专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2002085376A2 A METHOD FOR DECREASING SUPEROXIDE ANIONS PRODUCTION AND TREATMENT OF OXIDATIVE STRESS 审中-公开
标题翻译：一种减少超氧化物阴离子生产和处理氧化应力的方法
公开(公告)号：WO2002085376A2
公开(公告)日：2002-10-31
申请号：PCT/CA2002/000568
申请日：2002-04-19
申请人： UNIVERSITE DE MONTREAL , DE CHAMPLAIN, Jacques , WU, Rong , EL MIDAOUI, Adil
发明人： DE CHAMPLAIN, Jacques , WU, Rong , EL MIDAOUI, Adil
IPC分类号： A61K31/60
CPC分类号： A61K31/616 , A61K31/60
摘要： The present invention relates to a new method for reducing vascular, cardiac and colonic tissue O 2 - generation by lowering the NAD(P)H oxidase activity of these tissues in normal and hypertensive subjects using ASA, nimesulide and indomethacin. Although ASA did not show any acute effect in vitro , chronic oral treatment or chronic incubation with ASA significantly lowered the O 2 - basal or NAD(P)H activated production in aorta and smooth muscle cells from normotensive and hypertensive rats. These effects were dose-dependent and needed more than 3 days to onset in vivo condition. ASA treatment significantly improved the impaired aortic relaxation response to acetylcholine in SHR and significantly attenuated the age-dependent development of hypertension in young SHR. In another model of hypertension and insulin resistance induced by high glucose feeding, which was also found to be associated with a higher production of superoxide anion in tissues from the cardiovascular system, chronic ASA treatment was found to prevent simultaneously the development of hypertension, insulin resistance and the production of superoxide anion. Finally, in another hypertension model induced by the chronic administration of angiotensin II which has the property to activate NAD(P)H oxidase and to enhance the superoxide production in vessels, the concomitant treatment with ASA was also found to simultaneously prevent the development of hypertension and the enhanced superoxide anion production.
摘要翻译：本发明涉及一种通过使用ASA，尼美舒利和吲哚美辛降低正常和高血压受试者中这些组织的NAD（P）H氧化酶活性来减少血管，心脏和结肠组织O 2代的新方法。尽管ASA在体外没有显示出任何急性效应，但慢性口服治疗或与ASA的慢性温育显着降低了主动脉和平滑肌细胞从血压正常的O2（P）H激活的产生。和高血压大鼠。这些作用是剂量依赖性的，并且需要在体内条件发生3天以上。 ASA治疗显着改善SHR中乙酰胆碱受损的主动脉松弛反应，并显着减轻年轻SHR中高血压的年龄依赖性发展。在高葡萄糖喂养诱导的高血压和胰岛素抵抗的另一模型中，也发现与心血管系统组织中超氧化物阴离子的产生量相关，慢性ASA治疗可以预防同时发生高血压，胰岛素抵抗并产生超氧阴离子。最后，在慢性给予血管紧张素II诱导的高血压模型中，其具有激活NAD（P）H氧化酶的性质并增强血管中的超氧化物产生，同时也发现ASA伴随治疗同时预防高血压发展并增强超氧阴离子的生成。

2. 发明申请

WO2003106466A2 N-HALAMINE SILOXANES FOR USE IN BIOCIDAL COATINGS AND MATERIALS 审中-公开
标题翻译：用于生物涂料和材料的N-山梨糖醇硅氧烷
公开(公告)号：WO2003106466A2
公开(公告)日：2003-12-24
申请号：PCT/US2003/018883
申请日：2003-06-12
申请人： AUBURN UNIVERSITY , VANSON HALOSOURCE, INC. , WORLEY, Shelby, D. , CHEN, Yongjun , WANG, Jia-Wang , WU, Rong , LI, Yanjun
发明人： WORLEY, Shelby, D. , CHEN, Yongjun , WANG, Jia-Wang , WU, Rong , LI, Yanjun
IPC分类号： C07F7/18
CPC分类号： C07F7/1836 , Y10T428/31663
摘要： Heterocyclic and acyclic silane monomers and siloxane polymers, and their halogenated derivatives, are provided for the purpose of functionalizing surfaces or materials so as to render them biocidal upon exposure to oxidative halogen solutions.The biocidal function can be imparted either before or after bonding or adhesion to the surface or material. The biocidal surfaces and materials can then be used to inactivate pathogenic microorganisms such as bacteria, fungi, and yeasts, as well as virus particles, which can cause infectious diseases, and those microorganisms which cause noxious odors and unpleasant coloring such as mildew. Examples of surfaces and materials which can be rendered biocidal in this invention include, but are not limited to, cellulose, chitin, chitosan, synthetic fibers, glass, ceramics, plastics, rubber, cement grout, latex caulk, porcelain, acrylic films, vinyl, polyurethanes, silicon tubing, marble, metals, metal oxides, and silica.
摘要翻译：提供杂环和非环状硅烷单体和硅氧烷聚合物及其卤化衍生物用于官能化表面或材料的目的，以便在暴露于氧化卤素溶液时使其成为杀生物剂。杀生物功能可以在粘合或粘附之前或之后赋予到表面或材料。然后杀生物表面和材料可用于灭活病原微生物如细菌，真菌和酵母，以及可能引起传染病的病毒颗粒，以及引起有害气味和不愉快着色如霉菌的微生物。在本发明中可呈现杀生物剂的表面和材料的实例包括但不限于纤维素，壳多糖，壳聚糖，合成纤维，玻璃，陶瓷，塑料，橡胶，水泥浆，乳胶填料，瓷，丙烯酸膜，乙烯基，聚氨酯，硅管，大理石，金属，金属氧化物和二氧化硅。

