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1. 发明申请

WO02089880A8 INHALERS 审中-公开
标题翻译：吸入器
公开(公告)号：WO02089880A8
公开(公告)日：2003-04-03
申请号：PCT/EP0205186
申请日：2002-05-10
申请人： VECTURA DELIVERY DEVICES LTD , EASON STEPHEN WILLIAM , HARMER QUENTIN JOHN , SARKAR MATTHEW NEIL , PINON JOHN , DUNKLEY MICHAEL JOHN , CLARKE ROGER WILLIAM , HILL STEPHEN HENRY
发明人： EASON STEPHEN WILLIAM , HARMER QUENTIN JOHN , SARKAR MATTHEW NEIL , PINON JOHN , DUNKLEY MICHAEL JOHN , CLARKE ROGER WILLIAM , HILL STEPHEN HENRY
IPC分类号： A61M11/00 , A61M11/06 , A61M13/00 , A61M15/00
CPC分类号： A61M15/0028 , A61M11/002 , A61M11/06 , A61M15/0086 , A61M15/0091 , A61M2202/064 , A61M2205/073 , A61M2206/16

2. 发明申请

WO2009092434A3 INHALER 审中-公开
公开(公告)号：WO2009092434A3
公开(公告)日：2009-11-05
申请号：PCT/EP2008011126
申请日：2008-12-29
申请人： BOEHRINGER INGELHEIM INT , VECTURA DELIVERY DEVICES LTD , WACHTEL HERBERT , HARMER QUENTIN JOHN , SARKAR MATTHEW NEIL , MILIVOJEVIC IVAN
发明人： WACHTEL HERBERT , HARMER QUENTIN JOHN , SARKAR MATTHEW NEIL , MILIVOJEVIC IVAN
IPC分类号： A61M15/00
CPC分类号： A61M15/0005 , A61M11/002 , A61M15/0008 , A61M15/0026 , A61M15/0045 , A61M15/0051 , A61M15/0055 , A61M15/0058 , A61M15/0085 , A61M15/009 , A61M2202/064 , A61M2206/16
摘要： A passive inhaler (1) for delivery of a powder-form inhalation formulation from a blister strip (2) with a plurality of blister pockets (3) is proposed. The inhaler comprises an impaction element (31) onto which the air stream can impact together with entrained inhalation formulation for better deagglomeration. Alternatively, the inhaler comprises an oscillating and/or vibrating device (35) for better de- agglomeration of the inhalation formulation. Alternatively or additionally, the inhaler comprises one or two mixing means for generating swirls, preferably with opposite rotation directions.
摘要翻译：提出了一种用于从具有多个泡罩袋（3）的泡罩条（2）输送粉末形式的吸入制剂的被动吸入器（1）。吸入器包括冲击元件（31），空气流可以与夹带的吸入制剂一起冲击到冲击元件（31）上以便更好的解聚。或者，吸入器包括用于更好地吸收制剂团聚的振荡和/或振动装置（35）。或者或另外，吸入器包括用于产生涡流的一个或两个混合装置，优选地具有相反的旋转方向。

3. 发明申请

WO2009092551A3 INHALER 审中-公开
公开(公告)号：WO2009092551A3
公开(公告)日：2009-10-01
申请号：PCT/EP2009000294
申请日：2009-01-19
申请人： BOEHRINGER INGELHEIM INT , VECTURA DELIVERY DEVICES LTD , EASON STEPHEN WILLIAM , SARKAR MATTHEW NEIL , GIBBINS GRAHAM ROGER , THOEMMES RALF , FRENTZEL-BEYME JESSICA , BESSELER JENS , VON BRUNN TIMO
发明人： EASON STEPHEN WILLIAM , SARKAR MATTHEW NEIL , GIBBINS GRAHAM ROGER , THOEMMES RALF , FRENTZEL-BEYME JESSICA , BESSELER JENS , VON BRUNN TIMO
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A61M15/0026 , A61M15/0036 , A61M15/0041 , A61M15/0051 , A61M2202/064
摘要： An inhaler (1) for delivery of a powder-form inhalation formulation from a blister strip (2) with a plurality of blister pockets (3) is proposed. A flexible guiding element (20) receives the used blisters strip.
摘要翻译：提出了一种用于从具有多个泡罩袋（3）的泡罩带（2）输送粉末形式的吸入制剂的吸入器（1）。柔性引导元件（20）容纳所使用的泡罩带。

