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1. 发明申请

WO2012131052A1 A PROGNOSTIC AND THERAPEUTIC SIGNATURE FOR MALIGNANT MELANOMA 审中-公开
标题翻译：恶性肿瘤的预防和治疗标志
公开(公告)号：WO2012131052A1
公开(公告)日：2012-10-04
申请号：PCT/EP2012/055827
申请日：2012-03-30
申请人： UNIVERSITÄT REGENSBURG , ETH ZURICH , UNIVERSITÄT ZÜRICH , MEYER, Stefanie , BOSSERHOFF, Anja , WILD, Peter , FUCHS, Thomas
发明人： MEYER, Stefanie , BOSSERHOFF, Anja , WILD, Peter , FUCHS, Thomas
IPC分类号： G01N33/574
CPC分类号： G01N33/5743 , G01N2800/52 , G01N2800/56
摘要： The present invention relates to a method of predicting the course of disease in a patient having a malignant melanoma, the method comprising determining in melanoma cells comprised in a sample obtained from said malignant melanoma the presence or amount of at least five biomarkers selected from the group comprising or consisting of MTAP, PTEN, Bax, Bcl-X, β-Catenin, CD20, Cox-2, CD49d and MLH1, wherein the absence or decreased amount of MTAP and β-Catenin and/or the presence or increased amount of PTEN, Bax, Bcl-X, CD20, Cox-2, CD49d and MLH1, is associated with a disadvantageous course of disease. The present invention further relates to a method of preparing a tailored pharmaceutical composition for a patient having a malignant melanoma, a kit for predicting the course of disease in a patient having a malignant melanoma, a kit for preparing a tailored pharmaceutical composition for a patient having a malignant melanoma as well as a pharmaceutical composition for use in treating or preventing malignant melanoma.
摘要翻译：本发明涉及一种预测具有恶性黑素瘤的患者疾病进程的方法，所述方法包括在从所述恶性黑素瘤获得的样品中包含的黑素瘤细胞中测定选自组中的至少5种生物标志物的存在或量由MTAP，PTEN，Bax，Bcl-X，β-连环蛋白，CD20，Cox-2，CD49d和MLH1组成或组成，其中不存在或减少量的MTAP和β-连环蛋白和/或存在或增加量的PTEN ，Bax，Bcl-X，CD20，Cox-2，CD49d和MLH1与疾病的不利过程相关。本发明还涉及制备用于具有恶性黑素瘤的患者的定制药物组合物的方法，用于预测具有恶性黑素瘤的患者的疾病进程的试剂盒，用于制备患者的定制药物组合物的试剂盒，恶性黑素瘤以及用于治疗或预防恶性黑素瘤的药物组合物。

2. 发明申请

WO2004031301A1 ACID RED 82 IN MISCHUNGEN 审中-公开
标题翻译：酸性红82在混合物中
公开(公告)号：WO2004031301A1
公开(公告)日：2004-04-15
申请号：PCT/EP2003/010210
申请日：2003-09-13
申请人： BAYER CHEMICALS AG , SOMMERMANN, Thomas , WILD, Peter
发明人： SOMMERMANN, Thomas , WILD, Peter
IPC分类号： C09B67/22
CPC分类号： C09D11/32 , C09B67/0036
摘要： Mischung, enthaltend die Farbstoffe C.I. Acid Red 82 (Formel IIb) und C.I. Acid Red 80 (Formel IIc).
摘要翻译：混合物，其包含染料C.I. 酸性红82（式Ⅱb）和C.I. 酸性红80（式IIc）中。

3. 发明申请

WO2009140767A1 MICRON-SCALE PRESSURE SENSORS AND USE THEREOF 审中-公开
标题翻译：微型压力传感器及其使用
公开(公告)号：WO2009140767A1
公开(公告)日：2009-11-26
申请号：PCT/CA2009/000701
申请日：2009-05-21
申请人： UNIVERSITY OF VICTORIA INNOVATION AND DEVELOPMENT CORPORATION , DENNISON, Christopher , WILD, Peter
发明人： DENNISON, Christopher , WILD, Peter
IPC分类号： G01D5/32 , G01L11/02
CPC分类号： G01L11/025 , G01D5/35303 , G01K11/3206 , G01L9/0007 , Y10T29/49002
摘要： A optical fibre sensing device for detecting physical parameters such as pressures, strains and temperatures. The sensing device comprises a probe housing therein an optical fibre. The distal end of the probe houses a distal portion of the optical fibre having a section provided with a fibre Bragg grating. The proximal end of the probe is mounted into a holder. The optical fibre is sealably mounted into the probe housing with a first seal overlaid the proximal portion of the optical fibre The seal may extend to about the proximal end of the optical fibre section with the Bragg grating. A second seal is overlaid the distal portion of the optical fibre and extends from the distal end of the probe to about the distal end of the optical fibre section with the Bragg grating. The proximal end of the probe is communicable with a fibre Bragg grating interrogation system.
摘要翻译：用于检测诸如压力，应变和温度的物理参数的光纤感测装置。感测装置包括在其中容纳光纤的探针。探头的远端容纳光纤的远端部分，其具有设置有光纤布拉格光栅的部分。探头的近端安装在支架上。光纤可密封地安装到探针外壳中，第一密封件覆盖在光纤的近端部分上。密封件可以用布拉格光栅延伸到光纤部分的近端。第二密封件覆盖在光纤的远端部分上，并从布拉格光栅从探头的远端延伸到光纤部分的远端。探头的近端可与光纤布拉格光栅询问系统通信。

