV-2 infection. Also provided are immunogenic compositions derived from a target region, and methods of using the same to, for example, treat or prevent a sarbecovirus infection.

3. 发明申请

WO2008088171A1 ANCHOR 审中-公开
标题翻译：锚
公开(公告)号：WO2008088171A1
公开(公告)日：2008-07-24
申请号：PCT/KR2008/000286
申请日：2008-01-17
申请人： PARK, Jae-Man , PARK, Young-Jun , JUNG, Gyu-Jeom , SHIN, Byoung-Woo , JUNG, Yoon-Jine , KANG, Keum-Sik , KIM, Chul-Yeong , YOON, Sung-Il , UH, Pyong-Kyong , LEE, Hwa-Yong
发明人： PARK, Jae-Man , PARK, Young-Jun , JUNG, Gyu-Jeom , SHIN, Byoung-Woo , JUNG, Yoon-Jine , KANG, Keum-Sik , KIM, Chul-Yeong , YOON, Sung-Il , UH, Pyong-Kyong , LEE, Hwa-Yong
IPC分类号： E02D5/80
CPC分类号： E02D5/805
摘要： Provided is an anchor. The anchor including an anchor main body coupled to a plurality of tension members longitudinally disposed in one direction at its one end to be buried in a hole, includes: an anchor extension body including a hollow-shaped case coupled to the anchor main body to surround an outer periphery of the anchor main body, and a plurality of extensions disposed in a circumferential direction of the case to be spaced apart from each other, each of which extends from an end of the case in a longitudinal direction of the anchor main body; and an extension means for widening ends of the extensions of the anchor extension body toward an inner periphery of the hole such that the extensions press against the inner periphery of the hole to enlarge the hole.
摘要翻译：提供了一个锚点。所述锚固件包括锚固主体，所述锚固主体联接到在其一端纵向设置在一个方向上以被埋在孔中的多个张力构件，所述锚固主体包括：锚固件延伸体，其包括联接到所述锚固主体的环形壳体，锚固体主体的外周，以及沿壳体的圆周方向设置成彼此间隔开的多个延伸部，每个延伸部从壳体的端部沿着主体主体的长度方向延伸; 以及延伸装置，用于将锚固体延伸体的延伸部的端部朝向孔的内周加宽，使得延伸部压靠孔的内周，以扩大孔。

4. 发明申请

WO2008088172A1 METHOD OF REINFORCING GROUND 审中-公开
标题翻译：加固方法
公开(公告)号：WO2008088172A1
公开(公告)日：2008-07-24
申请号：PCT/KR2008/000287
申请日：2008-01-17
申请人： PARK, Jae-Man , PARK, Young-Jun , JUNG, Gyu-Jeom , SHIN, Byoung-Woo , JUNG, Yoon-Jine , KANG, Keum-Sik , KIM, Chul-Yeong , YOON, Sung-Il , UH, Pyong-Kyong , LEE, Hwa-Yong
发明人： PARK, Jae-Man , PARK, Young-Jun , JUNG, Gyu-Jeom , SHIN, Byoung-Woo , JUNG, Yoon-Jine , KANG, Keum-Sik , KIM, Chul-Yeong , YOON, Sung-Il , UH, Pyong-Kyong , LEE, Hwa-Yong
IPC分类号： E02D3/11
CPC分类号： E02D3/11 , E02D5/44
摘要： Provided is a method of reinforcing ground. The method of reinforcing ground includes: a hole piercing step of downwardly piercing the ground, in which a structure is constructed, to form a hole; a hole filling step of filling a grouting material into the hole; a hole enlarging step of transmitting energy to a metal mixture formed of metal oxide and metal powder to cause a thermite reaction, and enlarging a lower end of the hole using expansion force caused by the thermite reaction; and a curing step of curing the grouting material filled in the hole.
摘要翻译：提供了一种加强地面的方法。加固地面的方法包括：向下穿刺地面的穿孔步骤，其中构造有结构以形成孔; 将注浆材料填充到孔中的孔填充步骤; 将能量传递到由金属氧化物和金属粉末形成的金属混合物引起铝热反应的孔扩大步骤，并且利用由铝热反应引起的膨胀力扩大孔的下端; 以及固化填充在孔中的灌浆材料的固化步骤。

