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1. 发明申请

WO2013189965A2 HAIR COLOURING COMPOSITION 审中-公开
标题翻译：头发着色组合物
公开(公告)号：WO2013189965A2
公开(公告)日：2013-12-27
申请号：PCT/EP2013/062700
申请日：2013-06-19
申请人： UNILEVER PLC , UNILEVER N.V. , CONOPCO, INC., d/b/a UNILEVER
发明人： BHOGAL, Ranjit, Kaur , CASEY, John , GANGULI, Shovan , HUNTER, Karl, John , KOEK, Jean, Hypolites , REDFERN, Sally, Pamela
IPC分类号： A61K8/00
CPC分类号： A61K8/22 , A61K8/498 , A61K8/97 , A61K8/9706 , A61K2800/4322 , A61K2800/4324 , A61Q5/065 , A61Q5/10
摘要： Hair colourant formulations fall into three main categories designated permanent, semi-permanent and temporary. Permanent hair colourant formulations are oxidative dye systems and generally contain paraphenylene diamine (PPD) and resorcinol, both of which have been shown to cause sensitisation and mutagenicity. Furthermore, severe oxidising conditions are required which in themselves cause skin irritation and sensitization as well as hair fibre damage. The inventive composition addresses the aforementioned disadvantages by providing a hair colour composition comprising: (a) Taxifolin; and (b) A combination of a peroxidase with either a hydrogen peroxide generator or hydrogen peroxide; wherein the composition has a pH of 4.5 to 7.0, preferably less than or equal to 6.0.
摘要翻译：头发着色剂可分为永久性，半永久性和临时性三大类。永久性着色着色剂是氧化染料体系，通常含有对苯二胺（PPD）和间苯二酚，这两者都已被证明会引起致敏和致突变性。此外，需要严重的氧化条件，其本身会引起皮肤刺激和敏化以及头发纤维损伤。本发明的组合物通过提供一种头发颜色组合物来解决上述缺点，该组合物包含：（a）紫杉醇; 和（b）过氧化物酶与过氧化氢发生器或过氧化氢的组合; 其中所述组合物的pH为4.5至7.0，优选小于或等于6.0。

2. 发明申请

WO2015058935A1 ANTI-PERSPIRANT COMPOSITION 审中-公开
标题翻译：抗敏成分
公开(公告)号：WO2015058935A1
公开(公告)日：2015-04-30
申请号：PCT/EP2014/070911
申请日：2014-09-30
申请人： UNILEVER PLC , UNILEVER N.V. , CONOPCO, INC., D/B/A UNILEVER
发明人： BERRY, Mark, John , CASEY, John , HUNTER, Karl, John
IPC分类号： A61Q15/00 , A61K8/73 , A61K8/26
CPC分类号： A61K8/736 , A61K8/26 , A61Q15/00
摘要： The invention relates to use of chitosan or a salt thereof in an anti-perspirant composition as an anti-perspirant ingredient. Current anti-perspirants are based on aluminium, but inorganic salts have the effect of leaving white patches on clothes. Additionally there is a perceived health risk associated with aluminium The current approach is to reduce the amount of aluminium in antiperspirants or to use additional metal salts such as those of zirconium. However, this approach tends to lower the efficacy of the formulation and hence prove more expensive. Zirconium-based antiperspirants tend to leave yellow patches on clothes. Use of chitosan or a salt thereof in an anti-perspirant composition as an anti-perspirant ingredient is provided, wherein the chitosan or salt thereof has a degree of acetylation of 0-15, preferably 0-12, most preferably 0-10 %, wherein the chitosan or salt thereof is either in an anhydrous form or dissolved in water at a pH of no more than 6.0, preferably no more than 5.5, most preferably no more than 5.0.
摘要翻译：本发明涉及壳聚糖或其盐在防汗组合物中作为抗渗透成分的用途。目前的抗汗剂基于铝，但无机盐具有在衣服上留下白色贴片的效果。另外还有与铝有关的健康风险目前的方法是减少止汗剂中的铝量或使用额外的金属盐如锆。然而，这种方法倾向于降低制剂的功效，因此证明更昂贵。锆基止汗剂倾向于在衣服上留下黄色斑块。提供了在防汗组合物中使用壳聚糖或其盐作为抗渗透成分，其中壳聚糖或其盐的乙酰化度为0-15，优选为0-12，最优选为0-10％其中所述壳聚糖或其盐为无水形式或溶于水中，其pH不超过6.0，优选不超过5.5，最优选不超过5.0。