4. 发明申请

WO0207805A3 INHALERS 审中-公开
标题翻译：吸入器
公开(公告)号：WO0207805A3
公开(公告)日：2002-06-13
申请号：PCT/EP0108416
申请日：2001-07-20
申请人： CAMBRIDGE CONSULTANTS , EASON STEPHEN WILLIAM , HARMER QUENTIN JOHN , SARKAR MATTHEW NEIL
发明人： EASON STEPHEN WILLIAM , HARMER QUENTIN JOHN , SARKAR MATTHEW NEIL
IPC分类号： A61M11/00 , A61M15/00 , A61M15/02 , A61M16/00
CPC分类号： A61M15/02 , A61M11/002 , A61M15/002 , A61M15/0028 , A61M15/0036 , A61M15/0041 , A61M15/0086 , A61M16/0066 , A61M2202/064 , A61M2206/16
摘要： An inhaler for producing an inhalable aerosol of a powdered medicament comprises a cyclone (1) with a tangential air inlet (3) and an axial air outlet (4). The cyclone (1) aerosolises and retains an aerosol of powdered medicament in an airflow circulating between the inlet (3) and the outlet (4). The cyclone (1) has an exit port (2) which is open to atmosphere. When the aerosol is to be inhaled, the pressure in the cyclone (1) is increased by increasing the airflow to the inlet (3) which causes the aerosol to discharge through the exit port (2). The inhaler has the advantage that the rate of discharge of the aerosol can be controlled independently of the rate of airflow required to aerosolise the medicament.
摘要翻译：一种用于生产粉状药物的可吸入气溶胶的吸入器，包括具有切向空气入口（3）和轴向空气出口（4）的旋风分离器（1）。旋风器（1）在入口（3）和出口（4）之间循环的气流中雾化并保持粉末药物的气溶胶。旋风分离器（1）具有通向大气的出口（2）。当气雾被吸入时，旋风分离器（1）中的压力通过增加通向入口（3）的气流而增加，这导致气溶胶通过出口（2）排出。吸入器的优点在于，可以独立于雾化药物所需的气流速率来控制气溶胶的排出速率。

5. 发明申请

WO2004012801A8 POWDER INHALER 审中-公开
标题翻译：粉末吸入器
公开(公告)号：WO2004012801A8
公开(公告)日：2004-04-29
申请号：PCT/EP0308432
申请日：2003-07-30
申请人： CHIESI FARMA SPA , PINON JOHN , SHIRGAONKAR SAMEER , SMITH CHRISTOPHER JAMES , BURGE SIMON , MIDDLETON MAX WILLIAM , AHERN DAVID , SARKAR MATTHEW NEIL , ARLETT BEN , LYE EMMA LESLEY , SMITH SIMON
发明人： PINON JOHN , SHIRGAONKAR SAMEER , SMITH CHRISTOPHER JAMES , BURGE SIMON , MIDDLETON MAX WILLIAM , AHERN DAVID , SARKAR MATTHEW NEIL , ARLETT BEN , LYE EMMA LESLEY , SMITH SIMON
IPC分类号： A61M15/00 , G06M1/04 , G06M1/24
CPC分类号： A61M15/0065 , A61M15/0026 , A61M15/0075 , A61M2202/062 , A61M2202/064 , A61M2206/16 , G06M1/04 , G06M1/045 , G06M1/248
摘要： A powder inhaler comprises a container (7) for storing a powdered medicament, a metering member (15) having a dosing recess (18) to be filled with a dose of the powdered medicament, and a mouthpiece (3) being in communication with an inhalation channel (27) of the powder inhaler. Furthermore, the powder inhaler comprises a protective member (19) which is slidingly moveable on the metering member (15) between a closed position, in which it at least covers the dosing recess (18) of the metering member (15) if the metering member (15) is in an inhalation position, and an open position, in which it exposes the dosing recess (18) thereby enabling inhalation of the dose of the powdered medicament contained in the dosing recess (18). The protective member (19) is preferably coupled to an inhalation actuated mechanism (21-23) in such a manner that the inhalation actuated mechanism (21-23) moves the protective member (19) from its closed position to its open position only if there is an inhalation suction force exerted by a user which exceeds a predetermined level. This prevents the dose contained in the dosing recess (18) from falling out of the dosing recess, unless there is no inhalation process initiated by the user. Therefore, the powder inhaler can also be operated reliably upside down. Furthermore, a deagglomerator arrangement (cyclone), which may be incorporated in such a powder inhaler, is proposed which comprises a vortex chamber (73) having a diameter between 6 mm and 8 mm, preferably 8 mm.
摘要翻译：粉末吸入器包括用于储存粉末药物的容器（7），具有待填充剂量的粉末药物的计量凹部（18）的计量构件（15），以及与一个粉末吸入器的吸入通道（27）。此外，粉末吸入器包括保护构件（19），该保护构件可在计量构件（15）之间在关闭位置之间滑动运动，在闭合位置中，其至少覆盖计量构件（15）的计量凹部（18），如果计量构件（15）处于吸入位置，并且处于打开位置，在所述打开位置，所述打开位置暴露所述计量凹部（18），从而能够吸入所述剂量凹部（18）中所含的粉末状药物的剂量。保护构件（19）优选地以这样的方式联接到吸入致动机构（21-23），使得吸入致动机构（21-23）仅当保护构件（19）从其关闭位置移动到其打开位置时才移动存在超过预定水平的用户施加的吸入吸力。这防止剂量凹陷（18）中包含的剂量从剂量凹槽中脱落，除非由用户发起吸入过程。因此，粉末吸入器也可以可靠地上下颠倒地操作。此外，提出了可以结合在这种粉末吸入器中的解聚器装置（旋风分离器），其包括直径在6mm和8mm之间，优选为8mm的涡流室（73）。

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