3. 发明申请

WO2003106466A3 HETEROCYCLIC HALAMINE-SUBSTITUTED SILOXANES FOR USE IN BIOCIDAL COATINGS AND MATERIALS 审中-公开
公开(公告)号：WO2003106466A3
公开(公告)日：2003-12-24
申请号：PCT/US2003/018883
申请日：2003-06-12
申请人： AUBURN UNIVERSITY , VANSON HALOSOURCE, INC. , WORLEY, Shelby, D. , CHEN, Yongjun , WANG, Jia-Wang , WU, Rong , LI, Yanjun
发明人： WORLEY, Shelby, D. , CHEN, Yongjun , WANG, Jia-Wang , WU, Rong , LI, Yanjun
IPC分类号： C07F7/18
摘要： Siloxane monomers and polymers functionalized by certain N-halogenated heterocyclic moieties are provided for the purpose of functionalizing surfaces or materials so as to render them biocidal upon exposure to oxidative halogen solutions. The biocidal function can be imparted either before or after bonding or adhesion to the surface or material. The biocidal surfaces and materials can then be used to inactivate pathogenic microorganisms such as bacteria, fungi, and yeasts, as well as virus particles, which can cause infectious diseases, and those microorganisms which cause noxious odors and unpleasant coloring such as mildew. Examples of surfaces and materials which can be rendered biocidal in this invention include, but are not limited to, cellulose, chitin, chitosan, synthetic fibers, glass, ceramics, plastics, rubber, cement grout, latex caulk, porcelain, acrylic films, vinyl, polyurethanes, silicon tubing, marble, metals, metal oxides, and silica.

4. 发明申请

WO2011147079A1 EXPOSED LENS RETROREFLECTIVE ARTICLE 审中-公开
标题翻译：暴露镜片回归文章
公开(公告)号：WO2011147079A1
公开(公告)日：2011-12-01
申请号：PCT/CN2010/073217
申请日：2010-05-25
申请人： 3M INNOVATIVE PROPERTIES COMPANY , HUANG, Ningyong , KLUNDT, Shane Michael , LI, Huijin , LUCAS, Loretta Lauren , RAY, Bradley Robert , WU, Rong
发明人： HUANG, Ningyong , KLUNDT, Shane Michael , LI, Huijin , LUCAS, Loretta Lauren , RAY, Bradley Robert , WU, Rong
IPC分类号： G02B5/12 , G02B5/128 , B32B5/16 , B44F1/00
CPC分类号： G02B5/13 , B05D5/063 , B44C1/1712 , B44F1/02 , G02B1/10 , G02B5/128
摘要： An exposed lens retroreflective article (10) includes a binder layer (14); a layer of spaced apart optical elements (12) that are partially embedded in the binder layer (14); a penetrated colored layer (18) that is located between the spaced apart optical elements (12); and a reflective layer (16) that is located functionally behind the layer of optical elements (12) and the penetrated colored layer (18).
摘要翻译：曝光透镜回射制品（10）包括粘合剂层（14）; 一层间隔开的光学元件（12），其被部分地嵌入所述粘合剂层（14）中; 位于间隔开的光学元件（12）之间的穿透着色层（18）; 以及位于功能上位于光学元件层（12）和穿透着色层（18）之后的反射层（16）。

5. 发明申请

WO2011143144A3 AN ELECTROMAGNETIC SHIELDING ADHESIVE TAPE 审中-公开
公开(公告)号：WO2011143144A3
公开(公告)日：2011-11-17
申请号：PCT/US2011/035817
申请日：2011-05-10
申请人： 3M INNOVATIVE PROPERTIES COMPANY , ZHANG, Wen Jie , WU, Rong
发明人： ZHANG, Wen Jie , WU, Rong
IPC分类号： C09J7/02 , B32B27/00 , H05K9/00
摘要： The invention provides an electromagnetic shielding adhesive tape, comprising: a resin film layer; and an electro-magnetic interference shielding layer with a sandwiched structure, which is laminated with the resin film layer and comprises: a first adhesive layer bonded to one side of the resin film layer; a second adhesive layer; and a conductive metal layer provided between the first adhesive layer and the second adhesive layer.