3. 发明申请

WO2014122132A1 TOPICAL COLOURING COMPOSITION 审中-公开
标题翻译：主题色彩组成
公开(公告)号：WO2014122132A1
公开(公告)日：2014-08-14
申请号：PCT/EP2014/052166
申请日：2014-02-04
申请人： UNILEVER PLC , UNILEVER N.V. , CONOPCO, INC., D/B/A UNILEVER
发明人： BHOGAL, Ranjit, Kaur , CASEY, John , GANGULI, Shovan , HUNTER, Karl, John , KOEK, Jean, Hypolites , REDFERN, Sally, Pamela
IPC分类号： A61Q5/10 , A61K8/49 , A61K8/66 , A61Q1/02 , A61Q1/12
CPC分类号： A61Q1/02 , A61K8/498 , A61K8/66 , A61Q5/065
摘要： Hair colourant formulations fall into three main categories designated permanent, semi-permanent and temporary. Permanent hair colourant formulations are oxidative dye systems and generally contain paraphenylene diamine (PPD) and resorcinol, both of which have been shown to cause sensitisation and mutagenicity. Furthermore,severe oxidising conditions are required which in themselves cause skin irritation and sensitization as well as hair fibre damage. The inventive composition addresses the aforementioned disadvantages by providing a topical colour composition comprising: (a) Quercetin; and (b) A laccase, wherein the composition has a pH of 4.5 to 7.0, preferably less than or equal to 6.0.
摘要翻译：头发着色剂可分为永久性，半永久性和临时性三大类。永久性毛发着色剂配方是氧化染料体系，通常含有对苯二胺（PPD）和间苯二酚，这两者都已显示引起致敏和致突变性。此外，需要严重的氧化条件，其本身会引起皮肤刺激和敏化以及头发纤维损伤。本发明的组合物通过提供一种局部颜色组合物来解决上述缺点，包括：（a）槲皮素; 和（b）漆酶，其中所述组合物的pH为4.5至7.0，优选小于或等于6.0。

