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    • 1. 发明申请
    • DELAYED RELEASE OF FLUIDS
    • 延迟释放流体
    • WO0155293A3
    • 2001-12-27
    • PCT/GB0100274
    • 2001-01-25
    • UNIV MANCHESTERCLARKE DAVID JOHNSMITH ANDREW
    • CLARKE DAVID JOHNSMITH ANDREW
    • C12M1/26B01L3/00C12M1/28C12N1/00
    • C12M23/34
    • A method of effecting delayed release of a fluid (19) comprises providing the fluid in a vessel (12) having a discharge aperture (14) provided with a polymeric barrier (15) to fluid release. The barrier (15) is caused to degrade to provide for failure of the barrier and discharge of the fluid. The liquid to be discharged may be an aqueous medium and the barrier (15) may be of a polymeric material capable of forming in the presence of the aqueous medium a gel that will dissolve therein so as to cause failure of the barrier. The polymeric material may be a cellulose ether. The fluid may, for example, comprise a culture of microorganisms which are subjected to pre-enrichment in the vessel for a predetermined period of time prior to failulre of the barrier (15) and discharge of the culture into, for example, a selective medium.
    • 实现流体(19)的延迟释放的方法包括在具有排放孔(14)的容器(12)中提供流体,所述排放孔(14)设置有聚合物屏障(15)以流体释放。 导致屏障(15)劣化以提供障碍物和流体的排出。 要排出的液体可以是水性介质,并且阻挡层(15)可以是能够在水介质存在下形成的聚合物材料,其将溶解在其中以使得屏障失效的凝胶。 聚合物材料可以是纤维素醚。 流体可以例如包括微生物培养物,其在阻隔物(15)失效之前在容器中进行预富集预定的时间并将培养物排放到例如选择性培养基 。