5. 发明申请

WO2008038969A1 THREE-DIMENSIONAL MEASUREMENT SYSTEM AND RESCALING METHOD USING INDOOR GPS 审中-公开
标题翻译：三维测量系统和使用室内GPS的重建方法
公开(公告)号：WO2008038969A1
公开(公告)日：2008-04-03
申请号：PCT/KR2007/004659
申请日：2007-09-21
申请人： SAMSUNG HEAVY IND. CO., LTD. , SONG, Se-Hwan , CHUNG, Seong-Youb , KIM, Sung-Han , PARK, Jin-Hyung , PARK, Young-Jun , KIM, Jae-Hoon
发明人： SONG, Se-Hwan , CHUNG, Seong-Youb , KIM, Sung-Han , PARK, Jin-Hyung , PARK, Young-Jun , KIM, Jae-Hoon
IPC分类号： G01C3/00
CPC分类号： G01C3/00 , G01B11/14 , G01S1/70
摘要： A three-dimensional measurement system using an IGPS includes a rescale bar having linear scales thereon, a linear encoder for measuring an absolute length within which the linear encoder moves on the rescale bar, a plurality of optical transmitters that radiates pan beams, and a vector bar having one end attached to the linear encoder, and having a receiver to detect the pan beams radiated from the optical transmitters, the vector bar acquiring coordinates of two points where the vector bar moves by using the receiver, and measuring a relative length from the coordinates. A ratio between the absolute length and the relative length is applied in rescaling an actual distance between two positions to be measured.
摘要翻译：使用IGPS的三维测量系统包括其上具有线性刻度的重定标杆，用于测量线性编码器在重定标杆上移动的绝对长度的线性编码器，辐射泛光束的多个光发射器，以及矢量杆，其一端连接到线性编码器，并具有用于检测从光学发射器辐射的摇摄光束的接收器，矢量条获取通过使用接收器移动矢量条的两个点的坐标，以及测量从坐标。绝对长度和相对长度之间的比率应用于两个测量位置之间的实际距离的重新缩放。

6. 发明申请

WO2004085626A1 MICROBIAL MATERIALS FOR DEGRADATION OF OILS AND TOXIC CHEMICALS 审中-公开
标题翻译：用于降解油和有毒化学物质的微生物材料
公开(公告)号：WO2004085626A1
公开(公告)日：2004-10-07
申请号：PCT/KR2004/000671
申请日：2004-03-25
申请人： YUM, Kyu-Jin , PARK, Young-Jun
发明人： YUM, Kyu-Jin , PARK, Young-Jun
IPC分类号： C12N1/16
CPC分类号： C12R1/645 , A62D2101/20 , B09C1/105 , C12N1/26
摘要： Provided is microbial materials for degradation of oils and toxic chemicals. The microbial material includes a mixture comprising a microorganism and culture filtrate capable of degrading oil and toxic chemicals being at least one selected from the group consisting of Trichosporon loubieri Y1-A of deposit No. KCTC 18079P, Trichosporon cutaneum, and white-rot fungi living upon the surface of wood, lipophilic powder being at least one selected from the group consisting of natural wax, synthetic wax, beeswax and waste candle, and a microbial nutrient. The microbial material can efficiently, rapidly degrade contaminants that are unreadily degradable, by increasing a contact area with the microorganism capable of degrading the unreadily degradable contaminants.
摘要翻译：提供用于降解油和有毒化学物质的微生物材料。微生物材料包括含有微生物和能够降解油的培养滤液和有毒化学物质的混合物，其为选自由沉积物编号KCTC 18079P，Trichosporon cutaneum和白腐真菌生活的Trichosporon loubieri Y1-A组成的组中的至少一种在木材表面上，亲油性粉末是选自天然蜡，合成蜡，蜂蜡和废蜡烛中的至少一种，以及微生物营养物质。通过增加与能够降解不可降解的污染物的微生物的接触面积，微生物物质可以有效地，快速地降解不可降解的污染物。