4. 发明申请

WO2015074821A1 HAIR COLOURING COMPOSITION 审中-公开
标题翻译：头发着色组合物
公开(公告)号：WO2015074821A1
公开(公告)日：2015-05-28
申请号：PCT/EP2014/072724
申请日：2014-10-23
申请人： UNILEVER PLC , UNILEVER N.V. , CONOPCO, INC., D/B/A UNILEVER
发明人： HUNTER, Karl, John
IPC分类号： A61K8/49 , A61Q5/10 , A61K8/66 , A61K8/04
CPC分类号： A61K8/66 , A61K8/046 , A61K8/498 , A61Q5/10
摘要： The invention relates to a hair colour composition. The dyeing of hair using oxidative dyes (including polyphenols) oxidised by atmospheric oxygen (from the air or an air foam) and catalysed by the enzyme laccase is known. As laccase uses atmospheric oxygen to oxidise dyes, its efficiency is limited by both the availability of dissolved oxygen in the aqueous solution in which the enzyme and dyes are applied and also the diffusion of oxygen from air into the solution as the dissolved oxygen is depleted by the reaction. The inventors have observed that significant colour changes are observed over 30 minutes with selected polyphenols when treated with laccase in the presence of oxygen foams. Thus in a first aspect of the invention, a hair colour composition is provided, the hair colour composition comprising: (a) A polyphenol selected from the group consisting of catechin, epicatechin and a mixture thereof; (b) A laccase; (c) A surfactant; and (d) Pure oxygen or an oxygen generator; wherein the pure oxygen or oxygen generated by the oxygen generator is in the form of foam; and wherein the composition has a pH of 4.5 to 7.0, preferably less than or equal to 6.0.
摘要翻译：本发明涉及一种头发颜色组合物。使用氧化染料（包括多酚）染色头发的方法是用大气中的氧气（来自空气或空气泡沫）氧化并被酶漆酶催化。由于漆酶使用大气氧来氧化染料，其效率受到其中施加酶和染料的水溶液中溶解氧的可用性的限制，并且当溶解氧耗尽时，氧气从空气扩散到溶液中反应。发明人已经观察到，在氧气泡沫存在下用漆酶处理时，用选定的多酚在30分钟内观察到显着的颜色变化。因此，在本发明的第一方面中，提供了一种发色组合物，所述发色组合物包含：（a）选自儿茶素，表儿茶素及其混合物的多酚; （b）漆酶; （c）表面活性剂; 和（d）纯氧或氧气发生器; 其中由氧气发生器产生的纯氧气或氧气是泡沫形式; 并且其中所述组合物的pH为4.5至7.0，优选小于或等于6.0。

5. 发明申请

WO2017080945A1 ANTI-PERSPIRANT COMPOSITION 审中-公开
标题翻译：抗皱组合物
公开(公告)号：WO2017080945A1
公开(公告)日：2017-05-18
申请号：PCT/EP2016/076807
申请日：2016-11-07
申请人： UNILEVER PLC , UNILEVER N.V. , CONOPCO, INC., D/B/A UNILEVER
发明人： BERRY, Mark, John , CHANDLER, Ian, Christopher , HUNTER, Karl, John
IPC分类号： A61Q15/00 , A61K8/73 , A61K8/20 , A61K8/26 , A61K8/27 , A61K8/23 , A61K8/19
CPC分类号： A61Q15/00 , A61K8/19 , A61K8/20 , A61K8/23 , A61K8/26 , A61K8/27 , A61K8/736
摘要： An anti-perspirant composition comprising: (a) chitosan or a salt thereof, with a weight average molecular weight of greater than 80 kDa; and (b) an aluminium, zinc, magnesium or copper salt or mixture thereof. wherein the composition comprises less than 3 wt% of aluminium salt.
摘要翻译：一种止汗剂组合物，其包含：（a）重均分子量大于80kDa的壳聚糖或其盐; 和（b）铝，锌，镁或铜盐或其混合物。其中所述组合物包含小于3重量％的铝盐。

6. 发明申请

WO2013189964A3 HAIR COLOURING COMPOSITION COMPRISING GOSSYPETIN 审中-公开
公开(公告)号：WO2013189964A3
公开(公告)日：2013-12-27
申请号：PCT/EP2013/062699
申请日：2013-06-19
申请人： UNILEVER PLC , UNILEVER N.V. , CONOPCO, INC., D/B/A UNILEVER
发明人： BHOGAL, Ranjit, Kaur , CASEY, John , GANGULI, Shovan , HUNTER, Karl, John , KOEK, Jean, Hypolites , REDFERN, Sally, Pamela
IPC分类号： A61K8/49 , A61Q5/06 , A61Q5/10 , A61K8/97 , A61K8/22
摘要： Hair colourant formulations fall into three main categories designated permanent, semi-permanent and temporary. Permanent hair colourant formulations are oxidative dye systems and generally contain paraphenylene diamine (PPD) and resorcinol, both of which have been shown to cause sensitisation and mutagenicity. Furthermore, severe oxidising conditions are required which in themselves cause skin irritation and sensitization as well as hair fibre damage. The inventive composition addresses the aforementioned disadvantages by providing a hair colour composition comprising: (a) Gossypetin; and either (b1 ) A combination of a peroxidase with either a hydrogen peroxide generator or hydrogen peroxide, or (b2) a laccase; wherein the composition has a pH of 4.5 to 7.0, preferably less than or equal to 6.0.

