会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 2. 发明申请
    • RECURRENT FUSION GENES IN HUMAN CANCERS
    • 人类癌症中的融合基因
    • WO2015175732A2
    • 2015-11-19
    • PCT/US2015/030677
    • 2015-05-13
    • THE UNIVERSITY OF CHICAGO
    • WHITE, Kevin, P.BANDLAMUDI, Chaitanya
    • G11C27/02H03M1/12
    • C12Q1/6886C12Q2600/106C12Q2600/118C12Q2600/158
    • Fusion transcripts are provided herein. In exemplary embodiments, the fusion transcript is encoded by a nucleic acid molecule comprising a general structure A-B, wherein structure A is a portion of a gene listed in Column A of Table 1 and structure B is a portion of a gene listed in Column B of Table 1, wherein the gene listed in Column A and the gene listed in Column B are listed in the same row of Table 1, wherein structure B is located immediately 3' to structure A. Polypeptides encoded by the fusion transcript, nucleic acid molecules encoding the fusion transcript, and nucleic acid molecules comprising the reverse complement sequence of the fusion transcript, are additionally provided. Related expression vectors, host cells, binding agents, kits, and methods of using the same are further provided herein.
    • 本文提供了融合转录本。 在示例性实施方案中,融合转录物由包含一般结构AB的核酸分子编码,其中结构A是表1列A中所列基因的一部分,结构B是B列中列出的基因的一部分 表1,其中列A中列出的基因和列B中列出的基因列于表1的相同行,其中结构B立即位于结构A 3'处。由融合转录物编码的多肽,编码的核酸分子 融合转录物和包含融合转录物的反向互补序列的核酸分子。 本文进一步提供相关表达载体,宿主细胞,结合剂,试剂盒及其使用方法。