7. 发明申请

WO2009084849A2 CHROME-FREE COATING COMPOSITIONS FOR SURFACE-TREATING STEEL SHEET INCLUDING CARBON NANOTUBE, METHODS FOR SURFACE-TREATING STEEL SHEET AND SURFACE-TREATED STEEL SHEETS USING THE SAME 审中-公开
标题翻译：用于表面处理钢板的无铬涂层组合物，包括碳纳米管，表面处理钢板和使用其的表面处理钢板的方法
公开(公告)号：WO2009084849A2
公开(公告)日：2009-07-09
申请号：PCT/KR2008/007625
申请日：2008-12-23
申请人： POSCO , DPI HOLDINGS CO., LTD. , PARK, Young-Jun , KIM, Gab-Yong , CHEONG, Hoon
发明人： PARK, Young-Jun , KIM, Gab-Yong , CHEONG, Hoon
IPC分类号： C23C22/00 , C23C2/06
CPC分类号： C23C2/26 , C08K3/041 , C09D5/084 , C09D5/24 , C09D7/70 , C09D123/0869 , C09D163/00 , C09D171/00 , Y10T428/273 , C08L33/12 , C08L63/00 , C08L65/02 , C08L29/04
摘要： There are provided a chrome-free coating composition for surface-treating a hot-dip galvanized steel sheet including carbon nanotube that is distributed in a water-dispersible urethane resin, and a surface-treated steel sheet using the same. The chrome-free coating composition for surface- treating a hot-dip galvanized steel sheet that include carbon nanotube and has excellent electric conductivity, comprising, based on the total solid weight of the composition: (a) 40 to 60 parts by weight of a water-soluble or water-borne organic resin; (b) 20 to 40 parts by weight of an inorganic metallic sol; (c) 2 to 5 parts by weight of a carbon nanotube paste including carbon nanotube (CNT); (d) 2 to 5 parts by weight of a metal oxide/phosphate-based anti-corrosion agent; (e) 5 to 15 parts by weight of an organic metal complex; (f) 3 to 7 parts by weight of a carbodimide crosslinking agent, and (g) the balance of water, ethanol or a mixture thereof. The steel sheet surface-treated with the composition may be useful to secure the corrosion resistance without including a chrome component and show its electric conductivity even when the coating composition is used at a coating amount of 1000 mg/m 2 or more.
摘要翻译：提供了一种用于表面处理包含分散在水分散性聚氨酯树脂中的碳纳米管的热镀锌钢板和使用其的表面处理钢板的无铬涂料组合物。用于表面处理包括碳纳米管并且具有优异导电性的热浸镀锌钢板的无铬涂料组合物，包含基于组合物的总固体重量：（a）40至60重量份的水溶性或水性有机树脂; （b）20〜40重量份的无机金属溶胶; （c）2〜5重量份的包含碳纳米管（CNT）的碳纳米管膏; （d）2〜5重量份的金属氧化物/磷酸盐系防腐蚀剂; （e）5〜15重量份的有机金属络合物; （f）3-7重量份的碳二亚胺交联剂，和（g）余量的水，乙醇或其混合物。用组合物进行表面处理的钢板可以用于确保耐腐蚀性而不包括铬组分，并且即使当涂料组合物以1000mg / m 2或更多的涂布量使用时也显示其导电性。