7. 发明申请

WO2013079536A1 A MEAL INTENDED FOR HUMAN CONSUMPTION 审中-公开
标题翻译：用于人类消费的美食
公开(公告)号：WO2013079536A1
公开(公告)日：2013-06-06
申请号：PCT/EP2012/073846
申请日：2012-11-28
申请人： UNILEVER PLC , UNILEVER N.V. , HINDUSTAN UNILEVER LIMITED , CONOPCO, INC., D/B/A UNILEVER
发明人： BERRY, Mark, John , BLIGH, Heather, Frances, Jennifer , FOWLER, Mark, Ian , HUNTER, Karl, John , MACAULAY, Katrina
IPC分类号： A23L1/29 , A23L1/30 , A23L1/308
CPC分类号： A23L33/21 , A23L33/105 , A23L33/17 , A23L33/30 , A23L33/40 , A23V2002/00
摘要： This invention relates to a plurality of compositions for dietary health management and its use in the prevention or treatment of cardiovascular disease or type 2 diabetes, and also in the prevention and/or management of obesity and generally in weight management and loss. Thus a meal intended for human consumption is provided, the meal comprising: (a) 250-650 kilocalories (1045 - 4180 kiloJoules); (b) 10-50, preferably 20-50, more preferably 30-50 g fibre; (c) 10-50, preferably 10-30, more preferably 10-20 g protein; (d) 0 to 5, preferably less than 3 g starch; and (e) 0 to 2, preferably 0 to 1, most preferably 0 to 0.5 g lactose; (f) at least 20, preferably at least 30, most preferably at least 40 mg of any one flavonoid aglycone; and (g) at least 30, preferably at least 40, most preferably at least 50 mg of any one flavonoid glucoside; wherein the meal comprises 75-1000 mg of total flavonoid aglycone and flavonoid glucoside, wherein the meal comprises no more than 250 mg of any one flavonoid aglycone, wherein the meal comprises no more than 250 mg of any one flavonoid glucoside.
摘要翻译：本发明涉及用于饮食健康管理的多种组合物及其在预防或治疗心血管疾病或2型糖尿病中的用途，以及用于预防和/或控制肥胖症以及通常在体重管理和损失中的用途。因此，提供用于人类消费的膳食，膳食包括：（a）250-650千卡（1045-4180千焦耳）; （b）10-50，优选20-50，更优选30-50g纤维; （c）10-50，优选10-30，更优选10-20g蛋白质; （d）0-5，优选小于3g淀粉; 和（e）0至2，优选0至1，最优选0至0.5g乳糖; （f）至少20，优选至少30，最优选至少40mg的任何一种类黄酮糖苷配基; 和（g）至少30，优选至少40，最优选至少50mg的任何一种类黄酮糖苷; 其中所述膳食包含75-1000mg的总黄酮糖苷配基和类黄酮糖苷，其中所述膳食不超过250mg的任何一种类黄酮糖苷配基，其中所述膳食不超过250mg的任何一种类黄酮糖苷。

8. 发明申请

WO2018099931A1 ANTI-PERSPIRANT COMPOSITION COMPRISING CHITOSAN 审中-公开
公开(公告)号：WO2018099931A1
公开(公告)日：2018-06-07
申请号：PCT/EP2017/080728
申请日：2017-11-28
申请人： UNILEVER PLC , UNILEVER N.V. , CONOPCO, INC., D/B/A UNILEVER
发明人： CHANDLER, Ian, Christopher , BERRY, Mark, John , HUNTER, Karl, John , WILLIAMS, Jason, Richard , ZHOU, Huanjun , ZHU, Shuqi
IPC分类号： A61Q15/00 , A61K8/73
CPC分类号： A61Q15/00 , A61K8/736
摘要： An anti-perspirant composition comprising chitosan or a salt thereof, with a weight average molecular weight of from 250 to 650 kDa.