4. 发明申请

WO2010086106A1 REDUCING SIGNALLING LOADS FROM A MOBILE NETWORK 审中-公开
标题翻译：从移动网络减少信号负载
公开(公告)号：WO2010086106A1
公开(公告)日：2010-08-05
申请号：PCT/EP2010/000308
申请日：2010-01-20
申请人： VODAFONE HOLDING GMBH , KULAKOV, Alexei , LU, Yang , WILD, Peter
发明人： KULAKOV, Alexei , LU, Yang , WILD, Peter
IPC分类号： H04W48/18
CPC分类号： H04W28/06 , H04W52/0209 , H04W68/00 , H04W88/06 , Y02D70/1222 , Y02D70/1224 , Y02D70/1226 , Y02D70/1242 , Y02D70/1262
摘要： The present invention relates to a method A method for reducing signalling loads from a mobile device (UE) to a mobile telecommunications network system comprising a first radio access technology (GSM/UMTS) having a first radio access network and a first network core operable to page a mobile device (UE) via at least one element of the first radio access technology and a second radio access technology (SAE/LTE) having a second radio access network and a second network core operable to page a mobile device (UE) via at least one element of the second radio access technology due to intersystem changes, wherein the mobile device (UE) stores at least one first EPS bearer context and/or at least one first PDP context at the time when an idle or inactive state signalling reduction (idle mode signalling reduction (ISR)) is activated at the mobile device (UE) and the respective network and for supporting mobile services uses the stored at least one first EPS bearer context and/or at least one first PDP context or at least one second EPS bearer context and/or at least one second PDP context, which at least one second EPS bearer context and/or at least one second PDP context is activated between the mobile device (UE) and the respective network after the activation of the idle or inactive state signalling reduction (idle mode signalling reduction (ISR)). Furthermore, the invention relates to a mobile device to be operated in a in a mobile telecommunication system including a first radio access technology having a first radio access network and a first network core operable to page a mobile device via at least one element of the first radio access technology and a second radio access technology having a second radio access network and a second network core operable to page a mobile device via at least one element of the second radio access technology, which mobile device is designed and/or adapted to at least partially carry out a method according to the invention.
摘要翻译：本发明涉及一种用于减少从移动设备（UE）到移动电信网络系统的信令负载的方法，该方法包括具有第一无线电接入网络的第一无线电接入技术（GSM / UMTS）和可操作为经由第一无线电接入技术的至少一个元件寻呼移动设备（UE）和具有第二无线电接入网络和第二网络核心的第二无线接入技术（SAE / LTE），其可操作以经由由于系统间变化，第二无线电接入技术的至少一个元件，其中移动设备（UE）在空闲或非活动状态信令减少时存储至少一个第一EPS承载上下文和/或至少一个第一PDP上下文（空闲模式信令减少（ISR））在移动设备（UE）处被激活，并且相应的网络并且用于支持移动业务使用所存储的至少一个第一EPS承载上下文和/或至少一个f 第一PDP上下文或至少一个第二EPS承载上下文和/或至少一个第二PDP上下文，所述至少一个第二EPS承载上下文和/或至少一个第二PDP上下文在所述移动设备（UE）和相应的网络激活后的空闲或非活动状态信令减少（空闲模式信令减少（ISR））。此外，本发明涉及要在移动电信系统中操作的移动设备，包括具有第一无线电接入网络的第一无线电接入技术和可操作以经由第一无线电接入网络中的至少一个元素来寻呼移动设备的第一网络核心无线电接入技术和具有第二无线电接入网络和第二网络核心的第二无线电接入技术，所述第二无线电接入网络和第二网络核心可操作以经由所述第二无线电接入技术的至少一个元件寻呼移动设备，所述移动设备被设计和/或适于至少部分地执行根据本发明的方法。

5. 发明申请

WO2008020235A2 MOBILE SWITCHING CENTRE HANDOVER 审中-公开
标题翻译：移动切换中心切换
公开(公告)号：WO2008020235A2
公开(公告)日：2008-02-21
申请号：PCT/GB2007/003165
申请日：2007-08-20
申请人： VODAFONE GROUP PLC , RUSSELL, Nick , WILD, Peter
发明人： RUSSELL, Nick , WILD, Peter
IPC分类号： H04Q7/38
CPC分类号： H04W8/06 , H04W4/16 , H04W8/18 , H04W36/12 , H04W88/14
摘要： An apparatus for retaining contact data for a subscriber to a mobile communication network comprising means for storing contact data for subscribers to a mobile network located within an area served by a mobile switching centre, means for receiving confirmation at the mobile switching centre (MSC) that a subscriber has left the area, means for updating the contact data to identify that the subscriber has left the area and means for retaining at least part of the contact data, the retained part of the contact data containing call forwarding details for the subscriber.
摘要翻译：一种用于将订户的联系人数据保留到移动通信网络的装置，包括用于存储用户定位到由移动交换中心服务的区域内的移动网络的联系人数据的装置，用于在移动交换中心（MSC）接收确认的装置用户离开该区域，用于更新联系人数据以识别用户已经离开该区域的装置以及用于保留至少部分联系人数据的装置，该保留部分的联系人数据包含用户的呼叫转移细节。

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