8. 发明申请

WO2008035952A1 GLOBAL COORDINATE CREATION METHOD FOR PRECISION MEASUREMENT OF HOLLOW FRAME 审中-公开
标题翻译：用于中空框架精密测量的全局坐标创建方法
公开(公告)号：WO2008035952A1
公开(公告)日：2008-03-27
申请号：PCT/KR2007/004664
申请日：2007-09-21
申请人： SAMSUNG HEAVY IND. CO., LTD. , CHUNG, Seong-Youb , KIM, Sung-Han , SONG, Se-Hwan , PARK, Young-Jun , KIM, Jae-Hoon
发明人： CHUNG, Seong-Youb , KIM, Sung-Han , SONG, Se-Hwan , PARK, Young-Jun , KIM, Jae-Hoon
IPC分类号： G01S5/14
CPC分类号： G01S19/11 , G01C15/00
摘要： A method of creating a global coordinate of a polyhedral hollow frame includes a first step of providing a plurality of transmitters on a reference surface in the hollow frame, providing a plurality of reference sensors to create the coordinate of the reference surface, and creating a local coordinate frame of the reference surface on the basis of the positional coordinates measured by the reference sensors; a second step of providing reference sensors at common points of a first vertical surface neighboring to the reference surface to measure and store the coordinates of the common points; a third step of providing a plurality of transmitters and reference sensors on the first vertical surface neighboring to the reference surface to create a local coordinate frame of the first vertical surface; a fourth step of transforming the local coordinate frames created at the first and the third steps into a global coordinate frame using the coordinates of the common points measured at the second step; a fifth step of repeatedly performing the second step to the fourth step on remaining vertical surfaces of the polyhedral hollow frame to transform the respective local coordinate frames into a unified global coordinate frame; a sixth step of providing transmitters on an upper surface neighboring to each vertical surface to obtain the relationship between the global coordinate frame and a local coordinate frame of the upper surface using the coordinates of the common point; and a seventh step of creating and applying a global coordinate frame using the relationship obtained at the sixth step.
摘要翻译：创建多面体中空框架的全局坐标的方法包括：第一步骤，在中空框架的参考表面上提供多个发射器，提供多个参考传感器以产生参考表面的坐标，以及创建局部基于由参考传感器测量的位置坐标，参考表面的坐标系; 在与参考表面相邻的第一垂直表面的公共点处提供参考传感器以测量和存储公共点的坐标的第二步骤; 第三步骤，在与参考表面相邻的第一垂直表面上设置多个发射器和参考传感器，以产生第一垂直表面的局部坐标系; 使用在第二步骤测量的公共点的坐标将在第一和第三步骤中创建的局部坐标系变换为全局坐标系的第四步骤; 在所述多面体中空框架的剩余垂直表面上反复进行第二步骤至第四步骤的第五步骤，以将各个局部坐标系变换为统一的全局坐标系; 在与每个垂直表面相邻的上表面上提供发射器以使用公共点的坐标获得全局坐标系和上表面的局部坐标系之间的关系的第六步骤; 以及使用在第六步骤中获得的关系创建和应用全局坐标系的第七步骤。