9. 发明申请

WO2013189966A3 HAIR COLOURING COMPOSITION COMPRISING BUTEIN 审中-公开
公开(公告)号：WO2013189966A3
公开(公告)日：2013-12-27
申请号：PCT/EP2013/062701
申请日：2013-06-19
申请人： UNILEVER PLC , UNILEVER N.V. , CONOPCO, INC., d/b/a UNILEVER
发明人： BHOGAL, Ranjit, Kaur , CASEY, John , GANGULI, Shovan , HUNTER, Karl, John , KOEK, Jean, Hypolites , REDFERN, Sally, Pamela
IPC分类号： A61K8/35 , A61Q5/06 , A61Q5/10 , A61K8/97 , A61K8/22
摘要： Hair colourant formulations fall into three main categories designated permanent, semi-permanent and temporary. Permanent hair colourant formulations are oxidative dye systems and generally contain paraphenylene diamine (PPD) and resorcinol, both of which have been shown to cause sensitisation and mutagenicity. Furthermore, severe oxidising conditions are required which in themselves cause skin irritation and sensitization as well as hair fibre damage. The inventive composition addresses the aforementioned disadvantages by providing a hair colour composition comprising: (a) Butein; and either (b1 ) A combination of a peroxidase with either a hydrogen peroxide generator or hydrogen peroxide, or (b2) a laccase; wherein the composition has a pH of 4.5 to 7.0, preferably less than or equal to 6.0.

10. 发明申请

WO2013083510A2 HAIR COLOUR COMPOSITION 审中-公开
标题翻译：头发颜色组成
公开(公告)号：WO2013083510A2
公开(公告)日：2013-06-13
申请号：PCT/EP2012/074204
申请日：2012-12-03
申请人： UNILEVER PLC , UNILEVER N.V. , HINDUSTAN UNILEVER LIMITED , CONOPCO, INC.
发明人： BHOGAL, Ranjit, Kaur , CASEY, John , HUNTER, Karl, John
IPC分类号： A61K8/22 , A61K8/49 , A61Q5/06 , A61Q5/10
CPC分类号： A61K8/49 , A61K8/19 , A61K8/22 , A61K8/4913 , A61Q5/065 , A61Q5/10
摘要： The invention relates to a hair colour composition, in particular a hair colour composition comprising a flavonoid, a catalyst consisting of iron (II) or cobalt (II) complexed to a non-proteinaceous heterocyclic macrocycle ligand composed of pyrrole or pyrroline subunits, and either a hydrogen peroxide generator or 0.0001 to less than 1.5 % w/w hydrogen peroxide. The flavonoid is selected from the group consisting of flavones, isoflavones, flavans, isoflavans, flavanones, flavonols, flavan-3-ols, dihydroflavonol, flavanonols, proanthocyanidins, aurones, chalcones, dihydrochalcones, flavonolignans, and derivatives thereof, wherein the hair colour composition has a pH of 4.5 to 8.0, preferably 5.5 to 7.5.
摘要翻译：本发明涉及一种发色组合物，特别是包含类黄酮的发色组合物，由与吡咯或吡咯啉亚基组成的非蛋白质杂环大环配体络合的铁（II）或钴（II）组成的催化剂，以及过氧化氢发生剂或0.0001至小于1.5％w / w过氧化氢。黄酮类化合物选自黄酮，异黄酮，黄烷，异黄酮，黄酮酮，黄酮醇，黄烷-3-醇，二氢黄酮醇，黄烷醇，原花色素，噢，，查尔酮，二氢查耳酮，黄酮醇酐及其衍生物， pH为4.5〜8.0，优选为5.5〜7.5。

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