6. 发明申请

WO2006099567A2 BIOCIDAL N-HALAMINE EPOXIDES 审中-公开
标题翻译：生物碱N-硫杂环氧化物
公开(公告)号：WO2006099567A2
公开(公告)日：2006-09-21
申请号：PCT/US2006/009628
申请日：2006-03-10
申请人： AUBURN UNIVERSITY , WORLEY, S.D. , LIANG, Jie , CHEN, Yongjun , BROUGHTON, Royall, M. , WANG, Jia-wang , WU, Rong , CHO, Unchin , LEE, Jaewoong , BARNES, Kevin
发明人： WORLEY, S.D. , LIANG, Jie , CHEN, Yongjun , BROUGHTON, Royall, M. , WANG, Jia-wang , WU, Rong , CHO, Unchin , LEE, Jaewoong , BARNES, Kevin
IPC分类号： C11D7/26
CPC分类号： A01N65/00 , A01N35/02 , A01N43/50 , A01N43/90 , A01N59/00 , A61Q17/005 , C09D5/14 , C09D5/16 , A01N25/10 , A01N25/34
摘要： N-halaminehydantoinyl epoxide compounds which can be used for the construction of coatings and materials which can be rendered biocidal by exposure to halogen solutions either before or after curing the coating or material are disclosed. The biocidal coatings and materials can then be used to inactivate pathogenic microorganisms such as bacteria, fungi, and yeasts, as well as virus particles, which can cause infectious diseases, and those microorganisms which cause noxious odors and unpleasant coloring such as mildew. The coatings are compatible with a variety of substrates including, but not limited to, cellulose, chitin, chitosan, synthetic fibers, cement grout, latex caulk, acrylic films, polyurethanes, plastics and paints.
摘要翻译：公开了可用于构建涂料和材料的N-卤代乙酰乙酰基环氧化合物，其可以在固化涂层或材料之前或之后通过暴露于卤素溶液而具有杀菌作用。然后可以使用杀生物涂层和材料来灭活病原微生物，例如细菌，真菌和酵母，以及可能引起传染病的病毒颗粒，以及引起有害气味和不愉快着色如微生物的微生物。涂层与各种基材相容，包括但不限于纤维素，壳多糖，壳聚糖，合成纤维，水泥浆，乳胶填缝剂，丙烯酸膜，聚氨酯，塑料和油漆。

7. 发明申请

WO2005058814A3 BIOCIDAL SILOXANE COATING MATERIAL CONTAINING N-HALOGENATED AMINE AND AMIDE FUNCTIONAL GROUPS 审中-公开
公开(公告)号：WO2005058814A3
公开(公告)日：2005-06-30
申请号：PCT/US2004/038558
申请日：2004-11-17
申请人： AUBURN UNIVERSITY , WORLEY, Shelby, D. , CHEN, Yongjun , LIANG, Jie , WU, Rong , BARNES, Kevin , BROUGHTON, Royall, M , CHO, Unchin , LEE, Jaewoong
发明人： WORLEY, Shelby, D. , CHEN, Yongjun , LIANG, Jie , WU, Rong , BARNES, Kevin , BROUGHTON, Royall, M , CHO, Unchin , LEE, Jaewoong
IPC分类号： C07D401/02
摘要： N-halamine compounds which contain hindered amine and amide functional groups. Compounds include structure (TTDD); wherein X, X’, and X’’ independently are H, CI, or Br, wherein no more than two of X, X’, and X’’ are H and structure (I) wherein R, R’, and R’’ are independently alkyl groups containing (1) to (4) carbon atoms or hydrogen, and X and X’ are independently H, CI, or Br. Compositions comprising the compounds are also described. The compounds and/or compositions can be used, for example, for the purpose of constructing biocidal coatings and materials. The biocidal activity can inactivate pathogenic microorganisms such as bacteria, fungi, and yeasts, as well as, virus particles, which can cause infectious diseases, and those microorganisms which cause noxious odors and unpleasant coloring, such as mildew.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式