9. 发明申请

WO2007064172A1 STEEL SHEET FOR HOT PRESS FORMING HAVING EXCELLENT HEAT TREATMENT AND IMPACT PROPERTY, HOT PRESS PARTS MADE OF IT AND THE METHOD FOR MANUFACTURING THEREOF 审中-公开
标题翻译：用于具有优良热处理和冲击性能的热压成型钢板，其热压件及其制造方法
公开(公告)号：WO2007064172A1
公开(公告)日：2007-06-07
申请号：PCT/KR2006/005155
申请日：2006-12-01
申请人： POSCO , OH, Jin-Keun , BAE, Dae-Chul , KIM, Seong-Ju , CHIN, Kwang-Geun , LEE, Jae-Ryung , PARK, Young-Jun
发明人： OH, Jin-Keun , BAE, Dae-Chul , KIM, Seong-Ju , CHIN, Kwang-Geun , LEE, Jae-Ryung , PARK, Young-Jun
IPC分类号： C22C38/04 , C22C38/00
CPC分类号： C22C38/02 , C22C38/001 , C22C38/04 , C22C38/06 , Y10T428/12 , Y10T428/12972
摘要： Disclosed is a steel sheet that exhibits an ultra-high strength after hot press forming followed by rapid cooling, and an enhanced yield strength after painting. The steel sheet has a composition comprising 0.1% to 0.5% by weight of C, 0.01% to 1.0% by weight of Si, 0.5% to 4.0% by weight of Mn, 0.1 % by weight or less of P, 0.03% by weight or less of S, 0.1 % by weight of soluble Al, 0.01% to 0.1% by weight of N, 0.3% by weight or less of W, and the balance Fe and other inevitable impurities. Further disclosed are a hot-pressed part made of the steel sheet and a method for manufacturing the hot-pressed part. The hot-pressed part achieves a high increment in yield strength after heat treatment for painting while ensuring an ultra-high tensile strength. Furthermore, the hot-pressed part exhibits superior adhesion to a coatinglayer, good surface appearance and improved corrosion resistance after painting.
摘要翻译：公开了一种在热压成型后快速冷却时具有超高强度的钢板，涂装后的屈服强度提高。该钢板具有0.1〜0.5重量％的C，0.01〜1.0重量％的Si，0.5〜4.0重量％的Mn，0.1重量％以下的P，0.03重量％或更少的S，0.1重量％的可溶性Al，0.01〜0.1重量％的N，0.3重量％以下的W，余量为Fe等不可避免的杂质。进一步公开了由钢板制成的热压部件和制造热压部件的方法。热压部件在确保超高抗拉强度的同时，在涂装热处理后的屈服强度增加很大。此外，热压部件对涂布层具有优异的粘附性，良好的表面外观和改善的涂漆后的耐腐蚀性。

10. 发明申请

WO2007024055A1 SURFACE MODIFIED INORGANIC MATERIAL AND PRODUCING METHOD THEREOF 审中-公开
标题翻译：表面改性无机材料及其制备方法
公开(公告)号：WO2007024055A1
公开(公告)日：2007-03-01
申请号：PCT/KR2006/001819
申请日：2006-05-16
申请人： INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY , JUN, Chul-Ho , YEON, Ye-Lim , LEE, Ji-Sung , PARK, Young-Jun
发明人： JUN, Chul-Ho , YEON, Ye-Lim , LEE, Ji-Sung , PARK, Young-Jun
IPC分类号： C03C17/30
CPC分类号： C03C17/42 , C03C17/009 , C08F292/00 , C08K3/36
摘要： This invention relates to a surface-modified inorganic material and a preparation method thereof . More particularly, the invention provides a surface- modified inorganic material which is obtained by allowing an organosilane compound having allyl or an allyl derivative to react with an inorganic material, particularly solid silica or ITO glass, in the presence of an acid and an organic solvent, so as to introduce an organic group into the inorganic material even at room temperature, as well as a preparation method thereof . The invention can effectively introduce the organic group into the inorganic material even at room temperature, and thus is very effective in introducing compounds having a thermally sensitive functional group, for example, natural compounds or proteins. Also, the invention makes it possible to introduce various organic groups into an inorganic material and to separate and purify organic molecule-bonded organosilane compounds using a silica gel column so as to effectively bond them to inorganic materials. Accordingly, the invention is very useful in the chemical industry.
摘要翻译：本发明涉及一种表面改性无机材料及其制备方法。更具体地说，本发明提供了一种表面改性的无机材料，其通过使具有烯丙基或烯丙基衍生物的有机硅烷化合物与无机材料，特别是固体二氧化硅或ITO玻璃在酸和有机溶剂的存在下反应而获得，以便即使在室温下也将有机基团引入到无机材料中，以及其制备方法。本发明即使在室温下也可以有机地将有机基团引入到无机材料中，因此在引入具有热敏性官能团的化合物例如天然化合物或蛋白质方面非常有效。此外，本发明使得可以将各种有机基团引入无机材料中，并且使用硅胶柱分离和纯化有机分子键合的有机硅烷化合物，以便有效地将它们结合到无机材料上。因此，本发明在化学工业中非常有用。

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